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ramatroban and Innate Inflammatory Response

ramatroban has been researched along with Innate Inflammatory Response in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's5 (71.43)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Breyer, RM; Hata, AN; Lybrand, TP1
Arrighi, JF; Atherall, J; Bernardinelli, G; Chollet, A; Cleva, C; Colovray, V; Crosignani, S; Filinchuk, Y; Gaudet, M; Giachetti, C; Golzio, L; Humbert, Y; Macritchie, J; Maio, M; Martin, T; Missotten, M; Page, P; Pittet, PA; Pupowicz, D; Rocha, C; Scheer, A; Schwarz, MK1
Hu, Y; Lou, HQ; Ying, YF1
Bacon, KB; Gantner, F; Nagao, K; Shichijo, M; Sugimoto, H; Takeshita, K; Yamasaki, T1
Gazi, L; Gyles, SL; Hunter, MG; Pettipher, R; Townsend, E; Wettey, FR; Xue, L1
Alenmyr, L; Andersson, G; Högberg, T; Korsgren, M; Kostenis, E; Mathiesen, JM; Persson, CG; Uller, L; Ulven, T1
Gundel, R; Jesmok, G1

Other Studies

7 other study(ies) available for ramatroban and Innate Inflammatory Response

ArticleYear
Identification of determinants of ligand binding affinity and selectivity in the prostaglandin D2 receptor CRTH2.
    The Journal of biological chemistry, 2005, Sep-16, Volume: 280, Issue:37

    Topics: Alanine; Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding, Competitive; Cell Line; Cell Movement; Chemotactic Factors; Chemotaxis; Cyclic AMP; Dose-Response Relationship, Drug; Eicosanoids; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Glutamic Acid; Humans; Hypersensitivity; Indomethacin; Inflammation; Kinetics; Ligands; Mice; Models, Biological; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Prostaglandins; Protein Binding; Protein Structure, Tertiary; Receptors, G-Protein-Coupled; Receptors, Immunologic; Receptors, Prostaglandin; Tyrosine

2005
Discovery of a new class of potent, selective, and orally bioavailable CRTH2 (DP2) receptor antagonists for the treatment of allergic inflammatory diseases.
    Journal of medicinal chemistry, 2008, Apr-10, Volume: 51, Issue:7

    Topics: Animals; Binding Sites; Caco-2 Cells; Cell Membrane Permeability; Crystallography, X-Ray; Cytochrome P-450 Enzyme Inhibitors; Dogs; Drug Design; Humans; Hypersensitivity; Indoles; Inflammation; Male; Microsomes; Models, Molecular; Molecular Structure; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Receptors, Prostaglandin; Spiro Compounds; Stereoisomerism; Structure-Activity Relationship

2008
[CRTH2 antagonist ameliorates airway inflammation in rats with asthma].
    Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2010, Volume: 39, Issue:1

    Topics: Animals; Asthma; Bronchi; Carbazoles; Inflammation; Male; Ovalbumin; Prostaglandin D2; Random Allocation; Rats; Rats, Sprague-Dawley; Receptors, Immunologic; Receptors, Prostaglandin; Sulfonamides

2010
CRTH2 is a prominent effector in contact hypersensitivity-induced neutrophil inflammation.
    International immunology, 2004, Volume: 16, Issue:7

    Topics: Animals; Carbazoles; Chemokine CXCL1; Chemokines; Chemokines, CXC; Cytokines; Dermatitis, Allergic Contact; Dermatitis, Atopic; Eosinophils; Female; Inflammation; Leukotriene B4; Mice; Mice, Inbred BALB C; Neutrophil Activation; Neutrophils; Platelet Aggregation Inhibitors; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; Signal Transduction; Sulfonamides; Th2 Cells

2004
Prostaglandin D2 causes preferential induction of proinflammatory Th2 cytokine production through an action on chemoattractant receptor-like molecule expressed on Th2 cells.
    Journal of immunology (Baltimore, Md. : 1950), 2005, Nov-15, Volume: 175, Issue:10

    Topics: Base Sequence; Bridged Bicyclo Compounds, Heterocyclic; Carbazoles; Cells, Cultured; Cytokines; DNA; Fatty Acids, Unsaturated; Humans; Hydantoins; Hydrazines; Inflammation; Inflammation Mediators; Interleukin-13; Interleukin-4; Interleukin-5; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; Sulfonamides; Th2 Cells; Up-Regulation

2005
Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation.
    Respiratory research, 2007, Feb-28, Volume: 8

    Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Carbazoles; Cells, Cultured; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Immunization; In Vitro Techniques; Inflammation; Mice; Mice, Inbred BALB C; Prostaglandin Antagonists; Pulmonary Eosinophilia; Radioligand Assay; Receptors, Immunologic; Receptors, Prostaglandin; Sensitivity and Specificity; Sulfonamides

2007
Thromboxane-blocked swine as an experimental model of severe intravascular inflammation and septic shock.
    Shock (Augusta, Ga.), 1995, Volume: 4, Issue:5

    Topics: Animals; Antibodies, Monoclonal; Bronchoconstriction; Capillary Permeability; Carbazoles; Disease Models, Animal; Dose-Response Relationship, Drug; Escherichia coli; Inflammation; Leukocytes; Leukopenia; Lung; Platelet Aggregation Inhibitors; Pulmonary Circulation; Receptors, Thromboxane; Shock, Septic; Sulfonamides; Swine; Thromboxane A2; Tumor Necrosis Factor-alpha; Vasoconstriction

1995