Page last updated: 2024-08-23

razoxane and Neoplasm Metastasis

razoxane has been researched along with Neoplasm Metastasis in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-199023 (60.53)18.7374
1990's10 (26.32)18.2507
2000's4 (10.53)29.6817
2010's1 (2.63)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bosso, G; Ceste, M; de Conciliis, E; Ferrero, G; Ferro, S; Giaretto, L; Lanfranco, C; Manfredi, R; Miglietta, L; Milanese, S; Parello, G; Simoni, C; Testore, F1
Lu, DY; Lu, TR1
Espié, M; Llombart, A; Marty, M; Monnier, A; Rapoport, BL; Stahalova, V1
Green, MD; Ng, R1
Eiter, H; Rhomberg, W; Saely, CH; Schmid, F1
Fu, NW; Huang, KW; Ren, YF1
Cherubino, R; Giraldi, T; Mitri, E; Sava, G1
Finch, M; Hellmann, K; Hutchinson, GE; Li, XT; Pym, BA1
Hellmann, K; Herman, EH; Waravdekar, VS; Witiak, DT1
Bruno, S; Macdonald, JS; Marsoni, S; Penta, J; Poster, DS1
Cummings, FJ; DeWys, W; Gelman, R; Glick, J; Tormey, DC1
Giraldi, T; Sava, G1
Cuman, R; Giraldi, T; Lassiani, L; Nisi, C; Sava, G1
Burleson, GR; Luckert, PH; Pollard, M1
Baker, D; Constable, W; Elkon, D; Rinehart, L1
Eiter, H; Hergan, K; Rhomberg, W; Schneider, B1
Benestad, HB; Grimstad, IA; Haug, IJ; Siebke, EM1
Giraldi, T; Perissin, L; Rapozzi, V; Zorzet, S2
Bastholt, L; Gjedde, SB; Jakobsen, P; Mirza, MR; Mouridsen, HT; Rose, C; Sørensen, B2
Sledge, GW1
Garbisa, S; Giraldi, T; Onisto, M; Perissin, L; Peron, A; Rapozzi, V; Zorzet, S1
Swain, SM1
Marchant, J1
Bellet, RE; Catalano, RB; Creech, RH; Engstrom, PF; Harris, DT1
Ingber, DE; Lazo, JS; Sartorelli, AC1
Goldman, HD; Lee, HJ; Witiak, DT; Zwilling, BS1
Bakowski, MT1
Hill, SA; Sheldon, PW1
Peters, LJ2
Bellet, RE; Catalano, RB; Creech, RH; Engstrom, PF; Mastrangelo, MJ1
Baldwin, RW; Pimm, MV1
Atherton, A1
Hellmann, K; Rhomberg, W1
Giraldi, T; Grill, V; Mallardi, F; Perissin, L; Zorzet, S1
Garattini, S; Spreafico, F1

Reviews

7 review(s) available for razoxane and Neoplasm Metastasis

ArticleYear
Antimetastatic activities and mechanisms of bisdioxopiperazine compounds.
    Anti-cancer agents in medicinal chemistry, 2010, Volume: 10, Issue:7

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Cell Line, Transformed; Fibrinogen; Humans; Mice; Molecular Targeted Therapy; Neoplasm Metastasis; Piperazines; Razoxane

2010
Managing cardiotoxicity in anthracycline-treated breast cancers.
    Expert opinion on drug safety, 2007, Volume: 6, Issue:3

    Topics: Anthracyclines; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Breast Neoplasms; Clinical Trials, Phase III as Topic; Doxorubicin; Female; Heart; Humans; Liposomes; Neoplasm Metastasis; Paclitaxel; Razoxane; Trastuzumab

2007
Biological properties of ICRF-159 and related bis(dioxopiperazine) compounds.
    Advances in pharmacology and chemotherapy, 1982, Volume: 19

    Topics: Animals; Cell Division; Cell Survival; Drug Interactions; Humans; Neoplasm Metastasis; Piperazines; Radiation-Sensitizing Agents; Razoxane; Structure-Activity Relationship

1982
Selective antimetastatic drugs (review).
    Anticancer research, 1981, Volume: 1, Issue:3

    Topics: Animals; Antineoplastic Agents; Hemostasis; Humans; Leukemia; Leukemia, Experimental; Mice; Neoplasm Metastasis; Neoplasms; Neoplasms, Experimental; Protease Inhibitors; Rats; Razoxane

1981
Adult multicenter trials using dexrazoxane to protect against cardiac toxicity.
    Seminars in oncology, 1998, Volume: 25, Issue:4 Suppl 10

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cardiovascular Agents; Dose-Response Relationship, Drug; Doxorubicin; Female; Heart Diseases; Humans; Multicenter Studies as Topic; Neoplasm Metastasis; Randomized Controlled Trials as Topic; Razoxane

