Page last updated: 2024-08-23

razoxane and Heart Failure

razoxane has been researched along with Heart Failure in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.57)18.7374
1990's10 (35.71)18.2507
2000's11 (39.29)29.6817
2010's6 (21.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brower, V1
Bosso, G; Ceste, M; de Conciliis, E; Ferrero, G; Ferro, S; Giaretto, L; Lanfranco, C; Manfredi, R; Miglietta, L; Milanese, S; Parello, G; Simoni, C; Testore, F1
Beijnen, JH; Goey, AK; Huitema, AD; Schellens, JH1
Ahn, HS; Choi, HS; Choi, JY; Kang, HJ; Noh, CI; Park, ES; Shin, HY; Yun, YS1
Anderson, P; Chandra, J; Fulbright, JM; Huh, W1
Balis, FM; Ginsberg, JP; Sepe, DM1
Cunningham, D; Hawkes, EA; Okines, AF; Plummer, C1
Al-Khadimi, Z; Chow, WA; Doroshow, JH; Frankel, P; Lawrence, J; Leong, L; Lim, D; Longmate, J; Margolin, K; Morgan, RJ; Raschko, J; Shibata, S; Somlo, G; Synold, TW; Tetef, ML; Twardowski, P; Yen, Y1
de Vries, EG; Perik, PJ; van den Berg, MP; van Veldhuisen, DJ1
Adamcová, M; Gersl, V; Hrdina, R; Kaplanová, J; Klimtová, I; Mazurová, Y; Simůnek, T; Sterba, M1
Pouillart, P1
Elbl, L; Hrstkova, H; Michalek, J; Tomaskova, I1
Bernitsas, E; Mikol, DD; Wei, W1
De Giorgi, U; Emiliani, E; Frassineti, L; Giannini, M; Giovannini, N; Kopf, B; Marangolo, M; Palazzi, S; Rosti, G; Zumaglini, F1
Lipshultz, SE1
Bosnjak, S; Jelić, S; Kreacić, M; Milanović, N; Nesković-Konstantinović, Z; Radulović, S; Ristović, Z; Vuletić, L1
Garin, AM; Lichinitser, MP; Min'kov, ED; Nakhalova, TA; Odzharova, AA; Vyshinskaia, GV1
Bianchine, JR; Desai, A; Ewer, MS; Gams, RA; Gerber, MC; Jones, SE; Mittelman, A; Pendergrass, K; Reddy, S; Speyer, J; Spicer, D; Swain, SM; Velez-Garcia, E; Vogel, C; Wadler, S; Weisberg, S; Whaley, FS; York, M1
Bianchine, JR; Ewer, MS; Gams, RA; Gerber, MC; Swain, SM; Whaley, FS1
Swain, SM1
Bramwell, V; Moran, LA; Seymour, L1
Bengala, C; Carnino, F; Conte, P; Del Mastro, L; Gallo, L; Lionetto, R; Michelotti, A; Montanaro, E; Rosso, R; Tibaldi, C; Venturini, M1
Carlson, RW1
Creighton, AM; Hopewell, JW; Jaenke, RS; Wilding, D; Yeung, TK1
Ferrans, V; Green, MD; Hochster, H; Kramer, E; Meyers, M; Rey, M; Sanger, J; Speyer, JL; Wernz, JC; Zeleniuch-Jacquotte, A1
Dubin, N; Ferrans, V; Green, MD; Kramer, E; Rey, M; Sanger, J; Speyer, JL; Stecy, P; Ward, C; Zeleniuch-Jacquotte, A1

Reviews

4 review(s) available for razoxane and Heart Failure

ArticleYear
[Dexrazoxane in anthracycline induced cardiotoxicity and extravasation].
    Nederlands tijdschrift voor geneeskunde, 2010, Volume: 154

    Topics: Anthracyclines; Cardiovascular Agents; Heart Diseases; Heart Failure; Humans; Randomized Controlled Trials as Topic; Razoxane

2010
Can anthracycline therapy for pediatric malignancies be less cardiotoxic?
    Current oncology reports, 2010, Volume: 12, Issue:6

