racemetirosine has been researched along with Glioma in 5 studies
alpha-Methyltyrosine: An inhibitor of the enzyme TYROSINE 3-MONOOXYGENASE, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with PHEOCHROMOCYTOMA. (Martindale, The Extra Pharmacopoeia, 30th ed)
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To develop a valid treatment strategy for recurrent high-grade gliomas using stereotactic hypofractionated reirradiation based on biologic imaging and temozolomide." | 3.73 | Reirradiation of recurrent high-grade gliomas using amino acid PET (SPECT)/CT/MRI image fusion to determine gross tumor volume for stereotactic fractionated radiotherapy. ( Franz, M; Grosu, AL; Gumprecht, H; Molls, M; Nieder, C; Piert, M; Schwaiger, M; Stärk, S; Thamm, R; Weber, WA, 2005) |
| "The highest IMT uptake was found in a metastasis of lung carcinoma." | 1.31 | I-123-lodo-alpha-methyl tyrosine SPECT in non-parenchymal brain tumours. ( Franzius, Ch; Matheja, P; Palkovic, S; Rickert, Ch; Riemann, B; Schober, O; Weckesser, M, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Matheja, P | 2 |
| Weckesser, M | 3 |
| Rickert, Ch | 1 |
| Franzius, Ch | 1 |
| Palkovic, S | 1 |
| Riemann, B | 3 |
| Schober, O | 3 |
| Papke, K | 1 |
| Hoess, N | 1 |
| Kuwert, T | 1 |
| Wassmann, H | 1 |
| Heindel, W | 1 |
| Grosu, AL | 1 |
| Weber, WA | 1 |
| Franz, M | 1 |
| Stärk, S | 1 |
| Piert, M | 1 |
| Thamm, R | 1 |
| Gumprecht, H | 1 |
| Schwaiger, M | 1 |
| Molls, M | 1 |
| Nieder, C | 1 |
| Kopka, K | 1 |
| Friedrich, M | 1 |
| Winters, S | 1 |
| Halfter, H | 1 |
| Stögbauer, F | 1 |
| Ringelstein, EB | 1 |
| Samnick, S | 1 |
| Bader, JB | 1 |
| Hellwig, D | 1 |
| Moringlane, JR | 1 |
| Alexander, C | 1 |
| Romeike, BF | 1 |
| Feiden, W | 1 |
| Kirsch, CM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Amino-acid PET Versus MRI Guided Re-irradiation in Patients With Recurrent Glioblastoma Multiforme - a Randomised Phase II Trial[NCT01252459] | Phase 2 | 200 participants (Anticipated) | Interventional | 2011-07-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for racemetirosine and Glioma
| Article | Year |
|---|---|
Clinical value of iodine-123-alpha-methyl-L-tyrosine single-photon emission tomography in the differential diagnosis of recurrent brain tumor in patients pretreated for glioma at follow-up.
Topics: Adult; alpha-Methyltyrosine; Brain Neoplasms; Diagnosis, Differential; Enzyme Inhibitors; Female; Gl | 2002 |
4 other studies available for racemetirosine and Glioma
| Article | Year |
|---|---|
I-123-lodo-alpha-methyl tyrosine SPECT in non-parenchymal brain tumours.
Topics: Adult; Aged; alpha-Methyltyrosine; Biological Transport; Biopsy; Brain Neoplasms; Female; Glioma; Hu | 2002 |
Noninvasive grading of untreated gliomas: a comparative study of MR imaging and 3-(iodine 123)-L-alpha-methyltyrosine SPECT.
Topics: Adult; Aged; Aged, 80 and over; alpha-Methyltyrosine; Astrocytoma; Biopsy; Brain; Brain Neoplasms; F | 2002 |
Reirradiation of recurrent high-grade gliomas using amino acid PET (SPECT)/CT/MRI image fusion to determine gross tumor volume for stereotactic fractionated radiotherapy.
Topics: Adult; Aged; alpha-Methyltyrosine; Analysis of Variance; Antineoplastic Agents, Alkylating; Astrocyt | 2005 |
Characterization of 3-[(123)I]iodo-L-alpha-methyl tyrosine transport in astrocytes of neonatal rats.
Topics: alpha-Methyltyrosine; Amino Acid Transport Systems; Amino Acids, Cyclic; Animals; Animals, Newborn; | 2001 |