Page last updated: 2024-08-23

raloxifene hydrochloride and Schizophrenia

raloxifene hydrochloride has been researched along with Schizophrenia in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (2.94)29.6817
2010's28 (82.35)24.3611
2020's5 (14.71)2.80

Authors

AuthorsStudies
Edemann-Callesen, H; Felgel-Farnholz, V; Garthe, A; Hadar, R; Hlusicka, EB; Winter, C1
Kong, L; Li, L; Li, Z; Liu, L; Tang, Y; Wang, Y; Wang, Z1
Brand, BA; de Boer, JN; Grootens, KP; Luykx, JJ; Marcelis, MC; Sommer, IE1
Brand, BA; Hamers, IMH; Sommer, IE; Willemse, EJM1
Du, X; Hill, RA; Hudson, M; Jones, NC; Nakamura, JP; Schroeder, A; Sundram, S1
Cobo, J; Creus, M; Cuadras, D; Franco, J; García-Parés, G; Huerta-Ramos, E; Labad, J; Marcó-García, S; Miquel, E; Núñez, C; Reyes, JC; Usall, J1
Burshtein, S; Davis, JM; Grecu, IG; Hagin, M; Levi, L; Matei, VP; Micluția, I; Noy, A; Păcală, B; Podea, D; Tiugan, A; Weiser, M; Zamora, D1
Dong, X; Li, X; Wang, Q; Wang, Y1
Cai, DB; Grigg, J; Kulkarni, J; Li, XH; Ng, CH; Ning, YP; Ungvari, GS; Wang, XP; Xiang, YT; Yang, XH; Zheng, W; Zhu, XM1
Gogos, A; Sbisa, A; van den Buuse, M1
González-Rodríguez, A; Seeman, MV1
Barbero, JD; Bioque, M; Cobo, J; García-Rizo, C; González-Rodríguez, A; Huerta-Ramos, E; Labad, J; Monreal, JA; Soria, V; Tost, M; Usall, J1
Huerta-Ramos, E; Núñez, C; Ramos, B; Usall, J; Vila, È1
Gavrilidis, E; Gurvich, C; Hudaib, A; Kulkarni, J; Thomas, N; Worsley, R1
Dhandapani, A; Narayanaswamy, JC; Venkatasubramanian, G1
Cobo, J; Huerta-Ramos, E; Iniesta, R; Miquel, E; Ochoa, S; Roca, M; Serrano-Blanco, A; Teba, F; Usall, J1
Akhondzadeh, S; Fatehi, F; Hashempoor, S; Kashani, L; Khodaei-Ardakani, MR; Kianimehr, G; Nazari, A; Rezaei, F1
Huerta-Ramos, E; Miquel, E; Ochoa, S; Roca, M; Usall, J1
Catts, SV; Kindler, J; Lenroot, R; Skilleter, AJ; Weickert, CS; Weickert, TW1
Gogos, A; van den Buuse, M1
Balzan, R; Carr, VJ; Catts, SV; Curtis, J; Galletly, C; Kulkarni, J; Lenroot, R; Liu, D; O'Donnell, M; Pellen, D; Schofield, PR; Short, B; Vercammen, A; Weickert, CS; Weickert, TW; Weinberg, D; Wells, R1
Akhondzadeh, S; Khodaie-Ardakani, MR; Khosravi, M; Mohsenian, A; Nejati, S; Tabrizi, M; Zarinfard, R1
Goyal, A; Tharoor, H1
Cobo, J; Creus, M; Cuadras, D; Franco, J; Huerta-Ramos, E; Labad, J; Miquel, E; Núñez, C; Parés, GG; Reyes, JC; Roca, M; Usall, J1
Gur, RE; Ji, E; Kindler, J; Lenroot, R; Skilleter, AJ; Vercammen, A; Weickert, CS; Weickert, TW; White, C1
Khan, MM1
Berk, M; Davis, SR; Gavrilidis, E; Gilbert, H; Grigg, J; Gurvich, C; Gwini, SM; Kulkarni, J; Warren, A; Worsley, R1
Cobo, J; Creus, M; Garcia-Pares, G; Huerta-Ramos, E; Labad, J; Martorell, L; Miquel, E; Núñez, C; Ortega, L; Rubio-Abadal, E; Usall, J; Vilella, E1
Grigg, J; Kulkarni, J; Worsley, R1
Kindler, J; Lenroot, R; Schofield, PR; Weickert, CS; Weickert, TW1
Berk, M; Davis, SR; de Castella, A; Dodd, S; Fitzgerald, PB; Gavrilidis, E; Gilbert, H; Gurvich, C; Kulkarni, J; Lee, SJ1
Araya, S; Cobo, J; Huerta-Ramos, E; Iniesta, R; Ochoa, S; Roca, M; Serrano-Blanco, A; Teba, F; Usall, J1
Jayaram, N; Rao, NP; Raveendranathan, D; Shivakumar, V; Venkatasubramanian, G1
de Castella, A; Gavrilidis, E; Gilbert, H; Gurvich, C; Kulkarni, J; Marston, N; Mehmedbegovic, F; Mu, L1

