remifentanil has been researched along with Allodynia in 159 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 33 (20.75) | 29.6817 |
| 2010's | 96 (60.38) | 24.3611 |
| 2020's | 30 (18.87) | 2.80 |
| Authors | Studies |
|---|---|
| Aceto, P; Cappoli, N; Dello Russo, C; Mezzogori, D; Navarra, P; Sollazzi, L; Tabolacci, E | 1 |
| Bai, X; Dong, B; Niu, T; Su, L; Wang, G; Yu, Y; Zhuang, X | 1 |
| Bauer, M; Bessiere, B; Ihmsen, H; Noel, N; Prottengeier, J; Ramirez-Gil, JF; Schüttler, J; Wehrfritz, A | 1 |
| Gao, T; Li, J; Li, Y; Wang, C; Wang, G; Zhang, H; Zhang, L; Zhao, Y | 1 |
| Dieterle, M; Frei, P; Mauermann, E; Mercer-Chalmers-Bender, K; Ruppen, W; Schneider, T; Zurbriggen, L | 1 |
| Ma, F; Zhang, T | 1 |
| Dong, B; Shen, M; Wang, C; Xie, K; Yu, Y; Yuan, Y; Zhao, Y | 1 |
| Bae, H; Kim, JT; Kim, Y; Lim, YJ; Park, SK; Sakura, S; Yoo, S | 1 |
| Hirota, K; Lambert, DG | 1 |
| Magoon, R | 1 |
| Gao, L; Wang, C; Wu, Z; Xu, H; Yao, Y; Zheng, F; Zhou, J | 1 |
| Todorovic, SM | 1 |
| Chen, D; Chen, L; Gu, E; Hu, R; Jia, C; Jin, Y; Liu, X; Mao, Y; Tai, Y; Tao, W; Yang, CL; Zhang, Z; Zhou, J | 1 |
| Gao, Y; Li, J; Li, Q; Li, Y; Ma, W; Sun, Z; Wang, C; Wang, Q; Yu, Y | 1 |
| Abdul Razak, N; Chan, CYW; Chiu, CK; Hasan, MS; Kwan, MK; Lee, ZY; Ng, CC; Yip, HW; Yunus, SN | 1 |
| Chen, J; Chen, Y; Duan, G; He, J; Huang, H; Ju, D; Liu, H; Shu, B; Tian, H; Wu, Y; Zheng, X | 1 |
| Qiang, Z; Yu, W | 1 |
| Chen, L; Chen, Z; Gao, X; Li, Z; Lin, C; Liu, T; Qi, F; Tang, H; Wang, L; Wang, ZJ; Zhang, X | 1 |
| Hong, HK; Ma, Y; Xie, H | 1 |
| Chai, X; Gao, C; Li, T; Shu, S; Xie, Y | 1 |
| Su, X; Tan, L; Tian, Y; Wu, H; Wu, L; Zhu, W | 1 |
| Chen, Z; Hu, Z; Li, Z; Qi, F; Tang, H; Wang, ZJ; Zhang, L; Zhou, J | 1 |
| Domínguez, JM; Fernández-Sarmiento, JA; Gómez-Villamandos, RJ; Granados, MM; Morgaz, J; Muñoz-Rascón, P; Navarrete-Calvo, R; Quirós-Carmona, S; Ruíz-López, P | 1 |
| Jia, Z; Li, Q; Li, Y; Su, L; Wang, C; Xu, R; Yu, Y; Zhang, H; Zhao, Q | 1 |
| Cui, W; Li, Y; Liu, P; Song, C; Tao, Y; Wang, C; Wang, G; Wang, Z; Xie, K; Zhang, L | 1 |
| Li, Y; Shu, R; Su, L; Wang, C; Wang, G; Zhang, H; Zhang, L; Zhao, H | 1 |
| Cao, L; Li, H; Lin, Q; Lin, W; Tan, H; Wu, Z; Yu, J; Zhang, T | 1 |
| Amaya, F; Horii, Y; Ishikawa, D; Matsuda, M; Sawa, T; Takemura, H | 1 |
| Dunn, LK; Grant, MC | 1 |
| Ding, R; Fu, R; Gong, X; Li, S; Li, Y; Wang, Y; Zhang, L; Zhou, G; Zhu, Z | 1 |
| Chen, Y; Li, J; Li, Y; Wang, C; Wang, G; Xie, K; Yu, Y; Yuan, Y; Zhang, L | 1 |
| Bai, X; Dong, B; Li, Y; Niu, T; Su, L; Wang, G; Yu, Y; Zhuang, X | 1 |
| Jia, LL; Sun, Y; Yu, WL; Yuan, ST; Zhu, M | 1 |
| Cho, YJ; Jeon, Y; Kim, BR; Kim, TK; Koo, CH; Seo, JH; Yoon, S | 1 |
| Chen, JP; Wu, GR; Ye, HW; Zhang, HF | 1 |
| Arcioni, R; D'Andrilli, A; De Blasi, RA; Massullo, D; Mercieri, M; Naccarato, A; Palmisani, S; Rocco, M; Silvestri, B; Tigano, S | 1 |
| Lai, L; Lei, H; Li, L; Liang, W; Lu, A; Xu, S | 1 |
| Aguado, D; Bustamante, R; Gómez de Segura, IA | 1 |
| Guo, S; Li, Y; Song, C; Wang, C; Wang, G; Yu, Y; Zhang, L; Zhao, Q | 1 |
| Huang, G; Li, S; Yu, C; Zeng, J; Zhang, C | 1 |
| Barry, N; Beebe, AC; Bhalla, T; Gill, L; Klamar, J; Martin, DP; Rice, J; Samora, WP; Thung, A; Tobias, JD; Tumin, D; Veneziano, G | 1 |
| Daeter, EJ; Dahan, A; de Hoogd, S; Knibbe, CAJ; Tibboel, D; Valkenburg, AJ; van Dongen, EPA; van Rosmalen, J | 1 |
| Chen, F; Jiang, LS; Lv, CC; Shu, SJ; Xia, ML | 1 |
| Cai, J; Cui, YJ; Liu, LY; Xing, GG; Zhao, HY | 1 |
| Ni, K; Peng, Y; Zang, T; Zhou, L; Zhou, X | 1 |
| Ahn, S; Gecelter, R; Kars, MS; Merwin, S; Poon, S; Rothman, A; Villacres Mori, B; Wendolowski, S | 1 |
| An, XJ; Chen, JP; Hu, XK; Liu, RJ; Wu, GR; Yang, J | 1 |
| Hu, J; Qing, W; Yan, J; Zhai, Z; Zhang, C; Zhang, J | 1 |
| Abreu, M; Aguado, D; Benito, J; Garcia-Fernandez, J; Gómez de Segura, IA | 3 |
| Baba, H; Ishii, H; Kohno, T; Petrenko, AB | 1 |
| Han, S; Li, J; Li, S; Peng, Z; Wang, Q; Zhao, X | 1 |
| Lu, B; Sun, JL; Xiao, C; Yao, J | 1 |
| Harnischmacher, U; Junghaenel, S; Link, F; Oberthuer, A; Roth, B; Stuetzer, H; Welzing, L | 1 |
| Aksionova, D; Brimas, G; Cincilevičiūtė, G; Kontrimavičiūtė, E; Sipylaitė, J | 1 |
| Li, Y; Wang, C; Wang, G; Wang, H; Xie, K; Yang, Z; Yu, Y | 1 |
| Abou Zeid, HA; Ghanem, IB; Jabbour, HJ; Jabbour, KB; Jawish, RJ; Naccache, NM; Rabbaa-Khabbaz, LG; Yazbeck, PH | 1 |
| Gu, X; Liu, X; Liu, Y; Ma, Z; Sun, Y; Zhang, W | 1 |
| Buckley, MS; Coons, JC; Kane-Gill, SL; Rice, MJ; Rivosecchi, RM; Smithburger, PL | 1 |
| Jiang, LS; Peng, YN; Tang, LH; Xia, WS; Yan, M; Yu, LN; Zhang, FJ; Zhou, XL | 1 |
| Gu, X; Liu, X; Liu, Y; Ma, Z; Sun, YE; Zhang, J; Zhang, W | 1 |
| Fletcher, D; Martinez, V | 1 |
| Li, N; Shu, R; Wang, C; Wang, G; Wang, H; Zhang, L | 1 |
| Hu, N; Li, YZ; Tang, XH; Wang, CY; Wang, GL; Wang, HY; Xie, KL; Yu, YH | 1 |
| Shu, R; Wang, C; Wang, G; Wang, H; Wang, M; Yang, M; Yu, Y; Zhang, L | 1 |
| Gu, X; He, J; Kong, M; Ma, Z; Shi, L; Zhang, J; Zhang, W; Zhou, Y | 1 |
| Bilgin, R; Kilinc, M; Mert, T; Oksuz, H; Senoglu, N; Tugtag, B | 1 |
| Abreu, M; Aguado, D; Benito, J; García-Fernández, J; Segura, IA | 1 |
| Hu, N; Li, Y; Shu, R; Wang, C; Wang, G; Wang, H; Xie, K; Yu, Y; Zhang, L | 1 |
| Li, N; Shu, RC; Wang, CY; Wang, GL; Wang, HY; Xie, KL; Yu, YH; Zhang, LL | 1 |
| Curry, RS; Eisenach, JC; Tong, C | 1 |
| Cui, W; Han, R; Li, J; Wang, Q; Wang, S | 1 |
| Gu, X; He, J; Kong, M; Liu, Y; Lu, C; Ma, Z; Shi, L; Xu, L; Zhang, J; Zhou, Y | 1 |
| Li, SS; Yu, C; Zhang, C; Zhao, N | 1 |
| Brunialti, MK; Leal, PC; Sakata, RK; Salomão, R | 1 |
| Cheng, C; Gu, X; Jiang, M; Ma, Z; Zhang, W | 1 |
| Angst, MS | 1 |
| Filitz, J; Koppert, W; Maihöfner, C; Möhringer, S; Münster, T; Nickel, FT; Ott, S; Rieß, S | 1 |
| Ding, L; Li, N; Shu, R; Wang, G; Wang, H; Wang, Z; Yu, Y; Zhang, L | 1 |
| Wang, Y; Xu, GM; Yang, LH | 1 |
| Choi, SS; Jo, JY; Joo, EY; Karm, MH; Kim, JH; Ku, S; Park, SU; Sim, JH; Yi, JM | 1 |
| Comelon, M; Draegni, T; Lenz, H; Nielsen, CS; Raeder, J; Stubhaug, A | 1 |
| Apiou-Sbirlea, G; Bessiere, B; Noel, N; Richebé, P; Schaefer, S; Schuettler, J; Simonnet, G; Troester, A; Wehrfritz, A | 1 |
| Astuto, M; Bernardini, R; Conticello, C; Gullo, A; Minardi, C; Palermo, F; Sanfilippo, F; Santonocito, C | 1 |
| Shu, R; Wang, C; Wang, G; Wang, H; Yu, Y; Zhang, L; Zhao, Q | 1 |
| Li, Y; Shu, R; Wang, C; Wang, G; Wang, H; Yu, Y; Zhang, L; Zhao, Q | 1 |
| Ao, J; Guo, S; Li, N; Tang, X; Wang, G; Wang, Z; Xie, K; Yuan, Y; Zhang, L; Zhang, Y | 1 |