1998
Radiotherapeutic enhancement by razoxane.
    Cancer treatment reviews, 1991, Volume: 18, Issue:4

    Topics: Animals; Combined Modality Therapy; Female; Humans; Male; Mice; Neoplasm Metastasis; Neoplasms; Radiation-Sensitizing Agents; Razoxane

1991
Selective antimetastatic treatment--current status and future prospects.
    Cancer treatment reviews, 1974, Volume: 1, Issue:4

    Topics: Animals; Carcinoma, Ehrlich Tumor; Cyclophosphamide; Drug Evaluation, Preclinical; Humans; Immunotherapy; Leukemia L1210; Lung Neoplasms; Lymphatic Metastasis; Mice; Mice, Inbred Strains; Models, Biological; Neoplasm Metastasis; Neoplasm Seeding; Neoplasm Transplantation; Neoplasms, Experimental; Neoplastic Cells, Circulating; Polyethylene Glycols; Rats; Razoxane; Semustine

1974

Trials

8 trial(s) available for razoxane and Neoplasm Metastasis

ArticleYear
Multicenter randomized phase III study of the cardioprotective effect of dexrazoxane (Cardioxane) in advanced/metastatic breast cancer patients treated with anthracycline-based chemotherapy.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2006, Volume: 17, Issue:4

    Topics: Adult; Aged; Anthracyclines; Antineoplastic Agents; Breast Neoplasms; Cardiotonic Agents; Female; Humans; Middle Aged; Neoplasm Metastasis; Razoxane

2006
Combined vindesine and razoxane shows antimetastatic activity in advanced soft tissue sarcomas.
    Clinical & experimental metastasis, 2008, Volume: 25, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; Disease-Free Survival; Humans; Neoplasm Metastasis; Pilot Projects; Radiotherapy; Razoxane; Sarcoma; Soft Tissue Neoplasms; Treatment Outcome; Vindesine

2008
Bis-diketopiperazine derivatives in clinical oncology: ICRF-159.
    Cancer clinical trials, 1980, Volume: 3, Issue:4

    Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Daunorubicin; Doxorubicin; Drug Evaluation; Drug Interactions; Head and Neck Neoplasms; Humans; Lymphoma; Mice; Neoplasm Metastasis; Neoplasms; Piperazines; Razoxane

1980
Adriamycin plus vincristine alone or with dibromodulcitol or ICRF-159 in metastatic breast cancer.
    Cancer clinical trials, 1981,Fall, Volume: 4, Issue:3

    Topics: Aged; Breast Neoplasms; Clinical Trials as Topic; Doxorubicin; Drug Therapy, Combination; Female; Humans; Menopause; Middle Aged; Mitolactol; Neoplasm Metastasis; Piperazines; Razoxane; Time Factors; Vincristine

1981
Inoperable recurrent rectal cancer: results of a prospective trial with radiation therapy and razoxane.
    International journal of radiation oncology, biology, physics, 1994, Sep-30, Volume: 30, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Palliative Care; Prospective Studies; Radiation-Sensitizing Agents; Radiotherapy; Razoxane; Rectal Neoplasms; Survival Rate

1994
The pharmacokinetics of high-dose epirubicin and of the cardioprotector ADR-529 given together with cyclophosphamide, 5-fluorouracil, and tamoxifen in metastatic breast-cancer patients.
    Cancer chemotherapy and pharmacology, 1994, Volume: 35, Issue:1

    Topics: Aged; Analysis of Variance; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Chromatography, High Pressure Liquid; Cyclophosphamide; Drug Administration Schedule; Epirubicin; Fluorouracil; Heart Diseases; Humans; Middle Aged; Neoplasm Metastasis; Razoxane; Tamoxifen

1994
The cardioprotector ADR-529 and high-dose epirubicin given in combination with cyclophosphamide, 5-fluorouracil, and tamoxifen: a phase I study in metastatic breast cancer.
    Cancer chemotherapy and pharmacology, 1994, Volume: 34, Issue:5

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cohort Studies; Combined Modality Therapy; Cyclophosphamide; Dose-Response Relationship, Drug; Epirubicin; Female; Fluorouracil; Humans; Infusions, Intravenous; Middle Aged; Neoplasm Metastasis; Razoxane; Tamoxifen

1994
Phase II study of ICRF-159 in refractory metastatic breast cancer.
    Cancer treatment reports, 1979, Volume: 63, Issue:1

    Topics: Blood Cell Count; Breast Neoplasms; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Neoplasm Metastasis; Piperazines; Razoxane; Time Factors