    Topics: Adolescent; Adult; Anthracyclines; Child; Delayed-Action Preparations; Disease Progression; Doxorubicin; Drug Administration Schedule; Drug Carriers; Drug Dosage Calculations; Drug-Related Side Effects and Adverse Reactions; Heart; Heart Diseases; Heart Failure; Humans; Iron Chelating Agents; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Randomized Controlled Trials as Topic; Razoxane; Risk Factors; Treatment Outcome

2010
Evaluating the role of dexrazoxane as a cardioprotectant in cancer patients receiving anthracyclines.
    Cancer treatment reviews, 2004, Volume: 30, Issue:7

    Topics: Adult; Animals; Anthracyclines; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cardiomyopathies; Cardiotonic Agents; Child; Heart Failure; Humans; Razoxane

2004
Exposure to anthracyclines during childhood causes cardiac injury.
    Seminars in oncology, 2006, Volume: 33, Issue:3 Suppl 8

    Topics: Adolescent; Adult; Anthracyclines; Antineoplastic Agents; Cardiomyopathies; Cardiovascular Agents; Child; Disease Progression; Heart; Heart Failure; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Razoxane; Risk Factors; Survivors

2006

Trials

10 trial(s) available for razoxane and Heart Failure

ArticleYear
Dexrazoxane for preventing anthracycline cardiotoxicity in children with solid tumors.
    Journal of Korean medical science, 2010, Volume: 25, Issue:9

    Topics: Adolescent; Antibiotics, Antineoplastic; Cardiomyopathies; Cardiovascular Agents; Child; Child, Preschool; Cohort Studies; Disease-Free Survival; Doxorubicin; Echocardiography; Female; Follow-Up Studies; Heart Failure; Humans; Infant; Male; Neoplasms; Razoxane; Ventricular Function, Left

2010
Feasibility and pharmacokinetic study of infusional dexrazoxane and dose-intensive doxorubicin administered concurrently over 96 h for the treatment of advanced malignancies.
    Cancer chemotherapy and pharmacology, 2004, Volume: 54, Issue:3

    Topics: Adult; Antibiotics, Antineoplastic; Cardiovascular Agents; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Granulocyte Colony-Stimulating Factor; Heart Failure; Humans; Infusions, Intravenous; Levofloxacin; Male; Middle Aged; Neoplasms; Neutropenia; Ofloxacin; Razoxane; Sarcoma; Sepsis; Treatment Outcome

2004
Late anthracycline cardiotoxicity protection by dexrazoxane (ICRF-187) in pediatric patients: echocardiographic follow-up.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2006, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Anthracyclines; Antibiotics, Antineoplastic; Cardiomyopathies; Cardiovascular Agents; Child; Child, Preschool; Echocardiography; Female; Follow-Up Studies; Heart Failure; Hematologic Neoplasms; Humans; Male; Razoxane; Retrospective Studies; Stroke Volume; Survival Analysis; Treatment Outcome

2006
Suppression of mitoxantrone cardiotoxicity in multiple sclerosis patients by dexrazoxane.
    Annals of neurology, 2006, Volume: 59, Issue:1

    Topics: Adult; Animals; Antineoplastic Agents; Cardiovascular Agents; Female; Heart Failure; Humans; Male; Middle Aged; Mitoxantrone; Multiple Sclerosis; Razoxane; Stroke Volume; Troponin I

2006
Feasibility of radiotherapy after high-dose dense chemotherapy with epirubicin, preceded by dexrazoxane, and paclitaxel for patients with high-risk Stage II-III breast cancer.
    International journal of radiation oncology, biology, physics, 2006, Jul-15, Volume: 65, Issue:4

    Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Epirubicin; Feasibility Studies; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Heart Failure; Humans; Mastectomy, Segmental; Middle Aged; Neoplasm Staging; Paclitaxel; Prospective Studies; Radiation Pneumonitis; Radiodermatitis; Razoxane; Recombinant Proteins

2006
Cardioprotection with dexrazoxane for doxorubicin-containing therapy in advanced breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:4

    Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cardiovascular Agents; Cyclophosphamide; Disease-Free Survival; Double-Blind Method; Doxorubicin; Female; Fluorouracil; Heart Failure; Humans; Prospective Studies; Razoxane; Risk Factors; Survival Analysis; Treatment Outcome

