razoxane has been researched along with Lung Neoplasms in 44 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 29 (65.91) | 18.7374 |
1990's | 6 (13.64) | 18.2507 |
2000's | 7 (15.91) | 29.6817 |
2010's | 2 (4.55) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Cao, J; Chen, L; He, L; Li, H; Li, L; Li, Y; Liu, M; Lu, Q; Lv, D; Wu, D; Xie, F | 1 |
Sabisz, M; Skladanowski, A | 1 |
Bahrami, A; Davidoff, AM; Fernandez-Pineda, I; Green, JF; McGregor, LM; Sandoval, JA | 1 |
Hasinoff, BB; Hofland, KF; Jensen, PB; Langer, SW; Schroeder, PE; Sehested, M | 2 |
Ding, J; Lu, DY; Xu, B | 1 |
Bast, A; den Hartog, GJ; Kaiserová, H; Kvasnicková, E; Schröterová, L; Simůnek, T | 1 |
Aldieri, E; Betta, PG; Bosia, A; Doublier, S; Gazzano, E; Ghigo, D; Orecchia, S; Riganti, C | 1 |
Byfield, JE; Clamon, GH; Corder, MP; Herbst, KD; Leimert, JT; Platz, CE; Tewfik, HH | 1 |
Fu, NW; Huang, KW; Ren, YF | 1 |
Liu, TF; Zhang, XF; Zhang, ZY | 1 |
Bricker, L; Liepman, MK; Natale, RB; Sauder, A; Wheeler, RH | 1 |
Clauw, DJ; Natale, RB; Ruddon, RW; Wheeler, RH | 1 |
Cherubino, R; Giraldi, T; Mitri, E; Sava, G | 1 |
Finch, M; Hellmann, K; Hutchinson, GE; Li, XT; Pym, BA | 1 |
Campbell, ED; Carter, WH; Stablein, DM; Wampler, GL | 1 |
Fair, WR; Heston, WD; Kadmon, D; Lazan, DW | 1 |
Fair, WR; Heston, WD; Kadmon, D | 3 |
Cuman, R; Giraldi, T; Lassiani, L; Nisi, C; Sava, G | 1 |
Campolito, LB; George, T; Reiches, NA; Witiak, DT; Zwilling, BS | 1 |
Giraldi, T; Perissin, L; Rapozzi, V; Zorzet, S | 1 |
Chen, RT; Lu, DY; Xu, B; Zhang, X | 1 |
Jensen, PB; Sehested, M | 1 |
Garbisa, S; Giraldi, T; Onisto, M; Perissin, L; Peron, A; Rapozzi, V; Zorzet, S | 1 |
Grass, M; Rhomberg, W | 1 |
Falck, J; Jensen, LH; Jensen, PB; Nitiss, JL; Roerth, M; Rose, A; Sehested, M; Wessel, I | 1 |
Jensen, LH; Jensen, PB; Nitiss, JL; Renodon-Corniere, A; Sehested, M; Sorensen, TK; Wessel, I | 1 |
Carr, DT; Coles, DT; Eagan, RT; Frytak, S; Rubin, J | 1 |
Burholt, DR; Evans, MJ; Kovacs, CJ; Schenken, LL | 2 |
Davies, BM; Watling, DC | 1 |
Casazza, AM; Di Marco, A; Giuliani, F; Savi, G | 1 |
Burholt, DR; Kovacs, CJ; Schenken, LL | 1 |
Bellet, RE; Muggia, FM; Penta, JS; Rozencweig, M; Von Hoff, DD; Wasserman, TH | 1 |
Ingber, DE; Lazo, JS; Sartorelli, AC | 1 |
Goldman, HD; Lee, HJ; Witiak, DT; Zwilling, BS | 1 |
Baldwin, RW; Pimm, MV | 1 |
Giraldi, T; Grill, V; Mallardi, F; Perissin, L; Zorzet, S | 1 |
De-Oliveira, MM; Giannotti Filho, O; Joussef, AC; Nakamura, IT | 1 |
Otter, GM; Ren, YF; Schmid, FA | 1 |
Cox, R; Ford, CH; Johnson, JR; Jones, DR; Newman, CE; Wheaton, M | 1 |
Garattini, S; Spreafico, F | 1 |
3 review(s) available for razoxane and Lung Neoplasms
Article | Year |
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Isolated subcutaneous metastasis of osteosarcoma 5 years after initial diagnosis.
