ramelteon has been researched along with Chronic Insomnia in 98 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 55 (56.12) | 29.6817 |
| 2010's | 38 (38.78) | 24.3611 |
| 2020's | 5 (5.10) | 2.80 |
| Authors | Studies |
|---|---|
| Dubocovich, ML; Hudson, RL; Rawashdeh, O; Stepien, I | 1 |
| Cecon, E; Jockers, R; Rivara, S; Witt-Enderby, PA; Zlotos, DP | 1 |
| Bourgin, P; Chambe, J; Geoffroy, PA; Maruani, J; Palagini, L; Reynaud, E | 1 |
| Adams, AD; Brown, JN; Pepin, MJ | 1 |
| Hashioka, S; Inagaki, M; Izuhara, M; Kawano, K; Otsuki, K | 1 |
| Inada, K; Inoue, Y; Kobayashi, M; Kuriyama, K; Matsui, K; Nishimura, K | 1 |
| Abe, H; Araki, R; Funahashi, H; Ishida, Y; Naono-Nagatomo, K; Takeda, R; Taniguchi, H | 1 |
| Kawada, K; Miyamura, M; Ohta, T; Tanaka, K; Tanaka, S | 1 |
| Fujishiro, H; Iritani, S; Kimura, H; Nakamura, T; Ozaki, N; Torii, Y | 1 |
| Naono-Nagatomo, K | 1 |
| Hiromasa, S | 1 |
| Fourman, LT; Robert Meyer, B | 1 |
| Araki, A; Cho, K; Fukuda, I; Miyamoto, A; Oka, R; Tanaka, H | 1 |
| Hayashino, Y; Honda, M; Kuriyama, A | 1 |
| Asano, M; Hiratani, M; Ishitobi, M; Kosaka, H; Wada, Y | 1 |
| Chung, KF; Ng, TH; Yeung, WF; Yung, KP | 1 |
| Fukumizu, M; Hayashi, M; Ishizaki, A; Kohyama, J; Miyajima, T; Tanaka, H | 1 |
| Dickman, R; Fass, R; Gadam, R; Hershcovici, T; Jha, LK; Maradey-Romero, C; Nasrollah, L; Quan, SF | 1 |
| Bedini, A; Lucarini, S; Mor, M; Rivara, S; Spadoni, G | 1 |
| Kablinger, A; Shah, C | 1 |
| Imai, N | 1 |
| Edmonds, C; Swanoski, M | 1 |
| Kryger, M; Roth, T; Wang-Weigand, S; Zhang, J | 1 |
| Kirby-Long, P; Sateia, MJ; Taylor, JL | 1 |
| Cardinali, DP; Hardeland, R; Pandi-Perumal, SR; Poeggeler, B; Spence, DW; Srinivasan, V; Trakht, I | 1 |
| Elliott, E; Nelson, LA; Reynoldson, JN | 1 |
| Roth, T; Sainati, S; Schwartz, H; Wang-Weigand, S; Zammit, G; Zhang, J | 1 |
| Mini, L; Wang-Weigand, S; Zhang, J | 1 |
| Curran, MP; Simpson, D | 1 |
| Friedman, GD | 1 |
| Kripke, DF | 2 |
| Cardinali, DP; Golombek, DA | 1 |
| Richardson, G; Wang-Weigand, S | 1 |
| Allen, LA; Bienfait, KL; Dobkin, RD; Gara, MA; Marin, H; Menza, M | 1 |
| Richardson, GS; Wang-Weigand, S; Zammit, G; Zhang, J | 1 |
| Lehmann, R; Mayer, G; Partinen, M; Roth-Schechter, B; Staner, C; Wang-Weigand, S | 1 |
| Gross, PK; Nourse, R; Wasser, TE | 1 |
| Peng, X; Rosenthal, M; Wang-Weigand, S; Zammit, G | 1 |
| Cardinali, DP; Hardeland, R; Pandi-Perumal, SR; Poeggeler, B; Spence, DW; Srinivasan, V; Trahkt, I | 1 |
| McCue, M; Mini, L; Ogrinc, F; Wang-Weigand, S | 1 |
| Jakobsen, AB | 1 |
| Brown, GM; Cardinali, DP; Hardeland, R; Moscovitch, A; Pandi-Perumal, SR; Spence, DW; Srinivasan, V | 1 |
| Jiang, P; O'Hara, BF; Striz, M; Wisor, JP | 1 |
| Zammit, G | 1 |
| Miyamoto, M | 2 |
| Dawson, D; Ferguson, SA; Rajaratnam, SM | 1 |
| Hirai, K; Kato, K; Miyamoto, M; Nishikawa, H; Nishiyama, K; Yukuhiro, N | 1 |
| Hang, E; Miller, AR; Nordahl, TE; Schaffer, CB; Schaffer, LC | 1 |
| Keck, PE; Martens, B; McCoy, J; McElroy, SL; Moeller, D; Mori, N; Patel, NC; Winstanley, EL | 1 |
| Al-Shehabi, E; Gehrman, P; Gooneratne, NS; Gurubhagavatula, I; Marie, E; Schwab, R | 1 |
| Hamamura, M; Kuwano, T; Nagata, H; Nishiyama, H; Uchimura, N; Uchiyama, M | 1 |
| Hamamura, M; Hashimoto, T; Kuwano, T; Nagata, H; Ogawa, A; Uchimura, N; Uchiyama, M | 1 |
| Hamamura, M; Hashimoto, T; Nagata, H; Ogawa, A; Uchimura, N; Uchiyama, M | 1 |
| Brown, GM; Brzezinski, A; Cardinali, DP; Pandi-Perumal, SR; Spence, DW; Srinivasan, V | 1 |
| Hinotsu, S; Kawakami, K; Ogawa, A; Urushihara, H | 1 |
| Anderson, BJ; Brower, KJ; Conroy, DA; Kurth, ME; Stein, MD | 1 |
| Roth, T; Wang-Weigand, S; Watissée, M | 1 |