1997
Delayed administration of dexrazoxane provides cardioprotection for patients with advanced breast cancer treated with doxorubicin-containing therapy.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997, Volume: 15, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cardiovascular Agents; Cyclophosphamide; Disease-Free Survival; Double-Blind Method; Doxorubicin; Drug Administration Schedule; Female; Fluorouracil; Heart Failure; Humans; Middle Aged; Prospective Studies; Razoxane; Treatment Outcome

1997
Single agent epirubicin as first line chemotherapy for metastatic breast cancer patients.
    Breast cancer research and treatment, 2000, Volume: 59, Issue:2

    Topics: Adult; Aged; Antibiotics, Antineoplastic; Breast Neoplasms; Cardiovascular Agents; Epirubicin; Female; Heart Failure; Humans; Injections, Intravenous; Middle Aged; Razoxane; Treatment Outcome; Ventricular Dysfunction, Left

2000
ICRF-187 permits longer treatment with doxorubicin in women with breast cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1992, Volume: 10, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Doxorubicin; Female; Heart Failure; Humans; Life Tables; Middle Aged; Razoxane; Regression Analysis; Survival Analysis; Ventricular Function, Left

1992
Protective effect of the bispiperazinedione ICRF-187 against doxorubicin-induced cardiac toxicity in women with advanced breast cancer.
    The New England journal of medicine, 1988, Sep-22, Volume: 319, Issue:12

    Topics: Adult; Aged; Breast Neoplasms; Cyclophosphamide; Doxorubicin; Drug Tolerance; Female; Fluorouracil; Heart; Heart Failure; Humans; Middle Aged; Myocardium; Piperazines; Radionuclide Imaging; Random Allocation; Razoxane; Stroke Volume

1988

Other Studies

14 other study(ies) available for razoxane and Heart Failure

ArticleYear
Cardiotoxicity debated for anthracyclines and trastuzumab in breast cancer.
    Journal of the National Cancer Institute, 2013, Jun-19, Volume: 105, Issue:12

    Topics: Anthracyclines; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Breast Neoplasms; Cardiotonic Agents; Chelating Agents; Female; Heart; Heart Failure; Humans; Molecular Targeted Therapy; Razoxane; Receptor, ErbB-2; Stroke Volume; Trastuzumab

2013
Cardioprotective effect of dexrazoxane in patients with breast cancer treated with anthracyclines in adjuvant setting: a 10-year single institution experience.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2008, Volume: 8, Issue:4

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cardiovascular Agents; Dose-Response Relationship, Drug; Doxorubicin; Electrocardiography; Epirubicin; Female; Follow-Up Studies; Heart Failure; Humans; Incidence; Life Expectancy; Middle Aged; Neoplasm Metastasis; Razoxane; Retrospective Studies

2008
Dexrazoxane: a second look. Prevention of anthracycline cardiotoxicity: useful for some patients.
    Prescrire international, 2008, Volume: 17, Issue:97

    Topics: Anthracyclines; Chemotherapy, Adjuvant; Drug Approval; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; France; Heart Failure; Humans; Meta-Analysis as Topic; Razoxane

2008
Dexrazoxane as a cardioprotectant in children receiving anthracyclines.
    The oncologist, 2010, Volume: 15, Issue:11

    Topics: Adolescent; Anthracyclines; Antineoplastic Agents; Arrhythmias, Cardiac; Cardiomyopathies; Cardiotonic Agents; Child; Child, Preschool; Heart Failure; Humans; Razoxane; Risk Factors; Treatment Outcome; Young Adult

2010
Cardiotoxicity in patients treated with bevacizumab is potentially reversible.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2011, Jun-20, Volume: 29, Issue:18

    Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Breast Neoplasms; Capecitabine; Clinical Trials as Topic; Clinical Trials, Phase II as Topic; Cyclophosphamide; Deoxycytidine; Dose-Response Relationship, Drug; Doxorubicin; Drug Labeling; Early Termination of Clinical Trials; Epirubicin; Female; Fluorouracil; Heart Failure; Humans; Lymphoma, Large B-Cell, Diffuse; Meta-Analysis as Topic; Paclitaxel; Prednisone; Razoxane; Remission, Spontaneous; Rituximab; Trastuzumab; Vincristine

