racemetirosine has been researched along with Depression, Involutional in 6 studies
alpha-Methyltyrosine: An inhibitor of the enzyme TYROSINE 3-MONOOXYGENASE, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with PHEOCHROMOCYTOMA. (Martindale, The Extra Pharmacopoeia, 30th ed)
Depression, Involutional: Form of depression in those MIDDLE AGE with feelings of ANXIETY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pathophysiologic mechanism of major depressive disorder (MDD) has been consistently associated with altered catecholaminergic function, especially with decreased dopamine neurotransmission, by various sources of largely indirect evidence." | 2.73 | Neural response to catecholamine depletion in unmedicated subjects with major depressive disorder in remission and healthy subjects. ( Carlson, PJ; Charney, DS; Drevets, WC; Fromm, S; Geraci, M; Hasler, G; Luckenbaugh, DA; Meyers, N; Neumeister, A; Roiser, JP; Waldeck, T, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Homan, P | 3 |
| Drevets, WC | 5 |
| Hasler, G | 5 |
| Mondillo, K | 1 |
| Blair, JR | 1 |
| Fromm, S | 1 |
| Carlson, PJ | 1 |
| Luckenbaugh, DA | 1 |
| Waldeck, T | 1 |
| Geraci, M | 1 |
| Roiser, JP | 1 |
| Neumeister, A | 1 |
| Meyers, N | 1 |
| Charney, DS | 2 |
| Berman, RM | 1 |
| Sanacora, G | 1 |
| Anand, A | 1 |
| Roach, LM | 1 |
| Fasula, MK | 1 |
| Finkelstein, CO | 1 |
| Wachen, RM | 1 |
| Oren, DA | 1 |
| Heninger, GR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Neuronal Correlates of Catecholamine Depletion in Patients With Bulimia Nervosa Off Medication and Healthy Controls[NCT02179814] | 60 participants (Anticipated) | Interventional | 2012-02-20 | Suspended (stopped due to Conduct of the first analyses) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 trials available for racemetirosine and Depression, Involutional
| Article | Year |
|---|---|
Neural correlates of free T3 alteration after catecholamine depletion in subjects with remitted major depressive disorder and in controls.
Topics: Adolescent; Adult; alpha-Methyltyrosine; Case-Control Studies; Catecholamines; Cross-Over Studies; D | 2014 |
Growth hormone response to catecholamine depletion in unmedicated, remitted subjects with major depressive disorder and healthy controls.
Topics: Administration, Oral; Adult; alpha-Methyltyrosine; Catecholamines; Cross-Over Studies; Depressive Di | 2013 |
The effects of catecholamine depletion on the neural response to fearful faces in remitted depression.
Topics: Adolescent; Adult; alpha-Methyltyrosine; Amphetamine; Catecholamines; Central Nervous System Stimula | 2014 |
Impairments of probabilistic response reversal and passive avoidance following catecholamine depletion.
Topics: Adolescent; Adult; alpha-Methyltyrosine; Avoidance Learning; Brain; Catecholamines; Conditioning, Op | 2009 |
Neural response to catecholamine depletion in unmedicated subjects with major depressive disorder in remission and healthy subjects.
Topics: Adolescent; Adult; alpha-Methyltyrosine; Brain; Catecholamines; Corpus Striatum; Cross-Over Studies; | 2008 |
Monoamine depletion in unmedicated depressed subjects.
Topics: Adult; alpha-Methyltyrosine; Catecholamines; Depressive Disorder, Major; Diphenhydramine; Dopamine; | 2002 |