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raloxifene hydrochloride and Experimental Mammary Neoplasms

raloxifene hydrochloride has been researched along with Experimental Mammary Neoplasms in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19908 (28.57)18.7374
1990's1 (3.57)18.2507
2000's15 (53.57)29.6817
2010's4 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Black, LJ; Clemens, JA; Falcone, JF; Jevnikar, MG; Jones, CD; Peters, MK; Pike, AJ; Thompson, AR1
Enteshari, S; Hashemi-Beni, B; Hassanzadeh, F; Minaiyan, M; Varshosaz, J1
Enteshari, S; Hassanzadeh, F; Minayian, M; Varshosaz, J1
Ilhan, N; Ozercan, IH; Susam, S; Tatar, O1
Goel, AJ; Majumdar, SK1
Balaburski, GM; Dardes, RC; Haddad, B; Johnson, M; Jordan, VC; Kim, H; Klein-Szanto, A; Lee, ES; Liu, H; Ross, EA; Sengupta, S; Zhu, F1
Amari, G; Armani, E; Caruso, PL; Civelli, M; Delcanale, M; Galbiati, E; Ghirardi, S1
Chen, B; Dardes, R; Dowsett, M; Gajdos, C; Johnston, SR; Jordan, VC; Kidwai, N1
Beckett, LA; Degregorio, MW; Gregg, JP; Marchisano-Karpman, C; Read, KC; Wurz, GT; Yu, Q1
Brown, PH; Uray, IP1
Laxmi, YR; Liu, X; Okamoto, K; Okamoto, Y; Sekimoto, M; Shibutani, S; Suzuki, N1
Bennett, DR; Black, LJ; Clemens, JA; Jones, CD1
Jordan, VC2
Green, LR; Newboult, E; Valcaccia, B; Wakeling, AE1
Valcaccia, B; Wakeling, AE1
Anzano, MA; Brown, CC; Driver, CL; Logsdon, DL; Mullen, LT; Peer, CW; Roberts, AB; Shrader, MW; Smith, JM; Sporn, MB1
Cockcroft, N; Dahllund, J; Härkönen, P; Hemminki, K; Kangas, L; Koskinen, M; Laine, A; Peng, Z; Qu, Q; Väänänen, K; Zheng, H1
Carolin, KA; Pass, HA1
O'Regan, RM1
Mamounas, EP1
Adámeková, E; Ahlers, I; Ahlersová, E; Bojková, B; Cermáková, M; Chamilová, M; Kalická, K; Kubatka, P1
Dardes, RC; De Los Reyes, A; Gajdos, C; Jordan, VC; O'Regan, RM; Park, W; Rademaker, AW1
Bentrem, DJ; Craig Jordan, V1
Bentrem, D; Dardes, RC; De Los Reyes, A; Gajdos, C; Jordan, VC; O'Regan, RM; Robinson, SP1
Balakrishnan, A; Edery, M; Imagawa, W; Nandi, S; Richards, J1
Bégin, D; Labrie, F; Luthy, IA1
Gottardis, MM; Jordan, VC1

Reviews

6 review(s) available for raloxifene hydrochloride and Experimental Mammary Neoplasms

ArticleYear
Prevention of breast cancer: current state of the science and future opportunities.
    Expert opinion on investigational drugs, 2006, Volume: 15, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Animals; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Drug Evaluation, Preclinical; Drug Therapy, Combination; Estrogen Receptor Modulators; Estrogens; Female; Forecasting; Humans; Leuprolide; Mammary Neoplasms, Experimental; Mice; Middle Aged; Ovariectomy; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Rats; Retinoids; Selective Estrogen Receptor Modulators; Tamoxifen

2006
Laboratory studies to develop general principles for the adjuvant treatment of breast cancer with antiestrogens: problems and potential for future clinical applications.
    Breast cancer research and treatment, 1983, Volume: 3 Suppl

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Combined Modality Therapy; Disease Models, Animal; Dose-Response Relationship, Drug; Estrogen Antagonists; Female; Half-Life; Humans; Mammary Neoplasms, Experimental; Models, Biological; Piperidines; Pyrrolidines; Raloxifene Hydrochloride; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen; Thiophenes

