reserpine has been researched along with Angelman Syndrome in 1 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Angelman Syndrome: A syndrome characterized by multiple abnormalities, MENTAL RETARDATION, and movement disorders. Present usually are skull and other abnormalities, frequent infantile spasms (SPASMS, INFANTILE); easily provoked and prolonged paroxysms of laughter (hence happy); jerky puppetlike movements (hence puppet); continuous tongue protrusion; motor retardation; ATAXIA; MUSCLE HYPOTONIA; and a peculiar facies. It is associated with maternal deletions of chromosome 15q11-13 and other genetic abnormalities. (From Am J Med Genet 1998 Dec 4;80(4):385-90; Hum Mol Genet 1999 Jan;8(1):129-35)
| Excerpt | Relevance | Reference |
|---|---|---|
| "This myoclonus was unresponsive to benztropine, clonazepam and worsened with bromocriptine." | 5.32 | Reserpine responsive myoclonus and hyperpyrexia in a patient with Angelman syndrome. ( Myers, SM; Stecker, MM, 2003) |
| "This myoclonus was unresponsive to benztropine, clonazepam and worsened with bromocriptine." | 1.32 | Reserpine responsive myoclonus and hyperpyrexia in a patient with Angelman syndrome. ( Myers, SM; Stecker, MM, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stecker, MM | 1 |
| Myers, SM | 1 |
1 other study available for reserpine and Angelman Syndrome
| Article | Year |
|---|---|
Reserpine responsive myoclonus and hyperpyrexia in a patient with Angelman syndrome.
Topics: Adult; Angelman Syndrome; Anticonvulsants; Chromosomes, Human, Pair 15; Clonazepam; Drug Therapy, Co | 2003 |