Reviews

7 review(s) available for raloxifene hydrochloride and Schizophrenia

ArticleYear
Estradiol and raloxifene as adjunctive treatment for women with schizophrenia: A meta-analysis of randomized, double-blind, placebo-controlled trials.
    Acta psychiatrica Scandinavica, 2023, Volume: 147, Issue:4

    Topics: Antipsychotic Agents; Double-Blind Method; Drug Therapy, Combination; Estradiol; Female; Humans; Postmenopause; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Schizophrenia

2023
Evidence-Based Recommendations for the Pharmacological Treatment of Women with Schizophrenia Spectrum Disorders.
    Current psychiatry reports, 2023, Volume: 25, Issue:11

    Topics: Aged; Antipsychotic Agents; Aripiprazole; Estrogens; Female; Humans; Hyperprolactinemia; Male; Raloxifene Hydrochloride; Schizophrenia

2023
Raloxifene as an adjunctive treatment for postmenopausal women with schizophrenia: a meta-analysis of randomized controlled trials.
    Archives of women's mental health, 2018, Volume: 21, Issue:1

    Topics: Adult; Aged; Estrogen Receptor Modulators; Female; Humans; Middle Aged; Postmenopause; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Schizophrenia

2018
Adjunctive raloxifene for postmenopausal women with schizophrenia: A meta-analysis of randomized, double-blind, placebo-controlled trials.
    Schizophrenia research, 2018, Volume: 197

    Topics: Antipsychotic Agents; Drug Therapy, Combination; Female; Humans; Middle Aged; Outcome Assessment, Health Care; Postmenopause; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Schizophrenia; Selective Estrogen Receptor Modulators

2018
Pharmacotherapy for schizophrenia in postmenopausal women.
    Expert opinion on pharmacotherapy, 2018, Volume: 19, Issue:8

    Topics: Antipsychotic Agents; Female; Humans; Phytoestrogens; Postmenopause; Raloxifene Hydrochloride; Receptors, Estrogen; Schizophrenia; Venous Thromboembolism

2018
Targeting hypothalamic-pituitary-adrenal axis hormones and sex steroids for improving cognition in major mood disorders and schizophrenia: a systematic review and narrative synthesis.
    Psychoneuroendocrinology, 2018, Volume: 93

    Topics: Affective Disorders, Psychotic; Bipolar Disorder; Cognition Disorders; Cognitive Dysfunction; Depressive Disorder, Major; Female; Gonadal Steroid Hormones; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Mifepristone; Mood Disorders; Pituitary-Adrenal System; Pregnenolone; Raloxifene Hydrochloride; Schizophrenia

2018
Neurocognitive, Neuroprotective, and Cardiometabolic Effects of Raloxifene: Potential for Improving Therapeutic Outcomes in Schizophrenia.
    CNS drugs, 2016, Volume: 30, Issue:7

    Topics: Animals; Antipsychotic Agents; Humans; Osteoporosis; Raloxifene Hydrochloride; Schizophrenia; Selective Estrogen Receptor Modulators; Treatment Outcome

2016

Trials

16 trial(s) available for raloxifene hydrochloride and Schizophrenia

ArticleYear
The Direct and Long-Term Effects of Raloxifene as Adjunctive Treatment for Schizophrenia-Spectrum Disorders: A Double-Blind, Randomized Clinical Trial.
    Schizophrenia bulletin, 2023, 11-29, Volume: 49, Issue:6

    Topics: Adult; Antipsychotic Agents; Double-Blind Method; Female; Humans; Infant, Newborn; Male; Postmenopause; Raloxifene Hydrochloride; Schizophrenia; Selective Estrogen Receptor Modulators; Treatment Outcome

