Page last updated: 2024-11-03

rabeprazole and Peptic Ulcer

rabeprazole has been researched along with Peptic Ulcer in 65 studies

Rabeprazole: A 4-(3-methoxypropoxy)-3-methylpyridinyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.

Peptic Ulcer: Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

Research Excerpts

ExcerptRelevanceReference
" We aimed to clarify the efficacy of rabeprazole for preventing peptic ulcer, esophagitis, and gastrointestinal symptoms associated with LDA."9.16Rabeprazole reduces the recurrence risk of peptic ulcers associated with low-dose aspirin in patients with cardiovascular or cerebrovascular disease: a prospective randomized active-controlled trial. ( Azuma, T; Fujisawa, T; Fujita, T; Hayakumo, T; Inokuchi, H; Kawai, T; Kutsumi, H; Kuwayama, H; Matsubara, Y; Miyaji, H; Murakami, M; Sanuki, T; Terao, S; Yamazaki, Y; Yoshida, S, 2012)
" As a result, clopidogrel's incidence of peptic ulcer disease (PUD) and ulcer bleeding is lower than aspirin's."9.15Randomised clinical trial: rabeprazole plus aspirin is not inferior to rabeprazole plus clopidogrel for the healing of aspirin-related peptic ulcer. ( Chen, LC; Hou, MC; Huang, KW; Lee, FY; Lee, SD; Leu, HB; Li, CP; Lin, HC; Lu, CL; Luo, JC, 2011)
"Low-dose rabeprazole 10 mg has a similar efficacy for the healing rapidity of active peptic ulcer disease and symptom improvement compared with standard-dose omeprazole 20 mg."9.12Comparison of the efficacy of rabeprazole 10 mg and omeprazole 20 mg for the healing rapidity of peptic ulcer diseases. ( Baik, SK; Jee, MK; Ji, S; Kim, HS; Kim, JW; Kwon, SO; Lee, DK; Park, KW; Song, JS; Uh, Y, 2006)
"To study the efficacy and safety of rabeprazole in peptic ulcer patients alone or combined with anti-Helicobacter pylori (Hp) agents."9.11[The clinical applications of rabeprazole either alone or combined with anti-Helicobacter pylori agents in peptic ulcer patients]. ( Lin, SR, 2005)
" pylori-positive patients with peptic ulcer disease were received rabeprazole 10 mg bid, amoxicillin 1,000 mg bid and clarithromycin 500 mg bid for a week."9.10[A prospective study on rabeprazole-based triple therapy for Helicobacter pylori eradication in patients with peptic ulcer]. ( Choi, BK; Chung, JM; Jang, YS; Lee, SH; Lee, YJ; Park, ET; Seol, SY; Yang, SY, 2003)
" pylori-infected peptic ulcer patients were randomly assigned to 1 of 3 groups: RAC4 (rabeprazole 20 mg, amoxicillin 1000 mg, and clarithromycin 500 mg twice daily for 4 days), RAC7 (rabeprazole 20 mg, amoxicillin 1000 mg, and clarithromycin 500 mg twice daily for 7 days), and OAC7 (omeprazole 20mg, amoxicillin 1000 mg, and clarithromycin 500 mg twice daily for 7 days)."9.10Comparison of rabeprazole-based four- and seven-day triple therapy and omeprazole-based seven-day triple therapy for Helicobacter pylori infection in patients with peptic ulcer. ( Chen, JH; Chen, TJ; Lee, SC; Wang, GM; Yang, KC, 2003)
"In this randomised, double-blind, multicentre study, conducted at 27 European sites, the efficacy and safety of rabeprazole and omeprazole were compared in patients with erosive or ulcerative gastro-oesophageal reflux disease (GERD)."9.09Double-blind comparison [correction of Double-blind, placebo-controlled comparison] of rabeprazole 20 mg vs. omeprazole 20 mg in the treatment of erosive or ulcerative gastro-oesophageal reflux disease. The European Rabeprazole Study Group. ( Beker, JA; Bell, NE; Dekkers, CP; Gabryelewicz, A; Humphries, TJ; Thjodleifsson, B, 1999)
