racecadotril has been researched along with Heart Failure in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (69.23) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goldstein, S; Mishima, T; Sabbah, HN; Sharov, VG; Suzuki, G; Tanhehco, EJ; Tanimura, M; Todor, A | 1 |
| Hirth-Dietrich, C; Knorr, A; Stasch, JP; Wegner, M | 1 |
| Wilkins, MR | 1 |
| Hirth-Dietrich, C; Stasch, JP; Wegner, M | 1 |
| Cleland, JG; Swedberg, K | 1 |
| Burnett, JC; Cody, RJ; Elkayam, U; Gattis, WA; Gheorghiade, M; Gilbert, J; Goldstein, S; Granger, CB; Kasper, EK; Katz, SD; Massie, BM; McKenney, JM; Messineo, FC; O'Connor, CM | 1 |
| Beals, S; Hanson, B; Kutas, SM; Olivier, NB; Windram, S | 1 |
| Goetze, L; Maertins, T; von Keutz, E | 1 |
| Goetze, L; Sisson, D; Solter, P; Thomas, W | 1 |
| Duboc, D; Fouchard, J; Guérin, F; Muffat-Joly, M; Schwartz, JC; Varin, J; Weber, S | 1 |
| Hirata, Y | 1 |
| Castaigne, A; Duboc, D; Dubois-Rande, JL; Gros, C; Kahn, JC; Lecomte, JM; Lim-Alexandre, C; Merlet, P; Patey, M; Schwartz, JC | 1 |
2 review(s) available for racecadotril and Heart Failure
| Article | Year |
|---|---|
Clinical potential of endopeptidase-24.11 inhibitors in cardiovascular disease.
Topics: Animals; Antihypertensive Agents; Cardiovascular Diseases; Cyclohexanecarboxylic Acids; Diuretics; Drug Design; Heart Failure; Humans; Hypertension; Indans; Neprilysin; Propionates; Protease Inhibitors; Thiorphan | 1993 |
[Effect of sinorphan, an endopeptidase inhibitor on severe congestive cardiac insufficiency].
Topics: Adult; Aged; Atrial Natriuretic Factor; Blood Pressure; Creatinine; Cyclic GMP; Diuresis; Female; Heart Failure; Humans; Male; Middle Aged; Natriuresis; Neprilysin; Thiorphan | 1991 |
4 trial(s) available for racecadotril and Heart Failure
| Article | Year |
|---|---|
Lack of efficacy of neutral endopeptidase inhibitor ecadotril in heart failure. The International Ecadotril Multi-centre Dose-ranging Study Investigators.
Topics: Anemia, Aplastic; Dose-Response Relationship, Drug; Female; Heart Failure; Humans; Male; Middle Aged; Neprilysin; Protease Inhibitors; Thiorphan | 1998 |
A randomized trial of ecadotril versus placebo in patients with mild to moderate heart failure: the U.S. ecadotril pilot safety study.
Topics: Adolescent; Adult; Aged; Double-Blind Method; Female; Heart Failure; Humans; Male; Middle Aged; Pilot Projects; Prodrugs; Severity of Illness Index; Thiorphan; Time Factors; Treatment Outcome | 1999 |
[Effect of sinorphan, an endopeptidase inhibitor on severe congestive cardiac insufficiency].
Topics: Adult; Aged; Atrial Natriuretic Factor; Blood Pressure; Creatinine; Cyclic GMP; Diuresis; Female; Heart Failure; Humans; Male; Middle Aged; Natriuresis; Neprilysin; Thiorphan | 1991 |
Effect of sinorphan on plasma atrial natriuretic factor in congestive heart failure.
Topics: Administration, Oral; Atrial Natriuretic Factor; Clinical Trials as Topic; Drug Administration Schedule; Heart Failure; Humans; Male; Neprilysin; Stimulation, Chemical; Thiorphan | 1990 |
8 other study(ies) available for racecadotril and Heart Failure
| Article | Year |
|---|---|
Effects of chronic neutral endopeptidase inhibition on the progression of left ventricular dysfunction and remodeling in dogs with moderate heart failure.
Topics: Animals; Chronic Disease; Coronary Angiography; Dogs; Heart Failure; Hemodynamics; Myocytes, Cardiac; Neprilysin; Thiorphan; Ventricular Dysfunction, Left; Ventricular Remodeling | 2002 |
Prolonged inhibition of neutral endopeptidase 24.11 by sinorphan in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Heart Failure; Hemodynamics; Kidney Function Tests; Neprilysin; Rats; Rats, Inbred SHR; Sodium, Dietary; Thiorphan; Time Factors | 1995 |
Role of neutral endopeptidase 24.11 in AV fistular rat model of heart failure.
Topics: Angiotensin I; Animals; Aorta; Arteriovenous Fistula; Atrial Natriuretic Factor; Disease Models, Animal; Heart Failure; Natriuretic Peptide, Brain; Neprilysin; Nerve Tissue Proteins; Protease Inhibitors; Rats; Rats, Sprague-Dawley; Renin; Sodium; Thiorphan; Venae Cavae | 1996 |
Ecadotril. (S)-acetorphan, sinorphan.
Topics: Animals; Cardiovascular Diseases; Drugs, Investigational; Endopeptidases; Heart Failure; Humans; Hypertension; Protease Inhibitors; Rats; Rats, Inbred SHR; Thiorphan | 1999 |
Short-term effects of ecadotril in dogs with induced congestive heart failure.
Topics: Animals; Cyclic GMP; Dog Diseases; Dogs; Electrocardiography; Heart Failure; Hemodynamics; Male; Microspheres; Potassium; Protease Inhibitors; Random Allocation; Sodium; Thiorphan | 2000 |
Acute, subchronic, and chronic toxicity of ecadotril in dogs.
Topics: Animals; Dog Diseases; Dogs; Drug Administration Schedule; Heart Failure; Neprilysin; Prodrugs; Protease Inhibitors; Thiorphan | 2000 |
Intrarenal effects of ecadotril during acute volume expansion in dogs with congestive heart failure.
Topics: Animals; Atrial Natriuretic Factor; Dogs; Glomerular Filtration Rate; Heart Failure; Kidney; Male; Neprilysin; Protease Inhibitors; Renal Circulation; Thiorphan | 2000 |
[Clinical significance and therapeutic application of atrial natriuretic peptides].
Topics: Animals; Atrial Natriuretic Factor; Glycopeptides; Heart Atria; Heart Failure; Hemodynamics; Humans; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface; Thiorphan | 1991 |