2023
Effects of raloxifene on cognition in postmenopausal women with schizophrenia: a 24-week double-blind, randomized, parallel, placebo-controlled trial.
    European archives of psychiatry and clinical neuroscience, 2020, Volume: 270, Issue:6

    Topics: Aged; Antipsychotic Agents; Attention; Cognitive Dysfunction; Double-Blind Method; Drug Therapy, Combination; Executive Function; Female; Humans; Memory Disorders; Middle Aged; Postmenopause; Raloxifene Hydrochloride; Schizophrenia; Selective Estrogen Receptor Modulators; Treatment Outcome

2020
Raloxifene Plus Antipsychotics Versus Placebo Plus Antipsychotics in Severely Ill Decompensated Postmenopausal Women With Schizophrenia or Schizoaffective Disorder: A Randomized Controlled Trial.
    The Journal of clinical psychiatry, 2017, Volume: 78, Issue:7

    Topics: Aged; Antipsychotic Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Middle Aged; Postmenopause; Psychiatric Status Rating Scales; Psychotic Disorders; Raloxifene Hydrochloride; Schizophrenia; Schizophrenic Psychology; Treatment Outcome

2017
Specificity proteins 1 and 4 in peripheral blood mononuclear cells in postmenopausal women with schizophrenia: a 24-week double-blind, randomized, parallel, placebo-controlled trial.
    European archives of psychiatry and clinical neuroscience, 2019, Volume: 269, Issue:8

    Topics: Antipsychotic Agents; Double-Blind Method; Drug Therapy, Combination; Estrogen Antagonists; Female; Humans; Leukocytes, Mononuclear; Middle Aged; Postmenopause; Psychiatric Status Rating Scales; Raloxifene Hydrochloride; Schizophrenia; Sp1 Transcription Factor; Sp4 Transcription Factor

2019
Raloxifene as a treatment for cognition in women with schizophrenia: the influence of menopause status.
    Psychoneuroendocrinology, 2019, Volume: 100

    Topics: Adult; Cognition; Drug Therapy, Combination; Estrogen Replacement Therapy; Female; Humans; Menopause; Middle Aged; Postmenopause; Premenopause; Psychiatric Status Rating Scales; Raloxifene Hydrochloride; Retrospective Studies; Schizophrenia; Schizophrenic Psychology; Selective Estrogen Receptor Modulators; Treatment Outcome

2019
Effects of raloxifene on cognition in postmenopausal women with schizophrenia: a double-blind, randomized, placebo-controlled trial.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2014, Volume: 24, Issue:2

    Topics: Antipsychotic Agents; Attention; Double-Blind Method; Executive Function; Female; Humans; Memory; Middle Aged; Neuropsychological Tests; Postmenopause; Raloxifene Hydrochloride; Schizophrenia; Selective Estrogen Receptor Modulators; Socioeconomic Factors; Time Factors; Treatment Outcome

2014
Raloxifene adjunctive therapy for postmenopausal women suffering from chronic schizophrenia: a randomized double-blind and placebo controlled trial.
    Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2014, Jul-10, Volume: 22

    Topics: Aged; Antipsychotic Agents; Chronic Disease; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Middle Aged; Postmenopause; Psychiatric Status Rating Scales; Raloxifene Hydrochloride; Risperidone; Schizophrenia; Selective Estrogen Receptor Modulators; Treatment Outcome

2014
Selective Estrogen Receptor Modulation Increases Hippocampal Activity during Probabilistic Association Learning in Schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2015, Volume: 40, Issue:10

    Topics: Association Learning; Cross-Over Studies; Double-Blind Method; Female; Hippocampus; Humans; Image Processing, Computer-Assisted; Learning Disabilities; Magnetic Resonance Imaging; Male; Oxygen; Raloxifene Hydrochloride; Receptors, Estrogen; Schizophrenia; Selective Estrogen Receptor Modulators

2015
Adjunctive raloxifene treatment improves attention and memory in men and women with schizophrenia.
    Molecular psychiatry, 2015, Volume: 20, Issue:6

    Topics: Adolescent; Adult; Attention Deficit Disorder with Hyperactivity; Australia; Cross-Over Studies; Double-Blind Method; Estrogen Antagonists; Female; Humans; Longitudinal Studies; Male; Memory Disorders; Middle Aged; Neuropsychological Tests; Patient Compliance; Psychiatric Status Rating Scales; Raloxifene Hydrochloride; Schizophrenia; Sex Characteristics; Statistics, Nonparametric; Treatment Outcome; Young Adult

