Page last updated: 2024-10-26

racemetirosine and Bipolar Disorder

racemetirosine has been researched along with Bipolar Disorder in 3 studies

alpha-Methyltyrosine: An inhibitor of the enzyme TYROSINE 3-MONOOXYGENASE, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with PHEOCHROMOCYTOMA. (Martindale, The Extra Pharmacopoeia, 30th ed)

Bipolar Disorder: A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence.

Research Excerpts

ExcerptRelevanceReference
"This study investigated the effects of catecholamine depletion with alpha-methylparatyrosine (AMPT) on mood indices in patients with bipolar disorder who were in long-term remission with lithium therapy."9.09Effect of catecholamine depletion on lithium-induced long-term remission of bipolar disorder. ( Anand, A; Berman, RM; Cappiello, A; Charney, DS; Darnell, A; Miller, HL; Oren, DA; Woods, SW, 1999)
"This study investigated the effects of catecholamine depletion with alpha-methylparatyrosine (AMPT) on mood indices in patients with bipolar disorder who were in long-term remission with lithium therapy."5.09Effect of catecholamine depletion on lithium-induced long-term remission of bipolar disorder. ( Anand, A; Berman, RM; Cappiello, A; Charney, DS; Darnell, A; Miller, HL; Oren, DA; Woods, SW, 1999)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kwiatkowski, MA1
Hellemann, G1
Sugar, CA1
Cope, ZA1
Minassian, A1
Perry, W1
Geyer, MA2
Young, JW2
van Enkhuizen, J1
Halberstadt, AL1
Zhuang, X1
Anand, A1
Darnell, A1
Miller, HL1
Berman, RM1
Cappiello, A1
Oren, DA1
Woods, SW1
Charney, DS1

Reviews

1 review available for racemetirosine and Bipolar Disorder

ArticleYear
Dopamine transporter knockdown mice in the behavioral pattern monitor: A robust, reproducible model for mania-relevant behaviors.
    Pharmacology, biochemistry, and behavior, 2019, Volume: 178

    Topics: alpha-Methyltyrosine; Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Cohort Studies;

2019

Trials

1 trial available for racemetirosine and Bipolar Disorder

ArticleYear
Effect of catecholamine depletion on lithium-induced long-term remission of bipolar disorder.
    Biological psychiatry, 1999, Apr-15, Volume: 45, Issue:8

    Topics: Adult; alpha-Methyltyrosine; Antimanic Agents; Bipolar Disorder; Catecholamines; Double-Blind Method

1999

Other Studies

1 other study available for racemetirosine and Bipolar Disorder

ArticleYear
Dopamine depletion attenuates some behavioral abnormalities in a hyperdopaminergic mouse model of bipolar disorder.
    Journal of affective disorders, 2014, Volume: 155

    Topics: alpha-Methyltyrosine; Animals; Bipolar Disorder; Disease Models, Animal; Dopamine; Dopamine Plasma M

2014