Page last updated: 2024-11-06

reserpine and Adverse Drug Event

reserpine has been researched along with Adverse Drug Event in 29 studies

Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.

Research Excerpts

ExcerptRelevanceReference
" Intermittently elevated prolactin levels have been noted in some women who subsequently developed breast cancer, but epidemiologic studies of women who have received prolactin-releasing drugs such as reserpine and perphenazine have not disclosed increased risk."3.66Hormones, medications, and cancer. ( Lipsett, MB, 1983)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199024 (82.76)18.7374
1990's0 (0.00)18.2507
2000's2 (6.90)29.6817
2010's3 (10.34)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pedersen, JM1
Matsson, P1
Bergström, CA1
Norinder, U1
Hoogstraate, J1
Artursson, P1
Liu, Z1
Shi, Q1
Ding, D1
Kelly, R1
Fang, H1
Tong, W1
Morgan, RE1
van Staden, CJ1
Chen, Y1
Kalyanaraman, N1
Kalanzi, J1
Dunn, RT1
Afshari, CA1
Hamadeh, HK1
Tachere, RO1
Modirrousta, M1
PERITI, P1
STIRSKA, J1
STEPAN, J1
OVERGAARD, J1
MISSERE, G1
BABBINI, M1
TONINI, G1
MARESOVA, J1
DICK, HL1
McCAWLEY, EL1
FISHER, WA1
Slotkin, TA1
Ribelin, WE1
Lipsett, MB1
Torrini, M1
Masini, E1
Ledda, F1
Mannaioni, PF1
Yuan, J1
Cord, BJ1
McCann, UD1
Callahan, BT1
Ricaurte, GA1
Rümke, CL1
Reus, VI1
Komakhidze, ME1
Akhmeteli, TI1
Khundadze, SSh1
Dzneladze, LT1
Gvasaliia, GN1
Daniele, E1
De Nardo, D1
Belousova, IM1
Janssen, F1
Cooke, AR1
Okla, J1
Thurn, G1
Andersson, S1
Chase, TN1
Leuridan, B1

Reviews

5 reviews available for reserpine and Adverse Drug Event

ArticleYear
The cardiac-sympathetic axis as a teratological model.
    Progress in clinical and biological research, 1983, Volume: 140

    Topics: Animals; Animals, Newborn; Catecholamines; Central Nervous System; Drug-Related Side Effects and Adv

1983
[Acute drug-induced extrapyramidal syndrome: case studies of a decade at the autonomous toxicology department of the Arcispedale].
    La Clinica terapeutica, 1981, Jun-30, Volume: 97, Issue:6

    Topics: Adolescent; Adult; Aged; Basal Ganglia Diseases; Benzamides; Butyrophenones; Child; Drug-Related Sid

1981
[Report on the incidence and pathogenetic problems of drug-induced gastroduodenal lesions].
    La Clinica terapeutica, 1978, Apr-15, Volume: 85, Issue:1

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Drug-Related Side Effects and Adverse Reactions; Est

1978
[Administration of some drugs to pregnant or breast feeding women].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1972, Dec-25, Volume: 27, Issue:52

    Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Anti-Bacterial Agents; Anticoagulants; Antineo

1972
Drug-induced extrapyramidal disorders.
    Research publications - Association for Research in Nervous and Mental Disease, 1972, Volume: 50

    Topics: Antiparkinson Agents; Apomorphine; Basal Ganglia Diseases; Benztropine; Dihydroxyphenylalanine; Dopa

1972

Other Studies

24 other studies available for reserpine and Adverse Drug Event

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Bi

2008
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily

2013
Beyond anxiety and agitation: A clinical approach to akathisia.
    Australian family physician, 2017, Volume: 46, Issue:5

    Topics: Adult; Antidepressive Agents; Antiemetics; Antipsychotic Agents; Anxiety; Buspirone; Cinnarizine; Di

2017
[Acute accidental reserpine poisoning in an eighteen month old infant].
    Minerva pediatrica, 1956, Apr-28, Volume: 8, Issue:17

    Topics: Antihypertensive Agents; Child; Drug-Related Side Effects and Adverse Reactions; Humans; Infant; Poi

1956
[Reserpine poisoning in small children].
    Deutsche medizinische Wochenschrift (1946), 1957, Nov-15, Volume: 82, Issue:46

    Topics: Child; Drug-Related Side Effects and Adverse Reactions; Humans; Reserpine

1957
[Effects of reserpine & 5-hydroxytryptamine, with reference to a case of serpasil poisoning in a two year old child].
    Ugeskrift for laeger, 1957, Oct-03, Volume: 119, Issue:40

    Topics: Drug-Related Side Effects and Adverse Reactions; Humans; Malignant Carcinoid Syndrome; Reserpine; Se

