Page last updated: 2024-08-24

ranolazine and Arrhythmia

ranolazine has been researched along with Arrhythmia in 53 studies

Research

Studies (53)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	9 (16.98)	29.6817
2010's	38 (71.70)	24.3611
2020's	6 (11.32)	2.80

Authors

Authors	Studies
Andrade, JG; Deyell, MW	1
Costa, AD; Cruz, JS; Durço, AO; Joviano-Santos, JV; Marques, LP; Rhana, P; Roman-Campos, D; Santos-Miranda, A; Souza, DS; Vasconcelos, CML	1
Chan, CS; Chen, SA; Chen, YC; Chen, YJ; Higa, S; Lin, FJ; Lin, YK; Liu, CM; Lu, YY	1
Shen, C; Stabenau, HF; Tereshchenko, LG; Waks, JW	1
Beserra, SS; Campos, DR; Miranda, VM	1
Abacioglu, N; Chukwunyere, U; Sehirli, AO	1
Ahmad, S; Bengel, P; Sossalla, S	1
Karthikeyan, VJ; Mezincescu, A; Nadar, SK	1
Fukaya, H; Laurita, KR; Piktel, JS; Plummer, BN; Rosenbaum, DS; Wan, X; Wilson, LD	1
Rubart, M	1
Bögeholz, N; Eckardt, L; Ellermann, C; Frommeyer, G; Lange, PS; Leitz, P; Puckhaber, D; Wolfes, J	1
Belardinelli, L; Danner, BC; Fischer, TH; Hartmann, N; Hasenfuss, G; Herting, J; Hund, TJ; Maier, LS; Mohler, PJ; Sag, CM; Sossalla, S; Toischer, K; Wagner, S	1
Bacchini, S; Barbieri, L; Bongo, AS; Cavallino, C; Degiovanni, A; Lazzero, M; Lupi, A; Nardi, F; Rametta, F; Rognoni, A; Veia, A	1
Geunes-Boyer, S; Hines, ME; Kloner, RA	1
Clauss, C; Eckardt, L; Frommeyer, G; Grotthoff, JS; Grundmann, F; Kaese, S; Milberg, P; Pott, C; Ramtin, S; Schmidt, M	1
Belardinelli, L; Kanas, AF; Morrow, DA; Nearing, BD; Nieminen, T; Pagotto, VP; Pegler, JR; Scirica, BM; Sobrado, MF; Tavares, C; Umez-Eronini, AA; Verrier, RL	1
Chao, TF; Chen, SA; Chen, YC; Chen, YJ; Chung, FP; Huang, JH; Kao, YH; Lu, YY; Tsai, CF	1
Acharjee, S; Codolosa, JN; Figueredo, VM	1
Belardinelli, L; Bhimani, AA; Khrestian, CM; Lee, S; Sadrpour, SA; Waldo, AL; Yasuda, T; Zeng, D	1
Hale, SL; Kloner, RA	1
Belardinelli, L; Chi, L; Dhalla, AK; Hoyer, K; Liles, JT; Oliver, J	1
Glynn, P; Gyorke, S; Hund, TJ; Little, S; Mohler, PJ; Musa, H; Qian, L; Radwanski, PB; Unudurthi, SD; Wright, PJ; Wu, X	1
Manolis, AS; Polytarchou, K	1
Elgendy, IY; Mahmoud, A; Richard Conti, C; Saad, M	1
Guo, J; Im, K; Morrow, DA; Patel, RB; Scirica, BM; Tannenbaum, S; Viana-Tejedor, A	1
Mao, W; Wei, X; Yao, S; Zhang, Y; Zhu, A	1
Assadi, H; Heidary, S; Shenasa, H; Shenasa, M	1
Bögeholz, N; Dechering, DG; Eckardt, L; Ellermann, C; Frommeyer, G; Güner, F; Kochhäuser, S; Leitz, P; Pott, C	1
Kluger, J; Pulford, BR	1
Eckardt, L; Ellermann, C; Frommeyer, G	1
Hancox, JC	1
Balijepalli, RC; Belardinelli, L; Hacker, TA; Markandeya, YS; Tsubouchi, T; Wolff, MR	1
Stone, PH	1
Maier, LS	2
DiMarco, JP; Mason, PK	1
Foster, NJ; Haines, DE	1
Antzelevitch, C; Belardinelli, L; Burashnikov, A; Sicouri, S	1
Chartier, D; Comtois, P; Duverger, JE; Fabritz, L; Kirchhof, P; Lemoine, MD; Nattel, S; Naud, P; Qi, XY	1
Adler, A; Viskin, S	1
Caballero, R; Delpón, E; Tamargo, J	1
Zaza, A	1
Cingolani, E; Lepor, NE; Singh, BN	1
Bonadei, I; Bontempi, L; Curnis, A; D'Aloia, A; Dei Cas, L; Quinzani, F; Rovetta, R; Vizzardi, E	1
Bernus, O; Boycott, HE; Boyle, JP; Dallas, ML; Duke, A; Elies, J; Milligan, CJ; Peers, C; Reboul, C; Richard, S; Scragg, JL; Steele, DS; Thireau, J; Yang, Z	1
Andrikopoulos, G; Tzeis, S	1
Belardinelli, L; Crumb, W; Dhalla, AK; El-Bizri, N; Hirakawa, R; Hu, L; Karpinski, S; Koltun, D; Li, CH; Li, XJ; Liu, G; Rajamani, S; Shryock, JC; Smith-Maxwell, C; Wang, WQ; Wu, L; Yao, L; Zablocki, J	1
Kong, L; Luo, A; Ma, J; Qian, C; Ren, Z; Wang, C; Wang, X; Wu, Y; Zhang, P; Zhang, S	1
Makielski, JC; Valdivia, CR	1
Belardinelli, L; Fraser, H; Shryock, JC	1
Belardinelli, L; Braunwald, E; Gersh, BJ; Hedgepeth, CM; Hod, H; McCabe, CH; Molhoek, P; Morrow, DA; Murphy, SA; Scirica, BM; Verheugt, FW	1
Clark, AL; Cleland, JG; Coletta, AP; Louis, AA; Manousos, IR	1

