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raloxifene hydrochloride and Cancer of Prostate

raloxifene hydrochloride has been researched along with Cancer of Prostate in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (14.29)18.2507
2000's11 (52.38)29.6817
2010's6 (28.57)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Amodeo, P; Arroyo, FJ; Bianchini, G; De Petrocellis, L; López-Alvarado, P; Martín, MA; Menéndez, JC; Orlando, P; Roncero, C; Sánchez, A; Schiano Moriello, A; Vitale, RM1
Tong, D1
Aquino, AM; de Freitas, ATAG; Delella, FK; Gonçalves, BF; Justulin, LA; Mendes, LO; Pinho, CF; Salata, GC; Scarano, WR1
Kapoor, S1
Crippa, V; Messi, E; Piccolella, M; Poletti, A; Tetel, MJ1
Casa, AJ; Cui, X; Dearth, RK; Lee, AV; Litzenburger, BC1
Alexi, X; Alexis, MN; Fokialakis, N; Haroutounian, SA; Kasiotis, KM; Lambrinidis, G; Meligova, AK; Mikros, E1
Abbondanza, C; Bellastella, A; Bellastella, G; Chieffi, P; De Bellis, A; De Rosa, C; Della Ragione, F; Maione, L; Prezioso, D; Rossi, V; Sinisi, AA; Visconti, D1
Clarke, BL; Khosla, S1
Hong, YJ; Kim, BC; Kim, HT; Kim, IY; Kim, SJ; Lee, DK; Morton, RA; Seo, JM; Seong, DH1
Fallon, MA; Finkelstein, JS; Lee, H; Smith, MR1
Chen, Y; Imaida, K; Kakehi, Y; Matsuda, Y; Saoo, K; Takeuchi, H; Yamakawa, K; Yokohira, M; Zeng, Y1
Agus, DB; Bender, LI; Cinman, N; Galkin, AV; Green, L; Gross, M; Holden, S; Jain, A; Kaplan, L; Natale, RB; Nguyen, KN; Shazer, RL1
Dunn, BK; Ford, LG1
González Macías, J; Olmos Martínez, JM1
Kong, CZ; Zhang, YX1
Best, KL; Counts, DF; Goode, RL; Hoover, DM; Jones, CD; Merriman, RL; Neubauer, BL; Sarosdy, MF; Shaar, CJ; Tanzer, LR1
Ziegler, J1
Kim, BC; Kim, IY; Kim, SJ; Leach, F; Lee, DK; Morton, RA; Remaley, AT; Seong, DH1
de Launoit, Y; Dufour, M; Labrie, F; Simard, J; Veilleux, R1

Reviews

5 review(s) available for raloxifene hydrochloride and Cancer of Prostate

ArticleYear
Selective estrogen receptor modulators contribute to prostate cancer treatment by regulating the tumor immune microenvironment.
    Journal for immunotherapy of cancer, 2022, Volume: 10, Issue:4

    Topics: Estradiol; Estrogen Receptor beta; Humans; Male; Prostatic Neoplasms; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tumor Microenvironment

2022
The type I insulin-like growth factor receptor pathway: a key player in cancer therapeutic resistance.
    Frontiers in bioscience : a journal and virtual library, 2008, May-01, Volume: 13

    Topics: Antineoplastic Agents; Breast Neoplasms; Drug Resistance, Neoplasm; Estradiol; Female; Fulvestrant; Humans; Male; Neoplasms; Prostatic Neoplasms; Raloxifene Hydrochloride; Receptor, IGF Type 1; Selective Estrogen Receptor Modulators; Signal Transduction; Treatment Outcome

2008
Modulators of androgen and estrogen receptor activity.
    Critical reviews in eukaryotic gene expression, 2010, Volume: 20, Issue:4

    Topics: Androgen Receptor Antagonists; Breast Neoplasms; Clinical Trials as Topic; Female; Humans; Male; Osteoporosis; Prostatic Neoplasms; Raloxifene Hydrochloride; Receptors, Androgen; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen

2010
Hormonal interventions to prevent hormonal cancers: breast and prostate cancers.
    European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP), 2007, Volume: 16, Issue:3

    Topics: Androgen Receptor Antagonists; Antineoplastic Agents, Hormonal; Breast Neoplasms; Female; Finasteride; Humans; Male; Primary Prevention; Prostatic Neoplasms; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen

2007
[Osteoporosis in cancer survivors].
    Medicina clinica, 2007, Nov-10, Volume: 129, Issue:17