"Rabeprazole is a new fast acting proton pump inhibitor that has recently been proven to be effective in the treatment of peptic ulceration and reflux esophagitis."9.08Safety and efficacy of rabeprazole in combination with four antibiotic regimens for the eradication of Helicobacter pylori in patients with chronic gastritis with or without peptic ulceration. ( Atherton, JC; Cockayne, A; Hawkey, CJ; Jenkins, D; Knifton, A; Stack, WA; Thirlwell, D, 1998)
"Kangfuxin (KFX), a well-known Chinese patent medicine which extracted from Periplaneta americana, is widely used as an adjuvant in the treatment of peptic ulcers (PUs) with proton pump inhibitors (PPIs) such as rabeprazole, in China."9.05Therapeutic efficacy and safety of Kangfuxin in combination with rabeprazole in the treatment of peptic ulcer: A systematic review and meta-analysis. ( Gao, F; Lin, M; Luo, R; Shi, J; Sun, J; You, J; Zhang, C; Zhang, J; Zhang, M; Zhang, S, 2020)
"The study was intended to develop a new intra-gastric floating in situ microballoons system for controlled delivery of rabeprazole sodium and amoxicillin trihydrate for the treatment of peptic ulcer disease."7.83Stomach specific polymeric low density microballoons as a vector for extended delivery of rabeprazole and amoxicillin for treatment of peptic ulcer. ( Agrawal, GP; Amin, MCIM; Choudhary, S; Jain, A; Kesharwani, P; Mishra, V, 2016)
" We aimed to clarify the efficacy of rabeprazole for preventing peptic ulcer, esophagitis, and gastrointestinal symptoms associated with LDA."5.16Rabeprazole reduces the recurrence risk of peptic ulcers associated with low-dose aspirin in patients with cardiovascular or cerebrovascular disease: a prospective randomized active-controlled trial. ( Azuma, T; Fujisawa, T; Fujita, T; Hayakumo, T; Inokuchi, H; Kawai, T; Kutsumi, H; Kuwayama, H; Matsubara, Y; Miyaji, H; Murakami, M; Sanuki, T; Terao, S; Yamazaki, Y; Yoshida, S, 2012)
" As a result, clopidogrel's incidence of peptic ulcer disease (PUD) and ulcer bleeding is lower than aspirin's."5.15Randomised clinical trial: rabeprazole plus aspirin is not inferior to rabeprazole plus clopidogrel for the healing of aspirin-related peptic ulcer. ( Chen, LC; Hou, MC; Huang, KW; Lee, FY; Lee, SD; Leu, HB; Li, CP; Lin, HC; Lu, CL; Luo, JC, 2011)
"Two hundred and forty Chinese with peptic ulcer disease were randomly assigned to the following regimens: amoxicillin and clarithromycin together with omeprazole (OAC) or rabeprazole (RAC)."5.14The effect of cytochrome P2C19 and interleukin-1 polymorphisms on H. pylori eradication rate of 1-week triple therapy with omeprazole or rabeprazole, amoxycillin and clarithromycin in Chinese people. ( Hu, YM; Li, QS; Mei, Q; Xu, JM; Zhang, L, 2010)
"Low-dose rabeprazole 10 mg has a similar efficacy for the healing rapidity of active peptic ulcer disease and symptom improvement compared with standard-dose omeprazole 20 mg."5.12Comparison of the efficacy of rabeprazole 10 mg and omeprazole 20 mg for the healing rapidity of peptic ulcer diseases. ( Baik, SK; Jee, MK; Ji, S; Kim, HS; Kim, JW; Kwon, SO; Lee, DK; Park, KW; Song, JS; Uh, Y, 2006)
"To study the efficacy and safety of rabeprazole in peptic ulcer patients alone or combined with anti-Helicobacter pylori (Hp) agents."5.11[The clinical applications of rabeprazole either alone or combined with anti-Helicobacter pylori agents in peptic ulcer patients]. ( Lin, SR, 2005)
" pylori-infected peptic ulcer patients were randomly assigned to 1 of 3 groups: RAC4 (rabeprazole 20 mg, amoxicillin 1000 mg, and clarithromycin 500 mg twice daily for 4 days), RAC7 (rabeprazole 20 mg, amoxicillin 1000 mg, and clarithromycin 500 mg twice daily for 7 days), and OAC7 (omeprazole 20mg, amoxicillin 1000 mg, and clarithromycin 500 mg twice daily for 7 days)."5.10Comparison of rabeprazole-based four- and seven-day triple therapy and omeprazole-based seven-day triple therapy for Helicobacter pylori infection in patients with peptic ulcer. ( Chen, JH; Chen, TJ; Lee, SC; Wang, GM; Yang, KC, 2003)