Reviews

21 review(s) available for ranolazine and Arrhythmia

Article	Year
Inhibition of Late Sodium Current as an Innovative Antiarrhythmic Strategy. Current heart failure reports, 2017, Volume: 14, Issue:3 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Heart Failure; Humans; Long QT Syndrome; Ranolazine; Sodium Channel Blockers; Sodium Channels	2017
Ranolazine: A true pluripotent cardiovascular drug or jack of all trades, master of none? Sultan Qaboos University medical journal, 2018, Volume: 18, Issue:1 Topics: Arrhythmias, Cardiac; Cardiovascular Diseases; Heart Failure; Humans; Ranolazine; Sodium Channel Blockers	2018
Ranolazine: effects on ischemic heart. Recent patents on cardiovascular drug discovery, 2013, Volume: 8, Issue:3 Topics: Acetanilides; Angina, Stable; Animals; Arrhythmias, Cardiac; Clinical Trials as Topic; Diabetes Mellitus; Drug Interactions; Heart Failure; Humans; Myocardial Ischemia; Piperazines; Ranolazine; Sodium Channel Blockers	2013
Efficacy and safety of ranolazine in patients with chronic stable angina. Postgraduate medicine, 2013, Volume: 125, Issue:6 Topics: Acetanilides; Angina, Stable; Arrhythmias, Cardiac; Diabetes Mellitus, Type 2; Drug Interactions; Electrocardiography; Enzyme Inhibitors; Geriatrics; Glycated Hemoglobin; Humans; Piperazines; Randomized Controlled Trials as Topic; Ranolazine	2013
Update on ranolazine in the management of angina. Vascular health and risk management, 2014, Volume: 10 Topics: Acetanilides; Angina Pectoris; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chronic Disease; Cost Savings; Cost-Benefit Analysis; Drug Costs; Hospital Costs; Hospitalization; Humans; Piperazines; Ranolazine; Sodium Channel Blockers; Treatment Outcome	2014
Ranolazine treatment for myocardial infarction? Effects on the development of necrosis, left ventricular function and arrhythmias in experimental models. Cardiovascular drugs and therapy, 2014, Volume: 28, Issue:5 Topics: Acetanilides; Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Disease Models, Animal; Myocardial Infarction; Necrosis; Piperazines; Ranolazine; Reperfusion Injury; Ventricular Function, Left	2014
Ranolazine and its Antiarrhythmic Actions. Cardiovascular & hematological agents in medicinal chemistry, 2015, Volume: 13, Issue:1 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Clinical Trials as Topic; Humans; Ranolazine	2015
Ranolazine in Cardiac Arrhythmia. Clinical cardiology, 2016, Volume: 39, Issue:3 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Heart Conduction System; Heart Rate; Humans; Kinetics; Ranolazine; Sodium Channel Blockers; Sodium Channels; Treatment Outcome	2016
Ranolazine: Electrophysiologic Effect, Efficacy, and Safety in Patients with Cardiac Arrhythmias. Cardiac electrophysiology clinics, 2016, Volume: 8, Issue:2 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Humans; Ranolazine	2016
Ranolazine Therapy in Cardiac Arrhythmias. Pacing and clinical electrophysiology : PACE, 2016, Volume: 39, Issue:9 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Drug Administration Schedule; Evidence-Based Medicine; Humans; Ranolazine; Treatment Outcome	2016
Ranolazine: new paradigm for management of myocardial ischemia, myocardial dysfunction, and arrhythmias. Cardiology clinics, 2008, Volume: 26, Issue:4 Topics: Acetanilides; Angina Pectoris; Animals; Arrhythmias, Cardiac; Cardiomyopathies; Drug Therapy, Combination; Heart Failure; Humans; Myocardial Ischemia; Piperazines; Ranolazine	2008
A novel mechanism for the treatment of angina, arrhythmias, and diastolic dysfunction: inhibition of late I(Na) using ranolazine. Journal of cardiovascular pharmacology, 2009, Volume: 54, Issue:4 Topics: Acetanilides; Angina Pectoris; Animals; Arrhythmias, Cardiac; Clinical Trials as Topic; Heart Failure, Diastolic; Humans; Piperazines; Ranolazine; Sodium; Sodium Channel Blockers; Sodium Channels; Sodium-Calcium Exchanger	2009
