Page last updated: 2024-11-06

reserpine and Arteriosclerosis

reserpine has been researched along with Arteriosclerosis in 47 studies

Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.

Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.

Research Excerpts

ExcerptRelevanceReference
"Reserpine was injected intraperitoneally, followed immediately by the administration of [3H]cholesterol by gavage."1.31Effect of reserpine treatment on low-density lipoproteins in arterial wall and internal organs of rats. ( Born, GV; Brown, J; Shafi, S; Weidinger, G; Welzel, D, 2000)
"The treatment of both hyperlipidemia and hypertension appeared to be more effective than the treatment of hyperlipidemia, alone."1.26Aggravation of atherosclerosis by hypertension in a subhuman primate model with coarctation of the aorta. ( Hollander, W; Kirkpatrick, B; Madoff, I; Paddock, J, 1976)

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199045 (95.74)18.7374
1990's0 (0.00)18.2507
2000's2 (4.26)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
GARIN, L1
LUBECK, I1
SCHEFFLER, C1
BARUCCI, M1
MORI, F1
SMITH, TH1
ROSSI, GV1
SEBRANJOBRIZ, F1
BOETTIGER, LE1
MALMBORG, RO1
MICHAELI, EW1
BLOK, Ie1
OBROWSKY, L1
TOLMASSKAIA, ES1
ARSHAVSKII, VV1
Weber, GF1
Batson, HM1
Birchall, R1
Melli, A1
Golinelli, G1
Yang, YZ1
Tsfasman, AZ1
Zhuravleva, GN1
Bronskiĭ, VI1
Gaĭtsgori, ES1
Sinaĭskaia, TN1
Taylor, LM1
Rivers, SP1
Keller, FS1
Baur, GM1
Porter, JM1
Kulagina, VP1
Firsov, NN1
Feld, LG1
Van Liew, JB1
Brentjens, JR1
Boylan, JW1
Shafi, S2
Stepanova, IP1
Fitzsimmons, C1
Bowyer, DE1
Welzel, D2
Born, GV2
Weidinger, G1
Brown, J1
Hollander, W1
Madoff, I1
Paddock, J1
Kirkpatrick, B1
Voudoukis, IJ1
Davis, PJ1
Davis, FB1
Menotti, A1
Puddu, V1
Kattus, AA1
Buchborn, E1
Holzgreve, H1
Tondiĭ, LD1
Worowski, K1
Prokopowicz, J1
Gabryelewicz, A1
Nityanand, S1
Shipstone, AC1
Kapoor, NK1
Freis, ED1
Chasis, H1
Vara, R1
Vara-Thorbeck, R1
Carranza Albarran, G1
Negoita, CJ1
Raso, AM1
Silvestrini, P1
Chassin, MR1
Sulivan, JM1
Bock, KD1
Britov, AN1
Siderskiĭ, AL1
Piro, E1
Levi, GF2
Proto, C2
Schütz, E1
Ludwig, H1
Thielecke, R1
Weichert, G1
Grimaldi, MG2
Scalabrino, R1
Whittington-Coleman, PJ2
Carrier, O2
Clower, BR2
Grasso, G1
Lauridsen, P1
Mad'ar, J1
Havris, S1
Tretenhahn, W1

Reviews

2 reviews available for reserpine and Arteriosclerosis

ArticleYear
The treatment of hypertension. Why, when and how.
    The American journal of medicine, 1972, Volume: 52, Issue:5

    Topics: Arteriosclerosis; Cardiovascular Diseases; Diuretics; Female; Guanethidine; Humans; Hydralazine; Hyd

1972
[Gastro-duodenal disorders in patients with cardiovascular diseases].
    Kardiologiia, 1971, Volume: 11, Issue:8

    Topics: Adrenal Cortex Hormones; Animals; Arteriosclerosis; Cardiovascular Diseases; Cats; Cerebrovascular D

1971

Trials

2 trials available for reserpine and Arteriosclerosis

ArticleYear
[Treatment of sclerotic systolic hypertension].
    Sovetskaia meditsina, 1980, Issue:6

    Topics: Aged; Alkaloids; Antihypertensive Agents; Arteriosclerosis; Clinical Trials as Topic; Clonidine; Dru

1980
Appraisal of antihypertensive drug therapy.
    Circulation, 1974, Volume: 50, Issue:1

    Topics: Antihypertensive Agents; Arteriosclerosis; Clinical Trials as Topic; Coronary Disease; Diabetes Comp