    Topics: Age Factors; Aged; Antineoplastic Agents; Bone Density; Bone Density Conservation Agents; Breast Neoplasms; Drug-Related Side Effects and Adverse Reactions; Female; Fractures, Bone; Humans; Hypogonadism; Male; Middle Aged; Neoplasms; Osteoporosis; Prostatic Neoplasms; Radiotherapy; Raloxifene Hydrochloride; Retrospective Studies; Risk Factors

2007

Trials

2 trial(s) available for raloxifene hydrochloride and Cancer of Prostate

ArticleYear
Raloxifene to prevent gonadotropin-releasing hormone agonist-induced bone loss in men with prostate cancer: a randomized controlled trial.
    The Journal of clinical endocrinology and metabolism, 2004, Volume: 89, Issue:8

    Topics: Aged; Biomarkers; Bone Density; Bone Remodeling; Double-Blind Method; Gonadotropin-Releasing Hormone; Humans; Male; Middle Aged; Osteoporosis; Prostatic Neoplasms; Pulmonary Embolism; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Testosterone

2004
Raloxifene, an oestrogen-receptor-beta-targeted therapy, inhibits androgen-independent prostate cancer growth: results from preclinical studies and a pilot phase II clinical trial.
    BJU international, 2006, Volume: 97, Issue:4

    Topics: Aged; Aged, 80 and over; Animals; Humans; Immunohistochemistry; Male; Mice; Middle Aged; Pilot Projects; Prostate-Specific Antigen; Prostatic Neoplasms; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Treatment Outcome

2006

Other Studies

14 other study(ies) available for raloxifene hydrochloride and Cancer of Prostate

ArticleYear
Tetrahydroisoquinoline-Derived Urea and 2,5-Diketopiperazine Derivatives as Selective Antagonists of the Transient Receptor Potential Melastatin 8 (TRPM8) Channel Receptor and Antiprostate Cancer Agents.
    Journal of medicinal chemistry, 2016, 06-23, Volume: 59, Issue:12

    Topics: Animals; Antineoplastic Agents; Calcium; Cell Proliferation; Diketopiperazines; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Male; Mice; Mice, Inbred C57BL; Molecular Structure; Prostatic Neoplasms; Structure-Activity Relationship; Tetrahydroisoquinolines; TRPM Cation Channels; Tumor Cells, Cultured; Urea

2016
Raloxifene decreases cell viability and migratory potential in prostate cancer cells (LNCaP) with GPR30/GPER1 involvement.
    The Journal of pharmacy and pharmacology, 2019, Volume: 71, Issue:7

    Topics: Cell Line, Tumor; Cell Movement; Cell Survival; Humans; Male; MAP Kinase Signaling System; Middle Aged; Prostate; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Raloxifene Hydrochloride; Receptors, Estrogen; Receptors, G-Protein-Coupled; Signal Transduction

2019
Beyond breast carcinomas: the attenuating effect on tumor growth in other systemic malignancies by raloxifene.
    European journal of clinical nutrition, 2013, Volume: 67, Issue:6

    Topics: Antineoplastic Agents; Bone Density Conservation Agents; Cell Line, Tumor; Colorectal Neoplasms; Female; Humans; Male; Prostatic Neoplasms; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tumor Burden

2013
Modulators of estrogen receptor inhibit proliferation and migration of prostate cancer cells.
    Pharmacological research, 2014, Volume: 79

    Topics: Antineoplastic Agents; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Proliferation; Curcumin; Estradiol; Estrogen Receptor beta; Estrogen Receptor Modulators; Fulvestrant; Genistein; Humans; Male; Prostatic Neoplasms; Raloxifene Hydrochloride; Tamoxifen

2014
Differential estrogen receptor subtype modulators: assessment of estrogen receptor subtype-binding selectivity and transcription-regulating properties of new cycloalkyl pyrazoles.
    The Journal of steroid biochemistry and molecular biology, 2009, Volume: 117, Issue:4-5

    Topics: Adenocarcinoma; Binding Sites; Cell Line, Tumor; Estradiol; Humans; Male; Models, Molecular; Prostatic Neoplasms; Pyrazoles; Raloxifene Hydrochloride; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Transcription, Genetic

2009
Raloxifene induces cell death and inhibits proliferation through multiple signaling pathways in prostate cancer cells expressing different levels of estrogen receptor α and β.
    Journal of cellular physiology, 2011, Volume: 226, Issue:5

