Page last updated: 2024-10-26

racemetirosine and Pain

racemetirosine has been researched along with Pain in 6 studies

alpha-Methyltyrosine: An inhibitor of the enzyme TYROSINE 3-MONOOXYGENASE, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with PHEOCHROMOCYTOMA. (Martindale, The Extra Pharmacopoeia, 30th ed)

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"Propranolol is a non-selective β adrenergic receptor blocker which antagonises the anti-inflammatory effect of non-steroidal anti-inflammatory drugs via the β1 and β2 adrenergic receptors."1.37Effects of epinephrine and cortisol on the analgesic activity of metyrosine in rats. ( Akcay, F; Albayrak, Y; Karatay, S; Polat, B; Saglam, MB; Suleyman, H; Uslu, T; Yildirim, K, 2011)
"When baclofen was administered intraperitoneally, pretreatment with depletors of monoamines and catecholamines (reserpine, alpha-MPT) produced a marked increase in antinociceptive activity in both tests."1.27Monoamines as mediators of the antinociceptive effect of baclofen. ( Sawynok, J, 1983)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Albayrak, Y1
Saglam, MB1
Yildirim, K1
Karatay, S1
Polat, B1
Uslu, T1
Suleyman, H1
Akcay, F1
Marchand, F1
Alloui, A1
Chapuy, E1
Jourdan, D1
Pelissier, T1
Ardid, D1
Hernandez, A1
Eschalier, A1
Fusa, K1
Takahashi, I1
Watanabe, S1
Aono, Y1
Ikeda, H1
Saigusa, T1
Nagase, H1
Suzuki, T1
Koshikawa, N1
Cools, AR1
Sawynok, J1
Saphier, D1
Feldman, S1
Mantz, J1
Milla, C1
Glowinski, J1
Thierry, AM1

Other Studies

6 other studies available for racemetirosine and Pain

ArticleYear
Effects of epinephrine and cortisol on the analgesic activity of metyrosine in rats.
    Archives of pharmacal research, 2011, Volume: 34, Issue:9

    Topics: Adrenergic beta-Antagonists; alpha-Methyltyrosine; Analgesics; Animals; Carrageenan; Chromatography,

2011
Evidence for a monoamine mediated, opioid-independent, antihyperalgesic effect of venlafaxine, a non-tricyclic antidepressant, in a neurogenic pain model in rats.
    Pain, 2003, Volume: 103, Issue:3

    Topics: alpha-Methyltyrosine; Analgesics; Animals; Antidepressive Agents; Cyclohexanols; Disease Models, Ani

2003
The non-peptidic delta opioid receptor agonist TAN-67 enhances dopamine efflux in the nucleus accumbens of freely moving rats via a mechanism that involves both glutamate and free radicals.
    Neuroscience, 2005, Volume: 130, Issue:3

    Topics: Adrenergic Uptake Inhibitors; alpha-Methyltyrosine; Animals; Dopamine; Enkephalin, D-Penicillamine (

2005
Monoamines as mediators of the antinociceptive effect of baclofen.
    Naunyn-Schmiedeberg's archives of pharmacology, 1983, Volume: 323, Issue:1

    Topics: alpha-Methyltyrosine; Analgesics; Animals; Baclofen; Biogenic Amines; Male; Methyltyrosines; Pain; R

1983
Catecholaminergic projections to tuberoinfundibular neurones of the paraventricular nucleus: II. Effects of stimulation of the ventral noradrenergic ascending bundle: evidence for cotransmission.
    Brain research bulletin, 1989, Volume: 23, Issue:6

    Topics: Action Potentials; alpha-Methyltyrosine; Animals; Brain Stem; Electric Stimulation; Hydroxydopamines

1989
Differential effects of ascending neurons containing dopamine and noradrenaline in the control of spontaneous activity and of evoked responses in the rat prefrontal cortex.
    Neuroscience, 1988, Volume: 27, Issue:2

    Topics: alpha-Methyltyrosine; Animals; Cerebral Cortex; Dopamine; Electric Stimulation; Evoked Potentials; H

1988