Page last updated: 2024-08-23

raloxifene hydrochloride and Adenocarcinoma

raloxifene hydrochloride has been researched along with Adenocarcinoma in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (21.74)18.2507
2000's11 (47.83)29.6817
2010's6 (26.09)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Bruns, CJ; Camaj, P; Hartmann, L; Hering, NA; Kreis, ME; Lee, LD; Liu, V; Müller, MH; Pozios, I; Seel, NN; Seeliger, H1
Brewer, M; Bryant, T; Janakiram, NB; Lightfoot, S; Mohammed, A; Rao, CV; Steele, VE; Zhang, Y1
Alexi, X; Alexis, MN; Fokialakis, N; Haroutounian, SA; Kasiotis, KM; Lambrinidis, G; Meligova, AK; Mikros, E1
Atkins, JN; Bevers, TB; Cecchini, RS; Costantino, JP; Cronin, WM; Fehrenbacher, L; Ford, LG; Ganz, PA; James, J; Jordan, VC; Margolese, RG; McCaskill-Stevens, W; Pajon, ER; Reis, SE; Robidoux, A; Runowicz, CD; Vogel, VG; Wade, JL; Wickerham, DL; Wolmark, N1
Brown, PH; Hortobagyi, GN1
Ravdin, PM1
Cuzick, J1
Ansar, A; Hussey, DJ; Sukocheva, OA; Watson, DI; Wee, C1
Burd, CJ; Feng, Y; Khan, SA; Singleton, DW1
Amezcua, CA; Boostanfar, R; Felix, JC; Roy, S; Stanczyk, FZ; Tourgeman, DE1
Cornella, JL; Hibner, M; Lefler, SR; Loftus, JC; Magrina, JF; Pizarro, AR1
Haczynski, J; Jarzabek, K; Knapp, P; Koda, M; Sulkowski, S; Wolczynski, S1
Chen, Y; Imaida, K; Kakehi, Y; Matsuda, Y; Saoo, K; Takeuchi, H; Yamakawa, K; Yokohira, M; Zeng, Y1
Brown, PH; Uray, IP1
Best, KL; Counts, DF; Goode, RL; Hoover, DM; Jones, CD; Merriman, RL; Neubauer, BL; Sarosdy, MF; Shaar, CJ; Tanzer, LR1
Adrian, MD; Bryant, HU; Cho, S; Cole, HW; Finley, DR; Glasebrook, AL; Godfrey, AG; Grese, TA; Jones, CD; Lugar, CW; Magee, DE; Martin, MJ; Matsumoto, K; Pennington, LD; Phillips, DL; Rowley, ER; Short, LL; Winter, MA1
Belanger, A; Gauthier, S; Labrie, C; Labrie, F; Merand, Y; Poirier, D; Sanchez, R; Simard, J; Singh, SM1
Bryant, HU; Cho, S; Dodge, JA; Frolik, CA; Glasebrook, AL; Lugar, CW; Martin, MJ; Osborne, JJ; Phillips, DL; Sato, M; Short, LL; Spangle, LA; Yang, NN1
Boersma, CJ; Dijkema, R; Mosselman, S; Mulder, WR; Olijve, W; van den Wijngaard, A; van Zoelen, EJ1
Anchim, T; Dabrowska, M; Dziecioł, J; Swiatecka, J; Wołczyński, S1
Mosca, L1
Chen, B; Dardes, RC; Jordan, VC; Osipo, C; Pearce, ST; Schafer, JM1
Bennett, JA; Bowser, SS; Bradley, L; Dickerman, HW; Gierthy, JF; Lincoln, DW; Roth, KE1

Reviews

2 review(s) available for raloxifene hydrochloride and Adenocarcinoma

ArticleYear
Prevention of breast cancer: current state of the science and future opportunities.
    Expert opinion on investigational drugs, 2006, Volume: 15, Issue:12

    Topics: Adenocarcinoma; Adult; Aged; Animals; Antineoplastic Agents, Hormonal; Aromatase Inhibitors; Breast Neoplasms; Clinical Trials as Topic; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Drug Evaluation, Preclinical; Drug Therapy, Combination; Estrogen Receptor Modulators; Estrogens; Female; Forecasting; Humans; Leuprolide; Mammary Neoplasms, Experimental; Mice; Middle Aged; Ovariectomy; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Rats; Retinoids; Selective Estrogen Receptor Modulators; Tamoxifen

