Page last updated: 2024-08-23

raloxifene hydrochloride and Aging

raloxifene hydrochloride has been researched along with Aging in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (7.41)18.2507
2000's18 (66.67)29.6817
2010's7 (25.93)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Almeida, RP; Chaves-Neto, AH; Dornelles, RCM; Ervolino, E; Fernandes, F; Louzada, MJQ; Morais, SRL; Perez-Ueno, MJ; Stringhetta-Garcia, CT1
Chaves-Neto, AH; Dornelles, RC; Ervolino, E; Louzada, MJ; Nakamune, AC; Rossi, AC; Santos, LF; Singulani, MP; Stringhetta-Garcia, CT1
Lovre, D; Mauvais-Jarvis, F; Xu, B1
Ohta, H1
Verhaar, HJ1
Sharpe, DT; Stevenson, S; Thornton, MJ1
Azcoitia, I; Barreto, G; Carrero, P; Diz-Chaves, Y; Garcia-Segura, LM; Pernía, O; Santos-Galindo, M1
Ichikawa, S; Sumino, H1
Miyakoshi, N1
Chen, LF; Du, XL; Ma, HS; Ma, YX; Shi, JD; Yang, R; Yang, ZP; Zhang, J; Zhou, Y; Zhu, Y1
Dantas, AP; Heras, M; Hermenegildo, C; Novella, S1
Trivedi, MA; Zec, RF1
Hengemihle, J; Ingram, DK; Lei, DL; Long, JM; Manaye, KF; Mouton, PR; O'Neill, J1
Brinton, RD; Chen, S; O'Neill, K1
Barkhof, F; Duschek, EJ; Goekoop, R; Knol, DL; Netelenbos, C; Rombouts, SA; Scheltens, P1
Mijatovic, V; van der Mooren, MJ; Vogelvang, TE1
Duschek, EJ; Gooren, LJ; Netelenbos, C1
Bleiberg, I; Kaye, AM; Ofer, M; Somjen, D1
Au, CL; Fung, KP; Huang, Y; Laher, I; Tsang, SY; Vanhoutte, PM; Wong, CM; Yao, X1
Mashiba, T1
Bryant, HU; Kim, J; Sato, M; Short, LL; Slemenda, CW1
Bryant, HU; Evans, G; Magee, D; Sato, M; Turner, RT1
Black, D; Cox, D; Cummings, S; Duong, T; Lips, P; Nickelsen, T; Oleksik, A1
Aguilar, E; Gaytán, F; González, LC; Pinilla, L; Tena-Sempere, M1
Butterworth, M; Greaves, P; Green, A; Parrott, E; White, IN1
Ammann, P; Bonjour, JP; Bourrin, S; Rizzoli, R1
Clarkson, TB; Mikkola, TS1

Reviews

8 review(s) available for raloxifene hydrochloride and Aging

ArticleYear
The effect of selective estrogen receptor modulators on type 2 diabetes onset in women: Basic and clinical insights.
    Journal of diabetes and its complications, 2017, Volume: 31, Issue:4

    Topics: Aging; Animals; Antineoplastic Agents, Hormonal; Bone Density Conservation Agents; Diabetes Mellitus, Type 2; Energy Metabolism; Female; Humans; Indoles; Insulin Resistance; Models, Biological; Obesity; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen

2017
[Role of estrogen and selective estrogen receptor modulators in anti-aging].
    Clinical calcium, 2008, Volume: 18, Issue:7

    Topics: Aging; Animals; Bone and Bones; Bone Density; Breast Neoplasms; Estrogen Replacement Therapy; Estrogens; Female; Fractures, Bone; Humans; Osteoporosis; Perimenopause; Raloxifene Hydrochloride; Risk; Selective Estrogen Receptor Modulators

2008
[Effects of SERMs on bone health. SERM actions other than on the bones. With special reference to the actions of SERM on the skin and vascular elasticity].
    Clinical calcium, 2010, Volume: 20, Issue:3

    Topics: Aging; Arteries; Bone Density Conservation Agents; Elasticity; Estrogens; Female; Humans; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Skin; Skin Physiological Phenomena

