Page last updated: 2024-09-05

repinotan hydrochloride and Cerebral Ischemia

repinotan hydrochloride has been researched along with Cerebral Ischemia in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, S; Fierus, M; Hacke, W; Kaste, M; Lyden, PD; Teal, P1
Lutsep, HL1
Krieglstein, J; Semkova, I; Wolz, P1
Alessandri, B; Bullock, RM; Tsuchida, E1
Fahrig, T; Horváth, E; Jork, R; Mauler, F1

Reviews

1 review(s) available for repinotan hydrochloride and Cerebral Ischemia

ArticleYear
Repinotan, A 5-HT1A agonist, in the treatment of acute ischemic stroke.
    Current drug targets. CNS and neurological disorders, 2005, Volume: 4, Issue:2

    Topics: Acute Disease; Aged; Benzopyrans; Brain Ischemia; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Neuroprotective Agents; Serotonin Receptor Agonists; Stroke; Thiazoles; Treatment Outcome

2005

Trials

1 trial(s) available for repinotan hydrochloride and Cerebral Ischemia

ArticleYear
A randomized, double-blind, placebo-controlled trial to evaluate the efficacy, safety, tolerability, and pharmacokinetic/pharmacodynamic effects of a targeted exposure of intravenous repinotan in patients with acute ischemic stroke: modified Randomized Ex
    Stroke, 2009, Volume: 40, Issue:11

    Topics: Aged; Aged, 80 and over; Benzopyrans; Brain Ischemia; Dose-Response Relationship, Drug; Double-Blind Method; Drug Delivery Systems; Female; Humans; Infusions, Intravenous; Internationality; Male; Middle Aged; Stroke; Thiazoles

2009

Other Studies

3 other study(ies) available for repinotan hydrochloride and Cerebral Ischemia

ArticleYear
Neuroprotective effect of 5-HT1A receptor agonist, Bay X 3702, demonstrated in vitro and in vivo.
    European journal of pharmacology, 1998, Oct-23, Volume: 359, Issue:2-3

    Topics: Animals; Benzopyrans; Brain; Brain Ischemia; Cell Death; Cell Survival; Cells, Cultured; Cerebral Infarction; Disease Models, Animal; Dose-Response Relationship, Drug; Glutamic Acid; Hippocampus; Male; Neurons; Rats; Rats, Inbred F344; Rats, Long-Evans; Serotonin Receptor Agonists; Thiazoles

1998
The neuroprotective effect of a new serotonin receptor agonist, BAY X3702, upon focal ischemic brain damage caused by acute subdural hematoma in the rat.
    Brain research, 1999, Oct-23, Volume: 845, Issue:2

    Topics: Animals; Benzopyrans; Brain Ischemia; Dose-Response Relationship, Drug; Hematoma, Subdural, Acute; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Thiazoles

1999
Inhibition of evoked glutamate release by the neuroprotective 5-HT(1A) receptor agonist BAY x 3702 in vitro and in vivo.
    Brain research, 2001, Jan-05, Volume: 888, Issue:1

    Topics: Animals; Aspartic Acid; Benzopyrans; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Space; Glutamic Acid; Hippocampus; Infarction, Middle Cerebral Artery; Male; Microdialysis; Neuroprotective Agents; Organ Culture Techniques; Rats; Rats, Wistar; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Synaptic Transmission; Thiazoles

2001