racemetirosine has been researched along with Nerve Degeneration in 3 studies
alpha-Methyltyrosine: An inhibitor of the enzyme TYROSINE 3-MONOOXYGENASE, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with PHEOCHROMOCYTOMA. (Martindale, The Extra Pharmacopoeia, 30th ed)
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| " It is known that dopamine (DA) enhances this toxic effect." | 1.35 | Endogenous dopamine enhances the neurotoxicity of 3-nitropropionic acid in the striatum through the increase of mitochondrial respiratory inhibition and free radicals production. ( Cano, J; de Pablos, RM; Herrera, AJ; Machado, A; Navarro, A; Santiago, M; Tomás-Camardiel, M; Villarán, RF, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dong, Z | 1 |
| Ferger, B | 1 |
| Paterna, JC | 1 |
| Vogel, D | 1 |
| Furler, S | 1 |
| Osinde, M | 1 |
| Feldon, J | 1 |
| Büeler, H | 1 |
| Park, SS | 1 |
| Schulz, EM | 1 |
| Lee, D | 1 |
| Villarán, RF | 1 |
| Tomás-Camardiel, M | 1 |
| de Pablos, RM | 1 |
| Santiago, M | 1 |
| Herrera, AJ | 1 |
| Navarro, A | 1 |
| Machado, A | 1 |
| Cano, J | 1 |
3 other studies available for racemetirosine and Nerve Degeneration
| Article | Year |
|---|---|
Dopamine-dependent neurodegeneration in rats induced by viral vector-mediated overexpression of the parkin target protein, CDCrel-1.
Topics: alpha-Methyltyrosine; Animals; Animals, Genetically Modified; Base Sequence; Cell Cycle Proteins; Co | 2003 |
Disruption of dopamine homeostasis underlies selective neurodegeneration mediated by alpha-synuclein.
Topics: Alanine; alpha-Methyltyrosine; alpha-Synuclein; Animals; Animals, Genetically Modified; Cells, Cultu | 2007 |
Endogenous dopamine enhances the neurotoxicity of 3-nitropropionic acid in the striatum through the increase of mitochondrial respiratory inhibition and free radicals production.
Topics: alpha-Methyltyrosine; Animals; Apoptosis; Astrocytes; Cell Respiration; Corpus Striatum; Dopamine; D | 2008 |