2006
Rationale and overview of the Raloxifene Use for the Heart (RUTH) trial.
    Annals of the New York Academy of Sciences, 2001, Volume: 949

    Topics: Adenocarcinoma; Breast Neoplasms; Cardiovascular Diseases; Estrogen Replacement Therapy; Female; Humans; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators

2001

Trials

2 trial(s) available for raloxifene hydrochloride and Adenocarcinoma

ArticleYear
Update of the National Surgical Adjuvant Breast and Bowel Project Study of Tamoxifen and Raloxifene (STAR) P-2 Trial: Preventing breast cancer.
    Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:6

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Breast Neoplasms; Cataract; Double-Blind Method; Drug Utilization; Endometrial Neoplasms; Estrogens; Female; Follow-Up Studies; Fractures, Spontaneous; Humans; Incidence; Middle Aged; Myocardial Ischemia; Neoplasm Invasiveness; Neoplasms, Hormone-Dependent; Osteoporosis, Postmenopausal; Raloxifene Hydrochloride; Risk; Selective Estrogen Receptor Modulators; Tamoxifen; Thromboembolism; Uterus

2010
Rationale and overview of the Raloxifene Use for the Heart (RUTH) trial.
    Annals of the New York Academy of Sciences, 2001, Volume: 949

    Topics: Adenocarcinoma; Breast Neoplasms; Cardiovascular Diseases; Estrogen Replacement Therapy; Female; Humans; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators

2001

Other Studies

20 other study(ies) available for raloxifene hydrochloride and Adenocarcinoma

ArticleYear
Raloxifene inhibits pancreatic adenocarcinoma growth by interfering with ERβ and IL-6/gp130/STAT3 signaling.
    Cellular oncology (Dordrecht), 2021, Volume: 44, Issue:1

    Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Cell Proliferation; Cytokine Receptor gp130; Estrogen Receptor beta; Humans; Interleukin-6; Male; Mice, Nude; Neoplasm Metastasis; Pancreatic Neoplasms; Raloxifene Hydrochloride; Signal Transduction; STAT3 Transcription Factor; Time Factors; Xenograft Model Antitumor Assays

2021
Chemopreventive efficacy of raloxifene, bexarotene, and their combination on the progression of chemically induced colon adenomas to adenocarcinomas in rats.
    Cancer prevention research (Philadelphia, Pa.), 2013, Volume: 6, Issue:12

    Topics: Adenocarcinoma; Adenoma; Adult; Aged; Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Bexarotene; Biomarkers, Tumor; Blotting, Western; Colonic Neoplasms; Drug Therapy, Combination; Estrogen Antagonists; Estrogen Receptor beta; Female; Humans; Immunoenzyme Techniques; Male; Middle Aged; Neoplasm Grading; Raloxifene Hydrochloride; Rats; Rats, Inbred F344; Real-Time Polymerase Chain Reaction; Retinoid X Receptors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrahydronaphthalenes; Tissue Array Analysis; Tumor Cells, Cultured

2013
Differential estrogen receptor subtype modulators: assessment of estrogen receptor subtype-binding selectivity and transcription-regulating properties of new cycloalkyl pyrazoles.
    The Journal of steroid biochemistry and molecular biology, 2009, Volume: 117, Issue:4-5

    Topics: Adenocarcinoma; Binding Sites; Cell Line, Tumor; Estradiol; Humans; Male; Models, Molecular; Prostatic Neoplasms; Pyrazoles; Raloxifene Hydrochloride; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Transcription, Genetic

2009
Two good choices to prevent breast cancer: great taste, less filling.
    Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:6

    Topics: Adenocarcinoma; Breast Neoplasms; Drug Utilization; Endometrial Neoplasms; Estrogens; Female; Follow-Up Studies; Humans; Incidence; Meta-Analysis as Topic; Multicenter Studies as Topic; Neoplasms, Hormone-Dependent; Osteoporosis, Postmenopausal; Practice Patterns, Physicians'; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Risk Assessment; Risk Reduction Behavior; Selective Estrogen Receptor Modulators; Tamoxifen; Uterus

2010
The lack, need, and opportunities for decision-making and informational tools to educate primary-care physicians and women about breast cancer chemoprevention.
    Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:6

    Topics: Adenocarcinoma; Breast Neoplasms; Decision Support Techniques; Drug Utilization; Estrogens; Female; Humans; Incidence; Internet; Multicenter Studies as Topic; Neoplasms, Hormone-Dependent; Patient Education as Topic; Physicians, Family; Practice Patterns, Physicians'; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Risk Assessment; Risk Reduction Behavior; Selective Estrogen Receptor Modulators; Tamoxifen

