reserpine has been researched along with Acute Liver Injury, Drug-Induced in 25 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Reserpine was uneffective in terms of liver derangement, but exerted some protection against the general toxic effect of A." | 1.25 | Effects of sympatholytic agents on amanita phalloides toxicity in the rat. ( Baccino, FM; Pernigotti, L; Torrielli, MV; Zuretti, MF, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (72.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (24.00) | 24.3611 |
| 2020's | 1 (4.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Morgan, RE | 2 |
| Trauner, M | 1 |
| van Staden, CJ | 2 |
| Lee, PH | 1 |
| Ramachandran, B | 1 |
| Eschenberg, M | 1 |
| Afshari, CA | 2 |
| Qualls, CW | 1 |
| Lightfoot-Dunn, R | 1 |
| Hamadeh, HK | 2 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 2 |
| Warner, DJ | 1 |
| Chen, H | 1 |
| Cantin, LD | 1 |
| Kenna, JG | 1 |
| Stahl, S | 1 |
| Walker, CL | 1 |
| Noeske, T | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Chen, M | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Norman, BH | 1 |
| LACASSAGNE, A | 1 |
| HURST, L | 1 |
| HARVEY, P | 1 |
| HAEFNER, H | 1 |
| KUTSCHER, I | 1 |
| SCHEDIFKA, R | 1 |
| HEIMBERG, M | 1 |
| WATKINS, ML | 1 |
| TOOKER, R | 1 |
| MORIN, Y | 1 |
| TURMEL, L | 1 |
| FORTIER, J | 1 |
| MOECKEL, W | 1 |
| PETZOLD, H | 1 |
| ZIMMERMANN, S | 1 |
| AMER, S | 1 |
| Nagler, A | 1 |
| Enat, R | 1 |
| Zuretti, MF | 1 |
| Pernigotti, L | 1 |
| Torrielli, MV | 1 |
| Baccino, FM | 1 |
| Schweitzer, IL | 1 |
| Peters, RL | 1 |
| Ruckebusch, Y | 1 |
| Grivel, ML | 1 |
| Sun, DC | 1 |
| Greene, NM | 1 |
| Kehoe, MJ | 1 |
| Winborn, WB | 1 |
| Seelig, LL | 1 |
| Clower, BR | 1 |
| Douglas, BH | 1 |
| Carrier, O | 1 |
| Garay, EA | 1 |
| Campa, JP | 1 |
6 reviews available for reserpine and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
Drug Induced Liver Injury (DILI). Mechanisms and Medicinal Chemistry Avoidance/Mitigation Strategies.
Topics: Animals; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Drug Discovery; Drug Eval | 2020 |
[COMPLICATIONS DURING CLINICAL THERAPY WITH PSYCHOPHARMACA].
Topics: Agranulocytosis; Autonomic Nervous System Diseases; Chemical and Drug Induced Liver Injury; Chlorpro | 1964 |
[APROPOS OF LIVER DAMAGE DUE TO PROLONGED BARBITURATE AND HYDANTOIN THERAPY].
Topics: Anticonvulsants; Barbiturates; Chemical and Drug Induced Liver Injury; Chlorpromazine; Hepatitis A; | 1964 |
Halothane anesthesia and hepatitis in a high-risk population.
Topics: Chemical and Drug Induced Liver Injury; Chlorpromazine; Diazepam; Enzyme Induction; Halothane; Human | 1973 |
II. Major tranquilizers.
Topics: Animals; Chemical and Drug Induced Liver Injury; Chlordiazepoxide; Chlorpromazine; Fluphenazine; Hem | 1971 |
19 other studies available for reserpine and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2010 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
[INFLUENCE OF SIMULTANEOUS ADMINISTRATION OF RESERPINE AND A CORTICOID ON CARCINOGENESIS OF RAT LIVER BY P-DIMETHYLAMINOAZOBENZENE (DAB)].
Topics: Adenoma, Bile Duct; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Carcinogenesis; Chemical and Drug | 1963 |
DRUG REACTIONS INVOLVING THE ALIMENTARY TRACT.
Topics: Anticoagulants; Bismuth; Chemical and Drug Induced Liver Injury; Chlorothiazide; Drug Therapy; Esoph | 1964 |
CARBON TETRACHLORIDE HEPATOTOXICITY: THE DIRECT ACTION OF CCL4 ON THE LIVER.
Topics: Bile; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; | 1964 |
METHYLDOPA: CLINICAL STUDIES IN ARTERIAL HYPERTENSION.
Topics: Cardiac Output; Chemical and Drug Induced Liver Injury; Drug Therapy; Hemodynamics; Hepatitis; Human | 1964 |
[ON THE CLINICAL PICTURE OF JAUNDICE WITH INTRAHEPATIC CHOLESTASIS CAUSED BY DRUGS].
Topics: Biliary Dyskinesia; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Drug Hypersen | 1965 |
[THE EFFECT OF DIFFERENT SUBSTANCES ON ACUTE CARBON TETRACHLORIDE NECROSIS OF THE RAT LIVER].
Topics: Aspartate Aminotransferases; Blood Chemical Analysis; Carbon Tetrachloride; Carbon Tetrachloride Poi | 1965 |
[Liver damage due to reserpine hypersensitivity].
Topics: Chemical and Drug Induced Liver Injury; Dihydralazine; Drug Hypersensitivity; Drug Therapy, Combinat | 1984 |
Effects of sympatholytic agents on amanita phalloides toxicity in the rat.
Topics: Acid Phosphatase; Animals; Butoxamine; Catecholamines; Chemical and Drug Induced Liver Injury; Epine | 1975 |
Acute submassive hepatic necrosis due to methyldopa. A case demonstrating possible initiation of chronic liver disease.
Topics: Alanine Transaminase; Aspartate Aminotransferases; Biopsy, Needle; Chemical and Drug Induced Liver I | 1974 |
[Hepatic insufficiency and neurotropic medicinal activity].
Topics: Animals; Chemical and Drug Induced Liver Injury; Dogs; Drug Synergism; Female; Hexobarbital; Ipronia | 1966 |
Iatrogenic gastrointestinal diseases in the aged.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aged; Cathartics; Chemical and Drug Induced Li | 1972 |
Cytologic effects of reserpine on hepatocytes. An ultrastructural study of drug toxicity.
Topics: Animals; Body Weight; Chemical and Drug Induced Liver Injury; Cricetinae; Cytoplasm; Endoplasmic Ret | 1970 |
Protection by reserpine of carbon tetrachloride-induced hepatic necrosis.
Topics: Animals; Calcium; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Female; Histocytoche | 1968 |
Bilirubin metabolism in experimental liver injury.
Topics: Animals; Bile; Bilirubin; Blood Volume Determination; Carbon Isotopes; Carbon Tetrachloride Poisonin | 1968 |