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raloxifene hydrochloride and Bone Loss, Osteoclastic

raloxifene hydrochloride has been researched along with Bone Loss, Osteoclastic in 86 studies

Research

Studies (86)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's12 (13.95)18.2507
2000's52 (60.47)29.6817
2010's21 (24.42)24.3611
2020's1 (1.16)2.80

Authors

AuthorsStudies
Gong, L; Qian, HJ; Tan, MS; Yang, N; Zhang, LK; Zhang, YY1
Allen, MR; Alvarez, MB; Bidwell, JP; Burr, DB; Childress, P; Condon, KW; Davis, H; He, Y; Hernandez-Buquer, S; Plotkin, LI; Robling, AG; Shao, Y; Stayrook, KR; Warden, SJ; Wek, RC; Yang, FC1
Bi, DD; Guo, YF; Han, MH; Hao, T; Liu, H; Qi, XY; Wang, XG; Wang, XT; Zhang, BX1
Eastell, R; Finigan, J; Naylor, K; Paggiosi, MA; Peel, NF1
Ehlert, KM; Hernandez, CJ; Lin, I; Matheny, JB; Slyfield, CR; Tkachenko, EV; Tomlinson, RE; Wilson, DL1
Baas, J; Barckman, J; Bechtold, JE; Hermansen, LL; Søballe, K; Sørensen, M1
Hirai, K; Inoue, T; Kanehara, H; Nagatoya, K; Nishimoto, K; Okada, S; Shibahara, N; Takahashi, T; Ueda, H; Ueno, N; Yasuda, H1
Compston, J1
Kalam, A; Talegaonkar, S; Vohora, D1
Kobayashi, T; Matsumoto, M; Miyamoto, K; Miyamoto, T; Morita, M; Nakamura, M; Oike, T; Sato, Y; Tando, T; Watanabe, R1
Calignano, A; Corrado, B; Lama, A; Mattace Raso, G; Meli, R; Paciello, O; Pagano, TB; Pirozzi, C; Russo, S; Santoro, A1
Adami, S; Bianchi, G; Di Munno, O; Fiore, CE; Giannini, S; Minisola, S; Rossini, M; Sinigaglia, L1
Pepersack, T1
Stepan, JJ; Zikan, V1
Boekhoff, J; Herrmann, TR; Rack, T; Sehmisch, S; Seidlova-Wuttke, D; Stuermer, EK; Stuermer, KM; Tezval, H; Tezval, M; Wuttke, W1
Cegieła, U; Folwarczna, J; Kaczmarczyk-Sedlak, I; Nowińska, B; Pytlik, M; Sliwiński, L; Trzeciak, H; Trzeciak, HI1
Oshima, H; Tanaka, I1
Inaba, M; Shidara, K1
Ohnaka, K; Takayanagi, R1
Gorai, I; Hattori, S; Iwaoki, Y; Tanaka, Y1
Harris, ST; Mitchner, NA1
Iba, K; Takada, J; Yamashita, T; Yoshizaki, T2
Shimada, H; Takami, M1
Canpolat, S; Kumru, S; Seyran, AD; Tug, N; Yilmaz, B1
Gong, YX; Huang, L; Liu, JM; Lu, SY; Pang, XF; Wang, ZG; Xu, Y; Yan, MZ; Zhao, YJ1
Enokida, M; Hagino, H; Hayashi, I; Okano, T; Teshima, R1
Bhat, KM; Nampurath, GK; Potu, BK; Rao, MS1
Bauer, DC; Schousboe, JT1
Dwivedi, C; Khan, S; Parmar, V; Shirwaikar, A; Srinivasan, KK1
Eriguchi, M; Haruyama, N; Kitazono, T; Nakano, T; Tanaka, S; Taniguchi, M; Tsuruya, K; Yamada, S; Yoshida, H1
Celi, M; D'Erasmo, E; Letizia, C; Mazzuoli, GF; Minisola, S; Ragno, A1
Matsumoto, T1
Bryant, HU; Cole, HW; Hoover, J; Jee, WS; Ma, YL; Sato, M; Schmidt, A; Yao, W; Zeng, Q1
Calcagnile, F; Carlo Isaia, G; Cosentino, L; D'Amelio, P; Muratore, M; Quarta, E; Tamone, C; Tinelli, F1
Anderson, DW; Bhagwat, SS; Brady, H; Gayo-Fung, LM; Leisten, J; Lipps, SG; McKie, JA; O'Leary, E; Patnaik, N; Stein, B; Sutherland, MK1
Burde, MA; Cohen-Solal, ME; de Vernejoul, MC; Maudelonde, T; Rey, JM; Saintier, D1
Bonn, D1
Itabashi, A1
Ferrer-Barriendos, J; Gaines, K; Geusens, P; Melton, ME; Ribot, C; Sambrook, PN; Solimano, JA; Verbruggen, N1
Alenfeld, F; Boivin, G; Feyen, JH; Lakatos, P; Stepan, JJ1
Ammann, P; Baron, R; Bourrin, S; Brunner, F; Clément-Lacroix, P; Gaillard, M; Meyer, JM; Rizzoli, R1
Ohta, H3
Hamaya, E; Kobayashi, H1
Falbo, A; Lombardi, G; Manguso, F; Mastrantonio, P; Nunziata, V; Orio, F; Palomba, S; Russo, T; Tolino, A; Zullo, F1
Hosking, DJ; Pande, I1
Brixen, K; Mosekilde, L; Vestergaard, P1
Bashir, A; Cheung, J; Fogelman, I; Grigoriadis, AE; Hampson, G; Mak, YT; McGowan, NW; Sankaralingam, S1
Ellerbeck, EF; Jachna, CM; Rigler, SK; Shireman, TI; Whittle, J1
Altunyurt, S; Cakmak, A; Caliskan, S; Dogan, E; Guclu, S; Posaci, C1
Brown, SA; Rosen, CJ1
Armamento-Villareal, R; Brodt, MD; Caruso, PL; Civelli, M; Civitelli, R; Galbiati, E; Halstead, LR; Mueller, C; Napoli, N; Nawaz, A; Sheikh, S; Silva, MJ1
Matsuno, A; Okazaki, R; Okinaga, H1
Takada, J1
Narayana Murthy, PS; Sengupta, S; Sharma, S; Singh, MM1
Fassbender, WJ; Kurth, A; Stumpf, UC1
Asano, S; Kanematsu, M; Kikkawa, H; Kinoshita, M; Mitamura, M; Xiang, A1
Odvina, CV1
Jordan, VC1
Cremers, S; Garnero, P1
Järvinen, TL; Kannus, P; Sievänen, H1
Härkönen, PL; Hentunen, TA; Kangas, L; Michael, H; Väänänen, HK1
Barbuto, N; Cosman, F; Lindsay, R; Nieves, JW; Zion, M1
Mashiba, T1
Fournier, B; Hall, TJ; Nyugen, H; Schaueblin, M1
Bryant, HU; Evans, G; Magee, D; Sato, M; Turner, RT1
Bekele, A; Bendele, R; Bensch, WR; Black, LJ; Cullinan, GJ; Kauffman, RF; Magee, DE; Rowley, ER; Sato, M; Williams, DC1
Black, EC; Bryant, HU; Chandrasekhar, S; Frolik, CA; Magee, DE1
Raisz, LG1
Bryant, HU; Cho, S; Dodge, JA; Frolik, CA; Glasebrook, AL; Lugar, CW; Martin, MJ; Osborne, JJ; Phillips, DL; Sato, M; Short, LL; Spangle, LA; Yang, NN1
Draper, MW; Heaney, RP1
Bryant, HU; Dere, WH1
Zaidi, M1
Christiansen, C1
Chapman, B1
Kleerekoper, M1
Ito, M; Miyaura, C; Nozawa, S; Ohta, H; Onoe, Y; Suda, T1
Bénichou, O; Cohen-Solal, M; de Vernejoul, MC1
Bélanger, A; Labrie, C; Labrie, F; Martel, C; Picard, S; Richard, V1
Delmas, PD; Eastell, R; Garnero, P; Seibel, MJ; Stepan, J1
Atkinson, EJ; Doran, PM; Khosla, S; Riggs, BL1
Harper, K; Lips, P; Lu, Y; Oleksik, A; Ott, SM1

