refludan has been researched along with Liver-Diseases* in 1 studies
1 other study(ies) available for refludan and Liver-Diseases
Article | Year |
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[Heparin-induced thrombocytopenia and liver hemorrhage following polytrauma].
Up to 3% of patients receiving unfractioned heparin develop heparin-induced thrombocytopenia (HIT). We report on a polytrauma patient who developed severe HIT with bilateral pulmonary embolism. Lepirudin treatment resulted initially in rapid improvement. Ten days after discharge the patient complained of abdominal pain. A large subcapsular hepatic hematoma was diagnosed, requiring repeat surgery and ending in secondary sclerosing cholangitis. This process can potentially be avoided by regular tests of lepirudin concentration and coagulation. Topics: Anticoagulants; Aortic Rupture; Blood Coagulation Tests; Cholangiopancreatography, Endoscopic Retrograde; Cholangitis, Sclerosing; Female; Heparin; Hernia, Diaphragmatic, Traumatic; Hirudins; Humans; Liver; Liver Diseases; Middle Aged; Multiple Trauma; Patient Readmission; Platelet Count; Postoperative Complications; Postoperative Hemorrhage; Recombinant Proteins; Reoperation; Thrombocytopenia; Tomography, X-Ray Computed | 2009 |