2010
[Musculoskeletal rehabilitation and bone. Influence of medicines and hormones on musculoskeletal rehabilitation].
    Clinical calcium, 2010, Volume: 20, Issue:4

    Topics: Accidental Falls; Aging; Bone Density Conservation Agents; Diphosphonates; Estrogen Replacement Therapy; Exercise; Female; Gonadal Steroid Hormones; Humans; Musculoskeletal Diseases; Musculoskeletal System; Osteoporosis, Postmenopausal; Raloxifene Hydrochloride; Sarcopenia; Vitamin D

2010
The effects of estrogen replacement therapy on neuropsychological functioning in postmenopausal women with and without dementia: a critical and theoretical review.
    Neuropsychology review, 2002, Volume: 12, Issue:2

    Topics: Aging; Alzheimer Disease; Apolipoprotein E4; Apolipoproteins E; Brain; Cognition; Dementia; Estrogen Replacement Therapy; Female; Humans; Memory; Neuropsychological Tests; Postmenopause; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators

2002
Hormone replacement therapy, selective estrogen receptor modulators, and tissue-specific compounds: cardiovascular effects and clinical implications.
    Treatments in endocrinology, 2004, Volume: 3, Issue:2

    Topics: Aging; Animals; Arteriosclerosis; Cardiovascular Diseases; Cardiovascular System; Estrogen Replacement Therapy; Female; Humans; Menopause; Middle Aged; Norpregnenes; Postmenopause; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Selective Estrogen Receptor Modulators; Tamoxifen

2004
[Assessment of bone quality. Bone quality and osteoporosis treatment].
    Clinical calcium, 2008, Volume: 18, Issue:3

    Topics: Aging; Bone and Bones; Bone Density; Bone Density Conservation Agents; Bone Remodeling; Bone Resorption; Calcification, Physiologic; Diphosphonates; Female; Humans; Osteoporosis, Postmenopausal; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators

2008
Estrogen replacement therapy, atherosclerosis, and vascular function.
    Cardiovascular research, 2002, Feb-15, Volume: 53, Issue:3

    Topics: Aged; Aging; Animals; Coronary Artery Disease; Endothelium, Vascular; Estrogen Replacement Therapy; Estrogens, Non-Steroidal; Female; Humans; Inflammation; Isoflavones; Lipids; Macaca; Male; Middle Aged; Models, Animal; Phytoestrogens; Plant Preparations; Progestins; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators

2002

Trials

3 trial(s) available for raloxifene hydrochloride and Aging

ArticleYear
Raloxifene exposure enhances brain activation during memory performance in healthy elderly males; its possible relevance to behavior.
    NeuroImage, 2005, Volume: 25, Issue:1

    Topics: Aged; Aging; Arousal; Attention; Brain Mapping; Cerebral Cortex; Dominance, Cerebral; Double-Blind Method; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Memory, Short-Term; Mental Recall; Middle Aged; Pattern Recognition, Visual; Problem Solving; Raloxifene Hydrochloride; Reference Values; Retention, Psychology; Selective Estrogen Receptor Modulators; Statistics as Topic

2005
Comparison of effects of the rise in serum testosterone by raloxifene and oral testosterone on serum insulin-like growth factor-1 and insulin-like growth factor binding protein-3.
    Maturitas, 2005, Jul-16, Volume: 51, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Aged; Aging; Double-Blind Method; Estrogen Antagonists; Female; Humans; Insulin-Like Growth Factor Binding Protein 3; Insulin-Like Growth Factor I; Male; Middle Aged; Multivariate Analysis; Raloxifene Hydrochloride; Testosterone; Transsexualism

2005
A global study of vitamin D status and parathyroid function in postmenopausal women with osteoporosis: baseline data from the multiple outcomes of raloxifene evaluation clinical trial.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:3

    Topics: Absorptiometry, Photon; Adult; Aged; Aged, 80 and over; Aging; Alkaline Phosphatase; Bone Density; Calcifediol; Calcium; Cholecalciferol; Female; Humans; Immunoradiometric Assay; Middle Aged; Nutritional Status; Osteoporosis, Postmenopausal; Parathyroid Hormone; Postmenopause; Radioimmunoassay; Raloxifene Hydrochloride; Seasons