2015
A Placebo-Controlled Study of Raloxifene Added to Risperidone in Men with Chronic Schizophrenia.
    Acta medica Iranica, 2015, Volume: 53, Issue:6

    Topics: Adult; Antipsychotic Agents; Depression; Double-Blind Method; Drug Therapy, Combination; Humans; Male; Psychiatric Status Rating Scales; Raloxifene Hydrochloride; Risperidone; Schizophrenia; Treatment Outcome; Young Adult

2015
Raloxifene as an Adjunctive Treatment for Postmenopausal Women With Schizophrenia: A 24-Week Double-Blind, Randomized, Parallel, Placebo-Controlled Trial.
    Schizophrenia bulletin, 2016, Volume: 42, Issue:2

    Topics: Aged; Antipsychotic Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Middle Aged; Outcome Assessment, Health Care; Placebos; Postmenopause; Raloxifene Hydrochloride; Schizophrenia; Selective Estrogen Receptor Modulators

2016
Adjunctive selective estrogen receptor modulator increases neural activity in the hippocampus and inferior frontal gyrus during emotional face recognition in schizophrenia.
    Translational psychiatry, 2016, May-03, Volume: 6

    Topics: Adult; Brain Mapping; Cross-Over Studies; Double-Blind Method; Emotions; Face; Female; Frontal Lobe; Hippocampus; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Nerve Net; Raloxifene Hydrochloride; Recognition, Psychology; Schizophrenia; Selective Estrogen Receptor Modulators

2016
Effect of Adjunctive Raloxifene Therapy on Severity of Refractory Schizophrenia in Women: A Randomized Clinical Trial.
    JAMA psychiatry, 2016, Sep-01, Volume: 73, Issue:9

    Topics: Adult; Aged; Antipsychotic Agents; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Female; Humans; Intention to Treat Analysis; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Raloxifene Hydrochloride; Schizophrenia; Schizophrenic Psychology

2016
Raloxifene increases prefrontal activity during emotional inhibition in schizophrenia based on estrogen receptor genotype.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2016, Volume: 26, Issue:12

    Topics: Adolescent; Adult; Cross-Over Studies; Double-Blind Method; Emotions; Estrogen Receptor alpha; Female; Genetic Variation; Genotype; Humans; Inhibition, Psychological; Magnetic Resonance Imaging; Male; Middle Aged; Prefrontal Cortex; Raloxifene Hydrochloride; Schizophrenia; Schizophrenic Psychology; Selective Estrogen Receptor Modulators; Young Adult

2016
Piloting the effective therapeutic dose of adjunctive selective estrogen receptor modulator treatment in postmenopausal women with schizophrenia.
    Psychoneuroendocrinology, 2010, Volume: 35, Issue:8

    Topics: Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Middle Aged; Pilot Projects; Placebos; Postmenopause; Raloxifene Hydrochloride; Schizophrenia; Selective Estrogen Receptor Modulators; Treatment Outcome

2010
Raloxifene as an adjunctive treatment for postmenopausal women with schizophrenia: a double-blind, randomized, placebo-controlled trial.
    The Journal of clinical psychiatry, 2011, Volume: 72, Issue:11

    Topics: Aged; Antipsychotic Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Middle Aged; Placebos; Postmenopause; Psychiatric Status Rating Scales; Raloxifene Hydrochloride; Schizophrenia; Selective Estrogen Receptor Modulators; Treatment Outcome

2011

Other Studies

11 other study(ies) available for raloxifene hydrochloride and Schizophrenia

ArticleYear
Adolescent raloxifene treatment in females prevents cognitive deficits in a neurodevelopmental rodent model of schizophrenia.
    Behavioural brain research, 2023, 03-12, Volume: 441

    Topics: Animals; Behavior, Animal; Cognition; Disease Models, Animal; Female; Humans; Male; Poly I-C; Prenatal Exposure Delayed Effects; Raloxifene Hydrochloride; Rodentia; Schizophrenia

2023
Raloxifene recovers effects of prenatal immune activation on cognitive task-induced gamma power.
    Psychoneuroendocrinology, 2019, Volume: 110

