reserpine has been researched along with Abnormalities, Autosome in 4 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Reserpine, which was negative in an in vitro chromosome aberration test, was administered intraperitoneally at 1, 5, 10, 100, and 1000 mg/kg to mice to induce hypothermia." | 1.30 | Hypothermia induces micronuclei in mouse bone marrow cells. ( Asanami, S; Shimono, K, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tsutsui, T | 1 |
| Taguchi, S | 1 |
| Hasegawa, K | 1 |
| Ide, T | 1 |
| Kojima, K | 1 |
| Matsumura, M | 1 |
| Huff, J | 1 |
| Barrett, JC | 1 |
| Asanami, S | 1 |
| Shimono, K | 1 |
| Subramanyam, S | 1 |
4 other studies available for reserpine and Abnormalities, Autosome
| Article | Year |
|---|---|
Reserpine-induced cell transformation without detectable genetic effects in Syrian hamster embryo cells in culture.
Topics: Aneuploidy; Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; C | 1994 |
Hypothermia induces micronuclei in mouse bone marrow cells.
Topics: Animals; Body Temperature; Bone Marrow Cells; Chromosome Aberrations; Hypothermia; In Vitro Techniqu | 1997 |
Cytogenetic action of the antihypertensive agent adelphane on meiotic cells of Poekilocerus pictus.
Topics: Animals; Antihypertensive Agents; Chromatids; Chromosome Aberrations; Dihydralazine; Drug Combinatio | 1979 |
Evaluation of drugs and other chemical agents for teratogenicity.
Topics: Abnormalities, Drug-Induced; Adrenal Cortex Hormones; Animals; Cats; Chromosome Aberrations; Chromos | 1974 |