New pharmacological agents for arrhythmias. Circulation. Arrhythmia and electrophysiology, 2009, Volume: 2, Issue:5 Topics: Acetanilides; Adenosine A1 Receptor Agonists; Amiodarone; Anisoles; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzazepines; Benzofurans; Clinical Trials as Topic; Dronedarone; Humans; Ivabradine; Piperazines; Pyrrolidines; Ranolazine	2009
The antiarrhythmic effects of ranolazine. Reviews in cardiovascular medicine, 2009, Volume: 10 Suppl 1 Topics: Acetanilides; Acute Coronary Syndrome; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Heart Conduction System; Humans; Long QT Syndrome; Piperazines; Potassium Channel Blockers; Ranolazine; Sick Sinus Syndrome; Sodium Channel Blockers; Treatment Outcome	2009
Electrophysiologic basis for the antiarrhythmic actions of ranolazine. Heart rhythm, 2011, Volume: 8, Issue:8 Topics: Acetanilides; Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channels; Electrophysiologic Techniques, Cardiac; Heart; Heart Atria; Heart Ventricles; Humans; Ion Channels; Membrane Potentials; Myocytes, Cardiac; Piperazines; Potassium Channels; Ranolazine; Species Specificity	2011
Ranolazine: an antianginal drug with antiarrhythmic properties. Expert review of cardiovascular therapy, 2011, Volume: 9, Issue:7 Topics: Acetanilides; Angina Pectoris; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Humans; Piperazines; Ranolazine; Sodium Channel Blockers	2011
[The late sodium current: pathophysiology and pharmacology of a new therapeutic target]. Giornale italiano di cardiologia (2006), 2011, Volume: 12, Issue:10 Suppl 2 Topics: Acetanilides; Arrhythmias, Cardiac; Disease Progression; Enzyme Inhibitors; Heart Conduction System; Heart Diseases; Humans; Muscle Cells; Myocardial Contraction; Myocardial Ischemia; Piperazines; Ranolazine; Sodium; Sodium Channels; Treatment Outcome	2011
The electrophysiological properties of ranolazine: a metabolic anti-ischemic drug or an energy-efficient antiarrhythmic agent? Reviews in cardiovascular medicine, 2011, Volume: 12, Issue:3 Topics: Acetanilides; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Energy Metabolism; Heart Conduction System; Humans; Myocardial Ischemia; Myocardium; Piperazines; Ranolazine	2011
A focus on antiarrhythmic properties of ranolazine. Journal of cardiovascular pharmacology and therapeutics, 2012, Volume: 17, Issue:4 Topics: Acetanilides; Action Potentials; Angina Pectoris; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Heart Atria; Heart Ventricles; Humans; Ion Channels; Membrane Transport Modulators; Piperazines; Ranolazine	2012
New treatment options for late Na current, arrhythmias, and diastolic dysfunction. Current heart failure reports, 2012, Volume: 9, Issue:3 Topics: Acetanilides; Action Potentials; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Calcium; Cardiovascular Agents; Cations; Diastole; Enzyme Inhibitors; Heart Failure; Heart Failure, Diastolic; Humans; Myocardial Contraction; NAV1.5 Voltage-Gated Sodium Channel; Piperazines; Ranolazine; Sodium; Sodium-Calcium Exchanger	2012
Clinical trials update: The Heart Protection Study, IONA, CARISA, ENRICHD, ACUTE, ALIVE, MADIT II and REMATCH. Impact Of Nicorandil on Angina. Combination Assessment of Ranolazine In Stable Angina. ENhancing Recovery In Coronary Heart Disease patients. As European journal of heart failure, 2002, Volume: 4, Issue:1 Topics: Acetanilides; Angina Pectoris; Arrhythmias, Cardiac; Cardiology; Clinical Trials as Topic; Comorbidity; Coronary Disease; Defibrillators, Implantable; Depressive Disorder; Electric Countershock; Female; Heart Failure; Humans; Male; Nicorandil; Piperazines; Ranolazine; Sensitivity and Specificity	2002