| Ansong, E; Dong, J; Feng, X; Lin, H; Sun, J; Xu, X | 1 |
| Gong, G; Hu, L; Qin, F; Wu, W; Yi, X; Yin, L; Yuan, L | 1 |
| Bai, X; Chen, Y; Cui, Y; Li, Y; Xiao, L; Yang, SY; Ye, L | 1 |
| Cheng, Y; Guo, R; Kong, M; Li, J; Wu, Z; Yang, L; Zhong, Z | 1 |
| Chen, G; Deng, L; Song, F; Zhang, L; Zhao, H; Zhu, H | 1 |
| Irwin, MG; Lam, SW; Tran, DH; Yu, EH | 1 |
| Cho, YJ; Hong, DM; Jeon, Y; Kim, TK; Koo, CH | 1 |
| Chen, Y; Cui, Y; Duan, JJ; Xiao, L; Yang, SY; Ye, L | 1 |
| Li, Y; Shu, R; Wang, G; Yu, Y; Zhang, L; Zhao, Q | 1 |
| Fang, H; Yang, M; Zhang, F; Zhang, J | 1 |
| Chen, Y; He, Y; Sun, Z; Wang, GL; Wang, Z; Xie, KL; Yu, YH; Yuan, Y; Zheng, Y | 1 |
| Gu, X; Liu, Y; Ma, Z; Ni, Y; Sun, YE; Zhang, W | 1 |
| He, G; Lin, H; Lin, W; Sun, J; Yang, J | 1 |
| Joo, DT; Zhao, M | 1 |
| Ahier, J; Crawford, MW; Hull, R; McDonnell, C; Pehora, C; Thalayasingam, P; Zaarour, C | 1 |
| Ben-David, B; Chelly, JE | 1 |
| Imai, Y; Kitamura, T; Muroya, M; Ogawa, M; Ohno, N; Yamada, Y | 1 |
| Drdla, R; Gassner, M; Gingl, E; Sandkühler, J | 1 |
| Cabañero, D; Campillo, A; Célérier, E; Puig, MM; Romero, A | 1 |
| Cui, W; Han, S; Jiang, J; Li, J; Li, S; Li, Y; Yang, W | 1 |
| Cui, S; Gu, X; Liu, Y; Ma, Z; Wu, X | 1 |
| Freye, E; Levy, JV | 1 |
| Alper, Y; Reisli, R; Tuncer, S; Yalçin, N | 1 |
| Angst, MS; Chu, LF; Dairmont, J; Young, CA; Zamora, AK | 1 |
| Byeon, GJ; Cho, AR; Kim, HJ; Kim, KH; Kwon, JY; Lee, HJ; Shin, SW; Yoon, JW | 1 |
| Konopka, KH; van Wijhe, M | 1 |
| Cabañero, D; Campillo, A; García-Nogales, P; Puig, MM; Romero, A | 1 |
| Draegni, T; Heyerdahl, F; Lenz, H; Raeder, J; Schmelz, M; Stubhaug, A | 1 |
| Gu, YP; Hang, LH; Shao, DH | 1 |
| Kager, HI; Likar, R; Ohner, C; Pipam, W; Schlimp, CJ; Wolrab, C | 1 |
| Lee, YW; Park, SJ; Shim, YH; Song, JW; Yoon, KB | 1 |
| Hu, SJ; Huang, ZL; Li, J; Lian, QQ; Ma, JF | 1 |
| Cahana, A; Calderon, J; Janvier, G; Jelacic, S; Mehta, S; Picard, W; Pouquet, O; Richebé, P; Rivat, C | 1 |
| Bugedo, D; Cortínez, LI; Echevarría, G; Elgueta, F; Faba, G; Fierro, C; Iñiguez-Cuadra, R; Muñoz, HR | 1 |
| Hashimoto, T; Ishida, R; Nikai, T; Saito, Y; Tsumori, T | 1 |
| Campillo, A; González-Cuello, A; Laorden, ML; Puig, MM; Romero, A; Romero-Alejo, E; Vasconcelos, N | 1 |
| Benrath, J; Drdla-Schutting, R; Sandkühler, J; Wunderbaldinger, G | 1 |
| Cui, S; Gu, X; Liu, Y; Ma, Z; Zhang, J; Zhang, W; Zheng, Y | 1 |
| Angst, MS; Chu, LF; Clark, DJ; Cun, T; Kim, JE; Ngai, LK; Young, CA; Zamora, AK | 1 |
| Werner, MU | 1 |
| Akarsu, M; Otelcioğlu, S; Reisli, R; Tuncer, S | 1 |
| Wang, GL; Wang, JY; Yu, YH; Yuan, F; Yuan, Y | 1 |
| Coghill, RC; Eisenach, JC; Martucci, KT; Tong, C | 1 |
| Borazan, H; Otelcioglu, S; Reisli, R; Uzun, ST; Yalcin, N | 1 |
| Ihmsen, H; Manering, NA; Reuter, T; Tzabazis, A; Yeomans, DC | 1 |
| Wang, GL; Wang, JY; Xie, KL; Yu, YH; Yuan, F; Yuan, Y | 1 |
| Puig, MM; Romero, A; Romero-Alejo, E; Vasconcelos, N | 1 |
| Dahl, JB; Dirks, J; Hilsted, KL; Møiniche, S | 1 |
| Arendt-Nielsen, L; Curatolo, M; Gerber, A; Luginbühl, M; Petersen-Felix, S; Schnider, TW | 1 |
| Angst, MS; Lötsch, J | 1 |
| Alsheimer, M; Koppert, W; Scheuber, K; Schmelz, M; Schüttler, J; Sittl, R | 1 |
| Curry, R; Eisenach, JC; Hood, DD | 1 |
| Angst, MS; Clark, DJ; Koppert, W; Pahl, I; Schmelz, M | 1 |
| Albrecht, S; Alsheimer, M; Angst, M; Koppert, W; Schmelz, M; Schüttler, J; Sittl, R | 1 |
| Dahl, JB; Hoke, F; Maloney, A; Petersen, KL; Rowbotham, MC | 1 |
| Felouzis, E; Gustorff, B; Hoechtl, K; Kress, HG; Lehr, S; Sycha, T | 1 |
| Bonnet, F; Chaaben, K; Lamonerie, L; Lembert, N; Marret, E | 1 |
| Chauvin, M; Fletcher, D; Guignard, B; Joly, V; Maurette, P; Richebe, P; Sessler, DI | 1 |
| Bardin, L; Colpaert, FC; Degryse, AD; Gomez de Segura, IA; Kiss, I | 1 |
| Li, Y; Luo, YL; Xiao, SS; Yu, C; Zhang, Q | 1 |
| Angst, MS; Chu, LF; Clark, DJ | 1 |
| Cabañero, D; Célérier, E; González, JR; Maldonado, R; Puig, MM | 1 |
| Dumont, H; Guntz, E; Roman, A; Segers, B; Sosnowski, M; Talla, G | 1 |
| Koppert, W; Schmelz, M; Schüttler, J; Singler, B; Sittl, R; Tröster, A | 1 |
| Koppert, W; Manering, N; Schüttler, J; Singler, B; Tröster, A | 1 |
| Schäfer, M; Zöllner, C | 1 |
| Koppert, W; Tzabazis, AZ | 1 |
| Hoymork, SC; Lenz, H; Raeder, J | 1 |
| Cortiñas Sáenz, M; Cortiñas Sáenz, ML; Gerónimo Pardo, M; Hernández Vallecillo, MT; Ibarra Martí, ML; Mateo Cerdán, CM | 1 |
| Dahl, JB; Jones, B; Petersen, KL; Rowbotham, MC; Segredo, V | 1 |
| Nozaki-Taguchi, N; Yaksh, TL | 1 |
6 review(s) available for remifentanil and Allodynia
| Article | Year |
|---|---|
Ketamine; history and role in anesthetic pharmacology.
Topics: Analgesics, Opioid; Anesthetics; Humans; Hyperalgesia; Ketamine; Phencyclidine; Remifentanil | 2022 |
An evidence based systematic review of remifentanil associated opioid-induced hyperalgesia.
Topics: Analgesics; Analgesics, Opioid; Evidence-Based Medicine; Humans; Hyperalgesia; Piperidines; Remifentanil | 2014 |
Opioid-induced hyperalgesia in patients after surgery: a systematic review and a meta-analysis.
Topics: Analgesics, Opioid; Dose-Response Relationship, Drug; Humans; Hyperalgesia; Pain Measurement; Pain, Postoperative; Piperidines; Randomized Controlled Trials as Topic; Remifentanil | 2014 |
Intraoperative Use of Remifentanil for TIVA: Postoperative Pain, Acute Tolerance, and Opioid-Induced Hyperalgesia.
Topics: Analgesics, Opioid; Anesthetics, Inhalation; Drug Delivery Systems; Drug Tolerance; Humans; Hyperalgesia; Pain, Postoperative; Piperidines; Propofol; Remifentanil | 2015 |
Remifentanil tolerance and hyperalgesia: short-term gain, long-term pain?
Topics: Analgesics, Opioid; Drug Administration Schedule; Drug Tolerance; Humans; Hyperalgesia; Intraoperative Care; Pain, Postoperative; Piperidines; Receptors, N-Methyl-D-Aspartate; Remifentanil | 2016 |
[Remifentanil-based intraoperative anaesthesia and postoperative pain therapy. Is there an optimal treatment strategy?].
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Intravenous; Anesthetics, Intravenous; Humans; Hyperalgesia; Pain, Postoperative; Piperidines; Remifentanil; Substance Withdrawal Syndrome | 2007 |
54 trial(s) available for remifentanil and Allodynia
| Article | Year |
|---|---|
Evaluation of antihyperalgesic and analgesic effects of 35% nitrous oxide when combined with remifentanil: A randomised phase 1 trial in volunteers.