2011
Experimental animal model for anthracycline-induced heart failure.
    European journal of heart failure, 2004, Volume: 6, Issue:4

    Topics: Animals; Anthracyclines; Body Weight; Cardiovascular Agents; Disease Models, Animal; Heart Failure; Heart Rate; Models, Cardiovascular; Razoxane; Stroke Volume

2004
Rabbit model for in vivo study of anthracycline-induced heart failure and for the evaluation of protective agents.
    European journal of heart failure, 2004, Volume: 6, Issue:4

    Topics: Animals; Anthracyclines; Antibiotics, Antineoplastic; Biomarkers; Body Weight; Cardiovascular Agents; Daunorubicin; Disease Models, Animal; Dose-Response Relationship, Drug; Echocardiography; Erythrocyte Indices; Heart Failure; Heart Rate; Heart Ventricles; Male; Models, Cardiovascular; Myocardium; Myocytes, Cardiac; Rabbits; Razoxane; Stroke Volume; Time Factors

2004
Cardioprotection with ICRF-187 (Cardioxane) in patients with advanced breast cancer having cardiac risk factors for doxorubicin cardiotoxicity, treated with the FDC regimen.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 1995, Volume: 3, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cohort Studies; Cyclophosphamide; Doxorubicin; Echocardiography; Electrocardiography; Female; Fluorouracil; Heart; Heart Failure; Humans; Infusions, Intravenous; Lymphatic Metastasis; Middle Aged; Razoxane; Remission Induction; Risk Factors; Stroke Volume; Ventricular Function, Left

1995
New drug counters doxorubicin cardiotoxicity; not for use at start of chemotherapy.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 1995, Oct-01, Volume: 52, Issue:19

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cardiovascular Agents; Clinical Trials as Topic; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Heart; Heart Failure; Humans; Razoxane

1995
[Cardioxan as a cardioprotector in antineoplastic chemotherapy].
    Klinicheskaia meditsina, 1996, Volume: 74, Issue:5

    Topics: Antibiotics, Antineoplastic; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Cardiovascular Agents; Cyclophosphamide; Doxorubicin; Female; Fluorouracil; Heart; Heart Failure; Humans; Radionuclide Ventriculography; Razoxane; Treatment Outcome

1996
Doxorubicin-induced cardiomyopathy.
    The New England journal of medicine, 1999, Feb-25, Volume: 340, Issue:8

    Topics: Antibiotics, Antineoplastic; Breast Neoplasms; Cardiovascular Agents; Doxorubicin; Heart Failure; Humans; Razoxane

1999
Use of dexrazoxane as a cardioprotectant in patients receiving doxorubicin or epirubicin chemotherapy for the treatment of cancer. The Provincial Systemic Treatment Disease Site Group.
    Cancer prevention & control : CPC = Prevention & controle en cancerologie : PCC, 1999, Volume: 3, Issue:2

    Topics: Aged; Antibiotics, Antineoplastic; Antineoplastic Agents; Breast Neoplasms; Cardiovascular Agents; Clinical Trials as Topic; Doxorubicin; Drug Administration Schedule; Epirubicin; Evidence-Based Medicine; Female; Heart; Heart Failure; Humans; Neoplasms; Odds Ratio; Randomized Controlled Trials as Topic; Razoxane; Time Factors; Treatment Outcome

1999
Reducing the cardiotoxicity of the anthracyclines.
    Oncology (Williston Park, N.Y.), 1992, Volume: 6, Issue:6

    Topics: Antibiotics, Antineoplastic; Biopsy, Needle; Endocardium; Heart Diseases; Heart Failure; Heart Function Tests; Humans; Myocardium; Neoplasms; Razoxane; Risk Factors; Sensitivity and Specificity

1992
The protective activity of ICRF-187 against doxorubicin-induced cardiotoxicity in the rat.
    Cancer chemotherapy and pharmacology, 1992, Volume: 30, Issue:1

    Topics: Animals; Body Weight; Cardiac Output; Dose-Response Relationship, Drug; Doxorubicin; Heart; Heart Diseases; Heart Failure; Heart Rate; Hemorrhage; Male; Pleural Effusion; Rats; Rats, Inbred Strains; Razoxane; Time Factors

1992