1979

Other Studies

23 other study(ies) available for razoxane and Neoplasm Metastasis

ArticleYear
Cardioprotective effect of dexrazoxane in patients with breast cancer treated with anthracyclines in adjuvant setting: a 10-year single institution experience.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2008, Volume: 8, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cardiovascular Agents; Dose-Response Relationship, Drug; Doxorubicin; Electrocardiography; Epirubicin; Female; Follow-Up Studies; Heart Failure; Humans; Incidence; Life Expectancy; Middle Aged; Neoplasm Metastasis; Razoxane; Retrospective Studies

2008
[Effects of bimolane on size, metastases and cyclic AMP levels of Lewis lung carcinoma].
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1984, Volume: 5, Issue:1

    Topics: Animals; Antineoplastic Agents; Cyclic AMP; Female; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Metastasis; Piperazines; Razoxane

1984
Hemostasis and mechanism of action of selective antimetastatic drugs in mice bearing Lewis lung carcinoma.
    European journal of cancer & clinical oncology, 1984, Volume: 20, Issue:7

    Topics: Animals; Antineoplastic Agents; Blood Coagulation; Blood Coagulation Tests; Cyclophosphamide; Dacarbazine; Female; Fibrinogen; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasm Metastasis; Piperazines; Platelet Aggregation; Platelet Count; Razoxane; Triazenes

1984
Effect of AT1727 on growth and metastasis of murine tumours.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:2

    Topics: Animals; Antineoplastic Agents; Drug Administration Schedule; Female; Leukemia L1210; Lung Neoplasms; Lymphoma; Male; Melanoma; Mice; Neoplasm Metastasis; Neoplasms, Experimental; Piperazines; Razoxane; Sarcoma 180

1983
Selectivity of the antimetastatic and cytotoxic effects of 1-p-(3,3-dimethyl-1-triazeno)benzoic acid potassium salt (+/-)-1,2-di(3,5-dioxopiperazin-1-yl)propane, and cyclophosphamide in mice bearing Lewis lung carcinoma.
    Cancer research, 1981, Volume: 41, Issue:6

    Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Lung Neoplasms; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Neoplastic Cells, Circulating; Piperazines; Razoxane; Thymidine; Time Factors; Triazenes

1981
Interference with in vivo growth and metastasis of prostate adenocarcinoma (PA-III) by ICRF-159.
    The Prostate, 1981, Volume: 2, Issue:1

    Topics: Adenocarcinoma; Animals; Cell Division; Lymph Nodes; Lymphatic Metastasis; Male; Neoplasm Metastasis; Neoplasms, Experimental; Piperazines; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Razoxane

1981
The influence of ICRF-159 and levamisole on the incidence of metastases following local irradiation of a solid tumor.
    Cancer, 1981, Nov-15, Volume: 48, Issue:10

    Topics: Animals; Female; Levamisole; Mice; Neoplasm Metastasis; Neoplasm Recurrence, Local; Neoplasms; Neoplasms, Radiation-Induced; Piperazines; Radiotherapy; Radiotherapy Dosage; Razoxane; Risk

1981
Simultaneous assessment of migration and proliferation of murine fibrosarcoma cells, as affected by hydroxyurea, vinblastine, cytochalasin B, Razoxane and interferon.
    Cell proliferation, 1993, Volume: 26, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Division; Cell Movement; Chemotaxis; Cytochalasin B; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Humans; Hydroxyurea; Interferons; Leukocytes; Mice; Neoplasm Metastasis; Razoxane; Tumor Cells, Cultured; Vinblastine

1993
Rotational stress reduces the effectiveness of antitumor drugs in mice.
    Annals of the New York Academy of Sciences, 1994, Nov-25, Volume: 741

    Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Drug Resistance; Female; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Neuroimmunomodulation; Razoxane; Rotation; Stress, Physiological

1994
Paclitaxel doublets in metastatic breast cancer: Eastern Cooperative Oncology Group and Hoosier Oncology Group Studies.
    Seminars in oncology, 1996, Volume: 23, Issue:5 Suppl 11

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cardiovascular Agents; Cisplatin; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Doxorubicin; Female; Heart; Humans; Multicenter Studies as Topic; Neoplasm Metastasis; Paclitaxel; Pilot Projects; Prospective Studies; Randomized Controlled Trials as Topic; Razoxane

1996
Suppression of metastatic potential and up-regulation of gelatinases and uPA in LLC by protracted in vivo treatment with dacarbazine or razoxane.
    International journal of cancer, 1997, Sep-17, Volume: 72, Issue:6

    Topics: Animals; Collagenases; Dacarbazine; Gelatinases; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Immunosuppression Therapy; Lung Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Metalloendopeptidases; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Razoxane; RNA, Messenger; Transcription, Genetic; Urokinase-Type Plasminogen Activator

1997
Prophylactic chemotherapy following breast cancer: a personal experience.
    Nursing times, 1977, Jul-07, Volume: 73, Issue:27

