Page last updated: 2024-09-03

rasagiline and Disease Exacerbation

rasagiline has been researched along with Disease Exacerbation in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (23.08)29.6817
2010's19 (73.08)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Archer, DB; Arpin, DJ; Burciu, RG; Chu, WT; Gao, H; Guttuso, T; Hess, CW; Lai, S; Malaty, IA; McFarland, NR; Mitchell, T; Okun, MS; Pasternak, O; Price, CC; Shukla, AW; Vaillancourt, DE; Wu, SS1
Bhattacharya, SS; Calado, SM; Diaz-Corrales, FJ; Garcia-Delgado, AB; Valdés-Sánchez, L1
Boentert, M; Dorst, J; Dreyhaupt, J; Dupuis, L; Emmer, A; Göricke, B; Grehl, T; Grosskreutz, J; Heneka, MT; Hermann, A; Kassubek, J; Ludolph, AC; Meyer, T; Petri, S; Prudlo, J; Schrank, B; Schuster, J; Weiland, U; Weishaupt, JH; Winkler, AS; Wollebæk Johannesen, S; Zeller, D1
Abler, V; Goebel, G; Krismer, F; Papapetropoulos, S; Poewe, W; Schocke, M; Seppi, K; Wenning, GK1
Chen, Y; Deng, L; Li, J; Qin, X; Sun, H; Tang, R; Yi, L; Zhang, C; Zhang, L; Zhang, Z; Zheng, J; Zhou, H1
Stocchi, F1
Biton, IE; Dror, V; Eliash, S; Rehavi, M1
Bertotti, G; Boveri, N; Comi, C; Frazzitta, G; Ghilardi, MF; Maestri, R; Perini, M; Pezzoli, G; Riboldazzi, G; Turla, M; Uccellini, D1
Müller, T1
Eyal, E; Smith, KM; Weintraub, D1
Hauser, RA; Lang, A; Poewe, W1
Crispin, A; Hensler, M; Lorenzl, S; Nuebling, G; Paul, S; Zwergal, A1
Brotchie, J; Fitzer-Attas, C1
Armand, C; Cochran, J; François, C; Haycox, A; Murteira, S1
Schwarzschild, MA1
Ferreira, JJ; Sampaio, C1
Chen, JJ1
Fitzer-Attas, CJ; Goren, T; Hauser, RA; Hurtig, HI; Lew, MF; Ondo, WG; Wojcieszek, J1
Armand, C; Groenendaal, H; Tarrants, ML1
Bloem, BR; Boon, AJ; van Laar, T1
Barker, RA; Evans, JR1
Rascol, O1
Schapira, AH1
Coria, F; Cozar-Santiago, Mdel P1
Freeman, JW; Matos, E; Simmons, M1

Reviews

6 review(s) available for rasagiline and Disease Exacerbation

ArticleYear
Pharmacokinetic/pharmacodynamic evaluation of rasagiline mesylate for Parkinson's disease.
    Expert opinion on drug metabolism & toxicology, 2014, Volume: 10, Issue:10

    Topics: Animals; Antiparkinson Agents; Catechols; Disease Progression; Humans; Indans; Monoamine Oxidase Inhibitors; Nitriles; Oxidative Stress; Parkinson Disease; Selegiline

2014
Mechanisms compensating for dopamine loss in early Parkinson disease.
    Neurology, 2009, Feb-17, Volume: 72, Issue:7 Suppl

    Topics: Antiparkinson Agents; Corpus Striatum; Disease Progression; Dopamine; Globus Pallidus; Humans; Indans; Levodopa; Neural Pathways; Neurons; Parkinson Disease

2009
Parkinson's disease: health-related quality of life, economic cost, and implications of early treatment.
    The American journal of managed care, 2010, Volume: 16 Suppl Implications

    Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Disease Progression; Early Diagnosis; Health Care Costs; Humans; Indans; Middle Aged; Parkinson Disease; Quality of Life

2010
Defining meaningful outcome measures in trials of disease-modifying therapies in Parkinson's disease.
    Expert opinion on pharmacotherapy, 2011, Volume: 12, Issue:8

    Topics: Disease Progression; Endpoint Determination; Humans; Indans; Movement Disorders; Neuroprotective Agents; Parkinson Disease; Posture; Reflex, Abnormal; Research Design; Treatment Outcome

2011
Present and future drug treatment for Parkinson's disease.
    Journal of neurology, neurosurgery, and psychiatry, 2005, Volume: 76, Issue:11

    Topics: Benzothiazoles; Corpus Striatum; Disease Progression; Dopamine Agonists; Drug Therapy, Combination; Humans; Indans; Indoles; Levodopa; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Parkinson Disease; Pramipexole; Psychomotor Performance; Sexual Dysfunction, Physiological; Sleep Wake Disorders; Substantia Nigra; Thiazoles; Urinary Incontinence

