ramatroban and Disease Models, Animal

Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Cytochrome P-450 Enzyme System; Disease Models, Animal; Female; Heterocyclic Compounds, 3-Ring; Humans; Mice; Receptors, Immunologic; Receptors, Prostaglandin; Rhinitis, Allergic, Perennial

Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

Topics: Animals; Brain; Carbazoles; Central Nervous System Agents; Chronic Disease; Corticosterone; Cyclooxygenase 2; Depressive Disorder; Disease Models, Animal; Intramolecular Oxidoreductases; Lipocalins; Lipopolysaccharides; Male; Mice, Inbred BALB C; Mice, Knockout; Norepinephrine; Pituitary Adenylate Cyclase-Activating Polypeptide; Receptors, Immunologic; Receptors, Prostaglandin; RNA, Messenger; Social Behavior; Stress, Psychological; Sulfonamides

Topics: Animals; Anti-Allergic Agents; Carbazoles; Disease Models, Animal; Eosinophils; Female; Immunoglobulin E; Interleukin-16; Mice; Mice, Inbred BALB C; Nasal Mucosa; Ovalbumin; Platelet Aggregation Inhibitors; Rhinitis, Allergic, Perennial; Sulfonamides; Terfenadine

Topics: Animals; Anti-Allergic Agents; Behavior, Animal; Benzoquinones; Carbazoles; Dibenzazepines; Disease Models, Animal; Eosinophils; Female; Heptanoic Acids; Histamine; Histamine H1 Antagonists; Imidazoles; Mice; Mice, Inbred BALB C; Nasal Mucosa; Prostaglandin Antagonists; Receptors, Immunologic; Receptors, Prostaglandin; Receptors, Thromboxane A2, Prostaglandin H2; Rhinitis, Allergic, Seasonal; Severity of Illness Index; Sneezing; Sulfonamides; Th2 Cells

Topics: Administration, Oral; Animals; Animals, Genetically Modified; Bile; Carbazoles; Disease Models, Animal; Enterohepatic Circulation; Glucuronides; Hyperbilirubinemia; Injections, Intravenous; Membrane Transport Proteins; Metabolic Clearance Rate; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane A2, Prostaglandin H2; Species Specificity; Sulfonamides; Thromboxane A2

Topics: Administration, Oral; Animals; Carbazoles; Cetirizine; Conjunctivitis, Allergic; Disease Models, Animal; Edema; Eosinophilia; Histamine H2 Antagonists; Indoles; Leukotriene Antagonists; Male; Membrane Proteins; Ovalbumin; Phenylcarbamates; Pruritus; Rats; Rats, Wistar; Receptors, Histamine H2; Receptors, Leukotriene; Receptors, Thromboxane A2, Prostaglandin H2; Sulfonamides; Tosyl Compounds

Topics: Airway Resistance; Animals; Anti-Allergic Agents; Area Under Curve; Carbazoles; Disease Models, Animal; Guinea Pigs; Indoles; Leukotrienes; Male; Ovalbumin; Phenylcarbamates; Pyrilamine; Rhinitis; Sulfonamides; Terfenadine; Thromboxanes; Tosyl Compounds

Topics: Animals; Carbazoles; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Disease Models, Animal; Electroencephalography; Etodolac; Hypersensitivity; Indoles; Indomethacin; Leukotriene Antagonists; Male; Olfactory Bulb; Ovalbumin; Phenylcarbamates; Rats; Rats, Wistar; Receptors, Thromboxane A2, Prostaglandin H2; Rhinitis; Sneezing; Sulfonamides; Tosyl Compounds

Topics: Animals; Asthma; Bronchial Hyperreactivity; Bronchoalveolar Lavage Fluid; Carbazoles; Cells, Cultured; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Immunization; In Vitro Techniques; Inflammation; Mice; Mice, Inbred BALB C; Prostaglandin Antagonists; Pulmonary Eosinophilia; Radioligand Assay; Receptors, Immunologic; Receptors, Prostaglandin; Sensitivity and Specificity; Sulfonamides

Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta, Thoracic; Blotting, Western; Bridged Bicyclo Compounds, Heterocyclic; Carbazoles; Dibenz(b,f)(1,4)oxazepine-10(11H)-carboxylic acid, 8-chloro-, 2-acetylhydrazide; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Fatty Acids, Unsaturated; Hydrazines; Hypertension; Immunohistochemistry; Naphthalenes; Phenylephrine; Potassium Chloride; Propionates; Prostaglandin Antagonists; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP1 Subtype; Receptors, Thromboxane; Sulfonamides; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Xanthones

Topics: Allergens; Animals; Antigens, Plant; Carbazoles; Cryptomeria; Cytokines; Disease Models, Animal; Eosinophils; Immunoglobulins; Mice; Mice, Inbred BALB C; Mice, Mutant Strains; Nasal Mucosa; Nasal Septum; Plant Proteins; Pollen; Prostaglandin D2; Receptors, Immunologic; Receptors, Prostaglandin; Rhinitis, Allergic, Seasonal; Sulfonamides; Th2 Cells

Topics: Animals; Arteriovenous Shunt, Surgical; Blood Vessel Prosthesis; Carbazoles; Disease Models, Animal; In Vitro Techniques; Male; Papio; Platelet Aggregation Inhibitors; Platelet Count; Polyethylene Terephthalates; Receptors, Thromboxane; Sulfonamides; Thrombosis

Topics: Animals; Carbazoles; Carotid Artery Thrombosis; Disease Models, Animal; Dogs; Male; Platelet Aggregation; Platelet Aggregation Inhibitors; Sulfonamides; Thromboxane A2

Topics: Animals; Antibodies, Monoclonal; Bronchoconstriction; Capillary Permeability; Carbazoles; Disease Models, Animal; Dose-Response Relationship, Drug; Escherichia coli; Inflammation; Leukocytes; Leukopenia; Lung; Platelet Aggregation Inhibitors; Pulmonary Circulation; Receptors, Thromboxane; Shock, Septic; Sulfonamides; Swine; Thromboxane A2; Tumor Necrosis Factor-alpha; Vasoconstriction

Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Carbazoles; Coronary Disease; Coronary Vessels; Disease Models, Animal; Dogs; Hemodynamics; Myocardial Infarction; Prostaglandin Endoperoxides, Synthetic; Sulfonamides; Swine; Thromboxanes; Vasoconstriction