Page last updated: 2024-09-03

rasagiline and Neurodegenerative Diseases

rasagiline has been researched along with Neurodegenerative Diseases in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (60.00)29.6817
2010's2 (20.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Bolognesi, ML; Cavalli, A; Melchiorre, C; Minarini, A; Recanatini, M; Rosini, M; Tumiatti, V1
Amoroso, R; Carradori, S; De Filippis, B; Fantacuzzi, M1
Maruyama, W; Naoi, M; Shamoto-Nagai, M1
Alonso, N; Caamaño, O; Cordeiro, MN; García-Mera, X; González-Díaz, H; Luan, F; Romero-Duran, FJ; Yañez, M1
Klivényi, P; Rákóczi, K; Vécsei, L1
Campagna, F; Carotti, A; Catto, M; Leonetti, F; Nicolotti, O; Pisani, L; Stefanachi, A1
Fridkin, M; Youdim, MB; Zheng, H2
Eilam, R; Eliash, S; Shteter, N1
Amit, T; Bar-Am, O; Weinreb, O; Youdim, MB1

Reviews

7 review(s) available for rasagiline and Neurodegenerative Diseases

ArticleYear
Multi-target-directed ligands to combat neurodegenerative diseases.
    Journal of medicinal chemistry, 2008, Feb-14, Volume: 51, Issue:3

    Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Binding Sites; Calcium Channel Blockers; Chelating Agents; Cholinesterase Inhibitors; Humans; Huntington Disease; Ligands; Multiple Sclerosis; Neurodegenerative Diseases; Neurofibrillary Tangles; Neurotransmitter Agents; Parkinson Disease; Plaque, Amyloid

2008
Resveratrol-based compounds and neurodegeneration: Recent insight in multitarget therapy.
    European journal of medicinal chemistry, 2022, Apr-05, Volume: 233

    Topics: Humans; Neurodegenerative Diseases; Polyphenols; Resveratrol; Stilbenes; Structure-Activity Relationship

2022
Neuroprotective Function of Rasagiline and Selegiline, Inhibitors of Type B Monoamine Oxidase, and Role of Monoamine Oxidases in Synucleinopathies.
    International journal of molecular sciences, 2022, Sep-21, Volume: 23, Issue:19

    Topics: alpha-Synuclein; Glial Cell Line-Derived Neurotrophic Factors; Humans; Indans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurodegenerative Diseases; Neuroprotection; Neuroprotective Agents; Proto-Oncogene Proteins c-bcl-2; Selegiline; Synucleinopathies

2022
[Neuroprotection in Parkinson's disease and other neurodegenerative disorders: preclinical and clinical findings].
    Ideggyogyaszati szemle, 2009, Jan-30, Volume: 62, Issue:1-2

    Topics: Animals; Creatine; Dopamine Agonists; Glatiramer Acetate; Humans; Indans; Kynurenic Acid; Micronutrients; Nerve Degeneration; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Peptides; Selegiline; Tocopherols; Ubiquinone

2009
Targeting monoamine oxidases with multipotent ligands: an emerging strategy in the search of new drugs against neurodegenerative diseases.
    Current medicinal chemistry, 2011, Volume: 18, Issue:30

    Topics: Adenosine A2 Receptor Antagonists; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Anti-Inflammatory Agents; Antioxidants; Chelating Agents; Cholinesterase Inhibitors; Drug Design; Drug Discovery; Free Radical Scavengers; Humans; Indans; Ligands; Monoamine Oxidase Inhibitors; Neurodegenerative Diseases; Nitric Oxide Synthase

2011
Bifunctional drug derivatives of MAO-B inhibitor rasagiline and iron chelator VK-28 as a more effective approach to treatment of brain ageing and ageing neurodegenerative diseases.
    Mechanisms of ageing and development, 2005, Volume: 126, Issue:2

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Brain; Chelating Agents; Cholinesterase Inhibitors; Cholinesterases; Culture Media, Serum-Free; Dementia; Dopamine; Dose-Response Relationship, Drug; Humans; Indans; Iron; Lewy Bodies; MAP Kinase Signaling System; Models, Chemical; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurodegenerative Diseases; Neurons; Piperazines; Protein Kinase C; Proto-Oncogene Proteins c-bcl-2; Quinolines

2005
Induction of neurotrophic factors GDNF and BDNF associated with the mechanism of neurorescue action of rasagiline and ladostigil: new insights and implications for therapy.
    Annals of the New York Academy of Sciences, 2007, Volume: 1122

    Topics: Animals; Brain-Derived Neurotrophic Factor; Glial Cell Line-Derived Neurotrophic Factor; Humans; Indans; Neurodegenerative Diseases; Neuroprotective Agents

2007

Other Studies

3 other study(ies) available for rasagiline and Neurodegenerative Diseases

ArticleYear
TOPS-MODE model of multiplexing neuroprotective effects of drugs and experimental-theoretic study of new 1,3-rasagiline derivatives potentially useful in neurodegenerative diseases.
    Bioorganic & medicinal chemistry, 2013, Apr-01, Volume: 21, Issue:7

    Topics: Animals; Computer Simulation; Databases, Pharmaceutical; Drug Discovery; Humans; Indans; Models, Biological; Neurodegenerative Diseases; Neuroprotective Agents; Quantitative Structure-Activity Relationship

2013
Novel bifunctional drugs targeting monoamine oxidase inhibition and iron chelation as an approach to neuroprotection in Parkinson's disease and other neurodegenerative diseases.
    Journal of neural transmission (Vienna, Austria : 1996), 2004, Volume: 111, Issue:10-11

    Topics: Animals; Brain; Drug Delivery Systems; In Vitro Techniques; Indans; Iron Chelating Agents; Male; Mitochondria; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neurodegenerative Diseases; Neuroprotective Agents; Pargyline; Parkinson Disease; Piperazines; Propylamines; Quinolines; Rats; Rats, Sprague-Dawley

2004
Neuroprotective effect of rasagiline, a monoamine oxidase-B inhibitor, on spontaneous cell degeneration in a rat model.
    Journal of neural transmission (Vienna, Austria : 1996), 2005, Volume: 112, Issue:8

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Hypertension; Indans; Male; Monoamine Oxidase Inhibitors; Nerve Degeneration; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Paraventricular Hypothalamic Nucleus; Rats; Rats, Inbred SHR; Rats, Wistar; Third Ventricle; Treatment Outcome; Vasopressins

2005