Page last updated: 2024-08-24

ranolazine and Diastolic Heart Failure

ranolazine has been researched along with Diastolic Heart Failure in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's9 (81.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jacobshagen, C1
Minotti, G1
Belardinelli, L; Edelmann, F; Hasenfuss, G; Jacobshagen, C; Karwatowska-Prokopczuk, E; Lang, C; Layug, B; Lee, S; Maier, LS; Sander, J; Wachter, R1
Gheorghiade, M; Shah, SJ; Vaduganathan, M1
Maier, LS2
Belardinelli, L; Shryock, JC; Song, Y; Wu, Y1
Hoppe, UC; Kochanek, M; Michels, G1
Reddy, BM; Schwartzbard, AZ; Weintraub, HS1
Belardinelli, L; Hasenfuss, G; Jacobshagen, C; Maier, LS1
Belardinelli, L; Dudley, SC; Gu, L; Jeong, EM; Kumar, P; Lardin, HA; Liu, H; Lovelock, JD; Monasky, MM; Patel, BG; Pokhrel, N; Solaro, RJ; Sorescu, D; Taglieri, DM; Zeng, D1

Reviews

6 review(s) available for ranolazine and Diastolic Heart Failure

ArticleYear
[Late sodium current and calcium overload--pathogenesis and adequate treatment].
    Deutsche medizinische Wochenschrift (1946), 2013, Volume: 138, Issue:16

    Topics: Acetanilides; Adrenergic beta-Antagonists; Angina Pectoris; Atrial Fibrillation; Benzazepines; Calcium; Calcium Channel Blockers; Cardiovascular Agents; Coronary Artery Disease; Electrocardiography; Endothelium, Vascular; Heart Failure, Diastolic; Humans; Hypercalcemia; Ivabradine; Myocardial Ischemia; Nitrates; Piperazines; Ranolazine; Sodium; Sodium Channels; Sodium-Calcium Exchanger

2013
Pharmacology at work for cardio-oncology: ranolazine to treat early cardiotoxicity induced by antitumor drugs.
    The Journal of pharmacology and experimental therapeutics, 2013, Volume: 346, Issue:3

    Topics: Acetanilides; Adolescent; Adult; Aged; Antineoplastic Agents; Enzyme Inhibitors; Female; Heart Diseases; Heart Failure, Diastolic; Humans; Male; Middle Aged; Multicenter Studies as Topic; Piperazines; Randomized Controlled Trials as Topic; Ranolazine; Risk Assessment; Young Adult

2013
A novel mechanism for the treatment of angina, arrhythmias, and diastolic dysfunction: inhibition of late I(Na) using ranolazine.
    Journal of cardiovascular pharmacology, 2009, Volume: 54, Issue:4

    Topics: Acetanilides; Angina Pectoris; Animals; Arrhythmias, Cardiac; Clinical Trials as Topic; Heart Failure, Diastolic; Humans; Piperazines; Ranolazine; Sodium; Sodium Channel Blockers; Sodium Channels; Sodium-Calcium Exchanger

2009
[Ranolazine--an additional anti-anginal drug].
    Deutsche medizinische Wochenschrift (1946), 2010, Volume: 135, Issue:41

    Topics: Acetanilides; Angina Pectoris; Atrial Fibrillation; Biological Availability; Blood Pressure; Double-Blind Method; Enzyme Inhibitors; Heart Failure, Diastolic; Heart Rate; Humans; Metabolic Clearance Rate; Piperazines; Randomized Controlled Trials as Topic; Ranolazine

2010
Ranolazine: a new approach to treating an old problem.
    Texas Heart Institute journal, 2010, Volume: 37, Issue:6

    Topics: Acetanilides; Angina Pectoris; Angina, Unstable; Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Evidence-Based Medicine; Heart Diseases; Heart Failure, Diastolic; Humans; Myocardial Infarction; Piperazines; Practice Guidelines as Topic; Ranolazine; Sodium Channel Blockers; Treatment Outcome

2010
New treatment options for late Na current, arrhythmias, and diastolic dysfunction.
    Current heart failure reports, 2012, Volume: 9, Issue:3

    Topics: Acetanilides; Action Potentials; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Calcium; Cardiovascular Agents; Cations; Diastole; Enzyme Inhibitors; Heart Failure; Heart Failure, Diastolic; Humans; Myocardial Contraction; NAV1.5 Voltage-Gated Sodium Channel; Piperazines; Ranolazine; Sodium; Sodium-Calcium Exchanger

2012

Trials

2 trial(s) available for ranolazine and Diastolic Heart Failure

ArticleYear
RAnoLazIne for the treatment of diastolic heart failure in patients with preserved ejection fraction: the RALI-DHF proof-of-concept study.
    JACC. Heart failure, 2013, Volume: 1, Issue:2

    Topics: Acetanilides; Aged; Double-Blind Method; Female; Heart Failure, Diastolic; Humans; Male; Piperazines; Prospective Studies; Ranolazine; Sodium Channel Blockers; Stroke Volume

2013
Ranolazine for the treatment of heart failure with preserved ejection fraction: background, aims, and design of the RALI-DHF study.
    Clinical cardiology, 2011, Volume: 34, Issue:7

    Topics: Acetanilides; Administration, Oral; Biomarkers; Cardiac Catheterization; Cardiovascular Agents; Double-Blind Method; Echocardiography, Doppler; Germany; Heart Failure, Diastolic; Humans; Infusions, Intravenous; Natriuretic Peptide, Brain; Oxygen Consumption; Peptide Fragments; Piperazines; Placebo Effect; Prospective Studies; Ranolazine; Recovery of Function; Research Design; Stroke Volume; Time Factors; Treatment Outcome; Ventricular Function, Left; Ventricular Pressure

2011

Other Studies

3 other study(ies) available for ranolazine and Diastolic Heart Failure

ArticleYear
Evaluative framework for phase II studies in patients with heart failure and preserved ejection fraction.
    JACC. Heart failure, 2013, Volume: 1, Issue:2

    Topics: Acetanilides; Female; Heart Failure, Diastolic; Humans; Male; Piperazines; Ranolazine; Sodium Channel Blockers

2013
The late Na+ current (INa) inhibitor ranolazine attenuates effects of palmitoyl-L-carnitine to increase late INa and cause ventricular diastolic dysfunction.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 330, Issue:2

    Topics: Acetanilides; Animals; Female; Guinea Pigs; Heart Failure, Diastolic; In Vitro Techniques; Male; Myocytes, Cardiac; Palmitoylcarnitine; Piperazines; Ranolazine; Sodium Channel Blockers; Sodium Channels; Ventricular Dysfunction

2009
Ranolazine improves cardiac diastolic dysfunction through modulation of myofilament calcium sensitivity.
    Circulation research, 2012, Mar-16, Volume: 110, Issue:6

    Topics: Acetanilides; Animals; Calcium; Desoxycorticosterone; Diastole; Disease Models, Animal; Enzyme Inhibitors; Heart Failure, Diastolic; Mice; Mineralocorticoids; Myocardial Contraction; Myocytes, Cardiac; Myofibrils; Oxidative Stress; Piperazines; Ranolazine; Sodium; Ventricular Dysfunction, Left

2012