racemetirosine has been researched along with Bulimia Nervosa in 4 studies
alpha-Methyltyrosine: An inhibitor of the enzyme TYROSINE 3-MONOOXYGENASE, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with PHEOCHROMOCYTOMA. (Martindale, The Extra Pharmacopoeia, 30th ed)
Bulimia Nervosa: An eating disorder that is characterized by a cycle of binge eating (BULIMIA or bingeing) followed by inappropriate acts (purging) to avert weight gain. Purging methods often include self-induced VOMITING, use of LAXATIVES or DIURETICS, excessive exercise, and FASTING.
| Excerpt | Relevance | Reference |
|---|---|---|
| "As bulimia nervosa has been associated with a dysregulated dopamine system and catecholamine depletion led to reward-processing deficits in remitted bulimia nervosa, the purpose of this study was to identify the role of catecholamine dysfunction and its relation to behavioral and neural reward-effort integration in bulimia nervosa." | 1.48 | Neural Correlates of Impaired Reward-Effort Integration in Remitted Bulimia Nervosa. ( Federspiel, A; Hasler, G; Morishima, Y; Mueller, SV; Schwab, S; Wiest, R, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mueller, SV | 1 |
| Morishima, Y | 1 |
| Schwab, S | 1 |
| Wiest, R | 1 |
| Federspiel, A | 1 |
| Hasler, G | 4 |
| Grob, S | 3 |
| Stern, J | 2 |
| Gamper, L | 1 |
| Moergeli, H | 1 |
| Milos, G | 3 |
| Schnyder, U | 3 |
| Homan, P | 1 |
| Eckert, A | 1 |
| Lang, U | 1 |
| Pizzagalli, DA | 1 |
| Dutra, SJ | 1 |
| Mörgeli, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Neuronal Correlates of Catecholamine Depletion in Patients With Bulimia Nervosa Off Medication and Healthy Controls[NCT02179814] | 60 participants (Anticipated) | Interventional | 2012-02-20 | Suspended (stopped due to Conduct of the first analyses) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for racemetirosine and Bulimia Nervosa
| Article | Year |
|---|---|
Behavioral responses to catecholamine depletion in unmedicated, remitted subjects with bulimia nervosa and healthy subjects.
Topics: Adult; alpha-Methyltyrosine; Bulimia Nervosa; Catecholamines; Central Nervous System Agents; Cross-O | 2015 |
Dopamine-related deficit in reward learning after catecholamine depletion in unmedicated, remitted subjects with bulimia nervosa.
Topics: Adult; alpha-Methyltyrosine; Bulimia Nervosa; Catecholamines; Conditioning, Operant; Discrimination, | 2012 |
2 other studies available for racemetirosine and Bulimia Nervosa
| Article | Year |
|---|---|
Neural Correlates of Impaired Reward-Effort Integration in Remitted Bulimia Nervosa.
Topics: Adult; alpha-Methyltyrosine; Brain; Bulimia Nervosa; Enzyme Inhibitors; Female; Follow-Up Studies; H | 2018 |
The role of BDNF, leptin, and catecholamines in reward learning in bulimia nervosa.
Topics: Adult; alpha-Methyltyrosine; Association Learning; Body Mass Index; Brain-Derived Neurotrophic Facto | 2014 |