Topics: Analgesics, Opioid; Double-Blind Method; Healthy Volunteers; Humans; Hyperalgesia; Male; Nitrous Oxide; Pain, Postoperative; Piperidines; Remifentanil | 2021 |
Pain response to cannabidiol in opioid-induced hyperalgesia, acute nociceptive pain, and allodynia using a model mimicking acute pain in healthy adults in a randomized trial (CANAB II).
Topics: Acute Pain; Adult; Analgesics, Opioid; Cannabidiol; Cross-Over Studies; Double-Blind Method; Humans; Hyperalgesia; Nociceptive Pain; Piperidines; Remifentanil | 2022 |
Effect of remifentanil on post-operative analgesic consumption in patients undergoing shoulder arthroplasty after interscalene brachial plexus block: a randomized controlled trial.
Topics: Analgesics; Analgesics, Opioid; Arthroplasty, Replacement, Shoulder; Brachial Plexus Block; Delirium; Fentanyl; Humans; Hyperalgesia; Hypotension; Nefopam; Pain, Postoperative; Postoperative Nausea and Vomiting; Remifentanil | 2022 |
Regulatory effects of propofol on high-dose remifentanil-induced hyperalgesia.
Topics: Adult; Analgesics, Opioid; Anesthetics, Inhalation; Anesthetics, Intravenous; Cholecystectomy, Laparoscopic; Humans; Hyperalgesia; Middle Aged; Pain, Postoperative; Propofol; Remifentanil; Sevoflurane; Sufentanil | 2020 |
Determination of acute tolerance and hyperalgesia to remifentanil constant rate infusion in dogs undergoing sevoflurane anaesthesia.
Topics: Analgesics, Opioid; Anesthetics, Inhalation; Animals; Cross-Over Studies; Dog Diseases; Dogs; Drug Tolerance; Female; Hyperalgesia; Male; Pain Threshold; Remifentanil; Sevoflurane | 2020 |
Effects of an Intraoperative Intravenous Bolus Dose of Dexmedetomidine on Remifentanil-Induced Postinfusion Hyperalgesia in Patients Undergoing Thyroidectomy: A Double-Blind Randomized Controlled Trial.
Topics: Administration, Intravenous; Adrenergic alpha-2 Receptor Agonists; Adult; Aged; Analgesics, Opioid; China; Dexmedetomidine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hyperalgesia; Male; Middle Aged; Pain Threshold; Pain, Postoperative; Prospective Studies; Remifentanil; Thyroidectomy; Time Factors; Treatment Outcome; Young Adult | 2021 |
Intraoperative naloxone reduces remifentanil-induced postoperative hyperalgesia but not pain: a randomized controlled trial.
Topics: Adult; Aged; Analgesics, Opioid; Double-Blind Method; Female; Humans; Hyperalgesia; Intraoperative Care; Male; Middle Aged; Naloxone; Narcotic Antagonists; Pain Measurement; Pain, Postoperative; Prospective Studies; Remifentanil; Young Adult | 2017 |
[Effects of lappaconitine on intraoperative administration of remifentanil induced postoperative hyperalgesia in general anaesthesia patients].
Topics: Aconitine; Aged; Analgesics, Opioid; Anesthesia, General; Female; Humans; Hyperalgesia; Male; Middle Aged; Pain, Postoperative; Piperidines; Postoperative Complications; Remifentanil | 2017 |
Low-dose buprenorphine infusion to prevent postoperative hyperalgesia in patients undergoing major lung surgery and remifentanil infusion: a double-blind, randomized, active-controlled trial.
Topics: Aged; Analgesics, Opioid; Buprenorphine; Double-Blind Method; Female; Humans; Hyperalgesia; Infusions, Intravenous; Lung; Male; Middle Aged; Pain, Postoperative; Prospective Studies; Remifentanil | 2017 |
Analgesic effects of methadone and magnesium following posterior spinal fusion for idiopathic scoliosis in adolescents: a randomized controlled trial.
Topics: Adolescent; Analgesics, Opioid; Desflurane; Female; Humans; Hyperalgesia; Magnesium; Male; Methadone; Pain, Postoperative; Prospective Studies; Remifentanil; Scoliosis; Spinal Fusion | 2018 |
Short- and long-term impact of remifentanil on thermal detection and pain thresholds after cardiac surgery: A randomised controlled trial.
Topics: Aged; Analgesics, Opioid; Cardiac Surgical Procedures; Female; Hot Temperature; Humans; Hyperalgesia; Male; Middle Aged; Netherlands; Pain Threshold; Pain, Postoperative; Prospective Studies; Remifentanil; Single-Blind Method; Time Factors | 2019 |
[Effects of remifentanil gradual withdrawal on remifentanil induced postoperative hyperalgesia].
Topics: Adult; Analgesics, Opioid; Female; Humans; Hyperalgesia; Middle Aged; Pain, Postoperative; Piperidines; Remifentanil; Young Adult | 2019 |
[Effect of dexmedetomidine in acute postoperative pain relief is independent of suppressing the hyperalgesia induced by remifentanil].
Topics: Adult; Aged; Dexmedetomidine; Female; Humans; Hyperalgesia; Male; Middle Aged; Pain Threshold; Pain, Postoperative; Piperidines; Remifentanil | 2013 |
Remifentanil-induced tolerance, withdrawal or hyperalgesia in infants: a randomized controlled trial. RAPIP trial: remifentanil-based analgesia and sedation of paediatric intensive care patients.
Topics: Analgesia; Analgesics, Opioid; Drug Tolerance; Fentanyl; Gestational Age; Humans; Hyperalgesia; Hypnotics and Sedatives; Infant; Infant, Newborn; Infant, Newborn, Diseases; Intensive Care Units, Neonatal; Intensive Care Units, Pediatric; Piperidines; Remifentanil; Respiration, Artificial; Substance Withdrawal Syndrome | 2013 |
Comparison of different anesthetic regimens in patients undergoing laparoscopic adjustable gastric banding operations: a prospective randomized trial.
Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Intravenous; Clinical Protocols; Female; Fentanyl; Gastroplasty; Humans; Hyperalgesia; Laparoscopy; Male; Middle Aged; Obesity, Morbid; Pain Measurement; Pain, Postoperative; Piperidines; Remifentanil; Respiration; Young Adult | 2012 |
Ketamine and magnesium association reduces morphine consumption after scoliosis surgery: prospective randomised double-blind study.
Topics: Adolescent; Analgesia, Patient-Controlled; Analgesics; Child; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hyperalgesia; Infusions, Intravenous; Internal Fixators; Intraoperative Complications; Ketamine; Magnesium Sulfate; Male; Morphine; Pain, Postoperative; Patient Satisfaction; Piperidines; Postoperative Nausea and Vomiting; Prospective Studies; Prosthesis Implantation; Remifentanil; Scoliosis; Sleep; Spinal Fusion | 2014 |
Failure of intrathecal ketorolac to reduce remifentanil-induced postinfusion hyperalgesia in humans.
Topics: Adult; Analgesics, Opioid; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Hot Temperature; Humans; Hyperalgesia; Infusions, Intravenous; Injections, Spinal; Ketorolac; Male; Piperidines; Remifentanil; Stimulation, Chemical; Treatment Failure; Young Adult | 2015 |
Evaluation of the effect of ketamine on remifentanil-induced hyperalgesia: a double-blind, randomized study.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Double-Blind Method; Female; Humans; Hyperalgesia; Ketamine; Male; Middle Aged; Morphine; Pain, Postoperative; Piperidines; Prospective Studies; Remifentanil; Treatment Outcome | 2015 |
Effects of Different Anesthetics on Pain Processing in an Experimental Human Pain Model.
Topics: Adult; Analgesics, Opioid; Anesthetics; Female; Humans; Hyperalgesia; Ketamine; Male; Pain; Pain Measurement; Pain Threshold; Piperidines; Propofol; Remifentanil; Young Adult | 2016 |
Gradual withdrawal of remifentanil infusion may prevent opioid-induced hyperalgesia.
Topics: Adolescent; Adult; Analgesics, Opioid; Cold Temperature; Cross-Over Studies; Double-Blind Method; Hot Temperature; Humans; Hyperalgesia; Infusions, Intravenous; Male; Pain Measurement; Pain, Postoperative; Piperidines; Pressure; Remifentanil; Young Adult | 2016 |
A randomized phase I trial evaluating the effects of inhaled 50-50% N2 O-O2 on remifentanil-induced hyperalgesia and allodynia in human volunteers.
Topics: Adult; Analgesics, Opioid; Cross-Over Studies; Double-Blind Method; Healthy Volunteers; Humans; Hyperalgesia; Infusions, Intravenous; Male; Nitrous Oxide; Pain Measurement; Piperidines; Remifentanil; Young Adult | 2016 |
Preoperative But Not Postoperative Flurbiprofen Axetil Alleviates Remifentanil-induced Hyperalgesia After Laparoscopic Gynecological Surgery: A Prospective, Randomized, Double-blinded, Trial.
Topics: Adult; Analgesics, Opioid; Anesthetics, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; Female; Flurbiprofen; Forearm; Gynecologic Surgical Procedures; Humans; Hyperalgesia; Laparoscopy; Methyl Ethers; Middle Aged; Pain Threshold; Pain, Postoperative; Piperidines; Postoperative Care; Preoperative Care; Remifentanil; Sevoflurane; Sufentanil; Touch; Treatment Outcome | 2017 |
Low-dose butorphanol alleviates remifetanil-induced hyperalgesia in patients undergoing laparoscopic cholecystectomy.
Topics: Adult; Analgesics, Opioid; Anesthesia, General; Butorphanol; Cholecystectomy, Laparoscopic; Double-Blind Method; Female; Fentanyl; Humans; Hyperalgesia; Male; Middle Aged; Narcotic Antagonists; Pain Measurement; Pain, Postoperative; Piperidines; Receptors, Opioid, kappa; Receptors, Opioid, mu; Remifentanil | 2016 |
Influence of high-dose intraoperative remifentanil with intravenous ibuprofen on postoperative morphine consumption in patients undergoing pancreaticoduodenectomy: a randomized trial.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Cyclooxygenase Inhibitors; Female; Humans; Hyperalgesia; Ibuprofen; Infusions, Intravenous; Intraoperative Care; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Pancreaticoduodenectomy; Piperidines; Postoperative Period; Receptors, N-Methyl-D-Aspartate; Remifentanil | 2016 |
Preoperative butorphanol and flurbiprofen axetil therapy attenuates remifentanil-induced hyperalgesia after laparoscopic gynaecological surgery: a randomized double-blind controlled trial.