1974

Other Studies

43 other studies available for reserpine and Arteriosclerosis

ArticleYear
[Preliminary clinical and experimental considerations on the effect of reserpine on modifications of lesser circulation].
    Rivista critica di clinica medica, 1954, Oct-31, Volume: 54, Issue:5

    Topics: Antihypertensive Agents; Arteries; Arteriosclerosis; Cardiovascular System; Disease; Pulmonary Arter

1954
[Relation between pulse wave celerity, blood pressure and capillary resistance in labile and fixed hypertension and arteriosclerosis under comparative medication by Rauwolfia serpentina Benth and a horse chestnut-rutin preparation].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1957, Jun-01, Volume: 12, Issue:11

    Topics: Aesculus; Anticoagulants; Arteriosclerosis; Blood Pressure; Blood Pressure Determination; Capillary

1957
[Effects of reserpine combined with a psycho-analeptic drug on mental efficiency of the aged].
    Rivista di patologia nervosa e mentale, 1957, Volume: 78, Issue:3

    Topics: Aged; Arteriosclerosis; Central Nervous System Stimulants; Dementia; Mental Disorders; Methylphenida

1957
The effect of reserpine and mecamylamine on experimental atheromatosis in the normotensive and hypertensive rat.
    The Journal of pharmacology and experimental therapeutics, 1962, Volume: 135

    Topics: Animals; Arteriosclerosis; Autonomic Agents; Blood Pressure; Cholesterol; Hypertension; Mecamylamine

1962
[TREATMENT OF HYPERTENSION WITH HYGROTON-RESERPINE].
    Medicina clinica, 1963, Volume: 41

    Topics: Arteriosclerosis; Chlorthalidone; Clinical Laboratory Techniques; Electrocardiography; Guanethidine;

1963
[SEVERE NEUROLOGICAL SIDE-EFFECTS IN HYPOTENSION THERAPY].
    Nordisk medicin, 1964, Apr-23, Volume: 71

    Topics: Amobarbital; Antihypertensive Agents; Arteriosclerosis; Chlorothiazide; Chlorthalidone; Guanethidine

1964
[TISSUE CULTURE OF THE AORTA OF ADULT RABBITS AND MAN].
    Biulleten' eksperimental'noi biologii i meditsiny, 1964, Volume: 57

    Topics: Animals; Aorta; Arteriosclerosis; Lagomorpha; Rabbits; Research; Reserpine; Tissue Culture Technique

1964
[CLINICAL EXPERIENCES WITH THE ANTIHYPERTENSIVE AGENT HYGROTON-RESERPINE].
    Wiener medizinische Wochenschrift (1946), 1964, Mar-14, Volume: 114

    Topics: Antihypertensive Agents; Arteriosclerosis; Biomedical Research; Chlorthalidone; Drug Therapy; Hypert

1964
[ON THE ELECTROPHYSIOLOGIC ANALYSIS OF THE CENTRAL ACTION OF RESERPINE].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1964, Volume: 64

    Topics: Arteriosclerosis; Catatonia; Chorea; Drug Therapy; Electroencephalography; Hypertension; Mental Diso

1964
Arteriosclerotic hypertension often misdiagnosed, overtreated.
    Geriatrics, 1967, Volume: 22, Issue:11

    Topics: Arteriosclerosis; Humans; Hypertension; Methyldopa; Phenobarbital; Prognosis; Reserpine

1967
[Clinical studies of the vasodilating activity of a new drug with adrenosympatholytic action].
    Minerva cardioangiologica, 1967, Volume: 15, Issue:6

    Topics: Adult; Aged; Arteriosclerosis; Endarteritis; Ergot Alkaloids; Female; Heart Diseases; Humans; Intrac

1967
[Experimental study on the inhibition of atherosclerosis by reserpine].
    Zhonghua xin xue guan bing za zhi, 1983, Volume: 11, Issue:4

    Topics: Animals; Arteriosclerosis; Blood Platelets; Cholesterol; Female; Male; Rabbits; Reserpine

1983
Treatment of finger ischemia with Bier block reserpine.
    Surgery, gynecology & obstetrics, 1982, Volume: 154, Issue:1

    Topics: Adult; Arterial Occlusive Diseases; Arteriosclerosis; Female; Fingers; Humans; Injections, Intraveno

1982
[Relaxation of the rabbit abdominal aorta in response to the distention of its wall in various functional states].
    Kardiologiia, 1981, Volume: 21, Issue:1

    Topics: Animals; Aorta, Abdominal; Aortic Diseases; Arteriosclerosis; Culture Media; Culture Techniques; Ele

