reamberin has been researched along with Coma* in 3 studies
1 trial(s) available for reamberin and Coma
| Article | Year |
|---|---|
[Mechanism of neuroprotector action of metabolic antihypoxant reamberin in patients with toxicohypoxic encephalopathy].
Based on investigation of a group of patients with heavy forms of sharp poisoning by neurotropic substances, it is established that inclusion if antihypoxant reamberin in intensive treatment of toxicohypoxic encephalopathy leads to a decrease in the depth of central nervous system depression. This is manifested by reduced duration of patient stay in coma and decreased total duration of resuscitation treatment. Improvement of the clinical picture is accompanied by a decrease in lipid peroxidation activity, increase in the level of antioxidant enzymes, and decrease in the level of NR2A auto-antibodies. That is objective evidence of the efficiency of neuroprotective therapy by reamberin. Topics: Adult; Antioxidants; Autoantibodies; Coma; Delirium; Female; Humans; Hypoxia, Brain; Lipid Peroxidation; Male; Meglumine; Neurotoxicity Syndromes; Succinates | 2012 |
2 other study(ies) available for reamberin and Coma
| Article | Year |
|---|---|
[Neuroprotective effects of succinate-containing antihypoxante reamberine in treatment of patients with toxicohypoxic brain injury].
As a result of survey in process of treatment of 60 patients with severe acute poisoning complicated by the toxic-hypoxic brain edema, found that inclusion of reamberin (antihypoxant containing succinate) in basic therapy leads to increase levels of the antioxidant defense system, decrease lipid peroxidation and reduce NR2A titers of autoantibodies. Reduction of degree of toxic-hypoxic encephalopathy promotes improving the clinical course, manifested shortened duration of coma and hospital bad days. Topics: Adult; Antioxidants; Brain Injuries; Coma; Female; Humans; Lipid Peroxidation; Male; Meglumine; Neuroprotective Agents; Neurotoxicity Syndromes; Poisoning; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Succinates | 2012 |
[Correction of tissue hypoxia with reamberin in severe forms of acute intoxication with neurotropic poisons].
Examination and treatment of 66 patients severely intoxicated with neurotropic poisons showed that inclusion of reamberin in combined therapy decreased the degree of tissue hypoxia as apparent from increased oxygen consumption, oxygen utilization index, and arteriovenous oxygen difference. This in turn accelerated recovery of antioxidant protection and lowered activity of lipid peroxidation. The use of reamberin for the treatment of acute neurotropic intoxication improves clinical conditions of the patients by decreasing duration of the comatose state, requirement for intensive therapy, and lethality. Topics: Adult; Antioxidants; Coma; Humans; Hypoxia; Male; Meglumine; Neurotoxicity Syndromes; Succinates | 2010 |