2001

Other Studies

16 other study(ies) available for raloxifene hydrochloride and Aging

ArticleYear
Effects of strength training and raloxifene on femoral neck metabolism and microarchitecture of aging female Wistar rats.
    Scientific reports, 2017, 10-31, Volume: 7, Issue:1

    Topics: Aging; Animals; Bone Density; Bone Density Conservation Agents; Combined Modality Therapy; Female; Femur Neck; Osteoblasts; Osteoclasts; Osteoporosis; Phosphates; Raloxifene Hydrochloride; Random Allocation; Rats, Wistar; Resistance Training; Tartrate-Resistant Acid Phosphatase

2017
The effects of strength training and raloxifene on bone health in aging ovariectomized rats.
    Bone, 2016, Volume: 85

    Topics: Aging; Animals; Biomarkers; Body Weight; Bone and Bones; Bone Density; Bone Remodeling; Estradiol; Female; Femur; Imaging, Three-Dimensional; Organ Size; Ovariectomy; Raloxifene Hydrochloride; Rats, Wistar; Resistance Training; Uterus

2016
[Treatment of osteoporosis in the elderly: what is the evidence?].
    Tijdschrift voor gerontologie en geriatrie, 2008, Volume: 39, Issue:5

    Topics: Age Factors; Aged; Aged, 80 and over; Aging; Alendronate; Bone Density; Bone Density Conservation Agents; Etidronic Acid; Evidence-Based Medicine; Female; Fractures, Bone; Humans; Male; Osteoporosis; Osteoporosis, Postmenopausal; Raloxifene Hydrochloride; Risedronic Acid; Teriparatide; Treatment Outcome

2008
Effects of oestrogen agonists on human dermal fibroblasts in an in vitro wounding assay.
    Experimental dermatology, 2009, Volume: 18, Issue:11

    Topics: Aging; Cell Movement; DNA; Estrogen Receptor alpha; Estrogens; Female; Fibroblasts; Humans; In Vitro Techniques; Middle Aged; Models, Biological; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Skin; Tamoxifen; Wound Healing

2009
Selective estrogen receptor modulators decrease reactive astrogliosis in the injured brain: effects of aging and prolonged depletion of ovarian hormones.
    Endocrinology, 2009, Volume: 150, Issue:11

    Topics: Aging; Animals; Astrocytes; Brain; Brain Injuries; Estradiol; Estrogens; Female; Ovariectomy; Raloxifene Hydrochloride; Rats; Rats, Wistar; Selective Estrogen Receptor Modulators; Tamoxifen; Vimentin

2009
Antagonism of estrogen-mediated cell proliferation by raloxifene in prevention of ageing-related prostatic hyperplasia.
    Asian journal of andrology, 2010, Volume: 12, Issue:5

    Topics: 5-alpha Reductase Inhibitors; Aging; Animals; Cell Line; Cell Proliferation; Estrogen Antagonists; Finasteride; Humans; Male; Models, Animal; Proliferating Cell Nuclear Antigen; Prostate; Prostatic Hyperplasia; Raloxifene Hydrochloride; Rats; Rats, Wistar; Selective Estrogen Receptor Modulators; Tamoxifen

2010
Effects of estrogen on vascular inflammation: a matter of timing.
    Arteriosclerosis, thrombosis, and vascular biology, 2012, Volume: 32, Issue:8

    Topics: Adult; Aged; Aging; Biomarkers; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Humans; Interleukin-6; Menopause; Middle Aged; Raloxifene Hydrochloride; Time Factors; Vasculitis

2012
Effects of estrogen and raloxifene on neuroglia number and morphology in the hippocampus of aged female mice.
    Neuroscience, 2003, Volume: 121, Issue:3

    Topics: Aging; Animals; Cell Count; Estrogen Antagonists; Estrogens; Female; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; Macrophage-1 Antigen; Mice; Mice, Inbred C57BL; Neuroglia; Ovariectomy; Raloxifene Hydrochloride; Stereotaxic Techniques