" pylori-infected peptic ulcer patients were randomly treated with either rabeprazole (10 mg b."5.10Effect of different proton pump inhibitors, differences in CYP2C19 genotype and antibiotic resistance on the eradication rate of Helicobacter pylori infection by a 1-week regimen of proton pump inhibitor, amoxicillin and clarithromycin. ( Habu, Y; Hayakumo, T; Inokuchi, H; Kawabata, H; Kawai, K; Kimoto, K; Kiyota, K; Kobayashi, M; Kutsumi, H; Mizuno, S; Nakajima, M; Oyasu, K; Tomioka, H, 2003)
" pylori-positive gastritis or peptic ulcers were randomly assigned to receive 30 mg lansoprazole twice daily (LAC group), 10 mg rabeprazole twice daily (RAC20 group), or 20 mg rabeprazole twice daily (RAC40 group), with 1000 mg amoxicillin twice daily and 400 mg clarithromycin twice daily for 1 week."5.10Impact of clarithromycin resistance and CYP2C19 genetic polymorphism on treatment efficacy of Helicobacter pylori infection with lansoprazole- or rabeprazole-based triple therapy in Japan. ( Aoyama, N; Kasuga, M; Kita, T; Kuroda, K; Maekawa, S; Miki, I; Okumura, K; Sakaeda, T; Sakai, T; Shirasaka, D; Tamura, T; Wambura, CM, 2003)
" pylori-positive patients with peptic ulcer disease were received rabeprazole 10 mg bid, amoxicillin 1,000 mg bid and clarithromycin 500 mg bid for a week."5.10[A prospective study on rabeprazole-based triple therapy for Helicobacter pylori eradication in patients with peptic ulcer]. ( Choi, BK; Chung, JM; Jang, YS; Lee, SH; Lee, YJ; Park, ET; Seol, SY; Yang, SY, 2003)
"In this randomised, double-blind, multicentre study, conducted at 27 European sites, the efficacy and safety of rabeprazole and omeprazole were compared in patients with erosive or ulcerative gastro-oesophageal reflux disease (GERD)."5.09Double-blind comparison [correction of Double-blind, placebo-controlled comparison] of rabeprazole 20 mg vs. omeprazole 20 mg in the treatment of erosive or ulcerative gastro-oesophageal reflux disease. The European Rabeprazole Study Group. ( Beker, JA; Bell, NE; Dekkers, CP; Gabryelewicz, A; Humphries, TJ; Thjodleifsson, B, 1999)
"Rabeprazole is a new fast acting proton pump inhibitor that has recently been proven to be effective in the treatment of peptic ulceration and reflux esophagitis."5.08Safety and efficacy of rabeprazole in combination with four antibiotic regimens for the eradication of Helicobacter pylori in patients with chronic gastritis with or without peptic ulceration. ( Atherton, JC; Cockayne, A; Hawkey, CJ; Jenkins, D; Knifton, A; Stack, WA; Thirlwell, D, 1998)
"Kangfuxin (KFX), a well-known Chinese patent medicine which extracted from Periplaneta americana, is widely used as an adjuvant in the treatment of peptic ulcers (PUs) with proton pump inhibitors (PPIs) such as rabeprazole, in China."5.05Therapeutic efficacy and safety of Kangfuxin in combination with rabeprazole in the treatment of peptic ulcer: A systematic review and meta-analysis. ( Gao, F; Lin, M; Luo, R; Shi, J; Sun, J; You, J; Zhang, C; Zhang, J; Zhang, M; Zhang, S, 2020)
" Rabeprazole is a potent and irreversible inhibitor of H(+)/K(+)-ATPase gastric pump, and it is indicated for the treatment of gastroesophageal reflux disease, Zollinger Ellison syndrome, duodenal and gastric ulcers and for the eradication of Helicobacter pylori in combination with antibiotics."4.88Rabeprazole for the treatment of acid-related disorders. ( Marelli, S; Pace, F, 2012)