| Brown, GM; Brzezinski, A; Cardinali, DP; Srinivasan, V | 1 |
| Kamikawa, K; Kanemura, T; Kohsaka, M; Kuwahara, H; Mikami, A; Murasaki, M; Ogawa, A; Sugita, Y; Taniguchi, M; Uno, H | 1 |
| Furuya, M; Horiguchi, J; Kunishige, K; Liaury, K; Miyaoka, T; Sadakuni, F; Wake, R | 1 |
| Brown, GM; Brzezinski, A; Othaman, Z; Prasad, A; Srinivasan, V; Zakaria, R | 1 |
| Ito, T | 1 |
| Mishima, K | 1 |
| Liu, J; Wang, LN | 1 |
| Correll, JR; Kaufmann, MW; Lerman, J; Norris, ER; Primelo, RA; Zemanek, KJ | 1 |
| Roth, T; Stubbs, C; Walsh, JK | 1 |
| Bate, G; Buysse, D; Kirkpatrick, P | 1 |
| Erman, M; Sainati, S; Seiden, D; Zammit, G; Zhang, J | 1 |
| McGechan, A; Wellington, K | 1 |
| Cao, C; Karim, A; Tolbert, D | 1 |
| Holcomb, SS | 2 |
| Neubauer, D | 1 |
| Andersen, M; Laustsen, G | 1 |
| Owen, RT | 1 |
| Roth, T; Sainati, S; Seiden, D; Wang-Weigand, S; Zee, P; Zhang, J | 1 |
| Wurtman, R | 1 |
| Bellon, A | 1 |
| Fujiki, N | 1 |
| McDougle, CJ; Posey, DJ; Stigler, KA | 1 |
| Curry, DT; Eisenstein, RD; Walsh, JK | 1 |
| Borja, NL; Daniel, KL | 1 |
| Miyamoto, M; Terao, A | 1 |
| Kryger, M; Roth, T; Wang-Weigand, S | 1 |
| Cardinali, DP; Hardeland, R; Pandi-Perumal, SR; Poeggeler, B; Srinivasan, V | 1 |
| Roth, T; Seiden, D; Wang-Weigand, S; Zhang, J | 1 |
| Tuya, AC | 1 |
| Erman, M; Roth, T; Sainati, S; Wang-Weigand, S; Zammit, G; Zhang, J | 1 |
| Cranwell-Bruce, LA | 1 |
| Mini, LJ; Wang-Weigand, S; Zhang, J | 1 |
| Pulisetty, S; Tariq, SH | 1 |
| Cardinali, DP; Hardeland, R; Pandi-Perumal, SR; Poeggeler, B; Srinivasan, V; Trakht, I | 1 |
37 review(s) available for ramelteon and Chronic Insomnia
| Article | Year |
|---|---|
Efficacy of melatonin and ramelteon for the acute and long-term management of insomnia disorder in adults: A systematic review and meta-analysis.
Topics: Adult; Humans; Indenes; Melatonin; Sleep; Sleep Initiation and Maintenance Disorders | 2023 |
The role of suvorexant in the prevention of delirium during acute hospitalization: A systematic review.
Topics: Aged; Aged, 80 and over; Azepines; Critical Care; Critical Illness; Delirium; Drug Therapy, Combination; Female; Humans; Indenes; Length of Stay; Male; Middle Aged; Orexin Receptor Antagonists; Randomized Controlled Trials as Topic; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Retrospective Studies; Sleep; Sleep Initiation and Maintenance Disorders; Treatment Outcome; Triazoles | 2020 |
[A new strategy of treatment of insomnia in the field of cardiology--potential of ramelteon].
Topics: Benzodiazepines; Humans; Hypertension; Indenes; Sleep; Sleep Initiation and Maintenance Disorders; Treatment Outcome | 2013 |
Ramelteon for the treatment of insomnia in adults: a systematic review and meta-analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Humans; Indenes; Male; Middle Aged; Randomized Controlled Trials as Topic; Receptors, Melatonin; Sleep; Sleep Initiation and Maintenance Disorders; Treatment Outcome; Young Adult | 2014 |
Doxepin for insomnia: a systematic review of randomized placebo-controlled trials.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Doxepin; Drug Therapy, Combination; Female; Humans; Indenes; Male; Middle Aged; Randomized Controlled Trials as Topic; Sleep Initiation and Maintenance Disorders; Treatment Outcome; United States; United States Food and Drug Administration; Young Adult | 2015 |
Pharmacokinetic and pharmacodynamic evaluation of ramelteon : an insomnia therapy.
Topics: Cost of Illness; Humans; Hypnotics and Sedatives; Indenes; Receptors, Melatonin; Sleep Initiation and Maintenance Disorders | 2015 |
A Review of Suvorexant, Doxepin, Ramelteon, and Tasimelteon for the Treatment of Insomnia in Geriatric Patients.