2003
Impact of the selective estrogen receptor modulator, raloxifene, on neuronal survival and outgrowth following toxic insults associated with aging and Alzheimer's disease.
    Experimental neurology, 2004, Volume: 185, Issue:1

    Topics: Aging; Alzheimer Disease; Animals; Biomarkers; Cell Division; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Memory; Neurons; Neuroprotective Agents; Neurotoxins; Oxidants; Raloxifene Hydrochloride; Rats; Selective Estrogen Receptor Modulators

2004
The role of non-calcemic analogs of vitamin D in differentiation of cultured rat bone marrow into osteoblast-like cells: age and sex differences.
    Journal of endocrinological investigation, 2005, Volume: 28, Issue:10

    Topics: Aging; Alkaline Phosphatase; Animals; Bone Marrow Cells; Calcitriol; Cell Differentiation; Cells, Cultured; Creatine Kinase; Dexamethasone; Dihydrotestosterone; Estradiol; Female; Male; Orchiectomy; Osteoblasts; Ovariectomy; Raloxifene Hydrochloride; Rats; Rats, Inbred WKY; Sex Characteristics

2005
Raloxifene prevents endothelial dysfunction in aging ovariectomized female rats.
    Vascular pharmacology, 2006, Volume: 44, Issue:5

    Topics: Acetylcholine; Aging; Animals; Aorta, Thoracic; Bone Density Conservation Agents; Calcium Chloride; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; Nitric Oxide; Nitric Oxide Synthase Type III; Ovariectomy; Phenylephrine; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2006
Longitudinal and cross-sectional analysis of raloxifene effects on tibiae from ovariectomized aged rats.
    The Journal of pharmacology and experimental therapeutics, 1995, Volume: 272, Issue:3

    Topics: Aging; Animals; Bone Density; Ethinyl Estradiol; Female; Lipids; Organ Size; Osteoporosis; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Tibia; Tomography, X-Ray Computed; Uterus

1995
The effects of raloxifene on tibia histomorphometry in ovariectomized rats.
    Endocrinology, 1994, Volume: 134, Issue:5

    Topics: Aging; Animals; Body Weight; Bone and Bones; Bone Development; Bone Resorption; Cell Count; Cholesterol; Female; Organ Size; Osteoclasts; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Tibia; Uterus

1994
Oestrogenic effects of neonatal administration of raloxifene on hypothalamic-pituitary-gonadal axis in male and female rats.
    Reproduction (Cambridge, England), 2001, Volume: 121, Issue:6

    Topics: Aging; Animals; Animals, Newborn; Anovulation; Epithelial Cells; Female; Follicle Stimulating Hormone; Gonads; Hyperprolactinemia; Hypothalamus; Infertility, Female; Luteinizing Hormone; Male; Pituitary Gland; Raloxifene Hydrochloride; Rats; Rats, Wistar; Selective Estrogen Receptor Modulators; Vagina; Vaginal Smears; Weight Loss

2001
Adenomyosis--a result of disordered stromal differentiation.
    The American journal of pathology, 2001, Volume: 159, Issue:2

    Topics: Administration, Oral; Aging; Animals; Animals, Newborn; Body Weight; Calcium-Binding Proteins; Cell Differentiation; Endometriosis; Estradiol; Female; Gene Expression Regulation; Growth Inhibitors; Insulin-Like Growth Factor II; Intercellular Signaling Peptides and Proteins; Membrane Proteins; Mice; Myometrium; Nerve Growth Factor; Oligonucleotide Array Sequence Analysis; Organ Size; Raloxifene Hydrochloride; Repressor Proteins; Selective Estrogen Receptor Modulators; Stromal Cells; Tamoxifen; Toremifene; Uterus

2001
Recovery of proximal tibia bone mineral density and strength, but not cancellous bone architecture, after long-term bisphosphonate or selective estrogen receptor modulator therapy in aged rats.
    Bone, 2002, Volume: 30, Issue:1

    Topics: Aging; Animals; Biomechanical Phenomena; Bone Density; Bone Remodeling; Clomiphene; Diphosphonates; Female; Organ Size; Ovariectomy; Pamidronate; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Selective Estrogen Receptor Modulators; Tibia

2002