Trials

3 trial(s) available for ranolazine and Arrhythmia

Article	Year
Relation of T-wave alternans to mortality and nonsustained ventricular tachycardia in patients with non-ST-segment elevation acute coronary syndrome from the MERLIN-TIMI 36 trial of ranolazine versus placebo. The American journal of cardiology, 2014, Jul-01, Volume: 114, Issue:1 Topics: Acetanilides; Acute Coronary Syndrome; Aged; Arrhythmias, Cardiac; Brugada Syndrome; Cardiac Conduction System Disease; Death, Sudden, Cardiac; Electrocardiography; Enzyme Inhibitors; Female; Heart Conduction System; Humans; Male; Middle Aged; Piperazines; Placebos; Predictive Value of Tests; Ranolazine; Risk Factors; Tachycardia, Ventricular; Treatment Outcome	2014
Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. European heart journal. Acute cardiovascular care, 2017, Volume: 6, Issue:1 Topics: Aged; Angina, Unstable; Arrhythmias, Cardiac; Cardiovascular Agents; Electrocardiography; Female; Humans; Male; Middle Aged; Non-ST Elevated Myocardial Infarction; Potassium; Ranolazine	2017
Effect of ranolazine, an antianginal agent with novel electrophysiological properties, on the incidence of arrhythmias in patients with non ST-segment elevation acute coronary syndrome: results from the Metabolic Efficiency With Ranolazine for Less Ischem Circulation, 2007, Oct-09, Volume: 116, Issue:15 Topics: Acetanilides; Acute Disease; Aged; Angina Pectoris; Arrhythmias, Cardiac; Coronary Disease; Diabetic Angiopathies; Electrocardiography; Electrophysiology; Female; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Piperazines; Placebos; Ranolazine; Tachycardia; Thrombolytic Therapy	2007

