raloxifene hydrochloride has been researched along with Alzheimer Disease in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 10 (58.82) | 29.6817 |
| 2010's | 4 (23.53) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Bu, X; Chen, D; Feng, Y; Liu, Z; Qin, W; Shao, W; Su, H; Wang, Y; Zhou, B | 1 |
| Bochar, DA; Deng, X; Dexheimer, T; Hovde, S; Kuo, MH; Kwok, R; Liu, M; Sui, D | 1 |
| Yang, ZD; Yu, J; Zhang, Q | 1 |
| Ala, T; Bernstein, AL; Farlow, MR; Henderson, VW; Rosen, AC; Sainani, KL; Stephenson, BS | 1 |
| Hajjo, R; Roth, BL; Setola, V; Tropsha, A | 1 |
| Trivedi, MA; Zec, RF | 1 |
| Brinton, RD; Chen, S; O'Neill, K | 1 |
| Lütjohann, D; Mijatovic, V; Netelenbos, JC; Pinsdorf, U; van der Mooren, MJ; Vogelvang, TE; von Bergmann, K | 1 |
| Cummings, JL | 1 |
| Blackwell, T; Cummings, SR; Ensrud, K; Grady, D; Henderson, VW; Krueger, K; Sarkar, S; Yaffe, K | 1 |
| Kurachi, H; Murata, Y; Ohmichi, M; Tasaka, K | 1 |
| Bryant, HU; Cole, HW; Glinn, MA; Ni, B; Ostrowski, NL; Paul, SM; Su, Y; Wu, X | 1 |
| Birkhäuser, MH | 1 |
| Bryant, M; Clark, L; Garces, A; Rhodin, J; Thomas, T | 1 |
| Tiitinen, A; Välimäki, MJ | 1 |
| Friedrich, MJ | 1 |
| Emons, G; Westphalen, S | 1 |
4 review(s) available for raloxifene hydrochloride and Alzheimer Disease
| Article | Year |
|---|---|
Effects of raloxifene on cognition, mental health, sleep and sexual function in menopausal women: a systematic review of randomized controlled trials.
Topics: Alzheimer Disease; Cognition; Cognition Disorders; Female; Humans; Memory; Menopause; Mental Health; Raloxifene Hydrochloride; Reproductive Health; Selective Estrogen Receptor Modulators; Sleep | 2013 |
The effects of estrogen replacement therapy on neuropsychological functioning in postmenopausal women with and without dementia: a critical and theoretical review.
Topics: Aging; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Brain; Cognition; Dementia; Estrogen Replacement Therapy; Female; Humans; Memory; Neuropsychological Tests; Postmenopause; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators | 2002 |
Molecular mechanism of action of selective estrogen receptor modulator in target tissues.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Blood Vessels; Brain; Cell Division; Endothelial Cells; Female; Humans; Male; Mammary Glands, Human; Muscle, Smooth, Vascular; Organ Specificity; Phosphorylation; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Telomerase | 2005 |
[Indications for hormone replacement therapy].
Topics: Aged; Alzheimer Disease; Anabolic Agents; Breast Neoplasms; Cardiovascular Diseases; Contraindications; Endometrial Neoplasms; Estrogen Replacement Therapy; Estrogens; Female; Humans; Middle Aged; Norpregnenes; Osteoporosis, Postmenopausal; Postmenopause; Progestins; Raloxifene Hydrochloride; Risk; Selective Estrogen Receptor Modulators; Thrombosis | 2000 |
3 trial(s) available for raloxifene hydrochloride and Alzheimer Disease
| Article | Year |
|---|---|
Raloxifene for women with Alzheimer disease: A randomized controlled pilot trial.
Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Cholinesterase Inhibitors; Cognition; Double-Blind Method; Female; Humans; Pilot Projects; Raloxifene Hydrochloride; Treatment Outcome | 2015 |
Effect of raloxifene and hormone therapy on serum markers of brain and whole-body cholesterol metabolism in postmenopausal women.
Topics: Alzheimer Disease; Biomarkers; Brain; Cholesterol; Double-Blind Method; Estrogen Replacement Therapy; Estrogens, Conjugated (USP); Female; Humans; Hydroxycholesterols; Medroxyprogesterone Acetate; Middle Aged; Postmenopause; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Treatment Outcome | 2005 |
Effect of raloxifene on prevention of dementia and cognitive impairment in older women: the Multiple Outcomes of Raloxifene Evaluation (MORE) randomized trial.
