reserpine has been researched along with Abnormal Movements in 6 studies
Reserpine: An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.
reserpine : An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Agmatine is an endogenous arginine metabolite that emerges as neuromodulator and a promising agent to manage diverse central nervous system disorders by modulating nitric oxide (NO) pathway, glutamate NMDA receptors and oxidative stress." | 1.43 | Agmatine attenuates reserpine-induced oral dyskinesia in mice: Role of oxidative stress, nitric oxide and glutamate NMDA receptors. ( Blum-Silva, CH; Colle, D; Cunha, AS; Cunha, MP; Farina, M; Matheus, FC; Moretti, M; Poli, A; Prediger, RD; Reginatto, FH; Rodrigues, AL; Sampaio, TB; Sandjo, LP; Santos, DB, 2016) |
| "Reserpine-induced orofacial dyskinesia is a model that shares some mechanists' aspects with tardive dyskinesia whose pathophysiology has been related to oxidative stress." | 1.39 | Protective effect of nebivolol on reserpine-induced neurobehavioral and biochemical alterations in rats. ( Kawale, LA; Khatri, ML; Nade, VS; Patil, NR; Shendye, NV, 2013) |
| "In reserpine-treated animals, specific delta opioid binding was increased in premotor cortex (+30%), sensorimotor striatum (+20%), and associative striatum (+17%) rostrally, but was not changed in caudal forebrain." | 1.34 | Striatal delta opioid receptor binding in experimental models of Parkinson's disease and dyskinesia. ( Brotchie, JM; Hallett, PJ, 2007) |
| "Ropinirole was weakly neuroprotective in this model." | 1.32 | S32504, a novel naphtoxazine agonist at dopamine D3/D2 receptors: II. Actions in rodent, primate, and cellular models of antiparkinsonian activity in comparison to ropinirole. ( Brocco, M; Brotchie, J; Crossman, A; Di Cara, B; Gobert, A; Hill, M; Jackson, M; Jenner, P; Joyce, JN; McGuire, S; Millan, MJ; Peglion, JL; Smith, L, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Soung, HS | 1 |
| Wang, MH | 1 |
| Chang, KC | 1 |
| Chen, CN | 1 |
| Chang, Y | 1 |
| Yang, CC | 1 |
| Tseng, HC | 1 |
| Nade, VS | 1 |
| Shendye, NV | 1 |
| Kawale, LA | 1 |
| Patil, NR | 1 |
| Khatri, ML | 1 |
| Cunha, AS | 1 |
| Matheus, FC | 1 |
| Moretti, M | 1 |
| Sampaio, TB | 1 |
| Poli, A | 1 |
| Santos, DB | 1 |
| Colle, D | 1 |
| Cunha, MP | 1 |
| Blum-Silva, CH | 1 |
| Sandjo, LP | 1 |
| Reginatto, FH | 1 |
| Rodrigues, AL | 1 |
| Farina, M | 1 |
| Prediger, RD | 1 |
| CIMELLARO, M | 1 |
| FERRARI, B | 1 |
| Millan, MJ | 1 |
| Di Cara, B | 1 |
| Hill, M | 1 |
| Jackson, M | 1 |
| Joyce, JN | 1 |
| Brotchie, J | 1 |
| McGuire, S | 1 |
| Crossman, A | 1 |
| Smith, L | 1 |
| Jenner, P | 1 |
| Gobert, A | 1 |
| Peglion, JL | 1 |
| Brocco, M | 1 |
| Hallett, PJ | 1 |
| Brotchie, JM | 1 |
1 review available for reserpine and Abnormal Movements
| Article | Year |
|---|---|
[CONTRIBUTION TO THE STUDY OF UTERINE DYSKINESIAS AND THEIR TREATMENT].
Topics: Adenosine Triphosphate; Dyskinesias; Dystocia; Ergotamine; Female; Hexoses; Humans; Insulin; Meperid | 1963 |
5 other studies available for reserpine and Abnormal Movements
| Article | Year |
|---|---|
Topics: Analysis of Variance; Animals; Antipsychotic Agents; Caspase 3; Cytokines; Disease Models, Animal; D | 2018 |
Protective effect of nebivolol on reserpine-induced neurobehavioral and biochemical alterations in rats.
Topics: Animals; Antihypertensive Agents; Behavior, Animal; Benzopyrans; Brain; Dyskinesias; Ethanolamines; | 2013 |
Agmatine attenuates reserpine-induced oral dyskinesia in mice: Role of oxidative stress, nitric oxide and glutamate NMDA receptors.
Topics: Agmatine; Animals; Cerebral Cortex; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Do | 2016 |
S32504, a novel naphtoxazine agonist at dopamine D3/D2 receptors: II. Actions in rodent, primate, and cellular models of antiparkinsonian activity in comparison to ropinirole.
Topics: Acetylcholine; Animals; Callithrix; Cells, Cultured; Disease Models, Animal; Dopamine Agonists; Dopa | 2004 |
Striatal delta opioid receptor binding in experimental models of Parkinson's disease and dyskinesia.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Analysis of Variance; Animals; Corpus Striatum; Diseas | 2007 |