Other Studies

29 other study(ies) available for ranolazine and Arrhythmia

Article	Year
A Role for Ranolazine in the Treatment of Ventricular Arrhythmias? JACC. Clinical electrophysiology, 2022, Volume: 8, Issue:6 Topics: Arrhythmias, Cardiac; Humans; Ranolazine; Tachycardia, Ventricular	2022
Experimental hypothyroidism induces cardiac arrhythmias and ranolazine reverts and prevents the phenotype. Life sciences, 2022, Nov-01, Volume: 308 Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Caffeine; Dobutamine; Hypothyroidism; Male; Methimazole; Mice; Myocytes, Cardiac; Phenotype; Ranolazine; Sodium	2022
Modulation of post-pacing action potential duration and contractile responses on ventricular arrhythmogenesis in chloroquine-induced long QT syndrome. European journal of pharmacology, 2023, Feb-15, Volume: 941 Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Azithromycin; Long QT Syndrome; Rabbits; Ranolazine; Sodium; Tachycardia, Ventricular	2023
Changes in global electrical heterogeneity associated with dofetilide, quinidine, ranolazine, and verapamil. Heart rhythm, 2020, Volume: 17, Issue:3 Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Female; Heart Ventricles; Humans; Male; Phenethylamines; Potassium Channel Blockers; Quinidine; Ranolazine; Risk Assessment; Sodium Channel Blockers; Sulfonamides; Treatment Outcome	2020
Inotropic and Antiarrhythmic Transmural Actions of Ranolazine in a Cellular Model of Type 3 Long QT Syndrome. Arquivos brasileiros de cardiologia, 2020, Volume: 114, Issue:4 Topics: Action Potentials; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Conduction System Disease; Humans; Long QT Syndrome; Ranolazine	2020
COVID-19-related arrhythmias and the possible effects of ranolazine. Medical hypotheses, 2021, Volume: 149 Topics: Action Potentials; Angina, Stable; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; COVID-19; COVID-19 Drug Treatment; Cytokines; Hemodynamics; Humans; Inflammation; Potassium Channels; Ranolazine; Sodium Channel Blockers	2021
Arrhythmogenic cardiac alternans in heart failure is suppressed by late sodium current blockade by ranolazine. Heart rhythm, 2019, Volume: 16, Issue:2 Topics: Animals; Arrhythmias, Cardiac; Calcium; Disease Models, Animal; Dogs; Heart Conduction System; Heart Failure; Myocytes, Cardiac; Optical Imaging; Ranolazine; Sodium Channel Blockers	2019
The coronary sinus: Novel arrhythmogenic aspects. Journal of cardiovascular electrophysiology, 2019, Volume: 30, Issue:2 Topics: Animals; Arrhythmias, Cardiac; Autonomic Nervous System; Coronary Sinus; Dogs; Heart; Ranolazine	2019
Digitalis Promotes Ventricular Arrhythmias in Flecainide- and Ranolazine-Pretreated Hearts. Cardiovascular toxicology, 2019, Volume: 19, Issue:3 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiotoxicity; Digitalis Glycosides; Drug Interactions; Flecainide; Heart Rate; Isolated Heart Preparation; Ouabain; Rabbits; Ranolazine; Refractory Period, Electrophysiological; Risk Assessment; Time Factors; Voltage-Gated Sodium Channel Blockers	2019
Role of late sodium current as a potential arrhythmogenic mechanism in the progression of pressure-induced heart disease. Journal of molecular and cellular cardiology, 2013, Volume: 61 Topics: Acetanilides; Action Potentials; Animals; Arrhythmias, Cardiac; Blood Pressure; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiomegaly; Cells, Cultured; Female; Heart Failure; Heart Ventricles; Mice; Mice, Inbred C57BL; NAV1.1 Voltage-Gated Sodium Channel; Patch-Clamp Techniques; Peptides; Piperazines; Ranolazine; Sodium; Sodium Channel Blockers; Tetrodotoxin	2013
Electrophysiological profile of vernakalant in an experimental whole-heart model: the absence of proarrhythmia despite significant effect on myocardial repolarization. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2014, Volume: 16, Issue:8 Topics: Acetanilides; Action Potentials; Animals; Anisoles; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrophysiologic Techniques, Cardiac; Heart Conduction System; In Vitro Techniques; Models, Animal; Perfusion; Piperazines; Potassium Channel Blockers; Pyrrolidines; Rabbits; Ranolazine; Risk Assessment; Risk Factors; Sodium Channel Blockers; Sotalol; Time Factors	2014
