racemetirosine has been researched along with Inadequate Sleep in 7 studies
alpha-Methyltyrosine: An inhibitor of the enzyme TYROSINE 3-MONOOXYGENASE, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with PHEOCHROMOCYTOMA. (Martindale, The Extra Pharmacopoeia, 30th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Furthermore, mood effects following sleep deprivation plus AMPT suggest that catecholamines may be involved in mood changes during sleep deprivation." | 2.67 | Effects of catecholamine depletion on alertness and mood in rested and sleep deprived normal volunteers. ( Belenky, G; Gillin, JC; McCann, UD; Penetar, DM; Shaham, Y; Sing, HC; Thomas, ML; Thorne, DR, 1993) |
| "Treatment with AMPT or treatment with sleep deprivation increased sleepiness without producing marked or consistent deterioration in performance." | 2.67 | Sleep deprivation and impaired cognition. Possible role of brain catecholamines. ( Belenky, G; Gillin, JC; McCann, UD; Penetar, DM; Shaham, Y; Sing, HC; Thomas, MA; Thorne, DR, 1992) |
| " The dose-response relationship shifted to the left following REMs deprivation (ED50 values in the group-housed, isolated, and REMs-deprived mice were 250, 200, and 27 micrograms/kg, respectively)." | 1.29 | Monoamine depletion attenuates the REM sleep deprivation-induced increase in clonidine response in the forced swimming test. ( Asakura, W; Matsumoto, K; Ohta, H; Watanabe, H, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 5 (71.43) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lima, MM | 1 |
| Andersen, ML | 1 |
| Reksidler, AB | 1 |
| Ferraz, AC | 1 |
| Vital, MA | 1 |
| Tufik, S | 1 |
| Kitahama, K | 1 |
| Valatx, JL | 1 |
| Jouvet, M | 1 |
| Asakura, W | 2 |
| Matsumoto, K | 2 |
| Ohta, H | 2 |
| Watanabe, H | 2 |
| McCann, UD | 3 |
| Penetar, DM | 3 |
| Shaham, Y | 2 |
| Thorne, DR | 2 |
| Sing, HC | 2 |
| Thomas, ML | 1 |
| Gillin, JC | 2 |
| Belenky, G | 3 |
| Thomas, MA | 1 |
2 trials available for racemetirosine and Inadequate Sleep
| Article | Year |
|---|---|
Effects of catecholamine depletion on alertness and mood in rested and sleep deprived normal volunteers.
Topics: Adult; Affect; alpha-Methyltyrosine; Analysis of Variance; Arousal; Catecholamines; Double-Blind Met | 1993 |
Sleep deprivation and impaired cognition. Possible role of brain catecholamines.
Topics: Adult; Affect; alpha-Methyltyrosine; Analysis of Variance; Arousal; Brain Chemistry; Catecholamines; | 1992 |
5 other studies available for racemetirosine and Inadequate Sleep
| Article | Year |
|---|---|
Paradoxical sleep deprivation modulates tyrosine hydroxylase expression in the nigrostriatal pathway and attenuates motor deficits induced by dopaminergic depletion.
Topics: alpha-Methyltyrosine; Animals; Disease Models, Animal; Dopamine; Dopaminergic Neurons; Down-Regulati | 2012 |
Paradoxical sleep deprivation and performance of an active avoidance task: impairment of c57BR mice and no effect in c57BL/6 mice.
Topics: alpha-Methyltyrosine; Animals; Attention; Avoidance Learning; Clomipramine; Discrimination Learning; | 1981 |
Monoamine depletion attenuates the REM sleep deprivation-induced increase in clonidine response in the forced swimming test.
Topics: Adrenergic alpha-2 Receptor Antagonists; alpha-Methyltyrosine; Animals; Biogenic Monoamines; Brain C | 1994 |
Involvement of dopamine D2 receptor mechanism in the REM sleep deprivation-induced increase in swimming activity in the forced swimming test.
Topics: alpha-Methyltyrosine; Animals; Benzazepines; Biogenic Monoamines; Disulfiram; Dopamine D2 Receptor A | 1994 |
Panic attacks in healthy volunteers treated with a catecholamine synthesis inhibitor.
Topics: Adult; alpha-Methyltyrosine; Double-Blind Method; Humans; Male; Methyltyrosines; Panic Disorder; Ran | 1991 |