racemetirosine has been researched along with Pregnancy in 36 studies
alpha-Methyltyrosine: An inhibitor of the enzyme TYROSINE 3-MONOOXYGENASE, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with PHEOCHROMOCYTOMA. (Martindale, The Extra Pharmacopoeia, 30th ed)
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dopamine (DA) neurons participate in tonic inhibition of prolactin (PRL), whereas beta-endorphin (beta-End) and serotonin (5-HT) neurons appear to be important stimulatory links for nocturnal PRL surges that occur throughout the first half of pregnancy in the rat." | 3.68 | Mechanisms for the stimulatory effects of opioidergic and serotonergic input signals on prolactin in pregnant rats. ( Sagrillo, CA; Voogt, JL, 1992) |
| "Metastatic pheochromocytoma, a rare complication of pregnancy, was managed from 30 weeks' gestation until delivery three weeks later with a combination of alpha-adrenergic blockade (Minipres) beta-adrenergic blockade (Timolol), and dopamine synthesis inhibition (Demser)." | 3.67 | Metastatic pheochromocytoma in pregnancy and fetal biophysical assessment after maternal administration of alpha-adrenergic, beta-adrenergic, and dopamine antagonists. ( Castillo, RA; Devoe, LD; Hadi, HA; O'Dell, BE; Searle, N, 1986) |
| " Treatment of these rats with alpha-methyl-p-tyrosine, reserpine, or haloperidol for 1 or 2 days after mating increased the interestrous interval by a few days in all rats and to more than 8 days (leading to pseudopregnancy or pregnancy) in 20% of the cases." | 3.67 | Dopamine blockade reverses the inhibition of prolactin which results from intrahypothalamic pituitary grafts. ( Averill, RL, 1985) |
| "Adult female offspring of C57BL/6J mice injected daily with phenobarbital for the last third of pregnancy were more active than control offspring during a 3-min test period in an open field arena, thus confirming previous reports of lasting effects of prenatal exposure to phenobarbital." | 3.66 | Prenatal maternal phenobarbital increases reactivity and retards habituation of mature offspring to environmental stimuli. ( Middaugh, LD; Simpson, LW; Thomas, TN; Zemp, JW, 1981) |
| " To test this hypothesis we studied whether chronic administration of alpha-methyl-p-tyrosine, an inhibitor of tyrosine hydroxylase, to rats during gestation might prevent long-term deleterious effects of prenatal malnutrition on functional properties of interhemispheric connections of the visual cortex, and on asymmetry of visual evoked responses." | 1.30 | Prenatal malnutrition-induced functional alterations in callosal connections and in interhemispheric asymmetry in rats are prevented by reduction of noradrenaline synthesis during gestation. ( Alarcon, S; Belmar, J; Carreño, P; Hernández, A; Kusch, C; Pérez, H; Ruiz, S; Soto-Moyano, R, 1998) |
| "Pheochromocytoma is known to increase morbidity and mortality." | 1.30 | Diagnosis and management of pheochromocytoma during pregnancy: a case report. ( Hermayer, KL; Szpiech, M, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (47.22) | 18.7374 |
| 1990's | 12 (33.33) | 18.2507 |
| 2000's | 5 (13.89) | 29.6817 |