Topics: Adult; Butorphanol; Double-Blind Method; Drug Therapy, Combination; Female; Flurbiprofen; Gynecologic Surgical Procedures; Humans; Hyperalgesia; Laparoscopy; Middle Aged; Piperidines; Remifentanil | 2016 |
Preoperative and intraoperative continuous use of dexmedetomidine on hyperalgesia after patients' remifentanil anesthesia.
Topics: Adult; Aged; Anesthesia, General; Atracurium; Dexmedetomidine; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hyperalgesia; Hypnotics and Sedatives; Intraoperative Care; Male; Middle Aged; Neuromuscular Blocking Agents; Piperidines; Preoperative Care; Remifentanil; Treatment Outcome | 2017 |
Pre-treatment with morphine does not prevent the development of remifentanil-induced hyperalgesia.
Topics: Adolescent; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, General; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hyperalgesia; Intraoperative Care; Male; Morphine; Orthopedic Procedures; Pain Measurement; Pain, Postoperative; Piperidines; Premedication; Prospective Studies; Remifentanil; Scoliosis | 2008 |
[The effects of lornoxicam in preventing remifentanil-induced postoperative hyperalgesia].
Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Intravenous; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Hyperalgesia; Hysterectomy; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Piperidines; Preoperative Care; Propofol; Remifentanil; Sensory Thresholds | 2009 |
The endogenous opioid system is not involved in modulation of opioid-induced hyperalgesia.
Topics: Adult; Analgesics, Opioid; Blood Pressure; Cross-Over Studies; Double-Blind Method; Heart Rate; Humans; Hyperalgesia; Male; Middle Aged; Naloxone; Narcotic Antagonists; Pain Measurement; Piperidines; Remifentanil; Young Adult | 2011 |
Maintenance anaesthetics during remifentanil-based anaesthesia might affect postoperative pain control after breast cancer surgery.
Topics: Adult; Aged; Analgesics, Opioid; Anesthetics, Inhalation; Anesthetics, Intravenous; Breast Neoplasms; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Female; Humans; Hyperalgesia; Methyl Ethers; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Piperidines; Propofol; Prospective Studies; Remifentanil; Sevoflurane | 2010 |
Effects of COX inhibition on experimental pain and hyperalgesia during and after remifentanil infusion in humans.
Topics: Adult; Analgesics, Opioid; Blood Pressure; Cross-Over Studies; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Interactions; Humans; Hyperalgesia; Isoxazoles; Ketorolac; Male; Middle Aged; Pain; Pain Measurement; Pain Threshold; Physical Stimulation; Piperidines; Remifentanil; Time Factors; Young Adult | 2011 |
The ED50 and ED95 of ketamine for prevention of postoperative hyperalgesia after remifentanil-based anaesthesia in patients undergoing laparoscopic cholecystectomy.
Topics: Analgesics; Anesthetics, Intravenous; Cholecystectomy, Laparoscopic; Dose-Response Relationship, Drug; Female; Humans; Hyperalgesia; Ketamine; Male; Middle Aged; Pain Measurement; Pain, Postoperative; Piperidines; Remifentanil | 2011 |
[Clonidine for remifentanil-induced hyperalgesia: a double-blind randomized, placebo-controlled study of clonidine under intra-operative use of remifentanil in elective surgery of the shoulder].
Topics: Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthetics, Intravenous; Arthroscopy; Austria; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hyperalgesia; Male; Middle Aged; Morphine; Pain Measurement; Pain, Postoperative; Piperidines; Preanesthetic Medication; Remifentanil; Shoulder; Shoulder Injuries; Shoulder Pain | 2011 |
Magnesium sulfate prevents remifentanil-induced postoperative hyperalgesia in patients undergoing thyroidectomy.
Topics: Adult; Aged; Analgesics; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Intravenous; Blood Pressure; Double-Blind Method; Female; Heart Rate; Humans; Hyperalgesia; Magnesium Sulfate; Male; Middle Aged; Pain Measurement; Pain Threshold; Pain, Postoperative; Physical Stimulation; Piperidines; Recovery Room; Remifentanil; Thyroidectomy; Young Adult | 2011 |
Target-controlled dosing of remifentanil during cardiac surgery reduces postoperative hyperalgesia.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Blood Pressure; Cardiac Surgical Procedures; Double-Blind Method; Drug Delivery Systems; Electroencephalography; Female; Heart Rate; Humans; Hyperalgesia; Male; Middle Aged; Morphine; Pain Measurement; Pain Threshold; Pain, Postoperative; Physical Stimulation; Piperidines; Postoperative Nausea and Vomiting; Preanesthetic Medication; Remifentanil; Sternotomy | 2011 |
Modulation of remifentanil-induced postinfusion hyperalgesia by the β-blocker propranolol in humans.
Topics: Adolescent; Adult; Analgesics; Cross-Over Studies; Double-Blind Method; Humans; Hyperalgesia; Male; Pain Measurement; Physical Stimulation; Piperidines; Propranolol; Remifentanil; Treatment Outcome | 2012 |
[The role of magnesium in preventing postoperative hyperalgesia].
Topics: Administration, Intravenous; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Female; Humans; Hyperalgesia; Hysterectomy; Intraoperative Period; Magnesium; Middle Aged; Morphine; Pain, Postoperative; Piperidines; Preanesthetic Medication; Remifentanil; Tramadol | 2012 |
Opioid-independent mechanisms supporting offset analgesia and temporal sharpening of nociceptive information.
Topics: Adult; Analgesics, Opioid; Female; Humans; Hyperalgesia; Male; Naloxone; Narcotic Antagonists; Nociceptors; Opioid Peptides; Piperidines; Receptors, Opioid, mu; Remifentanil; Young Adult | 2012 |
A comparison of ketamine and paracetamol for preventing remifentanil induced hyperalgesia in patients undergoing total abdominal hysterectomy.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Female; Humans; Hyperalgesia; Hysterectomy; Ketamine; Middle Aged; Piperidines; Remifentanil | 2012 |
Mechanisms of postoperative pain: clinical indications for a contribution of central neuronal sensitization.
Topics: Adult; Aged; Analgesics, Opioid; Anesthesia, General; Double-Blind Method; Female; Hot Temperature; Humans; Hyperalgesia; Hysterectomy; Middle Aged; Pain Measurement; Pain, Postoperative; Piperidines; Remifentanil | 2002 |
Modulation of remifentanil-induced analgesia, hyperalgesia, and tolerance by small-dose ketamine in humans.
Topics: Adult; Analgesics, Opioid; Blood Gas Analysis; Cross-Over Studies; Double-Blind Method; Drug Interactions; Drug Tolerance; Electric Stimulation; Excitatory Amino Acid Antagonists; Female; Humans; Hyperalgesia; Ketamine; Male; Pain Measurement; Pain Threshold; Piperidines; Remifentanil | 2003 |
The mu-opioid agonist remifentanil attenuates hyperalgesia evoked by blunt and punctuated stimuli with different potency: a pharmacological evaluation of the freeze lesion in humans.
Topics: Adolescent; Adult; Analgesics, Opioid; Dose-Response Relationship, Drug; Double-Blind Method; Electric Stimulation; Female; Freezing; Humans; Hyperalgesia; Male; Pain; Pain Measurement; Physical Stimulation; Piperidines; Receptors, Opioid, mu; Remifentanil; Sensory Thresholds; Skin Temperature; Time Factors; Wounds and Injuries | 2003 |
Differential modulation of remifentanil-induced analgesia and postinfusion hyperalgesia by S-ketamine and clonidine in humans.
Topics: Adrenergic alpha-Agonists; Adult; Analgesics, Opioid; Anesthetics, Dissociative; Blood Pressure; Clonidine; Cross-Over Studies; Double-Blind Method; Electric Stimulation; Half-Life; Humans; Hyperalgesia; Infusions, Intravenous; Ketamine; Male; Oxygen; Pain Measurement; Physical Stimulation; Piperidines; Receptors, Opioid, mu; Remifentanil; Substance Withdrawal Syndrome | 2003 |
Intravenous remifentanil produces withdrawal hyperalgesia in volunteers with capsaicin-induced hyperalgesia.
Topics: Adult; Analgesics, Opioid; Capsaicin; Female; Humans; Hyperalgesia; Male; Nausea; Oxyhemoglobins; Pain Measurement; Piperidines; Remifentanil | 2003 |
Short-term infusion of the mu-opioid agonist remifentanil in humans causes hyperalgesia during withdrawal.
Topics: Adult; Analgesics, Opioid; Cross-Over Studies; Excitatory Amino Acid Antagonists; Hot Temperature; Humans; Hyperalgesia; Ketamine; Pain; Physical Stimulation; Piperidines; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Remifentanil; Substance Withdrawal Syndrome | 2003 |
Naloxone provokes similar pain facilitation as observed after short-term infusion of remifentanil in humans.
Topics: Adult; Analgesics, Opioid; Cross-Over Studies; Dermis; Electric Stimulation; Humans; Hyperalgesia; Male; Naloxone; Narcotic Antagonists; Pain; Piperidines; Receptors, Opioid, mu; Remifentanil; Sodium Chloride | 2003 |
A randomized study of the effect of oral lamotrigine and hydromorphone on pain and hyperalgesia following heat/capsaicin sensitization.
Topics: Adult; Analgesics, Opioid; Anticonvulsants; Capsaicin; Double-Blind Method; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Hot Temperature; Humans; Hydromorphone; Hyperalgesia; Lamotrigine; Pain; Pain Measurement; Piperidines; Remifentanil; Triazines | 2003 |
The effects of remifentanil and gabapentin on hyperalgesia in a new extended inflammatory skin pain model in healthy volunteers.
Topics: Acetates; Adult; Amines; Analgesics, Opioid; Cross-Over Studies; Cyclohexanecarboxylic Acids; Diazepam; Double-Blind Method; Drug Synergism; Excitatory Amino Acid Antagonists; Female; GABA Modulators; Gabapentin; gamma-Aminobutyric Acid; Humans; Hyperalgesia; Inflammation; Male; Pain Measurement; Pain Threshold; Physical Stimulation; Piperidines; Reaction Time; Remifentanil; Skin; Sunburn; Treatment Outcome | 2004 |
Remifentanil-induced postoperative hyperalgesia and its prevention with small-dose ketamine.
Topics: Adult; Aged; Female; Humans; Hyperalgesia; Ketamine; Male; Middle Aged; Pain, Postoperative; Piperidines; Remifentanil | 2005 |
Opioid tolerance and hyperalgesia in chronic pain patients after one month of oral morphine therapy: a preliminary prospective study.