2005
Parkinson disease: an incremental challenge.
    South Dakota medicine : the journal of the South Dakota State Medical Association, 2007, Volume: 60, Issue:12

    Topics: Catechols; Deep Brain Stimulation; Disease Progression; Humans; Indans; Nitriles; Parkinson Disease

2007

Trials

11 trial(s) available for rasagiline and Disease Exacerbation

ArticleYear
Diffusion Magnetic Resonance Imaging Detects Progression in Parkinson's Disease: A Placebo-Controlled Trial of Rasagiline.
    Movement disorders : official journal of the Movement Disorder Society, 2022, Volume: 37, Issue:2

    Topics: Diffusion Magnetic Resonance Imaging; Disease Progression; Double-Blind Method; Humans; Indans; Parkinson Disease; Prospective Studies

2022
Safety and efficacy of rasagiline as an add-on therapy to riluzole in patients with amyotrophic lateral sclerosis: a randomised, double-blind, parallel-group, placebo-controlled, phase 2 trial.
    The Lancet. Neurology, 2018, Volume: 17, Issue:8

    Topics: Aged; Amyotrophic Lateral Sclerosis; Body Mass Index; Disease Progression; Double-Blind Method; Female; Humans; Indans; Male; Middle Aged; Neuroprotective Agents; Retrospective Studies; Riluzole; Treatment Outcome; Vital Capacity

2018
Abnormalities on structural MRI associate with faster disease progression in multiple system atrophy.
    Parkinsonism & related disorders, 2019, Volume: 58

    Topics: Aged; Disease Progression; Double-Blind Method; Female; Follow-Up Studies; Humans; Indans; Magnetic Resonance Imaging; Male; Middle Aged; Multiple System Atrophy; Neuroprotective Agents; Prospective Studies

2019
Efficacy and safety of rasagiline as an adjunct to levodopa treatment in Chinese patients with Parkinson's disease: a randomized, double-blind, parallel-controlled, multi-centre trial.
    The international journal of neuropsychopharmacology, 2013, Volume: 16, Issue:7

    Topics: Adult; Aged; Antiparkinson Agents; Asian People; Cognition Disorders; Disease Progression; Double-Blind Method; Female; Humans; Indans; Levodopa; Male; Middle Aged; Neuroprotective Agents; Parkinson Disease

2013
Benefits of treatment with rasagiline for fatigue symptoms in patients with early Parkinson's disease.
    European journal of neurology, 2014, Volume: 21, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Disease Progression; Double-Blind Method; Fatigue; Female; Humans; Indans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Parkinson Disease; Severity of Illness Index; Treatment Outcome

2014
Intensive rehabilitation treatment in early Parkinson's disease: a randomized pilot study with a 2-year follow-up.
    Neurorehabilitation and neural repair, 2015, Volume: 29, Issue:2

    Topics: Aged; Analysis of Variance; Antiparkinson Agents; Disease Progression; Exercise Therapy; Female; Follow-Up Studies; Humans; Indans; Male; Parkinson Disease; Pilot Projects; Severity of Illness Index; Treatment Outcome; Walking

2015
Combined rasagiline and antidepressant use in Parkinson disease in the ADAGIO study: effects on nonmotor symptoms and tolerability.
    JAMA neurology, 2015, Volume: 72, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Antidepressive Agents; Apathy; Depression; Disease Progression; Double-Blind Method; Drug Therapy, Combination; Fatigue; Female; Humans; Indans; Male; Middle Aged; Neuroprotective Agents; Parkinson Disease; Psychiatric Status Rating Scales; Severity of Illness Index; Sleep; Treatment Outcome; Wakefulness

2015
Effects of rasagiline on the progression of nonmotor scores of the MDS-UPDRS.
    Movement disorders : official journal of the Movement Disorder Society, 2015, Volume: 30, Issue:4

    Topics: Activities of Daily Living; Disease Progression; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Indans; Male; Monoamine Oxidase Inhibitors; Parkinson Disease; Severity of Illness Index; Time Factors; Treatment Outcome

2015
PROSPERA: a randomized, controlled trial evaluating rasagiline in progressive supranuclear palsy.
    Journal of neurology, 2016, Volume: 263, Issue:8

    Topics: Aged; Area Under Curve; Cognition Disorders; Depression; Disease Progression; Double-Blind Method; Electrocardiography; Executive Function; Female; Follow-Up Studies; Humans; Indans; Male; Mental Status Schedule; Middle Aged; Monoamine Oxidase Inhibitors; Postural Balance; Sensation Disorders; Supranuclear Palsy, Progressive

2016
Long-term efficacy of rasagiline in early Parkinson's disease.
    The International journal of neuroscience, 2010, Volume: 120, Issue:6

    Topics: Antiparkinson Agents; Cohort Studies; Disease Progression; Dopamine Agents; Dopamine Agonists; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; Humans; Indans; Kaplan-Meier Estimate; Levodopa; Middle Aged; Parkinson Disease; Severity of Illness Index; Time Factors; Treatment Outcome