Reviews

25 review(s) available for raloxifene hydrochloride and Bone Loss, Osteoclastic

ArticleYear
Emerging therapeutic concepts for muscle and bone preservation/building.
    Bone, 2015, Volume: 80

    Topics: Anabolic Agents; Animals; Bone Density; Bone Remodeling; Bone Resorption; Denosumab; Diphosphonates; Fractures, Bone; Humans; Muscle, Skeletal; Osteoporosis; Raloxifene Hydrochloride

2015
[Treatment of osteoporosis in octogenarians].
    Revue medicale de Bruxelles, 2008, Volume: 29, Issue:4

    Topics: Aged, 80 and over; Attitude to Health; Bone Density Conservation Agents; Bone Resorption; Calcitonin; Diphosphonates; Fractures, Bone; Frail Elderly; Humans; Osteoporosis; Perception; Raloxifene Hydrochloride

2008
[Drug selection guide for osteoporosis determined by the clinical staging, pathophysiology and age].
    Nihon rinsho. Japanese journal of clinical medicine, 2009, Volume: 67, Issue:5

    Topics: Age Factors; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Bone Resorption; Calcium; Diphosphonates; Drug Therapy, Combination; Female; Hip Fractures; Humans; Osteoporosis; Raloxifene Hydrochloride; Risk; Vitamin D

2009
[Bone metabolic marker for osteoporosis].
    Nihon rinsho. Japanese journal of clinical medicine, 2009, Volume: 67, Issue:5

    Topics: Acid Phosphatase; Alkaline Phosphatase; Amino Acids; Biomarkers; Bone and Bones; Bone Density Conservation Agents; Bone Resorption; Collagen Type I; Diphosphonates; Female; Fractures, Bone; Humans; Isoenzymes; Osteoporosis; Peptides; Raloxifene Hydrochloride; Risk Assessment; Tartrate-Resistant Acid Phosphatase

2009
[Biochemical markers of bone turnover. New aspect. Effects of androgen and estrogen on biochemical markers of bone turnover].
    Clinical calcium, 2009, Volume: 19, Issue:8

    Topics: Androgens; Biomarkers; Bone and Bones; Bone Remodeling; Bone Resorption; Estrogen Replacement Therapy; Estrogens; Female; Humans; Male; Osteoporosis, Postmenopausal; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators

2009
Current and emerging therapies for osteoporosis.
    The Journal of family practice, 2009, Volume: 58, Issue:7 Suppl Os

    Topics: Bone and Bones; Bone Density Conservation Agents; Bone Resorption; Calcitonin; Diphosphonates; Drug Therapy, Combination; Estrogens; Humans; Osteoporosis; Raloxifene Hydrochloride; Teriparatide; Treatment Outcome

2009
[Effects of SERMs on bone health. The effects of raloxifene on bone quality evaluated by hip structure analysis].
    Clinical calcium, 2010, Volume: 20, Issue:3

    Topics: Bone Density; Bone Density Conservation Agents; Bone Resorption; Diphosphonates; Female; Femur; Humans; Osteogenesis; Osteoporosis, Postmenopausal; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Teriparatide

2010
[Effects of SERMs on bone health. SERM and metabolic markers of bone].
    Clinical calcium, 2010, Volume: 20, Issue:3

    Topics: Acid Phosphatase; Biomarkers; Bone and Bones; Bone Density Conservation Agents; Bone Remodeling; Bone Resorption; Clinical Trials as Topic; Diphosphonates; Humans; Isoenzymes; Osteoporosis; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tartrate-Resistant Acid Phosphatase

2010
Clinical use of bone turnover markers to monitor pharmacologic fracture prevention therapy.
    Current osteoporosis reports, 2012, Volume: 10, Issue:1

    Topics: Alendronate; Bone Density; Bone Density Conservation Agents; Bone Resorption; Clinical Trials as Topic; Diphosphonates; Humans; Imidazoles; Monitoring, Physiologic; Osteoporotic Fractures; Raloxifene Hydrochloride; Wound Healing; Zoledronic Acid

2012
[Osteoporosis].
    Ryumachi. [Rheumatism], 2002, Volume: 42, Issue:6

    Topics: Animals; Bone Resorption; Calcitriol; Clinical Trials as Topic; Diphosphonates; Humans; Osteoblasts; Osteoclasts; Osteogenesis; Osteoporosis; Parathyroid Hormone; Raloxifene Hydrochloride; Vitamin D

2002
[Raloxifene hydrochloride].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 2

    Topics: Arteriosclerosis; Bone Density; Bone Resorption; Breast Neoplasms; Cardiovascular Diseases; Cholesterol, LDL; Clinical Trials as Topic; Estrogen Antagonists; Estrogens; Female; Humans; Osteoporosis, Postmenopausal; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Spinal Fractures