Topics: Abdominal Wall; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Calcinosis; Cisplatin; Combined Modality Therapy; Doxorubicin; Female; Humans; Ifosfamide; Lung Neoplasms; Methotrexate; Neoadjuvant Therapy; Organ Sparing Treatments; Osteosarcoma; Radiography; Razoxane; Receptor, IGF Type 1; Skin Neoplasms; Subcutaneous Tissue; Tibia; Time Factors; Young Adult | 2011 |
[Angiosarcoma of the right atrium: local control via low radiation doses and razoxane. A case report].
Topics: Aged; Antineoplastic Agents; Chemotherapy, Adjuvant; Fatal Outcome; Heart Atria; Heart Neoplasms; Hemangiosarcoma; Humans; Liver Neoplasms; Lung Neoplasms; Male; Neoplasm Recurrence, Local; Radiotherapy Dosage; Radiotherapy, Adjuvant; Razoxane | 1999 |
Selective antimetastatic treatment--current status and future prospects.
Topics: Animals; Carcinoma, Ehrlich Tumor; Cyclophosphamide; Drug Evaluation, Preclinical; Humans; Immunotherapy; Leukemia L1210; Lung Neoplasms; Lymphatic Metastasis; Mice; Mice, Inbred Strains; Models, Biological; Neoplasm Metastasis; Neoplasm Seeding; Neoplasm Transplantation; Neoplasms, Experimental; Neoplastic Cells, Circulating; Polyethylene Glycols; Rats; Razoxane; Semustine | 1974 |
5 trial(s) available for razoxane and Lung Neoplasms
Article | Year |
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Pharmacokinetics of etoposide in cancer patients treated with high-dose etoposide and with dexrazoxane (ICRF-187) as a rescue agent.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Brain Neoplasms; Carcinoma, Small Cell; Catheters, Indwelling; Chromatography, High Pressure Liquid; Etoposide; Humans; Infusions, Intravenous; Lung Neoplasms; Razoxane | 2004 |
Radiotherapy plus razoxane for advanced limited extent carcinoma of the lung.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Blood Cell Count; Carcinoma, Small Cell; Carcinoma, Squamous Cell; Child; Child, Preschool; Clinical Trials as Topic; Combined Modality Therapy; Drug Administration Schedule; Esophagitis; Female; Humans; Lung Neoplasms; Male; Middle Aged; Piperazines; Pneumonia; Radiation Injuries; Random Allocation; Razoxane | 1984 |
Preliminary report on AT1727 as a potential radiosensitizer.
Topics: Clinical Trials as Topic; Combined Modality Therapy; Humans; Lung Neoplasms; Neoplasms; Piperazines; Radiation-Sensitizing Agents; Random Allocation; Razoxane; Sarcoma; Soft Tissue Neoplasms | 1984 |
ICRF-159 versus polychemotherapy in non-small cell lung cancer.
Topics: Adult; Aged; Bleomycin; Carcinoma; Doxorubicin; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Male; Middle Aged; Piperazines; Prognosis; Razoxane; Vincristine | 1976 |
Reduced survival with radiotherapy and razoxane compared with radiotherapy alone for inoperable lung cancer in a randomised double-blind trial.
Topics: Clinical Trials as Topic; Combined Modality Therapy; Double-Blind Method; Humans; Lung Neoplasms; Piperazines; Razoxane | 1985 |
36 other study(ies) available for razoxane and Lung Neoplasms
Article | Year |
---|---|
PAK1-cofilin phosphorylation mediates human lung adenocarcinoma cells migration induced by apelin-13.
Topics: Actin Depolymerizing Factors; Adenocarcinoma; Adenocarcinoma of Lung; Apelin Receptors; Cell Hypoxia; Cell Line, Tumor; Cell Movement; Dose-Response Relationship, Drug; Doxorubicin; Gene Expression Regulation, Neoplastic; Humans; Intercellular Signaling Peptides and Proteins; Lung Neoplasms; p21-Activated Kinases; Phosphorylation; Razoxane; Receptors, G-Protein-Coupled; Signal Transduction; Time Factors | 2016 |
Cancer stem cells and escape from drug-induced premature senescence in human lung tumor cells: implications for drug resistance and in vitro drug screening models.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Caffeine; Cell Cycle Proteins; Cell Line, Tumor; Cellular Senescence; DNA Damage; DNA-Binding Proteins; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; Neoplastic Stem Cells; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Razoxane; Tumor Suppressor Proteins | 2009 |
Metabolism of dexrazoxane (ICRF-187) used as a rescue agent in cancer patients treated with high-dose etoposide.
