rehmannic-acid and Plant-Poisoning

rehmannic-acid has been researched along with Plant-Poisoning* in 3 studies

Reviews

1 review(s) available for rehmannic-acid and Plant-Poisoning

ArticleYear
Current ideas on the pathophysiology and treatment of lantana poisoning of ruminants.
    Australian veterinary journal, 1986, Volume: 63, Issue:6

    Lantana poisoning in ruminants results from the ingestion of toxic varieties of the plant Lantana camara, which contain the triterpene acids lantadene A and lantadene B. Poisoning results in intrahepatic cholestasis and the consequences of the liver injury include jaundice, photosensitisation and ruminal stasis. The decreased ruminal motility causes toxic material to be retained in the rumen and continuous absorption of toxins from the rumen maintains the disease. Lantana poisoning can best be treated by preventing further absorption of toxins. This can be achieved by giving a large quantity of activated charcoal into the rumen together with a large volume of a multiple electrolyte solution to stimulate ruminal motility and rehydrate the animal. Treatment for photosensitive dermatitis should also be given.

    Topics: Animals; Cattle; Goats; Oleanolic Acid; Plant Poisoning; Ruminants; Sheep; Triterpenes

1986

Other Studies

2 other study(ies) available for rehmannic-acid and Plant-Poisoning

ArticleYear
Vaccination as a possible means of preventing lantana poisoning.
    Australian veterinary journal, 1988, Volume: 65, Issue:11

    The toxic triterpene acids lantadene A and lantadene B were isolated from Lantana camara and conjugated to bovine serum albumen or haemocyanin. The conjugates were emulsified with complete Freund's adjuvant and injected into sheep and cattle. Vaccinated animals produced antibodies against the toxic compounds. Cholestasis was less severe in vaccinated than in non-vaccinated sheep challenged with a toxic dose of lantana. The results indicated a mild protective effect of vaccination against the hepatotoxic effects of lantana toxins.

    Topics: Animals; Antibodies; Cattle; Cattle Diseases; Oleanolic Acid; Plant Poisoning; Sapogenins; Sheep; Sheep Diseases; Triterpenes; Vaccination

1988
Fragility of erythrocytes in animals affected by lantana poisoning.
    Clinical toxicology, 1981, Volume: 18, Issue:1

    Clinical observations on four male cow calves and three other lantana poisoned animals under field conditions have been made along with hematological studies, including observations on plasma bilirubin content and osmotic fragility of erythrocytes. Four healthy male cow calves served as control. Five clinically advanced cases succumbed within 1 to 10 days of observation. Hematocrit values in four of the seven affected animals were abnormally high. The total plasma bilirubin content in the fatal cases was of the order of 5 to 50 times the normal value while, in calves that recovered, it was not more than 3 times. The osmotic fragility of erythrocytes was measured by the rate of hemolysis in decreasing concentrations of saline. The erythrocytes of normal animals resisted hemolysis till the saline concentration was lowered to 0.60%, and it was complete at the low saline concentration of 0.30%. However, in lantana poisoned animals, hemolysis started even in 0.72% saline and was complete at a saline concentration of 0.44%. The hemolysis curves of animals that died were far removed from the normal, but those of the calves that recovered and the one that died but had the lowest bilirubin content closely approached the normal curve.

    Topics: Animals; Cattle; Cattle Diseases; Erythrocyte Membrane; Erythrocytes; Female; Hemolysis; Male; Oleanolic Acid; Osmotic Fragility; Plant Poisoning; Plants, Toxic; Sapogenins

1981