2004
Mechanisms of action of antiresorptive therapies of postmenopausal osteoporosis.
    Endocrine regulations, 2003, Volume: 37, Issue:4

    Topics: Alendronate; Bone Density; Bone Remodeling; Bone Resorption; Calcitonin; Diphosphonates; Estrogen Replacement Therapy; Estrogens; Female; Humans; Osteoporosis, Postmenopausal; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators

2003
[Defining the role of raloxifene as a therapeutic agent for postmenopausal osteoporosis: focus on its pharmacological properties].
    Clinical calcium, 2004, Volume: 14, Issue:10

    Topics: Biomarkers; Bone and Bones; Bone Density; Bone Resorption; Female; Femoral Neck Fractures; Humans; Osteocalcin; Osteoporosis, Postmenopausal; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators; Spinal Fractures

2004
[Raloxifene hydrochloride (Evista Tablet 60 mg) for postmenopausal osteoporosis: mode of action and clinical efficacy].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2005, Volume: 125, Issue:1

    Topics: Animals; Bone and Bones; Bone Density; Bone Remodeling; Bone Resorption; Breast Neoplasms; Controlled Clinical Trials as Topic; Coronary Disease; Female; Fractures, Bone; Humans; Osteoporosis, Postmenopausal; Raloxifene Hydrochloride; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Stroke; Transcription Factors

2005
Oral antiresorptive therapy.
    Current rheumatology reports, 2005, Volume: 7, Issue:1

    Topics: Administration, Oral; Alendronate; Anabolic Agents; Bone Resorption; Diphosphonates; Drug Therapy, Combination; Etidronic Acid; Fractures, Bone; Glucocorticoids; Humans; Ibandronic Acid; Osteoporosis; Raloxifene Hydrochloride; Risedronic Acid; Selective Estrogen Receptor Modulators; Teriparatide

2005
[Treatment of osteoporosis with antiresorptive drugs].
    Ugeskrift for laeger, 2005, Feb-21, Volume: 167, Issue:8

    Topics: Bone Density; Bone Resorption; Calcitonin; Calcium; Cholecalciferol; Diphosphonates; Estradiol; Estrogens, Conjugated (USP); Female; Humans; Male; Osteoporosis; Osteoporosis, Postmenopausal; Progesterone; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Vitamin D

2005
[SERMs: an update for clinicians].
    Clinical calcium, 2005, Volume: 15, Issue:4

    Topics: Animals; Bone and Bones; Bone Resorption; Drug Design; Evidence-Based Medicine; Fractures, Spontaneous; Humans; Osteoporosis; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators

2005
A rational approach to evidence gaps in the management of osteoporosis.
    The American journal of medicine, 2005, Volume: 118, Issue:11

    Topics: Age Factors; Aged; Animals; Bone Density; Bone Density Conservation Agents; Bone Diseases, Metabolic; Bone Resorption; Case Management; Cohort Studies; Diphosphonates; Drug Therapy, Combination; Estrogens; Evidence-Based Medicine; Female; Follow-Up Studies; Fractures, Spontaneous; Health Surveys; Hip Fractures; Humans; Incidence; Middle Aged; Osteoporosis, Postmenopausal; Parathyroid Hormone; Raloxifene Hydrochloride; Rats; Risk Assessment; Spinal Fractures; Time Factors

2005
[Application of anti-resorptive drugs for the treatment of osteoporosis].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64, Issue:2

    Topics: Aged; Alendronate; Bone Resorption; Diphosphonates; Etidronic Acid; Female; Fractures, Bone; Humans; Osteoporosis; Raloxifene Hydrochloride; Risedronic Acid

2006
[Effect of raloxifene as a SERM on bone metabolism].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 4

    Topics: Bone and Bones; Bone Density; Bone Resorption; Female; Fractures, Bone; Humans; Osteoporosis; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators

2006
Osteoporosis: how should it be treated?
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2006, Volume: 54, Issue:3

    Topics: Bone Density; Bone Resorption; Calcitonin; Diphosphonates; Drug Therapy, Combination; Estrogens; Humans; Osteoporosis; Parathyroid Hormone; Peptide Fragments; Raloxifene Hydrochloride

2006
Biochemical markers of bone turnover in the clinical development of drugs for osteoporosis and metastatic bone disease: potential uses and pitfalls.
    Drugs, 2006, Volume: 66, Issue:16

    Topics: Adrenal Cortex Hormones; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Biomarkers; Bone Density; Bone Diseases, Metabolic; Bone Neoplasms; Bone Remodeling; Bone Resorption; Calcitonin; Cathepsin K; Cathepsins; Collagen Type I; Denosumab; Diphosphonates; Drug Administration Schedule; Drug Design; Female; Humans; Organometallic Compounds; Osteitis Deformans; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Parathyroid Hormone; Raloxifene Hydrochloride; RANK Ligand; Thiophenes

2006
[Assessment of bone quality. Bone quality and osteoporosis treatment].
    Clinical calcium, 2008, Volume: 18, Issue:3

    Topics: Aging; Bone and Bones; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Bone Resorption; Calcification, Physiologic; Diphosphonates; Female; Humans; Osteoporosis, Postmenopausal; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators

2008
Selective estrogen receptor modulators: an alternative to hormone replacement therapy.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1998, Volume: 217, Issue:1

    Topics: Bone Resorption; Cholesterol; Estrogen Antagonists; Estrogen Replacement Therapy; Estrogens; Female; Humans; Osteoporosis, Postmenopausal; Piperidines; Raloxifene Hydrochloride; Receptors, Estrogen; Tamoxifen; Uterus

1998
The use of biochemical markers of bone turnover in osteoporosis. Committee of Scientific Advisors of the International Osteoporosis Foundation.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2000, Volume: 11 Suppl 6

    Topics: Biomarkers; Bone Density; Bone Regeneration; Bone Remodeling; Bone Resorption; Diphosphonates; Estrogens; Female; Fractures, Spontaneous; Humans; Osteoporosis; Osteoporosis, Postmenopausal; Periodicity; Prognosis; Raloxifene Hydrochloride; Risk Assessment; Terminology as Topic

2000

Trials

12 trial(s) available for raloxifene hydrochloride and Bone Loss, Osteoclastic

ArticleYear
Raloxifene Prevents Early Periprosthetic Bone Loss for Postmenopausal Women after Uncemented Total Hip Arthroplasty: A Randomized Placebo-Controlled Clinical Trial.
    Orthopaedic surgery, 2020, Volume: 12, Issue:4

    Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Bone Density Conservation Agents; Bone Resorption; Disability Evaluation; Double-Blind Method; Female; Humans; Middle Aged; Osteoporosis; Postmenopause; Postoperative Complications; Prospective Studies; Quality of Life; Raloxifene Hydrochloride

2020
Adherence to raloxifene therapy: assessment methods and relationship with efficacy.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2013, Volume: 24, Issue:11

    Topics: Absorptiometry, Photon; Aged; Aged, 80 and over; Biomarkers; Bone Density; Bone Density Conservation Agents; Bone Resorption; Collagen Type I; Drug Administration Schedule; Drug Monitoring; Drug Packaging; Electrical Equipment and Supplies; England; Female; Humans; Medication Adherence; Middle Aged; Osteoporosis, Postmenopausal; Peptides; Raloxifene Hydrochloride; Tablets

2013
Marked reduction of bone turnover by alendronate attenuates the acute response of bone resorption marker to endogenous parathyroid hormone.
    Bone, 2009, Volume: 44, Issue:4

    Topics: Aged; Aged, 80 and over; Alendronate; Area Under Curve; Biomarkers; Bone Density Conservation Agents; Bone Remodeling; Bone Resorption; Chelating Agents; Collagen Type I; Edetic Acid; Etidronic Acid; Female; Humans; Hypocalcemia; Middle Aged; Osteoporosis, Postmenopausal; Parathyroid Hormone; Peptides; Raloxifene Hydrochloride; Risedronic Acid

2009
Assessment of adherence to treatment of postmenopausal osteoporosis with raloxifene and/or alfacalcidol in postmenopausal Japanese women.
    Journal of bone and mineral metabolism, 2010, Volume: 28, Issue:2

    Topics: Aged; Aged, 80 and over; Biomarkers; Bone and Bones; Bone Density; Bone Density Conservation Agents; Bone Diseases, Metabolic; Bone Resorption; Drug Therapy, Combination; Female; Humans; Hydroxycholecalciferols; Japan; Medication Adherence; Middle Aged; Osteogenesis; Osteoporosis, Postmenopausal; Patient Dropouts; Raloxifene Hydrochloride; Statistics as Topic; Surveys and Questionnaires; Time Factors

2010
Effect of raloxifene and clodronate on bone density in postmenopausal osteoporotic women.
    International journal of tissue reactions, 2003, Volume: 25, Issue:2

    Topics: Absorptiometry, Photon; Aged; Biomarkers; Bone Density; Bone Remodeling; Bone Resorption; Cholecalciferol; Clodronic Acid; Female; Humans; Middle Aged; Osteoporosis, Postmenopausal; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators

2003
Alendronate produces greater effects than raloxifene on bone density and bone turnover in postmenopausal women with low bone density: results of EFFECT (Efficacy of FOSAMAX versus EVISTA Comparison Trial) International.
    Journal of internal medicine, 2004, Volume: 255, Issue:4

    Topics: Alendronate; Alkaline Phosphatase; Biomarkers; Bone Density; Bone Resorption; Double-Blind Method; Female; Hip; Humans; Lumbar Vertebrae; Middle Aged; Osteoporosis, Postmenopausal; Raloxifene Hydrochloride; Time Factors; Treatment Outcome

2004
BsmI vitamin D receptor genotypes influence the efficacy of antiresorptive treatments in postmenopausal osteoporotic women. A 1-year multicenter, randomized and controlled trial.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2005, Volume: 16, Issue:8

    Topics: Administration, Oral; Aged; Alendronate; Bone Density; Bone Density Conservation Agents; Bone Resorption; Drug Combinations; Drug Therapy, Combination; Estrogens, Conjugated (USP); Female; Genotype; Hormone Replacement Therapy; Humans; Medroxyprogesterone Acetate; Middle Aged; Osteoporosis, Postmenopausal; Prospective Studies; Raloxifene Hydrochloride; Receptors, Calcitriol; Selective Estrogen Receptor Modulators; Treatment Outcome

2005
Changes in RANKL/OPG/RANK gene expression in peripheral mononuclear cells following treatment with estrogen or raloxifene.
    Steroids, 2005, Dec-01, Volume: 70, Issue:13

    Topics: Aged; Bone Density; Bone Resorption; Carrier Proteins; Collagen; Collagen Type I; Estrogens; Female; Gene Expression Regulation; Glycoproteins; Hormone Replacement Therapy; Humans; Leukocytes, Mononuclear; Longitudinal Studies; Membrane Glycoproteins; Middle Aged; Osteoporosis; Osteoprotegerin; Peptides; Postmenopause; Raloxifene Hydrochloride; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; RNA, Messenger; Selective Estrogen Receptor Modulators

2005
Effect of prior and ongoing raloxifene therapy on response to PTH and maintenance of BMD after PTH therapy.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2008, Volume: 19, Issue:4

    Topics: Aged; Bone Density; Bone Density Conservation Agents; Bone Resorption; Female; Follow-Up Studies; Humans; Middle Aged; Osteoporosis, Postmenopausal; Parathyroid Hormone; Raloxifene Hydrochloride; Treatment Outcome

2008
Raloxifene and estrogen: comparative bone-remodeling kinetics.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:10

    Topics: Bone Remodeling; Bone Resorption; Calcium; Creatinine; Estrogen Antagonists; Estrogens; Female; Humans; Hydroxyproline; Middle Aged; Piperidines; Postmenopause; Raloxifene Hydrochloride

1997
Effects of raloxifene, a selective estrogen receptor modulator, on bone turnover markers and serum sex steroid and lipid levels in elderly men.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2001, Volume: 16, Issue:11

    Topics: Aged; Biomarkers; Bone Remodeling; Bone Resorption; Collagen; Collagen Type I; Estradiol; Follicle Stimulating Hormone; Gonadal Steroid Hormones; Humans; Lipids; Luteinizing Hormone; Male; Middle Aged; Osteoporosis; Parathyroid Hormone; Peptides; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators

2001
Bone histomorphometric and biochemical marker results of a 2-year placebo-controlled trial of raloxifene in postmenopausal women.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2002, Volume: 17, Issue:2

    Topics: Aged; Biopsy; Bone Density; Bone Resorption; Double-Blind Method; Estrogen Antagonists; Female; Humans; Middle Aged; Osteoporosis, Postmenopausal; Postmenopause; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Spinal Fractures