Topics: Aged; Aged, 80 and over; Azepines; Benzofurans; Cyclopropanes; Doxepin; Humans; Hypnotics and Sedatives; Indenes; Randomized Controlled Trials as Topic; Sleep Initiation and Maintenance Disorders; Triazoles | 2017 |
Efficacy and clinical safety of ramelteon: an evidence-based review.
Topics: Animals; Attention; Dose-Response Relationship, Drug; Drug Interactions; Evidence-Based Medicine; Humans; Hypnotics and Sedatives; Indenes; Long-Term Care; Metabolic Clearance Rate; Randomized Controlled Trials as Topic; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sleep Initiation and Maintenance Disorders; Treatment Outcome; Wakefulness | 2008 |
The effect of melatonergic and non-melatonergic antidepressants on sleep: weighing the alternatives.
Topics: Acetamides; Affect; Antidepressive Agents; Brain; Depressive Disorder, Major; Humans; Indenes; Melatonin; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Selective Serotonin Reuptake Inhibitors; Serotonin 5-HT2 Receptor Antagonists; Serotonin Antagonists; Sleep; Sleep Initiation and Maintenance Disorders | 2009 |
Ramelteon: a novel approach in the treatment of insomnia.
Topics: Humans; Hypnotics and Sedatives; Indenes; Sleep Initiation and Maintenance Disorders | 2008 |
Ramelteon: a review of its use in insomnia.
Topics: Administration, Oral; Area Under Curve; Clinical Trials as Topic; Half-Life; Humans; Indenes; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sleep Initiation and Maintenance Disorders; Treatment Outcome | 2008 |
Melatonin and melatonergic drugs on sleep: possible mechanisms of action.
Topics: Acetamides; Aging; Animals; Antidepressive Agents; Circadian Rhythm; Depressive Disorder; Humans; Hypnotics and Sedatives; Indenes; Melatonin; Receptors, Melatonin; Signal Transduction; Sleep; Sleep Initiation and Maintenance Disorders; Suprachiasmatic Nucleus | 2009 |
Effects of ramelteon 8 mg on objective sleep latency in adults with chronic insomnia on nights 1 and 2: pooled analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Female; Humans; Indenes; Male; Middle Aged; Randomized Controlled Trials as Topic; Reaction Time; Receptors, Melatonin; Sleep; Sleep Initiation and Maintenance Disorders; Young Adult | 2009 |
Ramelteon: a review of its therapeutic potential in sleep disorders.
Topics: Animals; Humans; Indenes; Melatonin; Sleep; Sleep Initiation and Maintenance Disorders | 2009 |
Comparative tolerability of newer agents for insomnia.
Topics: Azabicyclo Compounds; Clinical Trials as Topic; Drug Interactions; Humans; Hypnotics and Sedatives; Indenes; Memory; Piperazines; Psychomotor Performance; Pyridines; Randomized Controlled Trials as Topic; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; Substance-Related Disorders; Zolpidem | 2009 |
[A novel therapeutic drug: ramelteon].
Topics: Humans; Indenes; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sleep Initiation and Maintenance Disorders | 2009 |
Melatonin agonists and insomnia.
Topics: Acetamides; Animals; Benzofurans; Circadian Rhythm; Cyclopropanes; Humans; Hypnotics and Sedatives; Indenes; Melatonin; Sleep Initiation and Maintenance Disorders | 2010 |
[Preclinical pharmacological profiles and clinical outcome of the novel melatonin-receptor agonist ramelteon (Rozerem 8 mg).].
Topics: Animals; Chronic Disease; Cyclic AMP; Drug Evaluation, Preclinical; Humans; Indenes; Randomized Controlled Trials as Topic; Receptors, Melatonin; Sleep Initiation and Maintenance Disorders; Sleep Stages; Substance-Related Disorders; Suprachiasmatic Nucleus | 2010 |
Melatonin agonists in primary insomnia and depression-associated insomnia: are they superior to sedative-hypnotics?
Topics: Acetamides; Animals; Benzodiazepines; Benzofurans; Clinical Trials as Topic; Cyclopropanes; Depressive Disorder; Humans; Hypnotics and Sedatives; Indenes; Indoles; Melatonin; Sleep Initiation and Maintenance Disorders | 2011 |
Melatonin and its analogs in insomnia and depression.
Topics: Acetamides; Animals; Depression; Humans; Hypnotics and Sedatives; Indenes; Melatonin; Mice; Sleep Initiation and Maintenance Disorders | 2012 |
Melatonergic drugs for therapeutic use in insomnia and sleep disturbances of mood disorders.
Topics: Animals; Central Nervous System Depressants; Humans; Indenes; Melatonin; Mood Disorders; Sleep Initiation and Maintenance Disorders | 2012 |
[New hypnotics ramelteon for the treatment of insomniacs with circadian rhythm disturbance].
Topics: Chronobiology Disorders; Humans; Hypnotics and Sedatives; Indenes; Male; Sleep Initiation and Maintenance Disorders | 2012 |
Ramelteon in the treatment of chronic insomnia: systematic review and meta-analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Double-Blind Method; Humans; Hypnotics and Sedatives; Indenes; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Sleep Initiation and Maintenance Disorders; Treatment Outcome; Young Adult | 2012 |
Ramelteon.