2010
Long-term follow-up in cancer prevention trials (It ain't over 'til it's over).
    Cancer prevention research (Philadelphia, Pa.), 2010, Volume: 3, Issue:6

    Topics: Adenocarcinoma; Breast Neoplasms; Double-Blind Method; Drug Utilization; Endometrial Neoplasms; Estrogens; Female; Follow-Up Studies; Human Papillomavirus Recombinant Vaccine Quadrivalent, Types 6, 11, 16, 18; Humans; Incidence; Multicenter Studies as Topic; Neoplasms, Hormone-Dependent; Papillomavirus Vaccines; Raloxifene Hydrochloride; Randomized Controlled Trials as Topic; Risk Assessment; Risk Reduction Behavior; Sample Size; Selective Estrogen Receptor Modulators; Tamoxifen; Uterine Cervical Neoplasms

2010
Effect of estrogen on growth and apoptosis in esophageal adenocarcinoma cells.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2013, Volume: 26, Issue:6

    Topics: Adenocarcinoma; Apoptosis; Barrett Esophagus; Cadherins; Cell Count; Cell Culture Techniques; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Esophageal Neoplasms; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens; Female; Humans; Ki-67 Antigen; Male; Raloxifene Hydrochloride; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen

2013
Nongenomic activity and subsequent c-fos induction by estrogen receptor ligands are not sufficient to promote deoxyribonucleic acid synthesis in human endometrial adenocarcinoma cells.
    Endocrinology, 2003, Volume: 144, Issue:1

    Topics: Adenocarcinoma; DNA; Endometrial Neoplasms; Enzyme Activation; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Gene Expression; Humans; Luciferases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mutation; Proto-Oncogene Mas; Proto-Oncogene Proteins c-fos; Raloxifene Hydrochloride; Receptors, Estrogen; Recombinant Fusion Proteins; Response Elements; Tamoxifen; Transfection; Tumor Cells, Cultured

2003
Growth effects of raloxifene, estradiol, medroxy-progesterone acetate, and progesterone on human endometrial adenocarcinoma cells.
    Fertility and sterility, 2003, Volume: 79, Issue:1

    Topics: Adenocarcinoma; Cell Division; Endometrial Neoplasms; Estradiol; Estrogen Replacement Therapy; Female; Humans; Medroxyprogesterone Acetate; Progesterone; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tumor Cells, Cultured

2003
Effects of raloxifene hydrochloride on endometrial cancer cells in vitro.
    Gynecologic oncology, 2004, Volume: 93, Issue:3

    Topics: Adenocarcinoma; Cell Division; Cell Line, Tumor; Endometrial Neoplasms; Estradiol; Female; Humans; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators

2004
Differential effects of raloxifene and tamoxifen on the expression of estrogen receptors and antigen Ki-67 in human endometrial adenocarcinoma cell line.
    Oncology reports, 2004, Volume: 12, Issue:3

    Topics: Adenocarcinoma; Antineoplastic Agents, Hormonal; Cell Division; Cell Line, Tumor; Endometrial Neoplasms; Estrogen Antagonists; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Ki-67 Antigen; Raloxifene Hydrochloride; Receptors, Estrogen; Tamoxifen

2004
Inhibition of prostate carcinogenesis in probasin/SV40 T antigen transgenic rats by raloxifene, an antiestrogen with anti-androgen action, but not nimesulide, a selective cyclooxygenase-2 inhibitor.
    Carcinogenesis, 2005, Volume: 26, Issue:6

    Topics: Adenocarcinoma; Androgen Antagonists; Androgen-Binding Protein; Animals; Animals, Genetically Modified; Antigens, Polyomavirus Transforming; Apoptosis; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Drug Therapy, Combination; Male; Prostaglandin-Endoperoxide Synthases; Prostatic Neoplasms; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Receptors, Androgen; Sulfonamides; Testosterone

2005
Raloxifene (LY156758) produces antimetastatic responses and extends survival in the PAIII rat prostatic adenocarcinoma model.
    The Prostate, 1995, Volume: 27, Issue:4

    Topics: Adenocarcinoma; Adrenal Glands; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Estrogen Antagonists; Fluorouracil; Incidence; Lung Neoplasms; Lymphatic Metastasis; Male; Organ Size; Piperidines; Prostate; Prostatic Neoplasms; Raloxifene Hydrochloride; Random Allocation; Rats; Rats, Wistar; Survival Rate; Testis; Weight Gain