Topics: Aged; Antineoplastic Agents, Phytogenic; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Ethylenediamines; Etoposide; Female; Glycine; Half-Life; Humans; Infusions, Intravenous; Lung Neoplasms; Male; Middle Aged; Razoxane | 2003 |
Antitumor effects of two bisdioxopiperazines against two experimental lung cancer models in vivo.
Topics: Animals; Antineoplastic Agents; Carcinoma, Lewis Lung; China; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Razoxane; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2004 |
Iron is not involved in oxidative stress-mediated cytotoxicity of doxorubicin and bleomycin.
Topics: Aldehydes; Antibiotics, Antineoplastic; Apoptosis; Bleomycin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deferoxamine; Doxorubicin; Electron Spin Resonance Spectroscopy; Free Radicals; Humans; Hydrazones; Hydrogen Peroxide; Iron; Iron Chelating Agents; Iron Compounds; Isoniazid; Lipid Peroxidation; Lung Neoplasms; Oxidative Stress; Pyridoxal; Razoxane; Time Factors | 2006 |
Asbestos induces doxorubicin resistance in MM98 mesothelioma cells via HIF-1alpha.
Topics: Antineoplastic Agents; Asbestos; Asbestos, Crocidolite; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Doxorubicin; Drug Resistance, Neoplasm; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Iron; Lung; Lung Neoplasms; Mesothelioma; Razoxane | 2008 |
[Effects of bimolane on size, metastases and cyclic AMP levels of Lewis lung carcinoma].
Topics: Animals; Antineoplastic Agents; Cyclic AMP; Female; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Metastasis; Piperazines; Razoxane | 1984 |
Phase II trial of ICRF-187 in non-small cell lung cancer.
Topics: Adult; Aged; Bone Marrow; Drug Evaluation; Female; Humans; Leukocyte Count; Lung Neoplasms; Male; Middle Aged; Piperazines; Platelet Count; Razoxane; Stereoisomerism | 1983 |
The cytokinetic and cytotoxic effects of ICRF-159 and ICRF-187 in vitro and ICRF-187 in human bone marrow in vivo.
Topics: Antineoplastic Agents; Bone Marrow Cells; Bone Neoplasms; Burkitt Lymphoma; Cell Cycle; Cell Division; Cell Survival; Cells, Cultured; Drug Evaluation; Humans; Kinetics; Lung Neoplasms; Mitosis; Piperazines; Razoxane; Stereoisomerism; Thymidine | 1983 |
Hemostasis and mechanism of action of selective antimetastatic drugs in mice bearing Lewis lung carcinoma.
Topics: Animals; Antineoplastic Agents; Blood Coagulation; Blood Coagulation Tests; Cyclophosphamide; Dacarbazine; Female; Fibrinogen; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasm Metastasis; Piperazines; Platelet Aggregation; Platelet Count; Razoxane; Triazenes | 1984 |
Effect of AT1727 on growth and metastasis of murine tumours.
Topics: Animals; Antineoplastic Agents; Drug Administration Schedule; Female; Leukemia L1210; Lung Neoplasms; Lymphoma; Male; Melanoma; Mice; Neoplasm Metastasis; Neoplasms, Experimental; Piperazines; Razoxane; Sarcoma 180 | 1983 |
Drug activity and therapeutic synergism in cancer treatment.
Topics: Animals; Antineoplastic Agents; Dacarbazine; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Female; Fluorouracil; Humans; Hydroxamic Acids; Lung Neoplasms; Male; Melanoma; Mice; Mitomycin; Mitomycins; Neoplasms; Neoplasms, Experimental; Rats; Razoxane; Teniposide | 1982 |
Inhibition of the R3327MAT-Lu prostatic tumor by diethylstilbestrol and 1,2-bis(3,5-dioxopiperazin-1-yl)propane.