Topics: Animals; Biotransformation; Clinical Trials as Topic; Drug Interactions; Humans; Indenes; Receptors, Melatonin; Sleep; Sleep Initiation and Maintenance Disorders; Tissue Distribution | 2005 |
Recommendations for assessing insomnia.
Topics: Humans; Hypnotics and Sedatives; Indenes; Mass Screening; Medical History Taking; Nurse Practitioners; Nursing Assessment; Patient Care Planning; Patient Selection; Polysomnography; Primary Health Care; Relaxation Therapy; Risk Factors; Self Care; Sleep Initiation and Maintenance Disorders; Surveys and Questionnaires | 2006 |
Ramelteon (rozerem) a novel approach for insomnia treatment.
Topics: Administration, Oral; Adult; Aged; Albumins; Biological Availability; Drug Interactions; Drug Monitoring; Half-Life; Humans; Indenes; Liver; Middle Aged; Protein Binding; Receptors, Melatonin; Sleep Initiation and Maintenance Disorders; Treatment Outcome | 2006 |
Ramelteon: profile of a new sleep-promoting medication.
Topics: Animals; Drug Interactions; Humans; Hypnotics and Sedatives; Indenes; Randomized Controlled Trials as Topic; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sleep; Sleep Initiation and Maintenance Disorders; Suprachiasmatic Nucleus | 2006 |
Ramelteon: a novel treatment for the treatment of insomnia.
Topics: Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Indenes; Melatonin; Practice Patterns, Physicians'; Receptors, Melatonin; Sleep Initiation and Maintenance Disorders; Treatment Outcome | 2006 |
Searching for new options for treating insomnia: are melatonin and ramelteon beneficial?
Topics: Administration, Intranasal; Adult; Aged; Circadian Rhythm; Female; Humans; Indenes; Injections, Intravenous; Male; Melatonin; Middle Aged; Randomized Controlled Trials as Topic; Sleep; Sleep Initiation and Maintenance Disorders | 2006 |
Pharmacologic management of insomnia: past, present, and future.
Topics: Drug Therapy; Forecasting; Humans; Hypnotics and Sedatives; Indenes; Phytotherapy; Sleep Initiation and Maintenance Disorders | 2006 |
Ramelteon for the treatment of insomnia.
Topics: Adolescent; Adult; Aged; Area Under Curve; Drug Interactions; Economics, Pharmaceutical; Female; Humans; Indenes; Male; Middle Aged; Sleep Initiation and Maintenance Disorders | 2006 |
[Recent and potential drugs for treatment of insomnia].
Topics: Animals; Azabicyclo Compounds; Benzodiazepines; Diphenhydramine; Drug Design; Fluorobenzenes; GABA-A Receptor Agonists; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Indenes; Orexin Receptors; Phenols; Piperazines; Pyridines; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Serotonin 5-HT2 Receptor Antagonists; Sleep Initiation and Maintenance Disorders; Thiophenes; Zolpidem | 2007 |
Drug Insight: the use of melatonergic agonists for the treatment of insomnia-focus on ramelteon.
Topics: Animals; Humans; Indenes; Receptors, Melatonin; Sleep Initiation and Maintenance Disorders | 2007 |
Hypnotic sedative drugs.
Topics: Acetamides; Azabicyclo Compounds; Chemistry, Pharmaceutical; Cost of Illness; Humans; Hypnotics and Sedatives; Indenes; Nurse's Role; Patient Education as Topic; Piperazines; Pyridines; Pyrimidines; Sleep Initiation and Maintenance Disorders; Zolpidem | 2007 |
Pharmacotherapy for insomnia.
Topics: Antidepressive Agents; Azabicyclo Compounds; Central Nervous System Depressants; Eszopiclone; GABA Agonists; GABA-A Receptor Antagonists; Humans; Indenes; Melatonin; Phytotherapy; Piperazines; Pyridines; Sleep Initiation and Maintenance Disorders; Valerian; Zolpidem | 2008 |
[Drugs for insomnia and improving quality of life (QOL): research and development of ramelteon, an MT1/MT2-receptor agonist].
Topics: Animals; Humans; Indenes; Melatonin; Quality of Life; Receptors, Melatonin; Sleep Initiation and Maintenance Disorders | 2008 |
Melatonergic drugs in clinical practice.
Topics: Acetamides; Animals; Antidepressive Agents; Biological Clocks; Humans; Hypnotics and Sedatives; Indenes; Melatonin; Receptors, Melatonin; Sleep Initiation and Maintenance Disorders | 2008 |
28 trial(s) available for ramelteon and Chronic Insomnia
| Article | Year |
|---|---|
Addition of Suvorexant to Ramelteon Therapy for Improved Sleep Quality with Reduced Delirium Risk in Acute Stroke Patients.
Topics: Aged; Aged, 80 and over; Azepines; Delirium; Drug Therapy, Combination; Female; GABA Agonists; Humans; Indenes; Male; Orexin Receptor Antagonists; Receptors, Melatonin; Retrospective Studies; Risk Factors; Sleep; Sleep Aids, Pharmaceutical; Sleep Initiation and Maintenance Disorders; Stroke; Treatment Outcome; Triazoles | 2019 |
[Treatment with ramelteon for sleep disturbance in severely disabled children and young adults].