Topics: Administration, Oral; Adolescent; Adult; Aged; Analgesics, Opioid; Chronic Disease; Drug Administration Schedule; Drug Tolerance; Follow-Up Studies; Humans; Hyperalgesia; Infusions, Intravenous; Low Back Pain; Middle Aged; Morphine; Pain Threshold; Piperidines; Prospective Studies; Remifentanil | 2006 |
Modulation of remifentanil-induced analgesia and postinfusion hyperalgesia by parecoxib in humans.
Topics: Adult; Analgesia; Analgesics, Opioid; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Interactions; Humans; Hyperalgesia; Infusions, Intravenous; Isoxazoles; Ketamine; Male; Middle Aged; Pain Threshold; Piperidines; Remifentanil | 2006 |
Modulation of remifentanil-induced postinfusion hyperalgesia by propofol.
Topics: Adult; Anesthetics; Cross-Over Studies; Double-Blind Method; Humans; Hyperalgesia; Infusions, Intravenous; Male; Pain Measurement; Piperidines; Propofol; Remifentanil | 2007 |
Administration of fentanyl before remifentanil-based anaesthesia has no influence on post-operative pain or analgesic consumption.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Anesthesia, Intravenous; Anesthetics, Intravenous; Anterior Cruciate Ligament; Anterior Cruciate Ligament Injuries; Double-Blind Method; Female; Fentanyl; Humans; Hyperalgesia; Male; Middle Aged; Oxycodone; Pain, Postoperative; Piperidines; Preanesthetic Medication; Remifentanil; Reoperation; Treatment Failure | 2008 |
Effect of remifentanil on pain and secondary hyperalgesia associated with the heat--capsaicin sensitization model in healthy volunteers.
Topics: Adult; Analgesics, Opioid; Capsaicin; Female; Hot Temperature; Humans; Hyperalgesia; Male; Middle Aged; Pain Measurement; Piperidines; Remifentanil | 2001 |
99 other study(ies) available for remifentanil and Allodynia
| Article | Year |
|---|---|
Effects of remifentanil on human C20 microglial pro-inflammatory activation.
Topics: Adult; Analgesics, Opioid; Brain-Derived Neurotrophic Factor; Cell Line; Humans; Hyperalgesia; Interleukin-6; Microglia; Remifentanil | 2021 |
P2Y1 purinergic receptor inhibition attenuated remifentanil-induced postoperative hyperalgesia via decreasing NMDA receptor phosphorylation in dorsal root ganglion.
Topics: Animals; Ganglia, Spinal; Hyperalgesia; Pain, Postoperative; Phosphorylation; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P2Y1; Remifentanil; Spinal Cord | 2021 |
Artesunate Reduces Remifentanil-induced Hyperalgesia and Peroxiredoxin-3 Hyperacetylation via Modulating Spinal Metabotropic Glutamate Receptor 5 in Rats.
Topics: Animals; Artesunate; Hyperalgesia; Peroxiredoxin III; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Remifentanil; Spinal Cord | 2022 |
Changes of Entropy Index and Cerebral Oxygen Metabolism in the Maintenance of Remifentanil Anesthesia and Their Predictive Value for Postoperative Hyperalgesia.
Topics: Adolescent; Adult; Analgesics, Opioid; Anesthesia, General; Brain; Computational Biology; Female; Humans; Hyperalgesia; Male; Middle Aged; Oxygen Consumption; Pain, Postoperative; Remifentanil; Young Adult | 2022 |
Spinal NLRP3 inflammasome activation mediates IL-1β release and contributes to remifentanil-induced postoperative hyperalgesia by regulating NMDA receptor NR1 subunit phosphorylation and GLT-1 expression in rats.
Topics: Animals; Caspases; Hyperalgesia; Inflammasomes; Interleukin 1 Receptor Antagonist Protein; Naloxone; NLR Family, Pyrin Domain-Containing 3 Protein; NLR Proteins; Phosphorylation; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Remifentanil; Toll-Like Receptor 4 | 2022 |
Comment on: Effects of opioid-free anesthesia on postoperative morphine consumption after bariatric surgery.
Topics: Analgesics, Opioid; Anesthesia; Bariatric Surgery; Humans; Hyperalgesia; Morphine; Pain, Postoperative; Remifentanil | 2022 |
Nano-Carbon-Based Application of Parecoxib Sodium Combined with Hydromorphone in Preventing Anesthesia Hyperalgesia Caused by Remifentanil after Thyroidectomy.
Topics: Analgesics, Opioid; Anesthesia; Humans; Hydromorphone; Hyperalgesia; Isoxazoles; Pain; Piperidines; Remifentanil; Thyroidectomy | 2022 |
Opioid-induced hyperalgesia: Are thalamic T-type calcium channels treatment targets?
Topics: Analgesics, Opioid; Animals; Calcium Channels, T-Type; Humans; Hyperalgesia; Pain; Pain, Postoperative; Remifentanil | 2022 |
Thalamocortical circuits drive remifentanil-induced postoperative hyperalgesia.
Topics: Analgesics; Animals; Calcium Channels, T-Type; Hyperalgesia; Mice; Pain, Postoperative; Remifentanil | 2022 |
Blocking SphK/S1P/S1PR1 axis signaling pathway alleviates remifentanil-induced hyperalgesia in rats.
Topics: Animals; Caspases; Ceramides; Cytokines; Hyperalgesia; Interleukin-18; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Remifentanil; Signal Transduction; Sphingosine-1-Phosphate Receptors | 2023 |
Association between intraoperative remifentanil use and postoperative hyperalgesia in adolescent idiopathic scoliosis surgery: a retrospective study.
Topics: Adolescent; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, General; Humans; Hyperalgesia; Morphine Derivatives; Pain; Postoperative Complications; Remifentanil; Retrospective Studies; Scoliosis | 2023 |
Opioid infusions at different times of the day produce varying degrees of opioid-induced hyperalgesia.
Topics: Analgesics, Opioid; Animals; Carboxylesterase; Humans; Hyperalgesia; Male; Pain, Postoperative; Piperidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Remifentanil; Sufentanil | 2023 |
Chemokine CCL7 regulates spinal phosphorylation of GluA1-containing AMPA receptor via interleukin-18 in remifentanil-induced hyperalgesia in rats.
Topics: Analgesics, Opioid; Animals; Chemokine CCL7; Hyperalgesia; Interleukin-18; Male; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Remifentanil; Spinal Cord | 2019 |
Ketamine reduces remifentanil-induced postoperative hyperalgesia mediated by CaMKII-NMDAR in the primary somatosensory cerebral cortex region in mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Analgesics; Analgesics, Opioid; Animals; Benzylamines; Blotting, Western; Calcium Channel Agonists; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Fluorescent Antibody Technique; Hyperalgesia; Ketamine; Mice; Pain Threshold; Pain, Postoperative; Postoperative Complications; Protein Kinase Inhibitors; Receptors, N-Methyl-D-Aspartate; Remifentanil; Somatosensory Cortex; Sulfonamides | 2020 |
TRPV1 and spinal astrocyte activation contribute to remifentanil-induced hyperalgesia in rats.
Topics: Animals; Astrocytes; Ganglia, Spinal; Hyperalgesia; Male; Pain Threshold; Piperidines; Rats, Sprague-Dawley; Remifentanil; Spinal Cord; TRPV Cation Channels | 2019 |
Acid-sensing ion channel 3 expression is increased in dorsal root ganglion, hippocampus and hypothalamus in remifentanil-induced hyperalgesia in rats.
Topics: Acid Sensing Ion Channels; Analgesics, Opioid; Animals; Ganglia, Spinal; Gene Expression; Hippocampus; Hyperalgesia; Hypothalamus; Male; Rats; Rats, Sprague-Dawley; Remifentanil | 2020 |
Dezocine attenuates the remifentanil-induced postoperative hyperalgesia by inhibition of phosphorylation of CaMKⅡα.
Topics: Analgesics, Opioid; Animals; Bridged Bicyclo Compounds, Heterocyclic; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Hippocampus; Hyperalgesia; Male; Mice, Inbred ICR; Pain, Postoperative; Phosphorylation; Postoperative Period; Remifentanil; Spinal Cord; Tetrahydronaphthalenes | 2020 |
Spinal caspase-6 contributes to remifentanil-induced hyperalgesia via regulating CCL21/CXCR3 pathway in rats.
Topics: Analgesics, Opioid; Animals; Caspase 6; Chemokine CCL21; Hot Temperature; Hyperalgesia; Male; Physical Stimulation; Rats; Rats, Sprague-Dawley; Receptors, CXCR3; Remifentanil; Signal Transduction; Spinal Cord | 2020 |
Spinal hevin mediates membrane trafficking of GluA1-containing AMPA receptors in remifentanil-induced postoperative hyperalgesia in mice.
Topics: Analgesics, Opioid; Animals; Calcium-Binding Proteins; Extracellular Matrix Proteins; Hyperalgesia; Male; Mice; Pain, Postoperative; Protein Transport; Receptors, AMPA; Remifentanil; Spinal Cord | 2020 |
NMDA Receptor Modulates Spinal Iron Accumulation Via Activating DMT1(-)IRE in Remifentanil-Induced Hyperalgesia.
Topics: Analgesics, Opioid; Animals; Cation Transport Proteins; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hyperalgesia; Iron; Iron Chelating Agents; Male; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Remifentanil; Signal Transduction; Spine | 2021 |
Spinal and Peripheral Mechanisms Individually Lead to the Development of Remifentanil-induced Hyperalgesia.
Topics: Analgesics, Opioid; Animals; Ganglia, Spinal; Hyperalgesia; Piperidines; Rats; Rats, Sprague-Dawley; Remifentanil; Spinal Cord | 2020 |
Perioperative Precedex: Whole New Ball Game or Whole New Ball of Wax?
Topics: Dexmedetomidine; Double-Blind Method; Humans; Hyperalgesia; Remifentanil; Thyroidectomy | 2021 |
P2X4 receptor in the dorsal horn contributes to BDNF/TrkB and AMPA receptor activation in the pathogenesis of remifentanil-induced postoperative hyperalgesia in rats.
Topics: Animals; Brain-Derived Neurotrophic Factor; Female; Hyperalgesia; Male; Rats; Rats, Sprague-Dawley; Receptor, trkB; Receptors, AMPA; Receptors, Purinergic P2X4; Remifentanil; Spinal Cord Dorsal Horn | 2021 |
A Role for Transmembrane Protein 16C/Slack Impairment in Excitatory Nociceptive Synaptic Plasticity in the Pathogenesis of Remifentanil-induced Hyperalgesia in Rats.