    Topics: Adenocarcinoma; Adenocarcinoma, Scirrhous; Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Female; Humans; Levodopa; Neoplasm Metastasis; Razoxane; Tamoxifen

1977
Enhancement of experimental lung metastases by cultured B16 melanoma cells treated with (+/-)-1,2-bis(3,5-dioxopiperazin-1-y)propane (ICRF-159).
    Cancer research, 1978, Volume: 38, Issue:8

    Topics: Animals; Cell Division; Cell Survival; Female; Glycosaminoglycans; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Piperazines; Razoxane; Transplantation, Isogeneic

1978
Stereoselective effects of cis- and trans-cyclopropylbis (dioxopiperazines) related to ICRF-159 on metastases of hamster lung adenocarcinoma.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:12

    Topics: Adenocarcinoma; Animals; Cricetinae; Lung Neoplasms; Male; Mesocricetus; Molecular Conformation; Neoplasm Metastasis; Neoplasms, Experimental; Piperazines; Razoxane; Structure-Activity Relationship

1978
ICRF 159, (+/-) 1,2-di(3,5-dioxopiperazin-1-yl) propane NSC-129,943; razoxane.
    Cancer treatment reviews, 1976, Volume: 3, Issue:2

    Topics: Animals; Antineoplastic Agents; Cricetinae; Dogs; Drug Synergism; Haplorhini; Humans; Immunosuppressive Agents; Leukemia; Neoplasm Metastasis; Neoplasms; Piperazines; Rabbits; Radiation-Sensitizing Agents; Rats; Razoxane; Teratogens

1976
Hypoxic cell radiosensitizers and local control by X-ray of a transplanted tumour in mice.
    British journal of cancer, 1977, Volume: 35, Issue:6

    Topics: Animals; Hypoxia; Metronidazole; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Nitrofurans; Nitroimidazoles; Radiation-Sensitizing Agents; Radiotherapy Dosage; Razoxane; Regeneration; Transplantation, Homologous

1977
Modification of the radiocurability of a syngeneic murine squamous carcinoma by its site of growth, by electron-affinic drugs, and by ICRF 159.
    The British journal of radiology, 1976, Volume: 49, Issue:584

    Topics: Animals; Carcinoma, Squamous Cell; Dose-Response Relationship, Radiation; Female; Imidazoles; Metronidazole; Mice; Mice, Inbred Strains; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Oxygen; Radiation-Sensitizing Agents; Razoxane; Skin Neoplasms; Transplantation, Homologous

1976
Phase II study of ICRF-159 in patients with metastatic colorectal carcinoma previously exposed to systemic chemotherapy.
    Cancer treatment reports, 1976, Volume: 60, Issue:9

    Topics: Adult; Aged; Colonic Neoplasms; Female; Humans; Male; Middle Aged; Neoplasm Metastasis; Piperazines; Razoxane; Rectal Neoplasms

1976
Influence of ICRF 159 and trition WR 1339 on metastases of a rat epithelioma.
    British journal of cancer, 1975, Volume: 31, Issue:1

    Topics: Animals; Female; Lung Neoplasms; Neoplasm Metastasis; Neoplasms, Experimental; Piperazines; Polyethylene Glycols; Quaternary Ammonium Compounds; Rats; Razoxane

1975
The effect of (+/-) 1,2-bis(3,5-dioxopiperazin-1-yl) propane (ICRF 159) on liver metastases from a hamster lymphoma.
    European journal of cancer, 1975, Volume: 11, Issue:6

    Topics: Animals; Blood Vessels; Cricetinae; Liver; Liver Neoplasms; Lymphoma, Non-Hodgkin; Neoplasm Metastasis; Neoplasms, Experimental; Piperazines; Razoxane

1975
A study of the influence of various diagnostic and therapeutic procedures applied to a murine squamous carcinoma on its metastatic behaviour.
    British journal of cancer, 1975, Volume: 32, Issue:3

    Topics: Animals; Biopsy; Carcinoma, Squamous Cell; Disease Models, Animal; Female; Humans; Immunization; Lymph Node Excision; Mice; Mice, Inbred Strains; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Razoxane; Transplantation, Isogeneic

1975
Role of immune and/or natural factors of resistance of the host to tumor progression on the effectiveness of antitumor treatment.
    Pharmacological research, 1992, Volume: 26 Suppl 2

    Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Female; Mice; Mice, Inbred Strains; Neoplasm Metastasis; Neoplasms, Experimental; Razoxane

1992
Morphological analysis of metastatic potential and antimetastatic drug effects in mice bearing two lines of Lewis lung carcinoma.
    Clinical & experimental metastasis, 1987, Volume: 5, Issue:3

    Topics: Animals; Dacarbazine; Hemorrhage; Lung Neoplasms; Mice; Neoplasm Metastasis; Piperazines; Razoxane; Triazenes

1987