reserpine has been researched along with Adenocarcinoma in 10 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
Adenocarcinoma: A malignant epithelial tumor with a glandular organization.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Reserpine, a non-mutagenic mammary gland carcinogen, was administered under the same protocol, but the high control rates of mammary gland adenocarcinomas in the TG-M and TG-NK strains made it difficult to detect any tumor-enhancing effect of reserpine." | 3.68 | Chemical effects in transgenic mice bearing oncogenes expressed in mammary tissue. ( Braun, AG; Rao, GN; Russfield, A; Seilkop, S; Tennant, RW, 1993) |
| "Nine patients with thyroid cancer were treated with reserpine in an attempt to reduce radiation exposure to the salivary glands from 100-150 mCi doses of I-131 therapy to thyroid remnants or metastases." | 1.27 | Effect of reserpine on salivary gland radioiodine uptake in thyroid cancer. ( Levy, HA; Park, CH, 1987) |
| " DL-152 was found to be toxic to cells of all the tumor models tested (KHT fibrosarcoma, RIF-1 fibrosarcoma, EMT-6 adenocarcinoma and Lewis lung carcinoma) when the drug was given by intraperitoneal injection to the tumor-bearing mouse and cell survival was measured by excision assay." | 1.27 | Factors influencing the toxicity of diethylaminoethylreserpine to tumor cells: studies with four transplantable tumors. ( Lehnert, S, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schuetz, EG | 1 |
| Beck, WT | 1 |
| Schuetz, JD | 1 |
| Nilsson, O | 1 |
| Jakobsen, AM | 1 |
| Kölby, L | 1 |
| Bernhardt, P | 1 |
| Forssell-Aronsson, E | 1 |
| Ahlman, H | 1 |
| Ebert, B | 1 |
| Seidel, A | 1 |
| Lampen, A | 1 |
| Lehnert, S | 2 |
| Fisher, G | 1 |
| Methot, G | 1 |
| Tennant, RW | 1 |
| Rao, GN | 1 |
| Russfield, A | 1 |
| Seilkop, S | 1 |
| Braun, AG | 1 |
| Tutton, PJ | 1 |
| Barkla, DH | 1 |
| Allen, CN | 1 |
| Harpur, ES | 1 |
| Gray, TJ | 1 |
| Simmons, NL | 1 |
| Hirst, BH | 1 |
| Levy, HA | 1 |
| Park, CH | 1 |
| Soost, HJ | 1 |
| Ries, P | 1 |
10 other studies available for reserpine and Adenocarcinoma
| Article | Year |
|---|---|
Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells.
Topics: Adenocarcinoma; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Blotting, No | 1996 |
Importance of vesicle proteins in the diagnosis and treatment of neuroendocrine tumors.
Topics: 3-Iodobenzylguanidine; Adenocarcinoma; Adrenal Gland Neoplasms; Adrenergic Uptake Inhibitors; Biopsy | 2004 |
Identification of BCRP as transporter of benzo[a]pyrene conjugates metabolically formed in Caco-2 cells and its induction by Ah-receptor agonists.
Topics: Adenocarcinoma; Anticarcinogenic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; AT | 2005 |
Radioprotection of normal and malignant tissue in the mouse by diethylaminoreserpine.
Topics: Adenocarcinoma; Animals; Antihypertensive Agents; Cell Survival; Fibrosarcoma; Hematopoietic Stem Ce | 1981 |
Chemical effects in transgenic mice bearing oncogenes expressed in mammary tissue.
Topics: Adenocarcinoma; Aniline Compounds; Animals; Carcinogens; Female; Gene Expression; Genes, myc; Genes, | 1993 |
A comparison of cell proliferation in normal and neoplastic intestinal epithelia following either biogenic amine depletion or monoamine oxidase inhibition.
Topics: Adenocarcinoma; Animals; Biogenic Amines; Cell Division; Colon; Colonic Neoplasms; Dimethylhydrazine | 1976 |
Efflux of bis-carboxyethyl-carboxyfluorescein (BCECF) by a novel ATP-dependent transport mechanism in epithelial cells.
Topics: Adenocarcinoma; Adenosine Triphosphate; Animals; Cell Line; Epithelium; Fluoresceins; Fluorescent Dy | 1990 |
Effect of reserpine on salivary gland radioiodine uptake in thyroid cancer.
Topics: Adenocarcinoma; Carcinoma, Papillary; Humans; Iodine Radioisotopes; Parotid Gland; Radiation Injurie | 1987 |
Factors influencing the toxicity of diethylaminoethylreserpine to tumor cells: studies with four transplantable tumors.
Topics: Adenocarcinoma; Aerobiosis; Animals; Carcinoma; Female; Fibrosarcoma; Lung Neoplasms; Male; Mice; Mi | 1987 |
[Secretion and hemorrhage from the breast. Causes and cytodiagnosis].
Topics: Adenocarcinoma; Adenofibroma; Adolescent; Adult; Aged; Amenorrhea; Breast; Breast Diseases; Breast N | 1969 |