| 2010's | 2 (5.56) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lifantseva, NV | 1 |
| Koneeva, TO | 1 |
| Voronova, SN | 1 |
| Zakharova, LA | 1 |
| Melnikova, VI | 1 |
| Izvolskaia, M | 1 |
| Duittoz, AH | 1 |
| Tillet, Y | 1 |
| Ugrumov, MV | 2 |
| Saifetyarova, JY | 1 |
| Lavrentieva, AV | 1 |
| Sapronova, AY | 1 |
| Sakka, N | 1 |
| Sawada, H | 1 |
| Izumi, Y | 1 |
| Kume, T | 1 |
| Katsuki, H | 1 |
| Kaneko, S | 1 |
| Shimohama, S | 1 |
| Akaike, A | 1 |
| Zhang, XJ | 1 |
| Li, Z | 1 |
| Leung, WM | 1 |
| Liu, L | 1 |
| Xu, HX | 1 |
| Bian, ZX | 1 |
| Walker, RF | 1 |
| Ladosky, W | 1 |
| Azambuja, HM | 1 |
| Schneider, HT | 1 |
| Erinoff, L | 1 |
| Kelly, PH | 1 |
| Basura, M | 1 |
| Snodgrass, SR | 1 |
| Nagy, G | 2 |
| Bánky, Z | 1 |
| Takács, L | 1 |
| Halász, B | 1 |
| Wise, PM | 1 |
| Middaugh, LD | 1 |
| Simpson, LW | 1 |
| Thomas, TN | 1 |
| Zemp, JW | 1 |
| Plotsky, PM | 1 |
| Neill, JD | 1 |
| Rosengarten, H | 1 |
| Friedman, E | 1 |
| Friedhoff, AJ | 1 |
| Trembleau, A | 1 |
| Ugrumov, M | 1 |
| Roche, D | 1 |
| Calas, A | 1 |
| Vathy, I | 1 |
| Rimanoczy, A | 1 |
| Eaton, RC | 1 |
| Katay, L | 1 |
| Criswell, HE | 1 |
| Johnson, KB | 1 |
| Mueller, RA | 1 |
| Breese, GR | 1 |
| Héry, M | 1 |
| François-Bellan, AM | 1 |
| Deprez, P | 1 |
| Faudon, M | 1 |
| Héry, F | 1 |
| Becker, HC | 1 |
| Hale, RL | 1 |
| Boggan, WO | 1 |
| Randall, CL | 1 |
| Moy, SS | 1 |
| Elwan, MA | 1 |
| Sakuragawa, N | 1 |
| Soto-Moyano, R | 1 |
| Alarcon, S | 1 |
| Hernández, A | 1 |
| Pérez, H | 1 |
| Ruiz, S | 1 |
| Carreño, P | 1 |
| Kusch, C | 1 |
| Belmar, J | 1 |
| Hermayer, KL | 1 |
| Szpiech, M | 1 |
| Bolaños, CA | 1 |
| Trksak, GH | 1 |
| Glatt, SJ | 1 |
| Jackson, D | 1 |
| McNamara, JP | 1 |
| Murray, CE | 1 |
| Seidler, FJ | 1 |
| Levin, ED | 1 |
| Lappi, SE | 1 |
| Slotkin, TA | 1 |
| Sagrillo, CA | 1 |
| Voogt, JL | 1 |
| Bellavía, SL | 1 |
| Sanz, EG | 1 |
| Sereno, R | 1 |
| Vermouth, NT | 1 |
| Fung, YK | 1 |
| Arbogast, LA | 1 |
| Murai, I | 2 |
| Ben-Jonathan, N | 2 |
| Devoe, LD | 1 |
| O'Dell, BE | 1 |
| Castillo, RA | 1 |
| Hadi, HA | 1 |
| Searle, N | 1 |
| Hagino, N | 1 |
| Inoue, K | 1 |
| Brioni, JD | 1 |
| Keller, EA | 1 |
| Levin, LE | 1 |
| Córdoba, N | 1 |
| Orsingher, OA | 1 |
| Averill, RL | 1 |
| Selmanoff, M | 1 |
| Gregerson, KA | 1 |
36 other studies available for racemetirosine and Pregnancy
| Article | Year |
|---|---|
The inhibition of dopamine synthesis in fetuses changes the pattern of T-lymphocyte maturation in the thymus of adult rats.
Topics: alpha-Methyltyrosine; Animals; Cells, Cultured; Dopamine; Enzyme Inhibitors; Female; Pregnancy; Pren | 2016 |
The influence of catecholamine on the migration of gonadotropin-releasing hormone-producing neurons in the rat foetuses.
Topics: alpha-Methyltyrosine; Animals; Catecholamines; Cell Movement; Chromatography, High Pressure Liquid; | 2009 |
Developing brain as an endocrine organ: secretion of dopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Blood-Brain Barrier; Brain; Dopamine; | 2012 |
Dopamine is involved in selectivity of dopaminergic neuronal death by rotenone.