1995
Structure-activity relationships of selective estrogen receptor modulators: modifications to the 2-arylbenzothiophene core of raloxifene.
    Journal of medicinal chemistry, 1997, Jan-17, Volume: 40, Issue:2

    Topics: Adenocarcinoma; Animals; Binding Sites; Bone and Bones; Breast Neoplasms; Cell Division; Cholesterol; Estrogen Antagonists; Female; Humans; Male; Organ Size; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Structure-Activity Relationship; Uterus

1997
Blockade of the stimulatory effect of estrogens, OH-tamoxifen, OH-toremifene, droloxifene, and raloxifene on alkaline phosphatase activity by the antiestrogen EM-800 in human endometrial adenocarcinoma Ishikawa cells.
    Cancer research, 1997, Aug-15, Volume: 57, Issue:16

    Topics: Adenocarcinoma; Alkaline Phosphatase; Benzopyrans; Endometrial Neoplasms; Estradiol; Estrogen Antagonists; Female; Fulvestrant; Humans; Neoplasm Proteins; Piperidines; Propionates; Raloxifene Hydrochloride; Tamoxifen; Toremifene; Tumor Cells, Cultured

1997
Evaluation of the major metabolites of raloxifene as modulators of tissue selectivity.
    The Journal of steroid biochemistry and molecular biology, 1997, Volume: 61, Issue:1-2

    Topics: Adenocarcinoma; Animals; Bone Resorption; Breast Neoplasms; Cell Division; Cells, Cultured; Estradiol; Estrogen Antagonists; Female; Glucuronates; Humans; Interleukin-6; Organ Specificity; Osteoclasts; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Tissue Distribution; Transforming Growth Factor beta; Tumor Cells, Cultured

1997
Antiestrogens specifically up-regulate bone morphogenetic protein-4 promoter activity in human osteoblastic cells.
    Molecular endocrinology (Baltimore, Md.), 2000, Volume: 14, Issue:5

    Topics: Adenocarcinoma; Base Sequence; Bone Morphogenetic Protein 4; Bone Morphogenetic Proteins; Bone Neoplasms; Breast Neoplasms; Cells, Cultured; Dimerization; Drug Design; Endometrial Neoplasms; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Receptor Modulators; Estrogens; Female; Gene Expression Regulation; Humans; Molecular Sequence Data; Neoplasms, Hormone-Dependent; Organ Specificity; Osteoblasts; Osteogenesis; Osteoporosis; Osteosarcoma; Postmenopause; Promoter Regions, Genetic; Raloxifene Hydrochloride; Receptors, Estrogen; Recombinant Fusion Proteins; Stimulation, Chemical; Transfection; Tumor Cells, Cultured

2000
[Biochemical mechanism of raloxifen and tamoxifen action for the prevention of breast cancer. Studies in vitro].
    Ginekologia polska, 2000, Volume: 71, Issue:9

    Topics: Adenocarcinoma; Apoptosis; Breast Neoplasms; Cell Division; Estrogen Antagonists; Female; Humans; Raloxifene Hydrochloride; Selective Estrogen Receptor Modulators; Tamoxifen; Tumor Cells, Cultured

2000
Regulation of estrogen target genes and growth by selective estrogen-receptor modulators in endometrial cancer cells.
    Gynecologic oncology, 2002, Volume: 85, Issue:3

    Topics: Adenocarcinoma; Animals; Blotting, Northern; Cell Division; Endometrial Neoplasms; Endothelial Growth Factors; ErbB Receptors; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Receptor Modulators; Female; Luciferases; Lymphokines; Mice; Mice, Nude; Neoplasm Transplantation; Proteins; Raloxifene Hydrochloride; Receptor, ErbB-2; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Selective Estrogen Receptor Modulators; Tamoxifen; Transcription, Genetic; Trefoil Factor-1; Tumor Suppressor Proteins; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2002
Estrogen-stimulation of postconfluent cell accumulation and foci formation of human MCF-7 breast cancer cells.
    Journal of cellular biochemistry, 1991, Volume: 45, Issue:2

    Topics: Adenocarcinoma; Animals; Breast Neoplasms; Cattle; Cell Division; Contact Inhibition; Culture Media; Estradiol; Estrogens; Humans; Male; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Hormone-Dependent; Phenotype; Piperidines; Raloxifene Hydrochloride; Receptors, Estrogen; Tamoxifen; Tumor Cells, Cultured

1991