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Indenes; Male; Melatonin; Sleep; Sleep Initiation and Maintenance Disorders; Sleep Stages; Treatment Outcome; Young Adult | 2013 |
The Effect of Ramelteon on Heartburn Symptoms of Patients With Gastroesophageal Reflux Disease and Chronic Insomnia: A Pilot Study.
Topics: Adult; Aged; Arizona; Double-Blind Method; Female; Gastroesophageal Reflux; Heartburn; Humans; Hypnotics and Sedatives; Indenes; Male; Middle Aged; Pilot Projects; Prospective Studies; Sleep; Sleep Initiation and Maintenance Disorders; Time Factors; Treatment Outcome | 2016 |
The effects of ramelteon on respiration during sleep in subjects with moderate to severe chronic obstructive pulmonary disease.
Topics: Adolescent; Adult; Comorbidity; Cross-Over Studies; Double-Blind Method; Female; Humans; Indenes; Male; Oximetry; Polysomnography; Pulmonary Disease, Chronic Obstructive; Receptors, Melatonin; Severity of Illness Index; Sleep Apnea Syndromes; Sleep Apnea, Obstructive; Sleep Initiation and Maintenance Disorders; Sleep Stages; Young Adult | 2009 |
The effects of ramelteon in a first-night model of transient insomnia.
Topics: Adult; Female; Humans; Indenes; Male; Placebos; Polysomnography; Receptor, Melatonin, MT2; Sleep Initiation and Maintenance Disorders; Treatment Outcome | 2009 |
Effects of long-term exposure to ramelteon, a melatonin receptor agonist, on endocrine function in adults with chronic insomnia.
Topics: Adolescent; Adult; Double-Blind Method; Endocrine System; Female; Follow-Up Studies; Humans; Hypnotics and Sedatives; Indenes; Male; Middle Aged; Prolactin; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sex Factors; Sleep Initiation and Maintenance Disorders; Young Adult | 2009 |
Ramelteon for the treatment of insomnia in menopausal women.
Topics: Adult; Female; Humans; Indenes; Middle Aged; Postmenopause; Receptors, Melatonin; Sleep Initiation and Maintenance Disorders | 2009 |
Safety and subjective sleep effects of ramelteon administration in adults and older adults with chronic primary insomnia: a 1-year, open-label study.
Topics: Adolescent; Adult; Aged; Chronic Disease; Dose-Response Relationship, Drug; Female; Humans; Indenes; Male; Melatonin; Middle Aged; Severity of Illness Index; Single-Blind Method; Sleep Initiation and Maintenance Disorders; Surveys and Questionnaires; Testosterone; Thyroxine; Young Adult | 2009 |
Efficacy and safety of 6-month nightly ramelteon administration in adults with chronic primary insomnia.
Topics: Adolescent; Adult; Aged; Attention; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hypnotics and Sedatives; Indenes; Male; Memory, Short-Term; Middle Aged; Polysomnography; Prospective Studies; Retention, Psychology; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; Treatment Outcome; Wakefulness; Young Adult | 2009 |
Ramelteon for insomnia symptoms in a community sample of adults with generalized anxiety disorder: an open label study.
Topics: Adult; Aged; Anxiety Disorders; Depressive Disorder; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Indenes; Male; Middle Aged; Personality Inventory; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sleep Initiation and Maintenance Disorders; Surveys and Questionnaires | 2009 |
Effect of ramelteon on middle-of-the-night balance in older adults with chronic insomnia.
Topics: Aged; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Indenes; Male; Memory, Short-Term; Mental Recall; Motor Activity; Orientation; Postural Balance; Pyridines; Reaction Time; Sleep Initiation and Maintenance Disorders; Wakefulness; Zolpidem | 2009 |
A randomized, placebo-controlled study of adjunctive ramelteon in ambulatory bipolar I disorder with manic symptoms and sleep disturbance.
Topics: Adult; Bipolar Disorder; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Indenes; Male; Outpatients; Sleep Initiation and Maintenance Disorders | 2011 |
Effectiveness of ramelteon for insomnia symptoms in older adults with obstructive sleep apnea: a randomized placebo-controlled pilot study.
Topics: Age Factors; Aged; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Indenes; Male; Middle Aged; Pilot Projects; Polysomnography; Positive-Pressure Respiration; Reference Values; Risk Assessment; Severity of Illness Index; Sleep Apnea, Obstructive; Sleep Initiation and Maintenance Disorders; Sleep Stages; Time Factors; Treatment Outcome | 2010 |
Evaluation of subjective efficacy and safety of ramelteon in Japanese subjects with chronic insomnia.
Topics: Adult; Aged; Aged, 80 and over; Asian People; Female; Humans; Indenes; Male; Medical Records; Middle Aged; Patient Satisfaction; Placebos; Secondary Prevention; Sleep; Sleep Initiation and Maintenance Disorders; Treatment Outcome; Young Adult | 2011 |
Long-term safety and efficacy of ramelteon in Japanese patients with chronic insomnia.
Topics: Adult; Aged; Aged, 80 and over; Asian People; Drug Tolerance; Endocrine System; Female; Humans; Hypnotics and Sedatives; Indenes; Male; Middle Aged; Placebos; Receptors, Melatonin; Secondary Prevention; Single-Blind Method; Sleep; Sleep Initiation and Maintenance Disorders; Time Factors; Young Adult | 2011 |
Efficacy and safety of ramelteon in Japanese adults with chronic insomnia: a randomized, double-blind, placebo-controlled study.