1983
Prevention of breast cancer.
    Critical reviews in oncology/hematology, 2000, Volume: 33, Issue:3

    Topics: Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Apoptosis; Biological Products; Breast Neoplasms; Breast Neoplasms, Male; Carotenoids; Cathepsin D; Cell Adhesion Molecules; Cell Cycle; Clinical Trials, Phase III as Topic; Drug Screening Assays, Antitumor; Estrogens, Non-Steroidal; Female; Fenretinide; Genetic Predisposition to Disease; Hormone Antagonists; Humans; Isoflavones; Male; Mammary Neoplasms, Experimental; Mastectomy; Mice; Middle Aged; Neovascularization, Pathologic; Ovariectomy; Phytoestrogens; Plant Preparations; Raloxifene Hydrochloride; Rats; Retinoids; Risk Assessment; Risk Factors; Selenium; Tamoxifen; Terpenes

2000
Chemoprevention of breast cancer.
    Cancer treatment and research, 2000, Volume: 103

    Topics: Adult; Aged; Animals; Anticarcinogenic Agents; Bone and Bones; Breast Diseases; Breast Neoplasms; Cardiovascular Diseases; Chemotherapy, Adjuvant; Clinical Trials as Topic; Endometrial Neoplasms; Estrogens; Female; Gonadal Steroid Hormones; Humans; Lipids; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Middle Aged; Multicenter Studies as Topic; Neoplasms, Hormone-Dependent; Neoplasms, Second Primary; Neoplastic Syndromes, Hereditary; Osteoporosis, Postmenopausal; Pilot Projects; Precancerous Conditions; Premenopause; Prospective Studies; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Receptors, Estrogen; Reproductive History; Risk Factors; Safety; Selective Estrogen Receptor Modulators; Tamoxifen

2000
Breast cancer chemoprevention.
    Hematology/oncology clinics of North America, 2000, Volume: 14, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Animals; Anticarcinogenic Agents; Breast Neoplasms; Carcinoma; Clinical Trials as Topic; Double-Blind Method; Endometrial Neoplasms; Estrogen Antagonists; Europe; Female; Humans; Hyperlipidemias; Hysterectomy; Mammary Neoplasms, Experimental; Menopause; Mice; Mice, Nude; Middle Aged; Neoplasms, Second Primary; Neoplastic Syndromes, Hereditary; Osteoporosis; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Receptors, Estrogen; Risk Factors; Tamoxifen; United States

2000
Tamoxifen, raloxifene and the prevention of breast cancer.
    Minerva endocrinologica, 2002, Volume: 27, Issue:2

    Topics: Adult; Animals; Antineoplastic Agents, Hormonal; Breast Neoplasms; Carcinoma; Coronary Disease; Drug Design; Endometrial Neoplasms; Estrogens; Female; Humans; Incidence; Mammary Neoplasms, Experimental; Middle Aged; Multicenter Studies as Topic; Neoplasms, Hormone-Dependent; Osteoporosis; Prospective Studies; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Structure-Activity Relationship; Tamoxifen

2002

Other Studies

22 other study(ies) available for raloxifene hydrochloride and Experimental Mammary Neoplasms

ArticleYear
Antiestrogens. 2. Structure-activity studies in a series of 3-aroyl-2-arylbenzo[b]thiophene derivatives leading to [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl] [4-[2-(1-piperidinyl)ethoxy]-phenyl]methanone hydrochloride (LY156758), a remarkably effec
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:8

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Piperidines; Raloxifene Hydrochloride; Rats; Receptors, Estrogen; Structure-Activity Relationship; Uterus

1984
Tissue Distribution and Systemic Toxicity Evaluation of Raloxifene Targeted Polymeric Micelles of Poly (Styrene-Maleic Acid)-Poly (Amide- Ether-Ester-Imide)-Poly (Ethylene Glycol) Loaded With Docetaxel in Breast Cancer Bearing Mice.
    Recent patents on anti-cancer drug discovery, 2019, Nov-21, Volume: 14, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Docetaxel; Drug Carriers; Female; Humans; Maleates; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Micelles; Polyethylene Glycols; Polystyrenes; Raloxifene Hydrochloride; Random Allocation; Selective Estrogen Receptor Modulators; Tissue Distribution

2019
Antitumor activity of raloxifene-targeted poly(styrene maleic acid)-poly (amide-ether-ester-imide) co-polymeric nanomicelles loaded with docetaxel in breast cancer-bearing mice.
    Investigational new drugs, 2018, Volume: 36, Issue:2

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Docetaxel; Female; Kaplan-Meier Estimate; Maleates; Mammary Neoplasms, Experimental; Mice, Inbred BALB C; Micelles; Nanoparticles; Polystyrenes; Raloxifene Hydrochloride; Tumor Burden