    Topics: Antineoplastic Agents, Hormonal; Apoptosis; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Dihydrotestosterone; Dose-Response Relationship, Drug; Enzyme Activation; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Gene Expression Regulation, Neoplastic; Humans; Male; Metallothionein; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Proto-Oncogene Proteins c-myc; Raloxifene Hydrochloride; Receptors, Thrombin; RNA, Messenger; Selective Estrogen Receptor Modulators; Signal Transduction; Time Factors; Transcription, Genetic

2011
Raloxifene, a mixed estrogen agonist/antagonist, induces apoptosis in androgen-independent human prostate cancer cell lines.
    Cancer research, 2002, Sep-15, Volume: 62, Issue:18

    Topics: Apoptosis; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tumor Cells, Cultured

2002
Inhibition of prostate carcinogenesis in probasin/SV40 T antigen transgenic rats by raloxifene, an antiestrogen with anti-androgen action, but not nimesulide, a selective cyclooxygenase-2 inhibitor.
    Carcinogenesis, 2005, Volume: 26, Issue:6

    Topics: Adenocarcinoma; Androgen Antagonists; Androgen-Binding Protein; Animals; Animals, Genetically Modified; Antigens, Polyomavirus Transforming; Apoptosis; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Male; Prostaglandin-Endoperoxide Synthases; Prostatic Neoplasms; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Sulfonamides; Testosterone

2005
Raloxifene can benefit prostate cancer.
    Health news (Waltham, Mass.), 2006, Volume: 12, Issue:8

    Topics: Antineoplastic Agents, Hormonal; Disease Progression; Humans; Male; Prostatic Neoplasms; Raloxifene Hydrochloride

2006
[The role of mitogen-activated protein kinase cascades in inhibition of proliferation in human prostate carcinoma cells by raloxifene: an in vitro experiment].
    Zhonghua yi xue za zhi, 2008, Jan-22, Volume: 88, Issue:4

    Topics: Apoptosis; Blotting, Western; Bone Density Conservation Agents; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Enzyme Inhibitors; Flavonoids; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Male; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Pyridines; Raloxifene Hydrochloride; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction

2008
Raloxifene (LY156758) produces antimetastatic responses and extends survival in the PAIII rat prostatic adenocarcinoma model.
    The Prostate, 1995, Volume: 27, Issue:4

    Topics: Adenocarcinoma; Adrenal Glands; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Fluorouracil; Incidence; Lung Neoplasms; Lymphatic Metastasis; Male; Organ Size; Piperidines; Prostate; Prostatic Neoplasms; Raloxifene Hydrochloride; Random Allocation; Rats; Rats, Wistar; Survival Rate; Testis; Weight Gain

1995
Raloxifene, retinoids, and lavender: "me too" tamoxifen alternatives under study.
    Journal of the National Cancer Institute, 1996, Aug-21, Volume: 88, Issue:16

    Topics: Antineoplastic Agents, Hormonal; Breast Neoplasms; Clinical Trials as Topic; Drugs, Investigational; Estrogen Antagonists; Female; Humans; Lavandula; Male; Neoplasms; Oils, Volatile; Ovarian Neoplasms; Piperidines; Plant Oils; Plants, Medicinal; Prostatic Neoplasms; Raloxifene Hydrochloride; Retinoids; Tamoxifen; Toremifene

1996
Raloxifene, a selective estrogen receptor modulator, induces apoptosis in androgen-responsive human prostate cancer cell line LNCaP through an androgen-independent pathway.
    Cancer research, 2002, Jul-01, Volume: 62, Issue:13

    Topics: Androgens; Apoptosis; Dose-Response Relationship, Drug; Humans; Male; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Raloxifene Hydrochloride; Receptors, Androgen; Selective Estrogen Receptor Modulators; Tumor Cells, Cultured

2002
Characteristics of the biphasic action of androgens and of the potent antiproliferative effects of the new pure antiestrogen EM-139 on cell cycle kinetic parameters in LNCaP human prostatic cancer cells.
    Cancer research, 1991, Oct-01, Volume: 51, Issue:19

    Topics: Androgens; Androstane-3,17-diol; Binding, Competitive; Cell Cycle; Dihydrotestosterone; Dose-Response Relationship, Drug; Drug Antagonism; Estradiol; Estrogen Antagonists; Estrone; Flow Cytometry; Flutamide; Humans; In Vitro Techniques; Male; Metribolone; Piperidines; Prostatic Neoplasms; Raloxifene Hydrochloride; Tamoxifen; Testosterone; Time Factors; Tumor Cells, Cultured

1991