Topics: alpha-Methyltyrosine; Animals; Cell Death; Cell Survival; Cells, Cultured; Dopamine; Dose-Response R | 2003 |
The analgesic effect of paeoniflorin on neonatal maternal separation-induced visceral hyperalgesia in rats.
Topics: Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Animals; Animals, Newborn; Anti-Inflammatory Age | 2008 |
Reinstatement of LH surges by serotonin neuroleptics in aging, constant estrous rats.
Topics: 5-Hydroxytryptophan; Aging; alpha-Methyltyrosine; Animals; Antipsychotic Agents; Castration; Estradi | 1982 |
Possible mechanism of action of 2-hydroxylated estradiol on the positive feedback control for LH release in the rat.
Topics: alpha-Methyltyrosine; Animals; Castration; Catechol O-Methyltransferase; Estradiol; Estrogens, Catec | 1983 |
Six-hydroxydopamine induced hyperactivity: neither sex differences nor caffeine stimulation are found.
Topics: Aging; alpha-Methyltyrosine; Animals; Body Weight; Brain; Brain Chemistry; Caffeine; Catecholamines; | 1984 |
Rapid decrease of plasma prolactin levels in lactating rats separated from their pups.
Topics: alpha-Methyltyrosine; Animals; Female; Haloperidol; Hypophysectomy; Kinetics; Lactation; Methyltyros | 1983 |
Time course of the litter removal-induced depletion in plasma prolactin levels of lactating rats. An immediate full blockade of the hormone release after separation.
Topics: alpha-Methyltyrosine; Animals; Female; Haloperidol; Lactation; Levodopa; Maternal Behavior; Methylty | 1983 |
Norepinephrine and dopamine activity in microdissected brain areas of the middle-aged and young rat on proestrus.
Topics: Age Factors; alpha-Methyltyrosine; Animals; Brain; Brain Chemistry; Dissection; Dopamine; Estrus; Fe | 1982 |
Prenatal maternal phenobarbital increases reactivity and retards habituation of mature offspring to environmental stimuli.
Topics: alpha-Methyltyrosine; Animals; Brain Chemistry; Dopamine; Environment; Female; Habituation, Psychoph | 1981 |
Interactions of dopamine and thyrotropin-releasing hormone in the regulation of prolactin release in lactating rats.
Topics: alpha-Methyltyrosine; Animals; Dopamine; Drug Interactions; Female; Lactation; Methyltyrosines; Preg | 1982 |
Sensitive periods for the effect of haloperidol on development of striatal dopamine receptors.
Topics: alpha-Methyltyrosine; Animals; Corpus Striatum; Dopamine; Female; Gestational Age; Haloperidol; Levo | 1983 |
Vasopressin and oxytocin gene expression in intact rats and under catecholamine deficiency during ontogenesis.
Topics: alpha-Methyltyrosine; Animals; Animals, Newborn; Catecholamines; Female; Gene Expression Regulation, | 1995 |
Modulation of catecholamine turnover rate in brain regions of rats exposed prenatally to morphine.
Topics: alpha-Methyltyrosine; Animals; Brain Chemistry; Catecholamines; Chromatography, High Pressure Liquid | 1994 |
Evidence for involvement of brain dopamine and other mechanisms in the behavioral action of the N-methyl-D-aspartic acid antagonist MK-801 in control and 6-hydroxydopamine-lesioned rats.
Topics: alpha-Methyltyrosine; Animals; Animals, Newborn; Behavior, Animal; Brain; Dizocilpine Maleate; Dopam | 1993 |
Evidence for the presence of noradrenergic neurons and their inhibitory action on luteinizing hormone-releasing hormone release in cultured fetal rat hypothalamic cells.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; alpha-Methyltyrosine; Animals; Cells, Cultu | 1993 |
Effects of prenatal ethanol exposure on later sensitivity to the low-dose stimulant actions of ethanol in mouse offspring: possible role of catecholamines.
Topics: Age Factors; Alcohol Drinking; alpha-Methyltyrosine; Animals; Arousal; Brain; Catecholamines; Ethano | 1993 |
Impaired acquisition and operant responding after neonatal dopamine depletion in rats.