2002

Other Studies

49 other study(ies) available for raloxifene hydrochloride and Bone Loss, Osteoclastic

ArticleYear
Improving Combination Osteoporosis Therapy in a Preclinical Model of Heightened Osteoanabolism.
    Endocrinology, 2017, 09-01, Volume: 158, Issue:9

    Topics: Animals; Bone and Bones; Bone Resorption; Diphosphonates; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Imidazoles; Mice; Mice, Knockout; Nuclear Matrix-Associated Proteins; Osteoporosis; Parathyroid Hormone; Raloxifene Hydrochloride; Transcription Factors; Zoledronic Acid

2017
Combined administration on You-Gui Yin and low-dose Raloxifene partially attenuates the bone loss in ovariectomized mice through the proliferation and osteogenic differentiation of bone marrow stromal cells.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2019, Volume: 53

    Topics: Animals; Bone Density; Bone Density Conservation Agents; Bone Resorption; Cell Differentiation; Cell Proliferation; Disease Models, Animal; Drug Synergism; Drugs, Chinese Herbal; Female; Mesenchymal Stem Cells; Mice, Inbred C57BL; Osteogenesis; Osteoporosis; Ovariectomy; Raloxifene Hydrochloride; Tibia

2019
Anti-resorptive agents reduce the size of resorption cavities: a three-dimensional dynamic bone histomorphometry study.
    Bone, 2013, Volume: 57, Issue:1

    Topics: Animals; Bone Density Conservation Agents; Bone Remodeling; Bone Resorption; Etidronic Acid; Female; Ovariectomy; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Risedronic Acid

2013
Incorporation of raloxifene-impregnated allograft around orthopedic titanium implants impairs early fixation but improves new bone formation.
    Acta orthopaedica, 2015, Volume: 86, Issue:1

    Topics: Allografts; Animals; Bone Density Conservation Agents; Bone Resorption; Bone Transplantation; Dogs; Osseointegration; Osteogenesis; Prostheses and Implants; Raloxifene Hydrochloride; Tibia; Titanium

2015
Effects of raloxifene on bone metabolism in postmenopausal women on chronic hemodialysis.
    Clinical and experimental nephrology, 2015, Volume: 19, Issue:5

    Topics: Acid Phosphatase; Aged; Alkaline Phosphatase; Biomarkers; Bone and Bones; Bone Density Conservation Agents; Bone Resorption; Female; Humans; Isoenzymes; Kidney Failure, Chronic; Middle Aged; Osteoporosis, Postmenopausal; Osteoporotic Fractures; Parathyroid Hormone; Postmenopause; Prospective Studies; Raloxifene Hydrochloride; Renal Dialysis; Tartrate-Resistant Acid Phosphatase

2015
Effects of raloxifene against letrozole-induced bone loss in chemically-induced model of menopause in mice.
    Molecular and cellular endocrinology, 2017, 01-15, Volume: 440

    Topics: Adaptor Proteins, Signal Transducing; Animals; Biomarkers; Bone Remodeling; Bone Resorption; Cyclohexenes; Female; Femur; Glycoproteins; Intercellular Signaling Peptides and Proteins; Letrozole; Lumbar Vertebrae; Menopause; Mice; Nitriles; Raloxifene Hydrochloride; Triazoles; Vinyl Compounds

2017
Selective estrogen receptor modulators and the vitamin D analogue eldecalcitol block bone loss in male osteoporosis.
    Biochemical and biophysical research communications, 2017, Jan-22, Volume: 482, Issue:4

    Topics: Animals; Bone and Bones; Bone Density; Bone Density Conservation Agents; Bone Diseases, Metabolic; Bone Resorption; Indoles; Male; Mice; Mice, Inbred C57BL; Orchiectomy; Osteoporosis; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen; Testosterone; Vitamin D

2017
Extracorporeal shock waves alone or combined with raloxifene promote bone formation and suppress resorption in ovariectomized rats.
    PloS one, 2017, Volume: 12, Issue:2

    Topics: Adiponectin; Animals; Biomarkers; Bone and Bones; Bone Density Conservation Agents; Bone Resorption; Disease Models, Animal; Female; High-Energy Shock Waves; Osteogenesis; Osteoporosis; Ovariectomy; PPAR gamma; Raloxifene Hydrochloride; Rats; Transcription, Genetic

2017
Vitamin D status and response to treatment in post-menopausal osteoporosis.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2009, Volume: 20, Issue:2

    Topics: Activities of Daily Living; Aged; Alendronate; Biomarkers; Bone Density; Bone Density Conservation Agents; Bone Resorption; Calcium; Confounding Factors, Epidemiologic; Dietary Supplements; Etidronic Acid; Female; Fractures, Bone; Humans; Incidence; Logistic Models; Middle Aged; Odds Ratio; Osteoporosis, Postmenopausal; Raloxifene Hydrochloride; Retrospective Studies; Risedronic Acid; Risk; Treatment Outcome; Vitamin D; Vitamin D Deficiency

2009
Effect of testosterone, raloxifene and estrogen replacement on the microstructure and biomechanics of metaphyseal osteoporotic bones in orchiectomized male rats.
    World journal of urology, 2009, Volume: 27, Issue:4

    Topics: Administration, Oral; Animals; Biomechanical Phenomena; Bone and Bones; Bone Density; Bone Resorption; Disease Models, Animal; Estrogens; Hormone Replacement Therapy; Male; Orchiectomy; Osteoporosis; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Testosterone

2009
A comparative study of the effects of genistein, estradiol and raloxifene on the murine skeletal system.
    Acta biochimica Polonica, 2009, Volume: 56, Issue:2

    Topics: Animals; Body Weight; Bone and Bones; Bone Density; Bone Marrow Cells; Bone Resorption; Calcification, Physiologic; Calcium; Cell Count; Cells, Cultured; Disease Models, Animal; Drug Combinations; Estradiol; Estriol; Female; Gene Expression; Genistein; Humans; Mice; Mice, Inbred BALB C; Organ Size; Osteoblasts; Osteoclasts; Osteoporosis, Postmenopausal; Ovariectomy; Phytoestrogens; Raloxifene Hydrochloride; Rats; Rats, Wistar; RNA, Messenger; Selective Estrogen Receptor Modulators; Thymus Gland; Uterus

2009
Effects of raloxifene and estradiol on bone turnover parameters in intact and ovariectomized rats.
    Journal of physiology and biochemistry, 2010, Volume: 66, Issue:1