Distinctive electrophysiological characteristics of right ventricular out-flow tract cardiomyocytes. Journal of cellular and molecular medicine, 2014, Volume: 18, Issue:8 Topics: Acetanilides; Action Potentials; Animals; Arrhythmias, Cardiac; Benzylamines; Brugada Syndrome; Calcium; Cardiac Conduction System Disease; Electrophysiological Phenomena; Enzyme Inhibitors; Heart Conduction System; Heart Ventricles; Myocytes, Cardiac; Patch-Clamp Techniques; Piperazines; Protein Kinase Inhibitors; Rabbits; Ranolazine; Sodium-Calcium Exchanger; Sulfonamides	2014
Ranolazine terminates atrial flutter and fibrillation in a canine model. Heart rhythm, 2014, Volume: 11, Issue:9 Topics: Acetanilides; Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Brugada Syndrome; Cardiac Conduction System Disease; Disease Models, Animal; Dogs; Electrocardiography; Enzyme Inhibitors; Heart Conduction System; Heart Rate; Injections, Intravenous; Piperazines; Ranolazine; Sodium Channel Blockers; Treatment Outcome	2014
Ranolazine reduces remodeling of the right ventricle and provoked arrhythmias in rats with pulmonary hypertension. The Journal of pharmacology and experimental therapeutics, 2015, Volume: 353, Issue:3 Topics: Acetanilides; Animals; Arrhythmias, Cardiac; Collagen; Electrocardiography; Enzyme Inhibitors; Fibrosis; Hypertension, Pulmonary; In Vitro Techniques; Piperazines; Ranolazine; Rats; Rats, Sprague-Dawley; Ventricular Remodeling	2015
Voltage-Gated Sodium Channel Phosphorylation at Ser571 Regulates Late Current, Arrhythmia, and Cardiac Function In Vivo. Circulation, 2015, Aug-18, Volume: 132, Issue:7 Topics: Acetanilides; Action Potentials; Animals; Arrhythmias, Cardiac; Calcium; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiomegaly; Constriction; Gene Knock-In Techniques; Ion Channel Gating; Male; Mice; Mice, Inbred C57BL; NAV1.5 Voltage-Gated Sodium Channel; Phosphorylation; Phosphoserine; Piperazines; Protein Processing, Post-Translational; Ranolazine; Sodium; Sodium Channel Blockers; Ventricular Remodeling	2015
Pre- and Delayed Treatments With Ranolazine Ameliorate Ventricular Arrhythmias and Nav1.5 Downregulation in Ischemic/Reperfused Rat Hearts. Journal of cardiovascular pharmacology, 2016, Volume: 68, Issue:4 Topics: Animals; Arrhythmias, Cardiac; Down-Regulation; Drug Administration Schedule; Electrocardiography; Male; Myocardial Reperfusion Injury; NAV1.5 Voltage-Gated Sodium Channel; Random Allocation; Ranolazine; Rats; Rats, Sprague-Dawley; Treatment Outcome	2016
Ranolazine and Vernakalant Prevent Ventricular Arrhythmias in an Experimental Whole-Heart Model of Short QT Syndrome. Journal of cardiovascular electrophysiology, 2016, Volume: 27, Issue:10 Topics: Action Potentials; Animals; Anisoles; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiac Pacing, Artificial; Disease Models, Animal; Electrocardiography; Heart Rate; Isolated Heart Preparation; Pinacidil; Pyrrolidines; Rabbits; Ranolazine; Sodium Channel Blockers; Time Factors; Ventricular Fibrillation	2016
Considering Ranolazine as a Potential Treatment for K Journal of cardiovascular electrophysiology, 2016, Volume: 27, Issue:10 Topics: Acetanilides; Arrhythmias, Cardiac; Humans; Ranolazine	2016
Considering Ranolazine as a Potential Treatment for K Journal of cardiovascular electrophysiology, 2016, Volume: 27, Issue:10 Topics: Acetanilides; Arrhythmias, Cardiac; Humans; Ranolazine	2016
Inhibition of late sodium current attenuates ionic arrhythmia mechanism in ventricular myocytes expressing LaminA-N195K mutation. Heart rhythm, 2016, Volume: 13, Issue:11 Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Cardiomyopathy, Dilated; Disease Models, Animal; Heart Ventricles; Lamin Type A; Mice; Mutation, Missense; Myocytes, Cardiac; Ranolazine; Sodium Channel Blockers; Sodium Channels	2016
