raltegravir-potassium and Syndrome

Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome or drug-induced hypersensitivity is a potentially life-threatening drug hypersensitivity syndrome most commonly associated with anticonvulsants, allopurinol, long-acting sulfonamides, dapsone, and minocycline. In the setting of HIV infection, the antiretroviral medicines abacavir, nevirapine, and efavirenz have all shown well-documented associations with DRESS syndrome. There has only been one case (in a poster presentation) of this syndrome in a patient who was taking raltegravir.

Topics: Drug Hypersensitivity; Eosinophilia; Female; HIV Integrase Inhibitors; Humans; Middle Aged; Pyrrolidinones; Raltegravir Potassium; Syndrome