racemetirosine has been researched along with Huntington Disease in 2 studies
alpha-Methyltyrosine: An inhibitor of the enzyme TYROSINE 3-MONOOXYGENASE, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with PHEOCHROMOCYTOMA. (Martindale, The Extra Pharmacopoeia, 30th ed)
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "He had a negative evaluation for malignant hyperthermia (MH), and we suggest that NMS differs from MH." | 1.26 | Neuroleptic malignant syndrome caused by dopamine-depleting drugs in a patient with Huntington disease. ( Burke, RE; Fahn, S; Louis, K; Mayeux, R; Weinberg, H; Willner, JH, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ortiz, AN | 1 |
| Kurth, BJ | 1 |
| Osterhaus, GL | 1 |
| Johnson, MA | 1 |
| Burke, RE | 1 |
| Fahn, S | 1 |
| Mayeux, R | 1 |
| Weinberg, H | 1 |
| Louis, K | 1 |
| Willner, JH | 1 |
2 other studies available for racemetirosine and Huntington Disease
| Article | Year |
|---|---|
Dysregulation of intracellular dopamine stores revealed in the R6/2 mouse striatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; alpha-Methyltyrosine; Animals; Biophysics; | 2010 |
Neuroleptic malignant syndrome caused by dopamine-depleting drugs in a patient with Huntington disease.
Topics: Adolescent; Adult; alpha-Methyltyrosine; Antipsychotic Agents; Child; Dopamine; Dystonia; Female; Fe | 1981 |