    Topics: Alkaline Phosphatase; Animals; Bone Density; Bone Density Conservation Agents; Bone Resorption; Estradiol; Female; Osteocalcin; Ovariectomy; Parathyroid Hormone; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley

2010
Raloxifene inhibits bone loss and improves bone strength through an Opg-independent mechanism.
    Endocrine, 2010, Volume: 37, Issue:1

    Topics: Animals; Bone and Bones; Bone Density; Bone Density Conservation Agents; Bone Resorption; Cell Count; Elastic Modulus; Female; Femur; Gene Expression Regulation; Lumbar Vertebrae; Mechanical Phenomena; Mice; Mice, Knockout; Osteoclasts; Osteoprotegerin; Raloxifene Hydrochloride; Random Allocation; RANK Ligand; RNA, Messenger

2010
Effect of raloxifene on arthritis and bone mineral density in rats with collagen-induced arthritis.
    Calcified tissue international, 2011, Volume: 88, Issue:2

    Topics: Animals; Arthritis; Arthritis, Experimental; Bone Density; Bone Density Conservation Agents; Bone Resorption; Disease Models, Animal; Female; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley

2011
Effect of Cissus quadrangularis Linn on the development of osteopenia induced by ovariectomy in rats.
    La Clinica terapeutica, 2011, Volume: 162, Issue:4

    Topics: Acid Phosphatase; Alkaline Phosphatase; Alkanes; Animals; Biomarkers; Bone Diseases, Metabolic; Bone Resorption; Calcium; Cissus; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Femur; Humans; Hydroxyproline; Isoenzymes; Osteoporosis, Postmenopausal; Ovariectomy; Phytotherapy; Plant Extracts; Raloxifene Hydrochloride; Random Allocation; Rats; Rats, Wistar; Tartrate-Resistant Acid Phosphatase

2011
Correlation between a bone resorption marker and structural geometry of the proximal femur in osteoporotic women treated with raloxifene.
    Journal of orthopaedic surgery (Hong Kong), 2012, Volume: 20, Issue:2

    Topics: Absorptiometry, Photon; Aged; Biomarkers; Bone Density; Bone Density Conservation Agents; Bone Resorption; Collagen Type I; Female; Femur; Humans; Middle Aged; Osteoporosis, Postmenopausal; Peptides; Raloxifene Hydrochloride

2012
Methanol extract of dried exudate of Commiphora mukul prevents bone resorption in ovariectomized rats.
    Pharmaceutical biology, 2012, Volume: 50, Issue:10

    Topics: Acid Phosphatase; Animals; Bone Density; Bone Density Conservation Agents; Bone Resorption; Calcium; Cholesterol; Commiphora; Dose-Response Relationship, Drug; Female; Isoenzymes; Methanol; Ovariectomy; Plant Extracts; Raloxifene Hydrochloride; Random Allocation; Rats; Rats, Wistar; Tartrate-Resistant Acid Phosphatase

2012
The clinical utility of serum tartrate-resistant acid phosphatase 5b in the assessment of bone resorption in patients on peritoneal dialysis.
    Clinical endocrinology, 2013, Volume: 78, Issue:6

    Topics: Acid Phosphatase; Acute Kidney Injury; Adult; Aged; Alkaline Phosphatase; Biomarkers; Bone and Bones; Bone Resorption; Cinacalcet; Collagen Type I; Cross-Sectional Studies; Female; Humans; Hydroxycholecalciferols; Isoenzymes; Male; Middle Aged; Naphthalenes; Parathyroid Hormone; Peptides; Peritoneal Dialysis; Raloxifene Hydrochloride; Regression Analysis; Tartrate-Resistant Acid Phosphatase

2013
ACOG Practice Bulletin: Clinical Management Guidelines for Obstetrician-Gynecologists: Number 39, October 2002. Selective estrogen receptor modulators.
    Obstetrics and gynecology, 2002, Volume: 100, Issue:4

    Topics: Bone Resorption; Breast Neoplasms; Cardiovascular Diseases; Endometrium; Female; Genitalia, Female; Hot Flashes; Humans; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen; Thromboembolism

2002
[Effects of the combined raloxifene-sodium fluoride therapy on bone mass and bone turnover in women with postmenopausal osteoporosis].
    Minerva medica, 2002, Volume: 93, Issue:6

    Topics: Analysis of Variance; Bone and Bones; Bone Density; Bone Remodeling; Bone Resorption; Case-Control Studies; Drug Therapy, Combination; Female; Humans; Middle Aged; Osteoporosis, Postmenopausal; Raloxifene Hydrochloride; Sodium Fluoride

2002
New bone formation with teriparatide [human parathyroid hormone-(1-34)] is not retarded by long-term pretreatment with alendronate, estrogen, or raloxifene in ovariectomized rats.
    Endocrinology, 2003, Volume: 144, Issue:5

    Topics: Alendronate; Animals; Biomechanical Phenomena; Bone Density; Bone Resorption; Drug Administration Schedule; Ethinyl Estradiol; Female; Femur; Osteogenesis; Ovariectomy; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Spine; Tensile Strength; Teriparatide; Tibia; Time Factors

2003
Effects of SP500263, a novel selective estrogen receptor modulator, on bone, uterus, and serum cholesterol in the ovariectomized rat.
    Calcified tissue international, 2003, Volume: 72, Issue:6

    Topics: Administration, Oral; Animals; Body Weight; Bone Density; Bone Resorption; Cholesterol; Coumarins; Dose-Response Relationship, Drug; Female; Femur; Organ Size; Ovariectomy; Piperidines; Radiography; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Triglycerides; Uterus

2003
17beta-estradiol downregulates beta3-integrin expression in differentiating and mature human osteoclasts.
    Journal of cellular physiology, 2004, Volume: 198, Issue:2

    Topics: Blotting, Western; Bone and Bones; Bone Resorption; Cell Differentiation; Down-Regulation; Estradiol; Estrogen Antagonists; Female; Fluorescent Antibody Technique; Humans; Integrin beta3; Organ Culture Techniques; Osteoclasts; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Raloxifene Hydrochloride; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors

2004
New ways with old bones. Osteoporosis researchers look for drugs to replace hormone replacement therapy.
    Lancet (London, England), 2004, Mar-06, Volume: 363, Issue:9411