Topics: Animals; Hyperalgesia; Neuronal Plasticity; Nociception; Rats; Rats, Sprague-Dawley; Remifentanil | 2021 |
P2Y1 Purinergic Receptor Contributes to Remifentanil-Induced Cold Hyperalgesia via Transient Receptor Potential Melastatin 8-Dependent Regulation of N-methyl-d-aspartate Receptor Phosphorylation in Dorsal Root Ganglion.
Topics: Analgesics; Animals; Behavior, Animal; Cold Temperature; Disease Models, Animal; Ganglia, Spinal; Hyperalgesia; Male; Pain Threshold; Phosphorylation; Protein Transport; Purinergic P2Y Receptor Antagonists; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P2Y1; Remifentanil; Signal Transduction; TRPM Cation Channels | 2021 |
CXCL13 regulates the trafficking of GluN2B-containing NMDA receptor via IL-17 in the development of remifentanil-induced hyperalgesia in rats.
Topics: Animals; Chemokine CXCL13; Hyperalgesia; Interleukin-17; Male; Nociception; Pain Threshold; Piperidines; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Remifentanil; RNA, Messenger; Spinal Cord Dorsal Horn | 2017 |
Role of mitochondrial Ca
Topics: Analgesics, Opioid; Animals; Calcium; Hyperalgesia; Male; Mitochondria; Phosphorylation; Piperidines; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Remifentanil; Spinal Cord | 2018 |
Toll-like receptor 4 deficient mice do not develop remifentanil-induced mechanical hyperalgesia: An experimental randomised animal study.
Topics: Analgesics, Opioid; Animals; Female; Hyperalgesia; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Physical Stimulation; Random Allocation; Remifentanil; Toll-Like Receptor 4 | 2018 |
Spinal Protein Kinase Mζ Regulates α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Receptor Trafficking and Dendritic Spine Plasticity via Kalirin-7 in the Pathogenesis of Remifentanil-induced Postincisional Hyperalgesia in Rats.
Topics: Analgesics, Opioid; Animals; Dendritic Spines; Guanine Nucleotide Exchange Factors; Hyperalgesia; Male; Neuronal Plasticity; Organ Culture Techniques; Pain, Postoperative; Protein Kinase C; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Remifentanil; Surgical Wound | 2018 |
The Mechanism of Hyperalgesia and Anxiety Induced by Remifentanil: Phosphorylation of GluR1 Receptors in the Anterior Cingulate Cortex.
Topics: Analgesics, Opioid; Animals; Anxiety; Excitatory Amino Acid Agonists; Gyrus Cinguli; Hyperalgesia; Ibotenic Acid; Male; Phosphorylation; Piperidines; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Remifentanil | 2018 |
Attenuation of Remifentanil-Induced Hyperalgesia by Betulinic Acid Associates with Inhibiting Oxidative Stress and Inflammation in Spinal Dorsal Horn.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Betulinic Acid; Drug Interactions; Ganglia, Spinal; Hyperalgesia; Inflammation; Interleukin-1beta; Male; Oxidative Stress; Pain, Postoperative; Pentacyclic Triterpenes; Random Allocation; Rats; Rats, Sprague-Dawley; Remifentanil; Spinal Cord Dorsal Horn; Superoxide Dismutase; Triterpenes; Tumor Necrosis Factor-alpha; Tyrosine | 2018 |
Electroacupuncture Treatment Alleviates the Remifentanil-Induced Hyperalgesia by Regulating the Activities of the Ventral Posterior Lateral Nucleus of the Thalamus Neurons in Rats.
Topics: Analgesics, Opioid; Animals; Electroacupuncture; Hyperalgesia; Lateral Thalamic Nuclei; Male; Pain; Pain Management; Rats; Rats, Sprague-Dawley; Remifentanil; Treatment Outcome; Ventral Thalamic Nuclei | 2018 |
COX-2 contributed to the remifentanil-induced hyperalgesia related to ephrinB/EphB signaling.
Topics: Animals; Cyclooxygenase 2; Disease Models, Animal; Ephrins; Hyperalgesia; Injections, Spinal; Mice; Pyrazoles; Receptors, N-Methyl-D-Aspartate; Remifentanil; Spinal Cord | 2019 |
Fentanyl versus remifentanil-based TIVA for pediatric scoliosis repair: does it matter?
Topics: Adolescent; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Child; Drug Tolerance; Female; Fentanyl; Humans; Hyperalgesia; Male; Pain, Postoperative; Remifentanil; Retrospective Studies; Scoliosis | 2019 |
[Role of spinal P2X4 receptor in remifentanil-induced postoperative hyperalgesia].
Topics: Animals; Hyperalgesia; Male; Pain, Postoperative; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P2X4; Remifentanil; Spinal Cord | 2019 |
Effects of naloxone on opioid-induced hyperalgesia and tolerance to remifentanil under sevoflurane anesthesia in rats.
Topics: Analgesics, Opioid; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Behavior, Animal; Drug Tolerance; Hyperalgesia; Male; Methyl Ethers; Naloxone; Narcotic Antagonists; Pain Threshold; Physical Stimulation; Piperidines; Pulmonary Alveoli; Rats; Rats, Wistar; Remifentanil; Sevoflurane | 2013 |
No evidence for the development of acute analgesic tolerance during and hyperalgesia after prolonged remifentanil administration in mice.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Drug Tolerance; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Pain Threshold; Piperidines; Remifentanil | 2013 |
Phosphorylated CaMKII levels increase in rat central nervous system after large-dose intravenous remifentanil.
Topics: Analgesics, Opioid; Animals; Brain Mapping; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Central Nervous System; Cerebral Cortex; Hippocampus; Hyperalgesia; Infusions, Intravenous; Male; Morphine; Phosphorylation; Piperidines; Rats; Rats, Sprague-Dawley; Remifentanil; Spinal Cord; Time Factors | 2013 |
Inhibition of glycogen synthase kinase-3β prevents remifentanil-induced hyperalgesia via regulating the expression and function of spinal N-methyl-D-aspartate receptors in vivo and vitro.
Topics: Animals; Blotting, Western; Glycogen Synthase Kinase 3; Hyperalgesia; Male; Patch-Clamp Techniques; Piperidines; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Remifentanil; Spine | 2013 |
Intrathecal injection of JWH015 attenuates remifentanil-induced postoperative hyperalgesia by inhibiting activation of spinal glia in a rat model.
Topics: Anesthetics, Local; Animals; Astrocytes; Behavior, Animal; Blotting, Western; Cannabinoid Receptor Agonists; Cytokines; Hyperalgesia; Immunohistochemistry; Indoles; Injections, Spinal; Macrophage Activation; Male; Neuroglia; Pain, Postoperative; Phosphorylation; Piperidines; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB2; Receptors, N-Methyl-D-Aspartate; Remifentanil; Spinal Cord | 2014 |
Spinal ephrinB/EphB signalling contributed to remifentanil-induced hyperalgesia via NMDA receptor.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Dizocilpine Maleate; Ephrin-B1; Excitatory Amino Acid Antagonists; Hyperalgesia; Male; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, EphB1; Receptors, N-Methyl-D-Aspartate; Remifentanil; Signal Transduction | 2014 |
Intrathecal administration of roscovitine prevents remifentanil-induced postoperative hyperalgesia and decreases the phosphorylation of N-methyl-D-aspartate receptor and metabotropic glutamate receptor 5 in spinal cord.
Topics: Analgesics, Opioid; Animals; Cyclin-Dependent Kinase 5; Hyperalgesia; Injections, Spinal; Male; Motor Activity; Pain Threshold; Pain, Postoperative; Phosphorylation; Piperidines; Protein Kinase Inhibitors; Purines; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, N-Methyl-D-Aspartate; Remifentanil; Roscovitine; Spinal Cord | 2014 |
Amitriptyline, minocycline and maropitant reduce the sevoflurane minimum alveolar concentration and potentiate remifentanil but do not prevent acute opioid tolerance and hyperalgesia in the rat: a randomised laboratory study.
Topics: Amitriptyline; Analgesics, Opioid; Anesthetics, Inhalation; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Hyperalgesia; Male; Methyl Ethers; Minocycline; Nociception; Pain Threshold; Piperidines; Pulmonary Alveoli; Quinuclidines; Random Allocation; Rats, Wistar; Remifentanil; Sevoflurane | 2015 |
Hydrogen-rich saline controls remifentanil-induced hypernociception and NMDA receptor NR1 subunit membrane trafficking through GSK-3β in the DRG in rats.
Topics: Analgesics, Opioid; Animals; Cell Membrane; Ganglia, Spinal; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hydrogen; Hydrogen-Ion Concentration; Hyperalgesia; Male; Nociception; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Remifentanil; Sodium Chloride | 2014 |
Glycogen synthase kinase-3β inhibition prevents remifentanil-induced postoperative hyperalgesia via regulating the expression and function of AMPA receptors.
Topics: Animals; Enzyme Inhibitors; Gene Expression Regulation; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hyperalgesia; Male; Organ Culture Techniques; Pain, Postoperative; Piperidines; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Remifentanil | 2014 |
Hydrogen-rich saline prevents remifentanil-induced hyperalgesia and inhibits MnSOD nitration via regulation of NR2B-containing NMDA receptor in rats.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Excitatory Amino Acid Antagonists; Hot Temperature; Hydrogen; Hyperalgesia; Injections, Intraperitoneal; Male; Nociception; Pain, Postoperative; Phenols; Piperidines; Random Allocation; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Remifentanil; Sodium Chloride; Spinal Cord Dorsal Horn; Superoxide Dismutase; Touch | 2014 |
[Changes of Mu-opioid receptor and neuron-restrictive silencer factor in periaquductal gray in mouse models of remifentanil-induced postoperative hyperalgesia].
Topics: Animals; Disease Models, Animal; Hyperalgesia; Mice; Pain, Postoperative; Periaqueductal Gray; Piperidines; Receptors, Opioid, mu; Remifentanil; Repressor Proteins | 2014 |
Modulating actions of NMDA receptors on pronociceptive effects of locally injected remifentanil in diabetic rats.
Topics: Analgesics, Opioid; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hyperalgesia; Malondialdehyde; N-Methylaspartate; Nitric Oxide; Piperidines; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Remifentanil; Streptozocin | 2014 |
Hyperalgesia and increased sevoflurane minimum alveolar concentration induced by opioids in the rat: a randomised experimental study.
Topics: Analgesics, Opioid; Anesthetics, Inhalation; Animals; Behavior, Animal; Buprenorphine; Hyperalgesia; Ketamine; Male; Methadone; Methyl Ethers; Morphine; Nociception; Pain Threshold; Piperidines; Pulmonary Alveoli; Random Allocation; Rats, Wistar; Remifentanil; Sevoflurane | 2015 |
Inhibition of DOR prevents remifentanil induced postoperative hyperalgesia through regulating the trafficking and function of spinal NMDA receptors in vivo and in vitro.