1981
Renal lesions and proteinuria in the spontaneously hypertensive rat made normotensive by treatment.
    Kidney international, 1981, Volume: 20, Issue:5

    Topics: Age Factors; Animals; Arteriosclerosis; Blood Pressure; Chlorothiazide; Hydralazine; Hypertension; K

1981
Effects of reserpine on expression of the LDL receptor in liver and on plasma and tissue lipids, low density lipoprotein and fibrinogen in rabbits in vivo.
    Atherosclerosis, 2000, Volume: 149, Issue:2

    Topics: Animals; Arteriosclerosis; Culture Techniques; Disease Models, Animal; Ethinyl Estradiol; Fibrinogen

2000
Effect of reserpine treatment on low-density lipoproteins in arterial wall and internal organs of rats.
    Journal of cardiovascular pharmacology, 2000, Volume: 35, Issue:5

    Topics: Adrenal Glands; Animals; Arteries; Arteriosclerosis; Blood Pressure; Cholesterol; Epinephrine; Heart

2000
Aggravation of atherosclerosis by hypertension in a subhuman primate model with coarctation of the aorta.
    Circulation research, 1976, Volume: 38, Issue:6 Suppl 2

    Topics: Animals; Aortic Coarctation; Arteriosclerosis; Blood Pressure; Body Weight; Cholesterol, Dietary; Co

1976
Prognostic and therapeutic considerations in pure hypertension vs hypertension and superimposed arteriosclerosis.
    Angiology, 1975, Volume: 26, Issue:1 Pt. 1

    Topics: Arteriosclerosis; Blood Pressure; Cold Temperature; Digitalis; Female; Follow-Up Studies; Humans; Hy

1975
Hyperthyroidism in patients over the age of 60 years. Clinical features in 85 patients.
    Medicine, 1974, Volume: 53, Issue:3

    Topics: Age Factors; Aged; Arteriosclerosis; Blood Glucose; Blood Sedimentation; Body Weight; Calcium; Chole

1974
[Short-term pilot study of the feasibility of multifactor reduction of coronary risk].
    Giornale italiano di cardiologia, 1973, Volume: 3, Issue:2

    Topics: Adult; Arteriosclerosis; Clofibrate; Clopamide; Coronary Disease; Diet Therapy; Dietary Fats; Ergolo

1973
Exercise electrocardiography: recognition of the ischemic response, false positive and negative patterns.
    The American journal of cardiology, 1974, May-20, Volume: 33, Issue:6

    Topics: Action Potentials; Angina Pectoris; Arteriosclerosis; Chlorothiazide; Coronary Disease; Diagnostic E

1974
[Differential diagnosis and pharmacotherapy of hypertension (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1974, Mar-22, Volume: 116, Issue:12

    Topics: Arteriosclerosis; Coronary Disease; Diagnosis, Differential; Diuretics; Electrocardiography; Guaneth

1974
[The treatment of patients with hypertension].
    Vrachebnoe delo, 1966, Volume: 7

    Topics: Aged; Arteriosclerosis; Female; Humans; Hypertension; Male; Middle Aged; Niacinamide; Reserpine; Rut

1966
Plasma fibrinolytic system and blood pressure in patients with hypertensive cardiovascular disease treated with reserpine and phenformin.
    Haematologia, 1970, Volume: 4, Issue:3

    Topics: Adult; Aged; Arteriosclerosis; Blood Pressure; Enzyme Activation; Female; Fibrinogen; Fibrinolysin;

1970
Electron microscopic & biochemical study of atheromatous lesion & their prevention by reserpine.
    Indian journal of experimental biology, 1974, Volume: 12, Issue:2

    Topics: Animals; Aorta; Arteriosclerosis; Lipids; Male; Microscopy, Electron; Rabbits; Reserpine

1974
[Effects of lumbar sympathectomy as determinated by electromagnetic rheometry].
    Zentralblatt fur Chirurgie, 1972, Dec-09, Volume: 97, Issue:49

    Topics: Adult; Aged; Arteriosclerosis; Femoral Artery; Humans; Iliac Artery; Injections, Intra-Arterial; Leg

1972
[Present status in pathogenesis, diagnosis and therapy of arterial hypertension].
    Giornale di clinica medica, 1972, Volume: 53, Issue:10

    Topics: Arteriosclerosis; Guanethidine; Hemodynamics; Humans; Hypertension; Obesity; Reserpine