Topics: alpha-Methyltyrosine; Animals; Animals, Newborn; Behavior, Animal; Caudate Nucleus; Conditioning, Op | 1995 |
Evidence for synthesis and release of catecholamines by human amniotic epithelial cells.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Amnion; Catecholamines; Cells, Cultured; Chrom | 1997 |
Prenatal malnutrition-induced functional alterations in callosal connections and in interhemispheric asymmetry in rats are prevented by reduction of noradrenaline synthesis during gestation.
Topics: alpha-Methyltyrosine; Animals; Brain; Electric Stimulation; Enzyme Inhibitors; Evoked Potentials, Vi | 1998 |
Diagnosis and management of pheochromocytoma during pregnancy: a case report.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenergic Antagonists; Adult; alpha-Methyltyrosine; Catecho | 1999 |
Prenatal cocaine exposure increases serotonergic inhibition of electrically evoked acetylcholine release from rat striatal slices at adulthood.
Topics: Acetylcholine; alpha-Methyltyrosine; Animals; Biguanides; Cocaine; Dopamine; Dopamine Uptake Inhibit | 2000 |
Sympathetic nervous system activity in adipose tissues during pregnancy and lactation of the rat.
Topics: Adaptation, Physiological; Adipose Tissue; Adrenergic alpha-Agonists; alpha-Methyltyrosine; Animals; | 2001 |
Fetal nicotine exposure ablates the ability of postnatal nicotine challenge to release norepinephrine from rat brain regions.
Topics: alpha-Methyltyrosine; Animals; Brain; Cerebral Cortex; Female; Fetus; Hippocampus; Infusions, Parent | 1992 |
Mechanisms for the stimulatory effects of opioidergic and serotonergic input signals on prolactin in pregnant rats.
Topics: alpha-Methyltyrosine; Animals; beta-Endorphin; Bromocriptine; Circadian Rhythm; Dopamine; Female; Ha | 1992 |
Alpha-amylase circadian rhythm of young rat parotid gland: an endogenous rhythm with maternal coordination.
Topics: Aging; alpha-Amylases; alpha-Methyltyrosine; Animals; Circadian Rhythm; Female; Food Deprivation; Li | 1992 |
Postnatal effects of maternal nicotine exposure on the striatal dopaminergic system in rats.
Topics: alpha-Methyltyrosine; Animals; Corpus Striatum; Dextroamphetamine; Dopamine; Female; In Vitro Techni | 1989 |
Differential alterations in dopamine turnover rates in the stalk-median eminence and posterior pituitary during the preovulatory prolactin surge.
Topics: alpha-Methyltyrosine; Animals; Dopamine; Female; Horses; Median Eminence; Methyltyrosines; Ovulation | 1989 |
Metastatic pheochromocytoma in pregnancy and fetal biophysical assessment after maternal administration of alpha-adrenergic, beta-adrenergic, and dopamine antagonists.
Topics: Adult; alpha-Methyltyrosine; Catecholamines; Drug Therapy, Combination; Female; Fetal Heart; Fetal M | 1986 |
Hypothalamic dopamine may play a role in inducing prolactin in pituitary cells.
Topics: alpha-Methyltyrosine; Animals; Dopamine; Female; Fetus; Gestational Age; Hypothalamus; Immunohistoch | 1986 |
Posterior pituitary lobectomy abolishes the suckling-induced rise in prolactin (PRL): evidence for a PRL-releasing factor in the posterior pituitary.
Topics: 5-Hydroxytryptophan; alpha-Methyltyrosine; Animals; Deamino Arginine Vasopressin; Dopamine; Drinking | 1987 |
Reactivity to amphetamine in perinatally undernourished rats: behavioral and neurochemical correlates.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Amphetamine; Animals; Behavior, Animal; Brain | 1986 |
Dopamine blockade reverses the inhibition of prolactin which results from intrahypothalamic pituitary grafts.
Topics: alpha-Methyltyrosine; Animals; Diestrus; Dopamine; Dopamine Antagonists; Estrus; Female; Haloperidol | 1985 |
Suckling decreases dopamine turnover in both medial and lateral aspects of the median eminence in the rat.
Topics: alpha-Methyltyrosine; Animals; Dopamine; Female; Hypothalamo-Hypophyseal System; Lactation; Median E | 1985 |