Topics: Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Indenes; Japan; Male; Placebos; Sleep Initiation and Maintenance Disorders; Time Factors; Treatment Outcome | 2011 |
Night-to-night variability of sleep latency significantly predicts the magnitude of subsequent change in sleep latency during placebo administration.
Topics: Adult; Aged; Circadian Rhythm; Female; Humans; Indenes; Male; Middle Aged; Multivariate Analysis; Placebo Effect; Predictive Value of Tests; Receptors, Melatonin; Sleep; Sleep Initiation and Maintenance Disorders | 2011 |
Use of a post-sleep questionnaire-interactive voice response system (PSQ-IVRS) to evaluate the subjective sleep effects of ramelteon in adults with chronic insomnia.
Topics: Adolescent; Adult; Disorders of Excessive Somnolence; Female; Humans; Indenes; Male; Middle Aged; Placebos; Polysomnography; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Reproducibility of Results; Sleep; Sleep Initiation and Maintenance Disorders; Surveys and Questionnaires; Telecommunications; Young Adult | 2011 |
Efficacy and tolerability of ramelteon in a double-blind, placebo-controlled, crossover study in Japanese patients with chronic primary insomnia.
Topics: Adult; Asian People; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypnotics and Sedatives; Indenes; Male; Middle Aged; Polysomnography; Sleep; Sleep Initiation and Maintenance Disorders; Sleep Stages; Surveys and Questionnaires; Treatment Outcome; Young Adult | 2011 |
A double-blind, randomized, placebo-controlled trial of adjunctive ramelteon for the treatment of insomnia and mood stability in patients with euthymic bipolar disorder.
Topics: Adult; Affect; Antimanic Agents; Bipolar Disorder; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Indenes; Male; Middle Aged; Placebos; Secondary Prevention; Sleep; Sleep Initiation and Maintenance Disorders; Treatment Outcome | 2013 |
Ramelteon (TAK-375), a selective MT1/MT2-receptor agonist, reduces latency to persistent sleep in a model of transient insomnia related to a novel sleep environment.
Topics: Adult; Double-Blind Method; Environment; Female; Humans; Indenes; Male; Middle Aged; Polysomnography; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sleep; Sleep Initiation and Maintenance Disorders; Time Factors | 2005 |
An efficacy, safety, and dose-response study of Ramelteon in patients with chronic primary insomnia.
Topics: Adolescent; Adult; Chronic Disease; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Indenes; Male; Melatonin; Middle Aged; Polysomnography; Sleep Initiation and Maintenance Disorders; Surveys and Questionnaires; Treatment Outcome | 2006 |
Disposition kinetics and tolerance of escalating single doses of ramelteon, a high-affinity MT1 and MT2 melatonin receptor agonist indicated for treatment of insomnia.
Topics: Adult; Aged; Area Under Curve; Attention; Biotransformation; Cognition; Dose-Response Relationship, Drug; Female; Humans; Indenes; Male; Middle Aged; Neuropsychological Tests; Psychomotor Performance; Receptors, Melatonin; Sleep Initiation and Maintenance Disorders | 2006 |
Effects of ramelteon on patient-reported sleep latency in older adults with chronic insomnia.
Topics: Aged; Aged, 80 and over; Chronic Disease; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Female; Humans; Hypnotics and Sedatives; Indenes; Male; Middle Aged; Sleep; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; Surveys and Questionnaires; Time Factors | 2006 |
Safety of ramelteon in individuals with mild to moderate obstructive sleep apnea.
Topics: Adult; Arousal; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Indenes; Male; Middle Aged; Oxygen; Polysomnography; Sleep Apnea, Obstructive; Sleep Initiation and Maintenance Disorders; Sleep Stages; Wakefulness | 2007 |
A 2-night, 3-period, crossover study of ramelteon's efficacy and safety in older adults with chronic insomnia.
Topics: Aged; Aged, 80 and over; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Female; Humans; Indenes; Male; Mental Recall; Placebos; Receptors, Melatonin; Sleep; Sleep Initiation and Maintenance Disorders; Surveys and Questionnaires; Treatment Outcome | 2007 |
Evaluation of the efficacy and safety of ramelteon in subjects with chronic insomnia.
Topics: Adult; Chronic Disease; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypnotics and Sedatives; Indenes; Male; Middle Aged; Polysomnography; Sleep Initiation and Maintenance Disorders; Surveys and Questionnaires; Treatment Outcome | 2007 |
Self-reported efficacy and tolerability of ramelteon 8 mg in older adults experiencing severe sleep-onset difficulty.
Topics: Aged; Chronic Disease; Dizziness; Double-Blind Method; Dysgeusia; Female; Headache; Humans; Hypnotics and Sedatives; Indenes; Male; Muscular Diseases; Pain; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sleep Initiation and Maintenance Disorders; Time Factors | 2007 |
33 other study(ies) available for ramelteon and Chronic Insomnia
| Article | Year |
|---|---|
Circadian periods of sensitivity for ramelteon on the onset of running-wheel activity and the peak of suprachiasmatic nucleus neuronal firing rhythms in C3H/HeN mice.