    Topics: Animals; Behavior, Animal; Biological Clocks; Cognition; Disease Models, Animal; Female; Gamma Rhythm; Immune System; Lymphocyte Activation; Male; Mice; Mice, Inbred C57BL; Poly I-C; Pregnancy; Prenatal Exposure Delayed Effects; Psychomotor Performance; Raloxifene Hydrochloride; Schizophrenia

2019
The effect of estrogenic compounds on psychosis-like behaviour in female rats.
    PloS one, 2018, Volume: 13, Issue:3

    Topics: Animals; Apomorphine; Dopamine Agonists; Estradiol; Estrogens; Female; Ovariectomy; Psychotic Disorders; Raloxifene Hydrochloride; Rats; Rats, Long-Evans; Receptors, Dopamine; Schizophrenia; Selective Estrogen Receptor Modulators; Tamoxifen

2018
Adjuvant raloxifene treatment for negative symptoms of schizophrenia.
    Asian journal of psychiatry, 2013, Volume: 6, Issue:3

    Topics: Antipsychotic Agents; Chemotherapy, Adjuvant; Female; Humans; Middle Aged; Raloxifene Hydrochloride; Schizophrenia; Schizophrenic Psychology; Treatment Outcome

2013
The effect of raloxifene on symptoms and cognitive functioning in a postmenopausal schizophrenia patient: a case report.
    Archives of women's mental health, 2015, Volume: 18, Issue:2

    Topics: Antipsychotic Agents; Cognition; Cognition Disorders; Drug Therapy, Combination; Female; Humans; Middle Aged; Postmenopause; Psychiatric Status Rating Scales; Raloxifene Hydrochloride; Schizophrenia; Selective Estrogen Receptor Modulators; Treatment Outcome

2015
Comparing the effects of 17β-oestradiol and the selective oestrogen receptor modulators, raloxifene and tamoxifen, on prepulse inhibition in female rats.
    Schizophrenia research, 2015, Volume: 168, Issue:3

    Topics: Acoustic Stimulation; Animals; Apomorphine; Dopamine Agonists; Dose-Response Relationship, Drug; Estradiol; Estrogens; Female; Ovariectomy; Prepulse Inhibition; Raloxifene Hydrochloride; Random Allocation; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Reflex, Startle; Schizophrenia; Selective Estrogen Receptor Modulators; Tamoxifen

2015
Raloxifene trial in postmenopausal woman with treatment-resistant schizophrenia.
    Archives of women's mental health, 2015, Volume: 18, Issue:5

    Topics: Antipsychotic Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Middle Aged; Postmenopause; Raloxifene Hydrochloride; Schizophrenia; Selective Estrogen Receptor Modulators; Treatment Outcome

2015
Pharmacogenetic study of the effects of raloxifene on negative symptoms of postmenopausal women with schizophrenia: A double-blind, randomized, placebo-controlled trial.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2016, Volume: 26, Issue:10

    Topics: Age of Onset; Aged; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Estrogen Receptor alpha; Female; Genotype; Glucuronosyltransferase; Humans; Middle Aged; Pharmacogenetics; Pharmacogenomic Testing; Polymorphism, Single Nucleotide; Postmenopause; Raloxifene Hydrochloride; Schizophrenia; Schizophrenic Psychology; Selective Estrogen Receptor Modulators

2016
Raloxifene for schizophrenia and symptoms of hyperprolactinaemia?
    The Australian and New Zealand journal of psychiatry, 2017, Volume: 51, Issue:3

    Topics: Antipsychotic Agents; Humans; Hyperprolactinemia; Prolactin; Raloxifene Hydrochloride; Schizophrenia

2017
Beneficial effects of add-on raloxifene in schizophrenia.
    Archives of women's mental health, 2012, Volume: 15, Issue:2

    Topics: Adult; Drug Therapy, Combination; Female; Humans; Raloxifene Hydrochloride; Schizophrenia; Selective Estrogen Receptor Modulators

2012
Hormone modulation: a novel therapeutic approach for women with severe mental illness.
    The Australian and New Zealand journal of psychiatry, 2008, Volume: 42, Issue:1

    Topics: Administration, Cutaneous; Adult; Antimanic Agents; Antipsychotic Agents; Clinical Trials as Topic; Cognition Disorders; Drug Therapy, Combination; Estradiol; Female; Humans; Middle Aged; Psychotic Disorders; Raloxifene Hydrochloride; Schizophrenia; Selective Estrogen Receptor Modulators; Tamoxifen

2008