Topics: Animals; Antineoplastic Agents; Diethylstilbestrol; DNA, Neoplasm; Lung Neoplasms; Male; Neoplasms, Experimental; Piperazines; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Razoxane | 1982 |
Treatment of a metastatic prostate derived tumor with surgery and chemotherapy.
Topics: Animals; Cyclophosphamide; Doxorubicin; Lung Neoplasms; Male; Neoplasms, Experimental; Prostatic Neoplasms; Rats; Razoxane | 1982 |
Selectivity of the antimetastatic and cytotoxic effects of 1-p-(3,3-dimethyl-1-triazeno)benzoic acid potassium salt (+/-)-1,2-di(3,5-dioxopiperazin-1-yl)propane, and cyclophosphamide in mice bearing Lewis lung carcinoma.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Lung Neoplasms; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Neoplastic Cells, Circulating; Piperazines; Razoxane; Thymidine; Time Factors; Triazenes | 1981 |
Effect of stereoisomers related to ICRF-159 on metastasis of B16 melanoma.
Topics: Animals; Cell Division; Cell Line; Cell Survival; Lung Neoplasms; Male; Melanoma; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Piperazines; Razoxane; Stereoisomerism | 1981 |
Effect of surgery and adjuvant chemotherapy on the R3327 MAT-Ly Lu tumor.
Topics: Animals; Lung Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Male; Piperazines; Prostatic Neoplasms; Rats; Rats, Inbred Strains; Razoxane | 1981 |
Effect of high dose diethylstilbestrol and ICRF-159 on the growth and metastases of the R3327 MAT-LyLu prostate-derived tumor.
Topics: Animals; Diethylstilbestrol; Lung Neoplasms; Lymphatic Metastasis; Male; Neoplasms, Experimental; Piperazines; Prostatic Neoplasms; Rats; Razoxane; Thymidine | 1981 |
Rotational stress reduces the effectiveness of antitumor drugs in mice.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Drug Resistance; Female; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Neuroimmunomodulation; Razoxane; Rotation; Stress, Physiological | 1994 |
[Distribution of 14C labeled at dioxopiperazine or methyl morpholine group of probimane by whole body autoradiography].
Topics: Animals; Antineoplastic Agents; Autoradiography; Carbon Radioisotopes; Humans; Leukemia L1210; Lung Neoplasms; Mice; Mice, Nude; Razoxane; Tissue Distribution | 1993 |
Mapping of DNA topoisomerase II poisons (etoposide, clerocidin) and catalytic inhibitors (aclarubicin, ICRF-187) to four distinct steps in the topoisomerase II catalytic cycle.
Topics: Aclarubicin; Blotting, Western; Diterpenes; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Etoposide; Humans; Lung Neoplasms; Razoxane; Tumor Cells, Cultured | 1996 |
Suppression of metastatic potential and up-regulation of gelatinases and uPA in LLC by protracted in vivo treatment with dacarbazine or razoxane.
Topics: Animals; Collagenases; Dacarbazine; Gelatinases; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Immunosuppression Therapy; Lung Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Metalloendopeptidases; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Razoxane; RNA, Messenger; Transcription, Genetic; Urokinase-Type Plasminogen Activator | 1997 |
Human small cell lung cancer NYH cells selected for resistance to the bisdioxopiperazine topoisomerase II catalytic inhibitor ICRF-187 demonstrate a functional R162Q mutation in the Walker A consensus ATP binding domain of the alpha isoform.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Amino Acid Substitution; Amsacrine; Animals; Antineoplastic Agents; Binding Sites; Carcinoma, Small Cell; Catalysis; CHO Cells; Consensus Sequence; Cricetinae; Cricetulus; DNA Damage; DNA Mutational Analysis; DNA Topoisomerases, Type II; DNA, Neoplasm; DNA, Single-Stranded; Drug Resistance, Neoplasm; Enzyme Inhibitors; Etoposide; Humans; Lung Neoplasms; Molecular Sequence Data; Mutagenesis, Site-Directed; Point Mutation; Protein Isoforms; Razoxane; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Structure-Activity Relationship; Thiobarbiturates; Topoisomerase II Inhibitors; Tumor Stem Cell Assay | 1999 |
Human small cell lung cancer NYH cells resistant to the bisdioxopiperazine ICRF-187 exhibit a functional dominant Tyr165Ser mutation in the Walker A ATP binding site of topoisomerase II alpha.