"Rabeprazole (Aciphex, Alfence, Pariet) is a proton pump inhibitor (PPI) used for the treatment of adults with conditions requiring a reduction of gastric acid secretion such as erosive or ulcerative gastro-oesophageal reflux disease (GORD), non-erosive reflux disease (NERD), duodenal and gastric ulcers, and pathological hypersecretory conditions including Zollinger-Ellison syndrome (ZES)."4.85Rabeprazole: a review of its use in the management of gastric acid-related diseases in adults. ( Baldwin, CM; Keam, SJ, 2009)
" Pharmacodynamic results have also suggested that rabeprazole may be better suited than omeprazole as on-demand therapy for symptomatic gastro-oesophageal reflux disease."4.82Review article: relationship between the metabolism and efficacy of proton pump inhibitors--focus on rabeprazole. ( Horn, J, 2004)
"The study was intended to develop a new intra-gastric floating in situ microballoons system for controlled delivery of rabeprazole sodium and amoxicillin trihydrate for the treatment of peptic ulcer disease."3.83Stomach specific polymeric low density microballoons as a vector for extended delivery of rabeprazole and amoxicillin for treatment of peptic ulcer. ( Agrawal, GP; Amin, MCIM; Choudhary, S; Jain, A; Kesharwani, P; Mishra, V, 2016)
"To investigate whether or not CYP2C19 genotype status is associated with cure rate for Helicobacter pylori infection in patients with cirrhosis and peptic ulcer, achieved with 2 weeks of triple therapy with rabeprazole, amoxicillin and clarithromycin."3.76Correlation of CYP2C19 genetic polymorphisms with helicobacter pylori eradication in patients with cirrhosis and peptic ulcer. ( Lay, CS; Lin, CJ; Lin, JR, 2010)
" For the rate of adverse events, there was no significant difference among all the PPIs, vonoprazan, and placebo."2.82Efficacy and safety of proton pump inhibitors versus vonoprazan in treatment of erosive esophagitis: A PRISMA-compliant systematic review and network meta-analysis. ( Chen, J; Deng, W; Xie, Z; Yang, S, 2022)
"Rabeprazole is a new proton pump inhibitor, which has been reported to induce a faster acid suppression than other drugs of the same category."2.71Comparable Helicobacter pylori eradication rates obtained with 4- and 7-day rabeprazole-based triple therapy: a preliminary study. ( Bilardi, C; Dulbecco, P; Gambaro, C; Iiritano, E; Mansia, C; Savarino, V; Usai, P; Vigneri, S; Zentilin, P, 2003)
" We determined the therapeutic effects of sofalcone and polaprezinc when combined with rabeprazole, amoxicillin and clarithromycin for Helicobacter pylori infection."2.71Sofalcone, a mucoprotective agent, increases the cure rate of Helicobacter pylori infection when combined with rabeprazole, amoxicillin and clarithromycin. ( Furusu, H; Inoue, K; Isomoto, H; Kohno, S; Ohnita, K; Wen, CY, 2005)
" One of the key distinguishing features of rabeprazole was related to the lesser involvement of polymorphic metabolism in its pharmacokinetic disposition."2.58Stereoselective and nonstereoselective pharmacokinetics of rabeprazole - an overview. ( Dash, RP; Rais, R; Srinivas, NR, 2018)
"Rabeprazole is a newer generation proton pump inhibitor that suppresses the gastric proton pump and acid secretion more rapidly than does omeprazole, lansoprazole or pantoprazole."2.42Review article: relief of symptoms in gastric acid-related diseases--correlation with acid suppression in rabeprazole treatment. ( Miner, P, 2004)
"Rabeprazole is a proton pump inhibitor with antisecretory properties."2.40Rabeprazole. ( Faulds, D; Prakash, A, 1998)
"Rabeprazole was similar to omeprazole and superior to placebo in both maintenance of healing and prevention of symptoms in patients with healed GERD in 1-year studies."2.40Rabeprazole: a review of its use in acid-related gastrointestinal disorders. ( Langtry, HD; Markham, A, 1999)