Topics: Aged; Alzheimer Disease; Cognition Disorders; Comorbidity; Dementia; Female; Geriatric Assessment; Humans; Osteoporosis, Postmenopausal; Placebos; Psychiatric Status Rating Scales; Raloxifene Hydrochloride; Risk Assessment; Selective Estrogen Receptor Modulators; Severity of Illness Index; Spinal Fractures; Treatment Outcome | 2005 |
10 other study(ies) available for raloxifene hydrochloride and Alzheimer Disease
| Article | Year |
|---|---|
Raloxifene alleviates amyloid-β-induced cytotoxicity in HT22 neuronal cells via inhibiting oligomeric and fibrillar species formation.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Line; Cell Survival; Gene Expression; Hydrophobic and Hydrophilic Interactions; Mice; Microglia; Neurons; Neuroprotective Agents; Peptide Fragments; Protein Aggregates; Protein Aggregation, Pathological; Protein Domains; Raloxifene Hydrochloride; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2019 |
Hyperphosphorylated tau aggregation and cytotoxicity modulators screen identified prescription drugs linked to Alzheimer's disease and cognitive functions.
Topics: Alzheimer Disease; Apomorphine; Benzodiazepines; Cognition; Drug Discovery; Drug Evaluation, Preclinical; Humans; Phosphorylation; Prescription Drugs; Protein Aggregates; Raloxifene Hydrochloride; Risk Factors; tau Proteins | 2020 |
Chemocentric informatics approach to drug discovery: identification and experimental validation of selective estrogen receptor modulators as ligands of 5-hydroxytryptamine-6 receptors and as potential cognition enhancers.
Topics: Alzheimer Disease; Cell Line, Tumor; Cloning, Molecular; Cognition; Drug Discovery; Drug Evaluation, Preclinical; Genomics; Humans; Informatics; Ligands; Nootropic Agents; Quantitative Structure-Activity Relationship; Raloxifene Hydrochloride; Receptors, Serotonin; Reproducibility of Results; Selective Estrogen Receptor Modulators; Serotonin Antagonists; User-Computer Interface | 2012 |
Impact of the selective estrogen receptor modulator, raloxifene, on neuronal survival and outgrowth following toxic insults associated with aging and Alzheimer's disease.
Topics: Aging; Alzheimer Disease; Animals; Biomarkers; Cell Division; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Memory; Neurons; Neuroprotective Agents; Neurotoxins; Oxidants; Raloxifene Hydrochloride; Rats; Selective Estrogen Receptor Modulators | 2004 |
Searching for methods to detect, prevent, and treat Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic; Cognition Disorders; Donepezil; Female; Humans; Indans; Magnetic Resonance Spectroscopy; Occipital Lobe; Piperidines; Predictive Value of Tests; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Treatment Outcome | 2005 |
Raloxifene and estradiol benzoate both fully restore hippocampal choline acetyltransferase activity in ovariectomized rats.
Topics: Alzheimer Disease; Animals; Choline O-Acetyltransferase; Dose-Response Relationship, Drug; Estradiol; Female; Hippocampus; Ovariectomy; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators | 1999 |
Estrogen and raloxifene activities on amyloid-beta-induced inflammatory reaction.
Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Peptides; Animals; Estrogen Antagonists; Estrogens; Female; Humans; Inflammation; Male; Menopause; Ovariectomy; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Sex Factors | 2001 |
[Antiestrogens--benefits of estrogens without their disadvantages?].
Topics: Alzheimer Disease; Bone Density; Breast Neoplasms; Cholesterol; Estrogen Receptor Modulators; Estrogen Replacement Therapy; Estrogens; Female; Finland; Humans; Raloxifene Hydrochloride; Receptors, Estrogen; Selective Estrogen Receptor Modulators | 1998 |
Teasing out effects of estrogen on the brain.
Topics: Alzheimer Disease; Animals; Brain; Cognition; Estrogen Receptor alpha; Estrogens; Hippocampus; Humans; Raloxifene Hydrochloride; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Stroke | 2002 |
[Hormone replacement therapy in peri- and postmenopause. Routine use is not indicated].
Topics: Alzheimer Disease; Breast Neoplasms; Cardiovascular Diseases; Clinical Trials as Topic; Endometrial Neoplasms; Estrogen Replacement Therapy; Female; Hormone Replacement Therapy; Humans; Middle Aged; Osteoporosis, Postmenopausal; Ovarian Neoplasms; Primary Prevention; Progestins; Raloxifene Hydrochloride; Risk Factors; Selective Estrogen Receptor Modulators; Thrombosis; Time Factors | 2002 |