Topics: Anesthetics, Intravenous; Animals; Disease Models, Animal; Hot Temperature; Hyperalgesia; Lumbar Vertebrae; Male; Naltrexone; Narcotic Antagonists; Oligopeptides; Pain Threshold; Pain, Postoperative; Piperidines; Posterior Horn Cells; Random Allocation; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Remifentanil; Spinal Cord; Tissue Culture Techniques; Touch | 2015 |
Spinal peroxynitrite contributes to remifentanil-induced postoperative hyperalgesia via enhancement of divalent metal transporter 1 without iron-responsive element-mediated iron accumulation in rats.
Topics: Animals; Cation Transport Proteins; Hyperalgesia; Iron; Iron-Regulatory Proteins; Male; Pain, Postoperative; Peroxynitrous Acid; Piperidines; Rats; Rats, Sprague-Dawley; Remifentanil; Spinal Cord | 2015 |
CaMKII Phosphorylation in Primary Somatosensory Cortical Neurons is Involved in the Inhibition of Remifentanil-induced Hyperalgesia by Lidocaine in Male Sprague-Dawley Rats.
Topics: Analgesics, Opioid; Anesthetics, Local; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disease Models, Animal; Hyperalgesia; Lidocaine; Male; Neurons; Phosphorylation; Piperidines; Rats; Rats, Sprague-Dawley; Remifentanil; Somatosensory Cortex | 2016 |
Neuron-restrictive silencer factor in periaqueductal gray contributes to remifentanil-induced postoperative hyperalgesia via repression of the mu-opioid receptor.
Topics: Animals; Disease Models, Animal; Hyperalgesia; Injections, Intraventricular; Mice; Mice, Inbred C57BL; Oligonucleotides, Antisense; Periaqueductal Gray; Piperidines; Receptors, Opioid, mu; Remifentanil; Repressor Proteins; Treatment Outcome | 2015 |
Phosphorylation of the GluN1 subunit in dorsal horn neurons by remifentanil: a mechanism for opioid-induced hyperalgesia.
Topics: Analgesics, Opioid; Animals; Female; Hyperalgesia; Ketamine; Naloxone; Nerve Tissue Proteins; Phosphorylation; Piperidines; Posterior Horn Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Remifentanil; Up-Regulation | 2015 |
Intrathecal injection of KN93 attenuates paradoxical remifentanil-induced postoperative hyperalgesia by inhibiting spinal CaMKII phosphorylation in rats.
Topics: Animals; Benzylamines; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Spinal; Male; Pain, Postoperative; Piperidines; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Remifentanil; Spinal Cord; Sulfonamides | 2015 |
Involvement of CCL3/CCR5 Signaling in Dorsal Root Ganglion in Remifentanil-induced Hyperalgesia in Rats.
Topics: Analgesics, Opioid; Animals; CCR5 Receptor Antagonists; Chemokine CCL3; Cyclohexanes; Disease Models, Animal; Ganglia, Spinal; Hot Temperature; Hyperalgesia; Male; Maraviroc; Piperidines; Rats, Sprague-Dawley; Receptors, CCR5; Remifentanil; RNA, Messenger; Touch; Triazoles | 2016 |
Up-regulation of CXCL1 and CXCR2 contributes to remifentanil-induced hypernociception via modulating spinal NMDA receptor expression and phosphorylation in rats.
Topics: Analgesics, Opioid; Animals; Chemokine CXCL1; Hyperalgesia; Male; Nociception; Phenylurea Compounds; Phosphorylation; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-8B; Receptors, N-Methyl-D-Aspartate; Remifentanil; Spinal Cord; Up-Regulation | 2016 |
Differential Postoperative Effects of Volatile Anesthesia and Intraoperative Remifentanil Infusion in 7511 Thyroidectomy Patients: A Propensity Score Matching Analysis.
Topics: Adult; Anesthesia, Inhalation; Anesthetics, Intravenous; Female; Humans; Hyperalgesia; Male; Middle Aged; Pain, Postoperative; Piperidines; Propensity Score; Remifentanil; Retrospective Studies; Thyroidectomy | 2016 |
Remifentanil and worse patient-reported outcomes regarding postoperative pain management after thyroidectomy.
Topics: Adult; Aged; Analgesics, Opioid; Anesthesia, Intravenous; Anesthetics, Intravenous; Drug Administration Schedule; Female; Humans; Hyperalgesia; Male; Middle Aged; Pain Management; Pain, Postoperative; Patient Reported Outcome Measures; Piperidines; Remifentanil; Thyroidectomy | 2016 |
Involvement of Spinal PKMζ Expression and Phosphorylation in Remifentanil-Induced Long-Term Hyperalgesia in Rats.
Topics: Animals; Hyperalgesia; Memory, Long-Term; Neuralgia; Phosphorylation; Piperidines; Posterior Horn Cells; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Remifentanil; Spinal Cord; Up-Regulation | 2017 |
PICK1 Regulates the Expression and Trafficking of AMPA Receptors in Remifentanil-Induced Hyperalgesia.
Topics: Analgesics, Opioid; Animals; Carrier Proteins; Cytoskeletal Proteins; Gene Expression Regulation; Hyperalgesia; Male; Nuclear Proteins; Piperidines; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Remifentanil | 2016 |
A comparison of intrathecal magnesium and ketamine in attenuating remifentanil-induced hyperalgesia in rats.
Topics: Animals; Dose-Response Relationship, Drug; Hyperalgesia; Injections, Spinal; Ketamine; Magnesium Sulfate; Male; Pain Measurement; Pain Threshold; Pain, Postoperative; Piperidines; Rats; Remifentanil | 2016 |
Spinal WNT pathway contributes to remifentanil induced hyperalgesia through regulating fractalkine and CX3CR1 in rats.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Animals; beta Catenin; Chemokine CX3CL1; CX3C Chemokine Receptor 1; Frizzled Receptors; Hyperalgesia; Pain, Postoperative; Piperidines; Rats, Sprague-Dawley; Receptors, Chemokine; Remifentanil; Spinal Cord; Wnt Signaling Pathway; Wnt3A Protein | 2016 |
Spinal mitochondrial-derived ROS contributes to remifentanil-induced postoperative hyperalgesia via modulating NMDA receptor in rats.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Animals; Cyclic N-Oxides; Hyperalgesia; Male; Mitochondria; Pain Threshold; Pain, Postoperative; Phosphorylation; Piperidines; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Remifentanil; Spinal Cord | 2016 |
The role of p38MAPK activation in spinal dorsal horn in remifentanil-induced postoperative hyperalgesia in rats.
Topics: Analgesics, Opioid; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Disease Models, Animal; Enzyme Activation; Hyperalgesia; Imidazoles; Male; p38 Mitogen-Activated Protein Kinases; Pain Measurement; Pain Threshold; Pain, Postoperative; Piperidines; Pyridines; Rats; Rats, Sprague-Dawley; Remifentanil; Spinal Cord Dorsal Horn; Time Factors | 2016 |
Cathepsin S in the spinal microglia contributes to remifentanil-induced hyperalgesia in rats.
Topics: Analgesics; Animals; Cathepsins; Free Radical Scavengers; Hot Temperature; Hyperalgesia; Male; Microglia; Minocycline; Neurons; Phosphorylation; Piperidines; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, N-Methyl-D-Aspartate; Remifentanil; Spinal Cord; Touch; Up-Regulation | 2017 |
Prevention of Remifentanil Induced Postoperative Hyperalgesia by Dexmedetomidine via Regulating the Trafficking and Function of Spinal NMDA Receptors as well as PKC and CaMKII Level In Vivo and In Vitro.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cells, Cultured; Chemoprevention; Dexmedetomidine; Hyperalgesia; Male; Pain Management; Pain, Postoperative; Phosphorylation; Piperidines; Postoperative Period; Protein Kinase C; Protein Transport; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Remifentanil; Signal Transduction; Spinal Cord | 2017 |
N-acetyl-cysteine attenuates remifentanil-induced postoperative hyperalgesia via inhibiting matrix metalloproteinase-9 in dorsal root ganglia.
Topics: Acetylcysteine; Analgesics, Opioid; Animals; Blotting, Western; Enzyme Activation; Free Radical Scavengers; Ganglia, Spinal; Hyperalgesia; Infusions, Subcutaneous; Injections, Intraperitoneal; Male; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinases; Pain Measurement; Phosphorylation; Piperidines; Postoperative Period; Protein Kinase C; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Remifentanil | 2017 |
Magnesium sulphate attenuate remifentanil-induced postoperative hyperalgesia via regulating tyrosine phosphorylation of the NR
Topics: Analgesics; Animals; Hyperalgesia; Hypnotics and Sedatives; Injections, Spinal; Lumbar Vertebrae; Magnesium Sulfate; Phosphorylation; Piperidines; Postoperative Complications; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Remifentanil; Signal Transduction; Spinal Cord; Tyrosine | 2017 |
Enhancement of spinal N-methyl-D-aspartate receptor function by remifentanil action at delta-opioid receptors as a mechanism for acute opioid-induced hyperalgesia or tolerance.
Topics: Analgesics, Opioid; Animals; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Electrophysiology; Female; Hyperalgesia; Naloxone; Narcotic Antagonists; Patch-Clamp Techniques; Piperidines; Posterior Horn Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, delta; Receptors, Opioid, mu; Remifentanil | 2008 |
Propofol alters ketamine effect on opiate-induced hyperalgesia.
Topics: Analgesics; Analgesics, Opioid; Anesthetics, Intravenous; Drug Interactions; Drug Tolerance; Humans; Hyperalgesia; Intraoperative Care; Ketamine; Pain, Postoperative; Piperidines; Propofol; Remifentanil; Research Design | 2009 |
[Effects of general anesthesia using ketamine and remifentanil on postoperative pain management for patients undergoing laparotomy].
Topics: Adult; Aged; Anesthesia, General; Anti-Inflammatory Agents, Non-Steroidal; Elective Surgical Procedures; Female; Humans; Hyperalgesia; Ketamine; Laparotomy; Male; Middle Aged; Pain, Postoperative; Pentazocine; Piperidines; Remifentanil; Retrospective Studies | 2009 |
Induction of synaptic long-term potentiation after opioid withdrawal.
Topics: Analgesics, Opioid; Animals; Calcium; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Evoked Potentials; GTP-Binding Proteins; Hyperalgesia; Long-Term Potentiation; Male; Nerve Fibers, Unmyelinated; Patch-Clamp Techniques; Piperidines; Posterior Horn Cells; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, mu; Remifentanil; Signal Transduction; Substance Withdrawal Syndrome; Synapses | 2009 |
Pronociceptive effects of remifentanil in a mouse model of postsurgical pain: effect of a second surgery.