1972
[Prolonged intravenous and intra-arterial administration of large doses of Raubasine in peripheral arterial diseases].
    Minerva medica, 1973, Mar-29, Volume: 64, Issue:19

    Topics: Adult; Aged; Ajmaline; Aneurysm; Arteriosclerosis; Diabetic Angiopathies; Embolism; Female; Humans;

1973
Pharmacologic management of renovascular hypertension.
    JAMA, 1974, Jan-28, Volume: 227, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Arteriosclerosis; Blood Pressure Determination; Diuretics; Dru

1974
[What is reliable in the therapy of hypertension?].
    Der Internist, 1970, Volume: 11, Issue:12

    Topics: Arteriosclerosis; Cerebral Hemorrhage; Diet, Reducing; Diet, Sodium-Restricted; Guanethidine; Health

1970
[Use of a hypotensive agent with a furosemide-reserpine base in therapy].
    Minerva medica, 1972, Apr-28, Volume: 63, Issue:32

    Topics: Aged; Arteriosclerosis; Drug Combinations; Drug Synergism; Furosemide; Humans; Hypertension; Hyperte

1972
[Long-term treatment of hypertensive disease "in the vascular sclerosis phase" with furosemide and reserpine. Clinico-statistical and hematochemical considerations].
    Minerva cardioangiologica, 1970, Volume: 18, Issue:3

    Topics: Adult; Aged; Arteriosclerosis; Blood Glucose; Electrolytes; Female; Furosemide; Humans; Hypertension

1970
[Ambulatory therapy of hypertension with briserin mite].
    Die Medizinische Welt, 1970, May-30, Volume: 22

    Topics: Adult; Aged; Ambulatory Care; Amides; Antihypertensive Agents; Arteriosclerosis; Clopamide; Diuretic

1970
[Effect of a combination of dihydroergocristine methanesulfonate, clopamide and reserpine on blood pressure and renal hemodynamics in renal and essential hypertension].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:8

    Topics: Adult; Aged; Amides; Antihypertensive Agents; Arteries; Arteriosclerosis; Blood Pressure; Clopamide;

1970
[Prolonged treatment of arterial hypertension of arteriosclerotic origin with a combination of chlorthalidone and reserpine].
    La Clinica terapeutica, 1967, Mar-31, Volume: 40, Issue:6

    Topics: Aged; Arteriosclerosis; Blood Glucose; Chlorthalidone; Diuresis; Electrolytes; Female; Hemodynamics;

1967
[Changes in blood uric acid during prolonged treatment with diuretic-hypotensive drugs in aged patients].
    Giornale di gerontologia, 1967, Volume: 15, Issue:3

    Topics: Aged; Arteriosclerosis; Chlorthalidone; Female; Humans; Hypertension; Male; Middle Aged; Reserpine;

1967
The effects of reserpine on vasopressin-cholesterol-induced atheromatous lesions.
    The Journal of pharmacology and experimental therapeutics, 1968, Volume: 160, Issue:1

    Topics: Animals; Aorta; Arteriosclerosis; Blood Pressure; Body Weight; Calcium; Cholesterol; Diet; Female; L

1968
[The treatment of arterial hypertension in the vascular sclerosis phase with the association of furosemide and reserpine].
    Minerva medica, 1968, Oct-06, Volume: 59, Issue:80

    Topics: Adult; Aged; Arteriosclerosis; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Reserpin

1968
Comparison between flow and flow pattern in normal and arteriosclerotic vessels as well as before and after intra-arterial injection of reserpine.
    Danish medical bulletin, 1968, Volume: 15, Issue:7

    Topics: Adult; Aged; Arteriosclerosis; Female; Humans; Male; Middle Aged; Regional Blood Flow; Reserpine

1968
Reserpine inhibition of coronary arteriosclerosis.
    Canadian journal of physiology and pharmacology, 1969, Volume: 47, Issue:1

    Topics: Animals; Arteriosclerosis; Cholesterol; Coronary Disease; Dietary Fats; Rabbits; Reserpine; Vasopres

1969
[Effect of reserpine on experimental arteriosclerosis].
    Bratislavske lekarske listy, 1969, Volume: 51, Issue:5

    Topics: Animals; Arteriosclerosis; Cholesterol; Drug Synergism; Female; Hypertension; Male; Rabbits; Reserpi

1969
[The treatment of hypertension].
    Wiener medizinische Wochenschrift (1946), 1966, May-21, Volume: 116, Issue:21

    Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Arteriosclerosis; Child; Child, Preschool; Coronar

1966