    Topics: Antioxidants; Bone Resorption; Carrier Proteins; Contraindications; Female; Hormone Replacement Therapy; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Isoflavones; Leptin; Membrane Glycoproteins; Osteoporosis; Phytoestrogens; Plant Preparations; Raloxifene Hydrochloride; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Selective Estrogen Receptor Modulators; Teriparatide

2004
A new selective estrogen receptor modulator HMR-3339 fully corrects bone alterations induced by ovariectomy in adult rats.
    Bone, 2004, Volume: 35, Issue:1

    Topics: Animals; Bone and Bones; Bone Density; Bone Resorption; Compressive Strength; Estradiol; Female; Osteocalcin; Ovariectomy; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Selective Estrogen Receptor Modulators

2004
Differing patterns of antiresorptive pharmacotherapy in nursing facility residents and community dwellers.
    Journal of the American Geriatrics Society, 2005, Volume: 53, Issue:8

    Topics: Aged; Aged, 80 and over; Analysis of Variance; Bone Resorption; Calcitonin; Cross-Sectional Studies; Demography; Diphosphonates; Female; Hormone Replacement Therapy; Humans; Nursing Homes; Osteoporosis; Raloxifene Hydrochloride; Residence Characteristics

2005
Raloxifene increases serum leptin levels in postmenopausal women: a prospective study.
    American journal of obstetrics and gynecology, 2005, Volume: 193, Issue:2

    Topics: Adult; Aged; Alkaline Phosphatase; Bone and Bones; Bone Resorption; Collagen; Collagen Type I; Female; Humans; Insulin-Like Growth Factor I; Leptin; Middle Aged; Osteocalcin; Peptides; Postmenopause; Prospective Studies; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators

2005
A new selective estrogen receptor modulator, CHF 4227.01, preserves bone mass and microarchitecture in ovariectomized rats.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2005, Volume: 20, Issue:12

    Topics: Absorptiometry, Photon; Amino Acids; Animals; Benzopyrans; Biomechanical Phenomena; Blood; Body Composition; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Cholesterol; Compressive Strength; Estrogen Receptor Modulators; Ethinyl Estradiol; Female; Femur; Femur Neck; Lumbar Vertebrae; Organ Size; Osteoclasts; Osteogenesis; Ovariectomy; Piperidines; Pyrrolidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Tetrahydronaphthalenes; Tibia; Tomography, X-Ray Computed; Triglycerides; Uterus; Weight-Bearing

2005
High risk of osteopenia and bone derangement in postsurgical patients with craniopharyngiomas, pituitary adenomas and other parasellar lesions.
    Endocrine journal, 2005, Volume: 52, Issue:6

    Topics: Adolescent; Adult; Aged; Bone Density; Bone Diseases, Metabolic; Bone Resorption; Child; Collagen; Collagen Type I; Craniopharyngioma; Diphosphonates; Estrogens; Female; Follicle Stimulating Hormone; Gonadotropins; Humans; Hydrocortisone; Hypopituitarism; Luteinizing Hormone; Male; Middle Aged; Peptides; Pituitary Neoplasms; Raloxifene Hydrochloride; Risk Factors; Testosterone; Thyroxine

2005
Effect of ormeloxifene on ovariectomy-induced bone resorption, osteoclast differentiation and apoptosis and TGF beta-3 expression.
    The Journal of steroid biochemistry and molecular biology, 2006, Volume: 100, Issue:4-5

    Topics: Animals; Apoptosis; Benzopyrans; Bone Density; Bone Marrow Cells; Bone Resorption; Calcium; Cell Differentiation; Cells, Cultured; Female; Lumbar Vertebrae; Mice; Mice, Inbred BALB C; Organ Size; Osteoclasts; Ovariectomy; Phosphorus; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Stem Cells; Transforming Growth Factor beta; Transforming Growth Factor beta3; Uterus

2006
[The successful development of bisphosphonates in the therapy of osteoporosis].
    Medizinische Klinik (Munich, Germany : 1983), 2006, Volume: 101 Suppl 1

    Topics: Administration, Oral; Bone Density; Bone Density Conservation Agents; Bone Diseases, Metabolic; Bone Resorption; Diphosphonates; Estrogen Antagonists; Female; Humans; Male; Middle Aged; Osteoporosis; Osteoporosis, Postmenopausal; Primary Prevention; Raloxifene Hydrochloride; Risk Reduction Behavior

2006
Analysis of change patterns of microcomputed tomography 3-dimensional bone parameters as a high-throughput tool to evaluate antiosteoporotic effects of agents at an early stage of ovariectomy-induced osteoporosis in mice.
    Investigative radiology, 2006, Volume: 41, Issue:9

    Topics: Animals; Bone Density Conservation Agents; Bone Resorption; Disease Models, Animal; Early Diagnosis; Estradiol; Female; Femur; Imaging, Three-Dimensional; Mice; Osteogenesis; Osteoporosis; Ovariectomy; Parathyroid Hormone; Peptide Fragments; Raloxifene Hydrochloride; Rolipram; Tomography, X-Ray Computed

2006
A STAR is born.
    Oncology (Williston Park, N.Y.), 2006, Volume: 20, Issue:9

    Topics: Bone Density Conservation Agents; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Drug Therapy, Combination; Female; Humans; Raloxifene Hydrochloride; Tamoxifen

2006
Bone quality: an empty term.
    PLoS medicine, 2007, Volume: 4, Issue:3

    Topics: Bone and Bones; Bone Density; Bone Resorption; Diphosphonates; Fractures, Bone; Humans; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators

2007
Differential effects of selective oestrogen receptor modulators (SERMs) tamoxifen, ospemifene and raloxifene on human osteoclasts in vitro.
    British journal of pharmacology, 2007, Volume: 151, Issue:3

    Topics: Animals; Apoptosis; Bone Resorption; Cattle; Cell Differentiation; Cell Line, Tumor; Cells, Cultured; Coculture Techniques; Dexamethasone; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Fulvestrant; Humans; Lipopolysaccharide Receptors; Macrophage Colony-Stimulating Factor; Monocytes; Osteoclasts; Osteoprotegerin; Raloxifene Hydrochloride; RANK Ligand; Selective Estrogen Receptor Modulators; Tamoxifen; Time Factors; Tumor Necrosis Factor-alpha

2007
The bone-specific estrogen centchroman inhibits osteoclastic bone resorption in vitro.
    Biochemical and biophysical research communications, 1995, Nov-13, Volume: 216, Issue:2