Topics: Analgesics, Opioid; Anesthetics, Intravenous; Animals; Dose-Response Relationship, Drug; Hot Temperature; Hyperalgesia; Male; Mice; Nociceptors; Pain Threshold; Pain, Postoperative; Physical Stimulation; Piperidines; Remifentanil | 2009 |
Systemic lidocaine inhibits remifentanil-induced hyperalgesia via the inhibition of cPKCgamma membrane translocation in spinal dorsal horn of rats.
Topics: Analgesics, Opioid; Anesthesia; Anesthetics, Local; Animals; Behavior, Animal; Cell Membrane; Dose-Response Relationship, Drug; Fluorescent Antibody Technique; Foot Injuries; Hyperalgesia; Lidocaine; Male; Pain Measurement; Piperidines; Posterior Horn Cells; Protein Kinase C; Protein Transport; Rats; Rats, Sprague-Dawley; Remifentanil; Subcellular Fractions | 2009 |
Tyrosine phosphorylation of the N-Methyl-D-Aspartate receptor 2B subunit in spinal cord contributes to remifentanil-induced postoperative hyperalgesia: the preventive effect of ketamine.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Excitatory Amino Acid Antagonists; Glutamic Acid; Hyperalgesia; Inflammation Mediators; Ketamine; Male; Nociceptors; Pain, Postoperative; Phosphorylation; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Remifentanil; Spinal Cord; Synaptic Transmission; Tyrosine | 2009 |
No hyperalgesia following opioid withdrawal after the oripavine derivative etorphine compared to remifentanil and sufentanil.
Topics: Afferent Pathways; Analgesics, Opioid; Animals; Blood Pressure; Bradycardia; Dogs; Dose-Response Relationship, Drug; Etorphine; Evoked Potentials, Somatosensory; Heart Rate; Hyperalgesia; Hypotension; Naloxone; Narcotic Antagonists; Piperidines; Remifentanil; Substance Withdrawal Syndrome; Sufentanil | 2010 |
Opioid-induced hyperalgesia: pain hurts?
Topics: Analgesics, Opioid; Drug Tolerance; Humans; Hyperalgesia; Pain, Postoperative; Piperidines; Remifentanil | 2010 |
Delayed postoperative latent pain sensitization revealed by the systemic administration of opioid antagonists in mice.
Topics: Animals; Dizocilpine Maleate; Dynorphins; Hyperalgesia; Male; Mice; Naloxone; Naltrexone; Narcotic Antagonists; Pain; Pain Threshold; Piperidines; Postoperative Complications; Reaction Time; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa; Remifentanil; Spinal Cord | 2011 |
[Cohort study of remifentanil-induced hyperalgesia in postoperative patients].
Topics: Adolescent; Adult; Analgesics, Opioid; Child; Child, Preschool; Cohort Studies; Female; Humans; Hyperalgesia; Male; Middle Aged; Pain Measurement; Piperidines; Postoperative Period; Remifentanil; Risk Factors; Young Adult | 2011 |
Nitrous oxide (N(2)O) reduces postoperative opioid-induced hyperalgesia after remifentanil-propofol anaesthesia in humans.
Topics: Adolescent; Adult; Analgesics, Opioid; Anesthetics, Intravenous; Female; Humans; Hyperalgesia; Lidocaine; Male; Middle Aged; Nitrous Oxide; Pain, Postoperative; Piperidines; Propofol; Prospective Studies; Remifentanil | 2011 |
Intravenous infusion of remifentanil induces transient withdrawal hyperalgesia depending on administration duration in rats.
Topics: Analgesics, Opioid; Animals; Drug Administration Schedule; Hyperalgesia; Infusions, Intravenous; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Pain Measurement; Pain Threshold; Phosphorylation; Piperidines; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Reaction Time; Remifentanil; Time Factors | 2012 |
Effects of surgery and/or remifentanil administration on the expression of pERK1/2, c-Fos and dynorphin in the dorsal root ganglia in mice.
Topics: Analgesics, Opioid; Animals; Behavior, Animal; Dynorphins; Enkephalins; Ganglia, Spinal; Hyperalgesia; Male; Mice; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Pain, Postoperative; Piperidines; Protein Precursors; Proto-Oncogene Proteins c-fos; Remifentanil; RNA, Messenger | 2012 |
Erasure of a spinal memory trace of pain by a brief, high-dose opioid administration.
Topics: Analgesics, Opioid; Animals; Calcium Signaling; Evoked Potentials; Hyperalgesia; Long-Term Potentiation; Male; Naloxone; Nerve Fibers, Unmyelinated; Nociceptive Pain; Phosphorylation; Piperidines; Protein Kinase C; Protein Phosphatase 1; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Opioid, mu; Remifentanil; Sciatic Nerve; Somatostatin; Spinal Cord; Synapses | 2012 |
Dexmedetomidine prevents remifentanil-induced postoperative hyperalgesia and decreases spinal tyrosine phosphorylation of N-methyl-d-aspartate receptor 2B subunit.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Blotting, Western; Dexmedetomidine; Disease Models, Animal; Hyperalgesia; Male; Pain, Postoperative; Phosphorylation; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Remifentanil; Spinal Cord; Tyrosine | 2012 |
Vanguard research in opioid-induced hyperalgesia - but guard the basics.
Topics: Analgesics; Humans; Hyperalgesia; Male; Piperidines; Propranolol; Remifentanil | 2012 |
[Changes of glycogen synthase kinase-3β and its phosphorylation in spinal cord neurons in rats with incisional pain-remifentanil-induced hyperalgesia].
Topics: Animals; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hyperalgesia; Male; Phosphorylation; Piperidines; Rats; Rats, Sprague-Dawley; Remifentanil; Spinal Cord; Spinal Nerves | 2012 |
The effects of gabapentin on acute opioid tolerance to remifentanil under sevoflurane anesthesia in rats.
Topics: Adjuvants, Anesthesia; Amines; Analgesics, Opioid; Anesthesia, General; Anesthetics, Inhalation; Animals; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Gabapentin; gamma-Aminobutyric Acid; Hyperalgesia; Male; Methyl Ethers; Pain Threshold; Piperidines; Rats; Rats, Wistar; Remifentanil; Sevoflurane; Time Factors | 2012 |
High-dose remifentanil prevents development of thermal hyperalgesia in a neuropathic pain model.
Topics: Analgesics, Opioid; Animals; Area Under Curve; Behavior, Animal; Cold Temperature; Data Interpretation, Statistical; Hot Temperature; Hyperalgesia; Male; Neuralgia; Pain, Postoperative; Physical Stimulation; Piperidines; Rats; Rats, Sprague-Dawley; Remifentanil; Spinal Nerves | 2013 |
Glycogen synthase kinase-3β contributes to remifentanil-induced postoperative hyperalgesia via regulating N-methyl-D-aspartate receptor trafficking.
Topics: Analgesics, Opioid; Animals; Blotting, Western; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hot Temperature; Hyperalgesia; Male; Pain, Postoperative; Physical Stimulation; Piperidines; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Receptors, N-Methyl-D-Aspartate; Remifentanil; RNA, Messenger; Spinal Cord; Thiadiazoles | 2013 |
Glial cell activation in the spinal cord and dorsal root ganglia induced by surgery in mice.
Topics: Anesthetics, Intravenous; Animals; Astrocytes; Behavior, Animal; Ganglia, Spinal; Hyperalgesia; Male; Mice; Pain, Postoperative; Piperidines; Remifentanil; Spinal Cord | 2013 |
[Increase in bispectral index induced by antihyperalgesic dose of ketamine].
Topics: Aged; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, Intravenous; Electroencephalography; Female; Humans; Hyperalgesia; Isoflurane; Ketamine; Male; Pain, Postoperative; Piperidines; Propofol; Prostatectomy; Prosthesis Implantation; Remifentanil | 2004 |
The novel analgesic, F 13640, produces intra- and postoperative analgesia in a rat model of surgical pain.
Topics: Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Anesthetics, Inhalation; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Isoflurane; Male; Monitoring, Intraoperative; Orthopedic Procedures; Pain; Pain Measurement; Pain Threshold; Pain, Postoperative; Piperazines; Piperidines; Pulmonary Alveoli; Pyridines; Rats; Rats, Sprague-Dawley; Remifentanil; Serotonin Antagonists; Vocalization, Animal | 2005 |
[Comparison of the suppressive effects of tramadol and low-dose ketamine on the patients with postoperative hyperalgesia after remifentanil-based anaesthesia].
Topics: Adult; Analgesics, Opioid; Anesthesia; Humans; Hyperalgesia; Ketamine; Male; Middle Aged; Pain, Postoperative; Piperidines; Postoperative Period; Remifentanil; Tramadol | 2005 |
Opioid-induced hyperalgesia in a murine model of postoperative pain: role of nitric oxide generated from the inducible nitric oxide synthase.
Topics: Analgesics, Opioid; Animals; Fentanyl; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Nitric Oxide; Nitric Oxide Synthase Type II; Pain, Postoperative; Piperidines; Remifentanil; Species Specificity | 2006 |
Opioid-induced hyperalgesia.
Topics: Analgesics; Analgesics, Opioid; Femoral Artery; Fentanyl; Humans; Hyperalgesia; Ketamine; Male; Middle Aged; Morphine; Myocardial Revascularization; Pain, Postoperative; Piperidines; Remifentanil | 2007 |
Opioid-induced hyperalgesia or opioid-withdrawal hyperalgesia?
Topics: Analgesics, Opioid; Humans; Hyperalgesia; Piperidines; Remifentanil; Substance Withdrawal Syndrome | 2007 |
[Acute opiate tolerance and postoperative hyperalgesia after a brief infusion of remifentanil managed with multimodal analgesia].
Topics: Acetaminophen; Adnexal Diseases; Amides; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Drug Resistance; Drug Tolerance; Female; Fentanyl; Humans; Hyperalgesia; Hysterectomy; Ketorolac; Middle Aged; Morphine; Pain, Postoperative; Piperidines; Remifentanil; Ropivacaine | 2008 |
Spinal and peripheral mu opioids and the development of secondary tactile allodynia after thermal injury.
Topics: Administration, Topical; Analgesics, Opioid; Animals; Burns; Hindlimb; Hyperalgesia; Injections, Spinal; Loperamide; Male; Morphine; Naloxone; Narcotic Antagonists; Neural Pathways; Neurons, Afferent; Pain Threshold; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Remifentanil; Spinal Cord; Touch | 2002 |