Topics: Animals; Circadian Rhythm; Indenes; Male; Melatonin; Mice; Mice, Inbred C3H; Motor Activity; Receptors, Melatonin; Running; Sleep Initiation and Maintenance Disorders; Suprachiasmatic Nucleus | 2011 |
MT1 and MT2 melatonin receptors: ligands, models, oligomers, and therapeutic potential.
Topics: Animals; Binding Sites; Depressive Disorder; Humans; Ligands; Melatonin; Models, Molecular; Protein Multimerization; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sleep Initiation and Maintenance Disorders; Structure-Activity Relationship | 2014 |
Prompt improvement of difficulty with sleep initiation and waking up in the morning and daytime somnolence by combination therapy of suvorexant and ramelteon in delayed sleep-wake phase disorder: a case series of three patients.
Topics: Adult; Azepines; Disorders of Excessive Somnolence; Female; Humans; Indenes; Male; Sleep; Sleep Initiation and Maintenance Disorders; Triazoles; Young Adult | 2021 |
The efficacy of add-on ramelteon and subsequent dose reduction in benzodiazepine derivatives/Z-drugs for the treatment of sleep-related eating disorder and night eating syndrome: a retrospective analysis of consecutive patients.
Topics: Benzodiazepines; Drug Tapering; Feeding and Eating Disorders; Humans; Indenes; Night Eating Syndrome; Pharmaceutical Preparations; Retrospective Studies; Sleep; Sleep Initiation and Maintenance Disorders | 2021 |
A survey of the effects of ramelteon on benzodiazepine-dependence: Comparison between a ramelteon add-on group and a continuous benzodiazepine administration group.
Topics: Aged; Benzodiazepines; Female; Humans; Hypnotics and Sedatives; Indenes; Male; Middle Aged; Outcome Assessment, Health Care; Sleep Initiation and Maintenance Disorders; Substance-Related Disorders | 2018 |
Hypochondriasis in the elderly and Lewy body disease.
Topics: Aged; Clonazepam; Humans; Hyperacusis; Hypochondriasis; Indenes; Lewy Body Disease; Magnetic Resonance Imaging; Male; REM Sleep Behavior Disorder; Sleep Initiation and Maintenance Disorders | 2019 |
Response to "Comments on the study: A survey of the effects of ramelteon on benzodiazepine-dependence".
Topics: Benzodiazepines; Humans; Hypnotics and Sedatives; Indenes; Sleep Initiation and Maintenance Disorders; Substance-Related Disorders | 2020 |
Autoimmune hepatitis in association with ramelteon.
Topics: Anti-Inflammatory Agents; Fatal Outcome; Hepatitis, Autoimmune; Humans; Indenes; Liver Function Tests; Male; Middle Aged; Peritonitis; Prednisone; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sleep Initiation and Maintenance Disorders; Ultrasonography | 2013 |
Ramelteon monotherapy for insomnia and impulsive behavior in high-functioning autistic disorder.
Topics: Adolescent; Autistic Disorder; Humans; Impulsive Behavior; Indenes; Male; Sleep Initiation and Maintenance Disorders; Treatment Outcome | 2014 |
[A nationwide survey on the uses of melatonin and ramelteon in Japanese children].
Topics: Adolescent; Adult; Child; Child, Preschool; Circadian Rhythm; Data Collection; Female; Humans; Indenes; Infant; Japan; Male; Melatonin; Sleep; Sleep Initiation and Maintenance Disorders; Young Adult | 2015 |
Ramelteon-induced nightmares: A case report.
Topics: Adult; Amphetamines; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Dreams; Humans; Hypnotics and Sedatives; Indenes; Male; Receptors, Melatonin; Sleep Initiation and Maintenance Disorders | 2015 |
A Cluster Headache Responsive to Ramelteon, a Selective Melatonin MT1/MT2 Receptor Agonist.
Topics: Adult; Cluster Headache; Humans; Indenes; Male; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Receptors, Melatonin; Sleep Initiation and Maintenance Disorders | 2016 |
Ramelteon 8 mg/d versus placebo in patients with chronic insomnia: post hoc analysis of a 5-week trial using 50% or greater reduction in latency to persistent sleep as a measure of treatment effect.
Topics: Adult; Chronic Disease; Female; Humans; Indenes; Male; Randomized Controlled Trials as Topic; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sleep; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; Time Factors | 2008 |
Hypnotics and skin cancer: hint at drug carcinogenesis, coincidence, or benefit of more sleep?
Topics: Acetamides; Animals; Azabicyclo Compounds; Carcinoma, Basal Cell; Eszopiclone; Humans; Indenes; Piperazines; Pyrimidines; Randomized Controlled Trials as Topic; Skin Neoplasms; Sleep Initiation and Maintenance Disorders; United States; United States Food and Drug Administration | 2008 |
Possibility that certain hypnotics might cause cancer in skin.
Topics: Acetamides; Animals; Azabicyclo Compounds; Carcinoma, Basal Cell; Causality; Cross-Sectional Studies; Eszopiclone; Follow-Up Studies; Humans; Hypnotics and Sedatives; Incidence; Indenes; Melanoma; Piperazines; Pyridines; Pyrimidines; Randomized Controlled Trials as Topic; Skin Neoplasms; Sleep Initiation and Maintenance Disorders; United States; United States Food and Drug Administration; Zolpidem | 2008 |
Let there be sleep--on time.