Research

Studies (65)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (6.15)18.2507
2000's44 (67.69)29.6817
2010's13 (20.00)24.3611
2020's4 (6.15)2.80

Authors

AuthorsStudies
Jain, KS1
Shah, AK1
Bariwal, J1
Shelke, SM1
Kale, AP1
Jagtap, JR1
Bhosale, AV1
Kinoshita, Y2
Kato, M1
Sugizaki, K1
Ikeuchi, S1
Yang, S3
Deng, W3
Xie, Z3
Chen, J3
Tang, Y1
Tang, G1
Pan, L1
Zhu, H1
Zhou, S1
Wei, Z1
Lin, M1
Zhang, S1
Zhang, M1
Shi, J1
Zhang, C1
Luo, R1
You, J1
Sun, J1
Zhang, J1
Gao, F1
Liu, MK1
Wu, IC1
Lu, CY1
Kuo, CH1
Yu, FJ1
Liu, CJ1
Hsu, PI1
Hsu, WH1
Su, YC1
Chen, A1
Wu, DC1
Kuo, FC1
Chen, JJ1
Chung, KH1
Lee, DH1
Jin, E1
Cho, Y1
Seo, JY1
Kim, N1
Jeong, SH1
Kim, JW2
Hwang, JH1
Shin, CM1
Choudhary, S1
Jain, A1
Amin, MCIM1
Mishra, V1
Agrawal, GP1
Kesharwani, P1
Chan, FK1
Kyaw, M1
Tanigawa, T1
Higuchi, K1
Fujimoto, K1
Cheong, PK1
Lee, V1
Naito, Y1
Watanabe, T1
Ching, JY1
Lam, K1
Lo, A1
Chan, H1
Lui, R1
Tang, RS1
Sakata, Y1
Tse, YK1
Takeuchi, T1
Handa, O1
Nebiki, H1
Wu, JC1
Abe, T2
Mishiro, T1
Ng, SC1
Arakawa, T1
Dash, RP1
Rais, R1
Srinivas, NR1
Hong, EJ1
Park, DI1
Oh, SJ1
Song, MJ1
Choi, WH1
Hong, CH1
Park, JH1
Kim, HJ1
Cho, YK1
Shon, CI1
Jeon, WK1
Kim, BI1
Baldwin, CM1
Keam, SJ1
Jain, SC1
Niwa, Y1
Nakamura, M1
Miyahara, R1
Ohmiya, N1
Watanabe, O1
Ando, T1
Kawashima, H1
Itoh, A1
Hirooka, Y1
Goto, H1
Lay, CS1
Lin, CJ1
Lin, JR1
Vovolis, V1
Christogianni, K1
Koutsostathis, N1
Zhang, L1
Mei, Q1
Li, QS1
Hu, YM1
Xu, JM1
Luo, JC1
Huang, KW1
Leu, HB1
Chen, LC1
Hou, MC1
Li, CP1
Lu, CL1
Lin, HC1
Lee, FY1
Lee, SD1
Park, HG1
Jung, MK1
Jung, JT1
Kwon, JG1
Kim, EY1
Seo, HE1
Lee, JH1
Yang, CH1
Kim, ES1
Cho, KB1
Park, KS1
Lee, SH2
Kim, KO1
Jeon, SW1
Sanuki, T1
Fujita, T1
Kutsumi, H2
Hayakumo, T2
Yoshida, S1
Inokuchi, H2
Murakami, M1
Matsubara, Y1
Kuwayama, H3
Kawai, T2
Miyaji, H1
Fujisawa, T1
Terao, S1
Yamazaki, Y1
Azuma, T1
Uotani, T1
Sugimoto, M1
Nishino, M1
Kodaira, C1
Yamade, M1
Sahara, S1
Yamada, T2
Osawa, S1
Sugimoto, K1
Tanaka, T1
Umemura, K1
Watanabe, H1
Miyajima, H1
Furuta, T1
Marelli, S1
Pace, F1
Inaba, T1
Mizuno, M2
Kawai, K2
Yokota, K2
Oguma, K2
Miyoshi, M2
Take, S1
Okada, H2
Tsuji, T2
Vanderhoff, BT1
Tahboub, RM1