2018
Is there any potential anticancer effect of raloxifene and fluoxetine on DMBA-induced rat breast cancer?
    Journal of biochemical and molecular toxicology, 2019, Volume: 33, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Antineoplastic Agents; Body Weight; Carcinogens; Enzyme-Linked Immunosorbent Assay; Female; Fluoxetine; Mammary Neoplasms, Experimental; Raloxifene Hydrochloride; Rats; Rats, Wistar; Weight Gain

2019
Antitumorigenic effects of tamoxifen, raloxifene and the combination on the development of breast tumors induced by mouse mammary carcinoma cells in balb/c-J female mice.
    Journal of chemotherapy (Florence, Italy), 2009, Volume: 21, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Raloxifene Hydrochloride; Survival Rate; Tamoxifen; Tumor Cells, Cultured

2009
Raloxifene-stimulated experimental breast cancer with the paradoxical actions of estrogen to promote or prevent tumor growth: a unifying concept in anti-hormone resistance.
    International journal of oncology, 2010, Volume: 37, Issue:2

    Topics: Animals; Antineoplastic Agents, Hormonal; Carcinoma; Cell Line, Tumor; Cell Proliferation; Drug Interactions; Drug Resistance, Neoplasm; Estrogen Antagonists; Estrogens; Female; Humans; Mammary Neoplasms, Experimental; Mice; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Xenograft Model Antitumor Assays

2010
Pharmacological actions of a novel, potent, tissue-selective benzopyran estrogen.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Benzopyrans; Bone Density; Dose-Response Relationship, Drug; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Humans; Mammary Neoplasms, Experimental; Molecular Structure; Organ Size; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Uterus

2002
Potential of endogenous estrogen receptor beta to influence the selective ER modulator ERbeta complex.
    International journal of oncology, 2005, Volume: 27, Issue:2

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA, Complementary; Drug Resistance, Neoplasm; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Gene Expression Regulation, Neoplastic; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation, Missense; Ovariectomy; Raloxifene Hydrochloride; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Selective Estrogen Receptor Modulators; Sequence Analysis, DNA; Tamoxifen; Transfection; Xenograft Model Antitumor Assays

2005
Ospemifene inhibits the growth of dimethylbenzanthracene-induced mammary tumors in Sencar mice.
    The Journal of steroid biochemistry and molecular biology, 2005, Volume: 97, Issue:3

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinoma; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred SENCAR; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen

2005
Increased antitumor potential of the raloxifene prodrug, raloxifene diphosphate.
    International journal of cancer, 2008, May-01, Volume: 122, Issue:9

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Antineoplastic Agents, Hormonal; Biological Availability; Breast Neoplasms; Carcinogens; Cell Line, Tumor; Cell Proliferation; Estrogen Receptor Modulators; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Organophosphates; Phosphorylation; Prodrugs; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Transplantation, Heterologous

2008
Effects of a new antiestrogen, keoxifene (LY156758), on growth of carcinogen-induced mammary tumors and on LH and prolactin levels.
    Life sciences, 1983, Jun-20, Volume: 32, Issue:25

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Castration; Drug Evaluation, Preclinical; Estradiol; Estrogen Antagonists; Female; Luteinizing Hormone; Mammary Neoplasms, Experimental; Piperidines; Prolactin; Raloxifene Hydrochloride; Rats; Rats, Inbred Strains; Tamoxifen

1983
Non-steroidal antioestrogens--receptor binding and biological response in rat uterus, rat mammary carcinoma and human breast cancer cells.
    Journal of steroid biochemistry, 1984, Volume: 20, Issue:1

    Topics: Animals; Breast Neoplasms; Cell Line; Estrogen Antagonists; Female; Humans; Mammary Neoplasms, Experimental; Piperidines; Pyrrolidines; Raloxifene Hydrochloride; Rats; Receptors, Estrogen; Tamoxifen; Thiophenes; Uterus

1984
Antioestrogenic and antitumour activities of a series of non-steroidal antioestrogens.
    The Journal of endocrinology, 1983, Volume: 99, Issue:3

    Topics: Animals; Estradiol; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Organ Size; Piperidines; Pyrrolidines; Raloxifene Hydrochloride; Rats; Rats, Inbred Strains; Tamoxifen; Thiophenes; Uterus