Ranolazine: new drug. Stable angina: not worth the risk. Prescrire international, 2009, Volume: 18, Issue:102 Topics: Acetanilides; Angina Pectoris; Arrhythmias, Cardiac; Cost-Benefit Analysis; Double-Blind Method; Drug Approval; Drug Interactions; Drug Therapy, Combination; Enzyme Inhibitors; Europe; Humans; Piperazines; Randomized Controlled Trials as Topic; Ranolazine	2009
Arrhythmogenic left atrial cellular electrophysiology in a murine genetic long QT syndrome model. Cardiovascular research, 2011, Oct-01, Volume: 92, Issue:1 Topics: Acetanilides; Action Potentials; Animals; Arrhythmias, Cardiac; Disease Models, Animal; Heart Atria; Long QT Syndrome; Male; Mice; NAV1.5 Voltage-Gated Sodium Channel; Piperazines; Ranolazine; Sodium Channels	2011
Ranolazine: Déjà vu of the amiodarone story. Heart rhythm, 2011, Volume: 8, Issue:8 Topics: Acetanilides; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Heart; Humans; Piperazines; Ranolazine	2011
Carbon monoxide induces cardiac arrhythmia via induction of the late Na+ current. American journal of respiratory and critical care medicine, 2012, Oct-01, Volume: 186, Issue:7 Topics: Acetanilides; Action Potentials; Animals; Arrhythmias, Cardiac; Calcium Signaling; Carbon Monoxide; Carbon Monoxide Poisoning; Cell Culture Techniques; Disease Models, Animal; Environmental Exposure; Enzyme Inhibitors; Male; Myocytes, Cardiac; Patch-Clamp Techniques; Piperazines; Ranolazine; Rats; Rats, Wistar; Voltage-Gated Sodium Channels	2012
Antiarrhythmic properties of ranolazine--from bench to bedside. Expert opinion on investigational drugs, 2012, Volume: 21, Issue:11 Topics: Acetanilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Clinical Trials as Topic; Humans; Piperazines; Ranolazine; Tachycardia, Ventricular	2012
A novel, potent, and selective inhibitor of cardiac late sodium current suppresses experimental arrhythmias. The Journal of pharmacology and experimental therapeutics, 2013, Volume: 344, Issue:1 Topics: Acetanilides; Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiotonic Agents; Cnidarian Venoms; Female; Flecainide; Heart Conduction System; Long QT Syndrome; Mutation; Myocardial Ischemia; Myocytes, Cardiac; Patch-Clamp Techniques; Piperazines; Potassium Channel Blockers; Pyridines; Quaternary Ammonium Compounds; Rabbits; Ranolazine; Sodium Channel Blockers; Triazoles	2013
Resveratrol attenuates the Na(+)-dependent intracellular Ca(2+) overload by inhibiting H(2)O(2)-induced increase in late sodium current in ventricular myocytes. PloS one, 2012, Volume: 7, Issue:12 Topics: Acetanilides; Animals; Antioxidants; Arrhythmias, Cardiac; Calcium; Diastole; Dose-Response Relationship, Drug; Electrophysiology; Female; Heart Ventricles; Hydrogen Peroxide; Ischemia; Male; Muscle Cells; Patch-Clamp Techniques; Piperazines; Rabbits; Ranolazine; Resveratrol; Sodium; Stilbenes; Temperature; Tetrodotoxin	2012
Ranolazine and late cardiac sodium current--a therapeutic target for angina, arrhythmia and more? British journal of pharmacology, 2006, Volume: 148, Issue:1 Topics: Acetanilides; Angina Pectoris; Animals; Arrhythmias, Cardiac; Long QT Syndrome; Mutation; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Piperazines; Ranolazine; Sodium; Sodium Channel Blockers; Sodium Channels	2006
Inhibition of the late sodium current as a potential cardioprotective principle: effects of the late sodium current inhibitor ranolazine. Heart (British Cardiac Society), 2006, Volume: 92 Suppl 4 Topics: Acetanilides; Animals; Arrhythmias, Cardiac; Calcium; Enzyme Inhibitors; Homeostasis; Humans; Myocytes, Cardiac; Piperazines; Ranolazine; Sodium; Sodium Channel Blockers; Sodium Channels; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase	2006