2010
A controlled, randomized, delayed-start study of rasagiline in early Parkinson disease.
    Archives of neurology, 2004, Volume: 61, Issue:4

    Topics: Activities of Daily Living; Aged; Antiparkinson Agents; Cohort Studies; Disability Evaluation; Disease Progression; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Indans; Male; Middle Aged; Monoamine Oxidase Inhibitors; Parkinson Disease

2004

Other Studies

9 other study(ies) available for rasagiline and Disease Exacerbation

ArticleYear
Rasagiline delays retinal degeneration in a mouse model of retinitis pigmentosa via modulation of Bax/Bcl-2 expression.
    CNS neuroscience & therapeutics, 2018, Volume: 24, Issue:5

    Topics: Administration, Oral; Animals; Animals, Newborn; bcl-2-Associated X Protein; Disease Models, Animal; Disease Progression; Gene Expression; Indans; Mice, Transgenic; Neuroprotective Agents; Photoreceptor Cells; Proto-Oncogene Proteins c-bcl-2; Retina; Retinitis Pigmentosa; Vision, Ocular

2018
Rasagiline prevents neurodegeneration in thiamine deficient rats-a longitudinal MRI study.
    Brain research, 2014, Apr-04, Volume: 1557

    Topics: Animals; Brain; Diffusion Tensor Imaging; Disease Models, Animal; Disease Progression; Indans; Kaplan-Meier Estimate; Lateral Ventricles; Longitudinal Studies; Magnetic Resonance Imaging; Male; Monoamine Oxidase Inhibitors; Nerve Degeneration; Neuroprotective Agents; Organ Size; Pyrithiamine; Rats; Rats, Sprague-Dawley; Thalamus; Thiamine Deficiency

2014
Cost effectiveness of rasagiline and pramipexole as treatment strategies in early Parkinson's disease in the UK setting: an economic Markov model evaluation.
    Drugs & aging, 2009, Volume: 26, Issue:9

    Topics: Aged; Antiparkinson Agents; Benzothiazoles; Clinical Trials as Topic; Cost-Benefit Analysis; Disease Progression; Dopamine Agonists; Female; Health Care Costs; Humans; Indans; Insurance, Health, Reimbursement; Male; Markov Chains; Middle Aged; Models, Economic; Monoamine Oxidase Inhibitors; Monte Carlo Method; Parkinson Disease; Pramipexole; Probability; Quality-Adjusted Life Years; State Medicine; Treatment Outcome; United Kingdom

2009
Rasagiline in Parkinson's disease.
    The New England journal of medicine, 2010, Feb-18, Volume: 362, Issue:7

    Topics: Disease Progression; Dose-Response Relationship, Drug; Humans; Indans; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Outcome Assessment, Health Care; Parkinson Disease; Research Design

2010
Parkinson disease: ADAGIO trial hints that rasagiline slows disease progression.
    Nature reviews. Neurology, 2010, Volume: 6, Issue:3

    Topics: Clinical Trials as Topic; Disease Progression; Drug Delivery Systems; Humans; Indans; Neuroprotective Agents; Parkinson Disease; Time Factors

2010
Treatment of advanced Parkinson's disease in the United States: a cost-utility model.
    Clinical drug investigation, 2010, Volume: 30, Issue:11

    Topics: Antiparkinson Agents; Carbidopa; Catechols; Cost Savings; Cost-Benefit Analysis; Disease Progression; Drug Administration Schedule; Drug Costs; Drug Therapy, Combination; Humans; Indans; Levodopa; Markov Chains; Models, Economic; Nitriles; Parkinson Disease; Quality of Life; Quality-Adjusted Life Years; Stochastic Processes; Time Factors; Treatment Outcome; United States

2010
[Rasagiline is not for all Parkinson disease patients: the ADAGIO study].
    Nederlands tijdschrift voor geneeskunde, 2010, Volume: 154

    Topics: Disease Progression; Dose-Response Relationship, Drug; Humans; Indans; Monoamine Oxidase Inhibitors; Parkinson Disease; Randomized Controlled Trials as Topic; Treatment Outcome

2010
[Disease-modifying therapies in PD].
    Rinsho shinkeigaku = Clinical neurology, 2010, Volume: 50, Issue:11

    Topics: Animals; Disease Models, Animal; Disease Progression; Dopaminergic Neurons; Endpoint Determination; Humans; Indans; Parkinson Disease; Randomized Controlled Trials as Topic

2010
Rasagiline improves freezing in a patient with primary progressive freezing gait.
    Movement disorders : official journal of the Movement Disorder Society, 2008, Feb-15, Volume: 23, Issue:3

    Topics: Aged, 80 and over; Brain; Disease Progression; Gait Disorders, Neurologic; Humans; Indans; Male; Monoamine Oxidase Inhibitors; Tomography, Emission-Computed, Single-Photon

2008