Topics: Adenosine Triphosphate; Amino Acid Substitution; Antigens, Neoplasm; Antineoplastic Agents; Binding Sites; Carcinoma, Small Cell; Cell Division; DNA Topoisomerases, Type II; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Fungal; Drug Resistance, Neoplasm; Genotype; Humans; Lung Neoplasms; Mutation; Protein Binding; Razoxane; Saccharomyces cerevisiae; Transformation, Genetic; Tumor Cells, Cultured | 2002 |
ICRF-159 enhancement of radiation response in combined modality therapies. I. Time/dose relationships for tumour response.
Topics: Animals; Drug Administration Schedule; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Piperazines; Radiation-Sensitizing Agents; Razoxane; Time Factors | 1979 |
ICRF-159 enhancement of radiation response in combined modality therapies. II. Differential responses of tumour and normal tissues.
Topics: Animals; Cell Division; Drug Administration Schedule; Intestinal Mucosa; Jejunum; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Piperazines; Radiation-Sensitizing Agents; Razoxane | 1979 |
Radiosensitization of pulmonary metastases-I. In vivo testing of hycanthone, insulin and razoxane.
Topics: Animals; Hycanthone; Insulin; Lung Neoplasms; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Piperazines; Radiation-Sensitizing Agents; Razoxane; Thioxanthenes; Transplantation, Homologous | 1979 |
Combination chemotherapy and surgical adjuvant chemotherapy on MS-2 sarcoma and lung metastases in mice.
Topics: Animals; Antineoplastic Agents; Cyclophosphamide; Disease Models, Animal; Doxorubicin; Drug Therapy, Combination; Lung Neoplasms; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Razoxane; Sarcoma, Experimental; Time Factors; Transplantation, Isogeneic | 1979 |
Therapeutic potentiation of combined cis-dichlorodiammineplatinum (II) and irradiation by ICRF-159.
Topics: Animals; Cell Cycle; Cell Division; Cisplatin; Drug Synergism; Drug Therapy, Combination; Lung Neoplasms; Male; Mice; Neoplasms, Experimental; Piperazines; Radiation-Sensitizing Agents; Razoxane; Time Factors | 1979 |
ICRF-159: current status and clinical prospects.
Topics: Alopecia; Animals; Colonic Neoplasms; Humans; Leukopenia; Lung Neoplasms; Lymphoma; Melanoma; Mice; Nausea; Neoplasms, Experimental; Piperazines; Razoxane; Rectal Neoplasms; Sarcoma | 1977 |
Enhancement of experimental lung metastases by cultured B16 melanoma cells treated with (+/-)-1,2-bis(3,5-dioxopiperazin-1-y)propane (ICRF-159).
Topics: Animals; Cell Division; Cell Survival; Female; Glycosaminoglycans; Lung Neoplasms; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Piperazines; Razoxane; Transplantation, Isogeneic | 1978 |
Stereoselective effects of cis- and trans-cyclopropylbis (dioxopiperazines) related to ICRF-159 on metastases of hamster lung adenocarcinoma.
Topics: Adenocarcinoma; Animals; Cricetinae; Lung Neoplasms; Male; Mesocricetus; Molecular Conformation; Neoplasm Metastasis; Neoplasms, Experimental; Piperazines; Razoxane; Structure-Activity Relationship | 1978 |
Influence of ICRF 159 and trition WR 1339 on metastases of a rat epithelioma.
Topics: Animals; Female; Lung Neoplasms; Neoplasm Metastasis; Neoplasms, Experimental; Piperazines; Polyethylene Glycols; Quaternary Ammonium Compounds; Rats; Razoxane | 1975 |
Morphological analysis of metastatic potential and antimetastatic drug effects in mice bearing two lines of Lewis lung carcinoma.
Topics: Animals; Dacarbazine; Hemorrhage; Lung Neoplasms; Mice; Neoplasm Metastasis; Piperazines; Razoxane; Triazenes | 1987 |
Intratumor chemotherapy in combination with a systemic antimetastatic drug in the treatment of Lewis-lung carcinoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carmustine; Chromans; Injections; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Polymers; Razoxane | 1985 |
Further evaluation of bimolane and analogs as potential antitumor agents.
Topics: Animals; Drug Resistance; Female; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Osteosarcoma; Piperazines; Razoxane; Sarcoma 180 | 1985 |