Johnson, M1
Guilford, S1
Libretto, SE1
De Francesco, V4
Faleo, D1
Panella, C3
Ierardi, E4
Margiotta, M2
Kawakami, K1
Kudo, T1
Ogiahara, S1
Handa, Y1
Moriyasu, F1
Go, MF1
Nemytin, IuV1
Makarov, IuS1
Pavlov, AI1
Kashchenko, OI1
Lezhenina, NP1
Golochalova, TV1
Kawabata, H1
Habu, Y1
Tomioka, H1
Kobayashi, M1
Oyasu, K1
Mizuno, S1
Kiyota, K1
Nakajima, M1
Kimoto, K1
Miki, I1
Aoyama, N2
Sakai, T1
Shirasaka, D1
Wambura, CM1
Maekawa, S1
Kuroda, K1
Tamura, T1
Kita, T1
Sakaeda, T1
Okumura, K1
Kasuga, M1
Hawkey, CJ2
Atherton, JC2
Treichel, HC1
Thjodleifsson, B2
Ravic, M1
Choi, BK1
Yang, SY1
Park, ET1
Jang, YS1
Lee, YJ1
Seol, SY1
Chung, JM1
Luo, JY1
Niu, CY1
Wang, XQ1
Zhu, YL1
Gong, J1
Gambaro, C1
Bilardi, C1
Dulbecco, P1
Iiritano, E1
Zentilin, P1
Mansia, C1
Usai, P1
Vigneri, S1
Savarino, V1
Zullo, A3
Marangi, S1
Burattini, O1
Berloco, P1
Russo, F1
Barone, M1
Di Leo, A1
Minenna, MF2
Stoppino, V2
Morini, S3
Francavilla, A1
Yang, KC1
Wang, GM1
Chen, JH1
Chen, TJ1
Lee, SC1
Sharara, AI1
Chaar, HF1
Racoubian, E1
Moukhachen, O1
Barada, KA1
Mourad, FH1
Araj, GF1
Hassan, C2
Della Valle, N1
Pietrini, L1
Winn, S1
Monno, R1
de Korwin, JD1
Ducrotté, P1
Vallot, T1
Horn, J1
Miner, P1
Isomoto, H1
Furusu, H1
Ohnita, K1
Wen, CY1
Inoue, K1
Kohno, S1
Lin, SR1
Gatta, L1
Ricci, C1
Bernabucci, V1
Cavina, M1
Vaira, D1
Calvet, X2
Ducons, J1
Bujanda, L1
Bory, F1
Montserrat, A1
Gisbert, JP1
Wang, F1
Wang, XY1
Jia, Y1
Shen, SR1
Xu, CX1
Tang, WL1
Liu, SJ1
Chen, X1
Gomollón, F1
Murakami, K3
Sato, R2
Okimoto, T3
Watanabe, K2
Nasu, M1
Fujioka, T4
Kodama, M3
Sato, S1
Arita, T1
Ji, S1
Kim, HS1
Jee, MK1
Park, KW1
Uh, Y1
Lee, DK1
Song, JS1
Baik, SK1
Kwon, SO1
Asaka, M1
Sugiyama, T1
Fukuda, Y1
Hirai, Y1
Belousov, IuB1
Karpov, OI1
Belousov, DIu1
Beketov, AS1
Prakash, A1
Faulds, D1
Stack, WA1
Knifton, A1
Thirlwell, D1
Cockayne, A1
Jenkins, D1
Dekkers, CP1
Beker, JA1
Gabryelewicz, A1
Bell, NE1
Humphries, TJ1
Langtry, HD1
Markham, A1
Hizawa, K1
Nakahara, T1
Yano, Y1
Inuzuka, S1
Akagi, K1
Matsumoto, T1
Satoh, R1
Kagawa, J1
Lüth, S1
Teyssen, S1
Kölbel, CB1
Singer, MV1
Nagahara, A1
Miwa, H1
Ohkura, R1
Sato, K1
Hojo, M1
Sato, N1
Ishiki, K1
Nagahara, Y1
Maga, T1