    Topics: Animals; Animals, Newborn; Bone Resorption; Calcitonin; Cells, Cultured; Centchroman; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Humans; Kinetics; Molecular Structure; Osteoclasts; Piperidines; Raloxifene Hydrochloride; Rats; Structure-Activity Relationship

1995
The effects of raloxifene on tibia histomorphometry in ovariectomized rats.
    Endocrinology, 1994, Volume: 134, Issue:5

    Topics: Aging; Animals; Body Weight; Bone and Bones; Bone Development; Bone Resorption; Cell Count; Cholesterol; Female; Organ Size; Osteoclasts; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Tibia; Uterus

1994
Raloxifene (LY139481 HCI) prevents bone loss and reduces serum cholesterol without causing uterine hypertrophy in ovariectomized rats.
    The Journal of clinical investigation, 1994, Volume: 93, Issue:1

    Topics: Administration, Oral; Alkaline Phosphatase; Animals; Body Weight; Bone Density; Bone Resorption; Calcium; Cholesterol; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Estrogen Antagonists; Ethinyl Estradiol; Female; Hypertrophy; Ovariectomy; Phosphorus; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Triglycerides; Uterus

1994
Time-dependent changes in biochemical bone markers and serum cholesterol in ovariectomized rats: effects of raloxifene HCl, tamoxifen, estrogen, and alendronate.
    Bone, 1996, Volume: 18, Issue:6

    Topics: Alendronate; Amino Acids; Animals; Biomarkers; Body Weight; Bone Resorption; Cholesterol; Disease Models, Animal; Estrogen Antagonists; Estrogen Replacement Therapy; Female; Humans; Organ Size; Osteoporosis, Postmenopausal; Ovariectomy; Piperidines; Radioimmunoassay; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Tamoxifen; Uterus

1996
Estrogen and bone: new pieces to the puzzle.
    Nature medicine, 1996, Volume: 2, Issue:10

    Topics: Animals; Bone Resorption; Estradiol; Estrogen Antagonists; Estrogens; Female; Gene Expression Regulation; Humans; Mice; Osteoblasts; Osteoclasts; Osteoporosis, Postmenopausal; Piperidines; Raloxifene Hydrochloride; Tamoxifen; Transforming Growth Factor beta

1996
Evaluation of the major metabolites of raloxifene as modulators of tissue selectivity.
    The Journal of steroid biochemistry and molecular biology, 1997, Volume: 61, Issue:1-2

    Topics: Adenocarcinoma; Animals; Bone Resorption; Breast Neoplasms; Cell Division; Cells, Cultured; Estradiol; Estrogen Antagonists; Female; Glucuronates; Humans; Interleukin-6; Organ Specificity; Osteoclasts; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Tissue Distribution; Transforming Growth Factor beta; Tumor Cells, Cultured

1997
Biological basis of anti-resorptive therapies for osteoporosis.
    Aging (Milan, Italy), 1998, Volume: 10, Issue:2

    Topics: Aged; Alendronate; Bone Resorption; Calcitonin; Estrogen Replacement Therapy; Female; Humans; Middle Aged; Osteoporosis; Osteoporosis, Postmenopausal; Piperidines; Raloxifene Hydrochloride

1998
Sex steroid analogs.
    Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 1999, Volume: 9 Suppl 2

    Topics: Animals; Bone Resorption; Breast Neoplasms; Estrogen Antagonists; Female; Gonadal Steroid Hormones; Hormones; Humans; Norpregnenes; Osteoporosis, Postmenopausal; Pyrrolidines; Raloxifene Hydrochloride; Receptors, Estrogen; Risk; Tamoxifen

1999
Biochemical bone markers.
    CAP today, 1999, Volume: 13, Issue:5

    Topics: Alendronate; Biomarkers; Bone Remodeling; Bone Resorption; Diphosphonates; Estrogen Antagonists; Female; Hormone Replacement Therapy; Humans; Lipids; Osteoporosis, Postmenopausal; Piperidines; Raloxifene Hydrochloride

1999
Frequency of bone densitometry for osteoporosis?
    Postgraduate medicine, 1999, Volume: 106, Issue:6

    Topics: Absorptiometry, Photon; Alendronate; Biomarkers; Bone Density; Bone Resorption; Calcitonin; Estrogen Replacement Therapy; Female; Follow-Up Studies; Humans; Osteoporosis, Postmenopausal; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Time Factors

1999
Comparative effects of estrogen and raloxifene on B lymphopoiesis and bone loss induced by sex steroid deficiency in mice.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2000, Volume: 15, Issue:3

    Topics: Androgens; Animals; B-Lymphocytes; Bone Marrow; Bone Remodeling; Bone Resorption; Estradiol; Estrogen Replacement Therapy; Estrogens; Female; Hematopoiesis; Humans; Lymphocyte Count; Male; Mice; Orchiectomy; Organ Size; Osteoporosis; Osteoporosis, Postmenopausal; Ovariectomy; Raloxifene Hydrochloride; Uterus

2000
[Physiopathology of bone loss and pharmacologic approach of selective estrogen receptor modulators].
    Joint bone spine, 2000, Volume: 67 Suppl 1

    Topics: Animals; Bone Resorption; Cytokines; Estrogens; Female; Humans; Interleukin-6; Raloxifene Hydrochloride; Receptors, Estrogen; Selective Estrogen Receptor Modulators

2000
Drugs for prevention and treatment of postmenopausal osteoporosis.
    The Medical letter on drugs and therapeutics, 2000, Oct-16, Volume: 42, Issue:1090

    Topics: Absorptiometry, Photon; Aged; Alendronate; Bone Density; Bone Resorption; Breast Neoplasms; Calcitonin; Calcium; Calcium Channel Blockers; Clinical Trials as Topic; Densitometry; Dose-Response Relationship, Drug; Estrogens; Etidronic Acid; Female; Humans; Middle Aged; Osteoporosis, Postmenopausal; Raloxifene Hydrochloride; Risedronic Acid; Risk Factors; Vitamin D

2000
Prevention of bone loss by EM-800 and raloxifene in the ovariectomized rat.
    The Journal of steroid biochemistry and molecular biology, 2000, Volume: 74, Issue:1-2

    Topics: Administration, Oral; Amino Acids; Animals; Benzopyrans; Bone Density; Bone Diseases, Metabolic; Bone Resorption; Cholesterol; Disease Models, Animal; Epithelial Cells; Estradiol; Estrogens; Female; Femur; Lumbar Vertebrae; Organ Size; Ovariectomy; Postmenopause; Propionates; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Tibia; Time Factors; Triglycerides; Uterus

2000