1957
[Research on chronic morphine poisoning. II. Effects of reserpine, chlorpromazine & N-allylnormorphine on activity manifestations induced by morphine].
    Bollettino della Societa italiana di biologia sperimentale, 1959, Jun-30, Volume: 35, Issue:12

    Topics: Chlorpromazine; Chronic Disease; Drug-Related Side Effects and Adverse Reactions; Morphine; Nalorphi

1959
[Reserpine poisoning in childhood].
    Ceskoslovenska pediatrie, 1960, Sep-05, Volume: 15

    Topics: Drug-Related Side Effects and Adverse Reactions; Reserpine

1960
Reserpine-digitalis toxicity. Case reports of cardiac arrhythmias occurring during reserpine-digitalis therapy and a review of the literature with supporting animal experiments.
    Archives of internal medicine, 1962, Volume: 109

    Topics: Animal Experimentation; Animals; Arrhythmias, Cardiac; Digitalis; Drug-Related Side Effects and Adve

1962
The effects of drugs and chemicals upon the structure of the adrenal gland.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1984, Volume: 4, Issue:1

    Topics: Adrenal Cortex; Adrenal Gland Diseases; Adrenal Glands; Adrenal Medulla; Animals; Cricetinae; Dogs;

1984
Hormones, medications, and cancer.
    Cancer, 1983, Jun-15, Volume: 51, Issue:12 Suppl

    Topics: Animals; Breast Neoplasms; Cocarcinogenesis; Drug-Related Side Effects and Adverse Reactions; Epidem

1983
Effect of depleting vesicular and cytoplasmic dopamine on methylenedioxymethamphetamine neurotoxicity.
    Journal of neurochemistry, 2002, Volume: 80, Issue:6

    Topics: Adrenergic Uptake Inhibitors; alpha-Methyltyrosine; Animals; Corpus Striatum; Cytoplasm; Cytoplasmic

2002
[Objectionable conservatism or sensible policy in pharmacotherapy?].
    Nederlands tijdschrift voor geneeskunde, 1976, Jan-03, Volume: 120, Issue:1

    Topics: Central Nervous System Stimulants; Child; Clioquinol; Diethylstilbestrol; Drug-Related Side Effects

1976
Behavioral side effects of medical drugs.
    Primary care, 1979, Volume: 6, Issue:2

    Topics: Adrenal Cortex Hormones; Aged; Antihypertensive Agents; Antitubercular Agents; Aspirin; Behavior; Ca

1979
[Gastrointestinal hemorrhages as a consequence of the side effects of drug substances].
    Vestnik khirurgii imeni I. I. Grekova, 1977, Volume: 119, Issue:10

    Topics: Aspirin; Blood Volume; Drug-Related Side Effects and Adverse Reactions; Female; Gastrointestinal Hem

1977
[Gastrointestinal hemorrhage caused by side effect of drugs].
    Klinicheskaia meditsina, 1976, Volume: 54, Issue:10

    Topics: Adult; Aged; Aspirin; Butadienes; Drug-Related Side Effects and Adverse Reactions; Female; Humans; I

1976
[Diseases caused by drug therapy in newborn babies].
    Monatsschrift fur Kinderheilkunde, 1975, Volume: 123, Issue:1

    Topics: Apgar Score; Diazepam; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Female; H

1975
Drugs and gastric damage.
    Drugs, 1976, Volume: 11, Issue:1

    Topics: Adrenal Cortex Hormones; Aspirin; Buffers; Caffeine; Drug Compounding; Drug-Related Side Effects and

1976
[Side effects of various drugs acting on the eye].
    Fortschritte der Medizin, 1972, Jun-01, Volume: 90, Issue:16

    Topics: Cardiac Glycosides; Chloroquine; Contraceptives, Oral; Cyproheptadine; Drug-Related Side Effects and

1972
When a drug is the culprit.
    Geriatrics, 1973, Volume: 28, Issue:9

    Topics: Adult; Aged; Angina Pectoris; Arrhythmias, Cardiac; Clofibrate; Depression; Drug-Related Side Effect

1973
[Side effects of drugs. 2. Gastrointestinal side effects].
    Lakartidningen, 1969, Dec-15, Volume: 66

    Topics: Adrenocorticotropic Hormone; Caffeine; Drug-Related Side Effects and Adverse Reactions; Gastrointest

1969
Psychiatric complications of medical drugs.
    The Medical journal of Australia, 1973, Jun-30, Volume: 1, Issue:26

    Topics: Adrenal Cortex Hormones; Digitalis Glycosides; Dihydroxyphenylalanine; Drug-Related Side Effects and

1973
[Digestive hemorrhages of medicamentous origin].
    Journal des sciences medicales de Lille, 1971, Volume: 89, Issue:11

    Topics: Aminosalicylic Acids; Anti-Inflammatory Agents; Anticoagulants; Drug-Related Side Effects and Advers

1971