Topics: Circadian Rhythm; Humans; Indenes; Melatonin; Randomized Controlled Trials as Topic; Receptors, Melatonin; Sleep; Sleep Initiation and Maintenance Disorders | 2009 |
[Objection to a conclusion in Medicinske Nyheder].
Topics: Age Factors; Humans; Indenes; Sleep; Sleep Initiation and Maintenance Disorders; Treatment Outcome | 2009 |
Ramelteon: application withdrawn. Ramelteon in insomnia: withdrawal of marketing application in patients' best interests.
Topics: Drug Approval; France; Humans; Hypnotics and Sedatives; Indenes; Marketing of Health Services; Receptors, Melatonin; Sleep Initiation and Maintenance Disorders | 2009 |
Effects of ramelteon and triazolam in a mouse genetic model of early morning awakenings.
Topics: Animals; Circadian Rhythm; Darkness; Disease Models, Animal; Indenes; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Phenotype; Photoperiod; Random Allocation; Receptors, Melatonin; Sleep Initiation and Maintenance Disorders; Time Factors; Tranquilizing Agents; Triazolam; Wakefulness | 2009 |
Efficacy and safety of nonbenzodiazepine hypnotics for chronic insomnia in patients with bipolar disorder.
Topics: Acetamides; Adolescent; Adult; Azabicyclo Compounds; Bipolar Disorder; Eszopiclone; Female; Humans; Hypnotics and Sedatives; Indenes; Male; Piperazines; Pyridines; Pyrimidines; Retrospective Studies; Sleep Initiation and Maintenance Disorders; Treatment Outcome; Zolpidem | 2011 |
Ramelteon and improved insomnia in alcohol-dependent patients: a case series.
Topics: Adult; Alcoholism; Female; Humans; Indenes; Male; Middle Aged; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sleep Initiation and Maintenance Disorders; Treatment Outcome | 2011 |
Augmentation with ramelteon to achieve remission in geriatric major depression.
Topics: Aged; Depressive Disorder, Major; Drug Therapy, Combination; Humans; Indenes; Male; Receptors, Melatonin; Sertraline; Sleep Initiation and Maintenance Disorders | 2012 |
[Delirium, insomnia in hospitalization and ramelteon].
Topics: Delirium; Hospitalization; Humans; Indenes; Melatonin; Sleep Initiation and Maintenance Disorders | 2012 |
Drugs for insomnia.
Topics: Benzodiazepines; Drug Interactions; Histamine Antagonists; Humans; Indenes; Pyridines; Sleep Initiation and Maintenance Disorders; Trazodone; Zolpidem | 2012 |
Ramelteon (Rozerem) for insomnia.
Topics: Humans; Indenes; Melatonin; Receptor, Melatonin, MT1; Sleep Initiation and Maintenance Disorders | 2005 |
Fresh from the pipeline: Ramelteon.
Topics: Animals; Clinical Trials as Topic; Humans; Indenes; Molecular Structure; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Sleep; Sleep Initiation and Maintenance Disorders | 2005 |
Consultation corner. Are the new sleep aids right for you?
Topics: Acetamides; Azabicyclo Compounds; Humans; Hypnotics and Sedatives; Indenes; Piperazines; Pyridines; Pyrimidines; Sleep Initiation and Maintenance Disorders; Zolpidem | 2006 |
Associated Professional Sleep Societies--SLEEP 2006 20th Anniversary Meeting. 17-22 June 2006, Salt Lake City, UT, USA.
Topics: Animals; Citalopram; Histamine Antagonists; Humans; Hypnotics and Sedatives; Indenes; Receptors, Histamine H2; Selective Serotonin Reuptake Inhibitors; Sleep Initiation and Maintenance Disorders; Sleep Wake Disorders | 2006 |
Ramelteon for insomnia in two youths with autistic disorder.
Topics: Adolescent; Autistic Disorder; Child; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Indenes; Male; Sleep Initiation and Maintenance Disorders | 2006 |
Putting insomnia to rest.
Topics: Adult; Humans; Hypnotics and Sedatives; Indenes; Receptors, Melatonin; Sleep Initiation and Maintenance Disorders | 2007 |
The management of insomnia in the older adult.
Topics: Aged; Aged, 80 and over; Anti-Anxiety Agents; Antidepressive Agents; Baths; Exercise; Humans; Hypnotics and Sedatives; Indenes; Male; Mianserin; Mirtazapine; Pyridines; Relaxation Therapy; Sleep Initiation and Maintenance Disorders; Trazodone; Zolpidem | 2007 |
Greater incidence of depression with hypnotic use than with placebo.
Topics: Acetamides; Azabicyclo Compounds; Cross-Sectional Studies; Depressive Disorder, Major; Drug Prescriptions; Eszopiclone; Follow-Up Studies; Humans; Hypnotics and Sedatives; Incidence; Indenes; Long-Term Care; Odds Ratio; Piperazines; Pyridines; Pyrimidines; Randomized Controlled Trials as Topic; Sleep Initiation and Maintenance Disorders; United States; United States Food and Drug Administration; Zolpidem | 2007 |
Putting "sleepdriving" and new safety warning in perspective.
Topics: Automobile Driving; Drug Labeling; Humans; Hypnotics and Sedatives; Indenes; Middle Aged; Psychoses, Substance-Induced; Pyridines; Sleep Initiation and Maintenance Disorders; Somnambulism; Zolpidem | 2007 |