1983
Chemoprevention of mammary carcinogenesis in the rat: combined use of raloxifene and 9-cis-retinoic acid.
    Journal of the National Cancer Institute, 1996, Jan-17, Volume: 88, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Tretinoin

1996
Selective estrogenic effects of a novel triphenylethylene compound, FC1271a, on bone, cholesterol level, and reproductive tissues in intact and ovariectomized rats.
    Endocrinology, 2000, Volume: 141, Issue:2

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Bone and Bones; Breast Neoplasms; Cholesterol; Estrogen Antagonists; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Organ Size; Osteoporosis; Ovariectomy; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Reference Values; Tamoxifen; Toremifene; Transplantation, Heterologous; Tumor Cells, Cultured; Uterus

2000
Preventive effects of raloxifene and melatonin in N-methyl-N-nitrosourea-induced mammary carcinogenesis in female rats.
    Neoplasma, 2001, Volume: 48, Issue:4

    Topics: Animals; Anticarcinogenic Agents; Body Weight; Drinking; Eating; Female; Kinetics; Mammary Neoplasms, Experimental; Melatonin; Methylnitrosourea; Organ Size; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Uterus

2001
Chemoprevention with antiestrogens: the beginning of the end for breast cancer. Daniel G. Miller Lecture.
    Annals of the New York Academy of Sciences, 2001, Volume: 952

    Topics: Amino Acid Substitution; Animals; Anticarcinogenic Agents; Breast Neoplasms; Clinical Trials as Topic; Drug Design; Estrogen Receptor alpha; Estrogen Receptor Modulators; Estrogens; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Neoplasms, Hormone-Dependent; Osteoporosis, Postmenopausal; Ovariectomy; Raloxifene Hydrochloride; Rats; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Structure-Activity Relationship; Tamoxifen; Tumor Cells, Cultured

2001
Effects of raloxifene after tamoxifen on breast and endometrial tumor growth in athymic mice.
    Journal of the National Cancer Institute, 2002, Feb-20, Volume: 94, Issue:4

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Endometrial Neoplasms; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Neoplasm Transplantation; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen; Transplantation, Heterologous; Tumor Cells, Cultured

2002
Effects of a new clinically relevant antiestrogen (GW5638) related to tamoxifen on breast and endometrial cancer growth in vivo.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:6

    Topics: Animals; Cinnamates; Endometrial Neoplasms; Estrogen Antagonists; Estrogens; Female; Humans; Mammary Neoplasms, Experimental; Mice; Mice, Nude; Neoplasm Transplantation; Raloxifene Hydrochloride; Receptors, Estrogen; Stilbenes; Tamoxifen; Transplantation, Heterologous; Tumor Cells, Cultured

2002
The lack of effect of phenol red or estradiol on the growth response of human, rat, and mouse mammary cells in primary culture.
    Endocrinology, 1988, Volume: 123, Issue:3

    Topics: Animals; Breast; Breast Neoplasms; Cell Division; Cells, Cultured; Epidermal Growth Factor; Estradiol; Estrogen Antagonists; Female; Humans; Kinetics; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Phenolphthaleins; Phenolsulfonphthalein; Piperidines; Prolactin; Raloxifene Hydrochloride; Rats; Rats, Inbred Lew; Receptors, Progesterone; Species Specificity; Tumor Cells, Cultured

1988
Mediation by the androgen receptor of the stimulatory and antiandrogenic actions of 17 beta-estradiol on the growth of androgen-sensitive Shionogi mammary carcinoma cells in culture.
    Endocrinology, 1988, Volume: 123, Issue:3

    Topics: Androgen Antagonists; Animals; Cell Division; Cell Line; Diethylstilbestrol; Dihydrotestosterone; Estradiol; Estrogen Antagonists; Kinetics; Male; Mammary Neoplasms, Experimental; Mice; Piperidines; Raloxifene Hydrochloride; Receptors, Androgen; Testosterone

1988
Antitumor actions of keoxifene and tamoxifen in the N-nitrosomethylurea-induced rat mammary carcinoma model.
    Cancer research, 1987, Aug-01, Volume: 47, Issue:15

    Topics: Animals; Dose-Response Relationship, Drug; Estrogen Antagonists; Female; Mammary Neoplasms, Experimental; Methylnitrosourea; Neoplasms, Hormone-Dependent; Organ Size; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Inbred Strains; Receptors, Estrogen; Tamoxifen; Time Factors; Uterus

1987