Torigoe, T1
Nasu, J1
Barth, J1
Hahne, W1
Fu, HY1
Kawano, S1
Tanimura, H1
Takahashi, M1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Histamine-2 Receptor Antagonist Versus Proton-Pump Inhibitor for the Prevention of Recurrent Upper Gastrointestinal Bleeding (UGI) in High-risk Users of Low-dose Aspirin (ASA)[NCT01408186]Phase 3264 participants (Actual)Interventional2011-01-31Completed
Comparison of Ulcer Healing in Patients Taking Rabeprazole Plus Aspirin Versus Rabeprazole Plus Clopidogrel for Acute Peptic Ulcer[NCT01037491]200 participants (Anticipated)Interventional2009-10-31Recruiting
Comparative Recurrence Rate Investigation of Esomeprazole Versus Lansoprazole in Triple-Combination Therapy to Eradicate Helicobacter Pylori Infection Among Pediatrics: Multicentre, Randomized, and Controlled Trials[NCT05861687]Phase 2/Phase 351 participants (Actual)Interventional2021-08-01Completed
Rifaximin Associated With Classic Triple Therapy (Inhibitor of Proton Pump, Amoxicillin and Clarithromycin) for the Eradication of Helicobacter Pylori Infection[NCT03124199]Phase 340 participants (Actual)Interventional2014-02-28Completed
Phase 4, Prospective, Randomized and Comparative Study Comparing Sequential and Concomitant Therapy for Helicobacter Pylori Eradication in Routine Clinical Practice[NCT01273441]Phase 4338 participants (Actual)Interventional2010-12-31Completed
Sequential Therapy Versus Triple Therapy for Helicobacter Pylori Eradication: a Placebo-controlled Trial[NCT00403364]Phase 2/Phase 3300 participants Interventional2003-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Compliance With Treatment of Patients That Completed the Study

Percentage of patients that has comply with treatment, considered as intake of more than 90% of study drugs in patients who attended the post-treatment visit. (NCT03124199)
Timeframe: 1 month

Interventionpercentage of participants (Number)
Rifaximin100

Percentage of Participants With H.Pylori Infection Eradication

Percentage of Participants with H.Pylori Infection Eradication confirmed with urea breath test at least 4 weeks after the end of treatment (NCT03124199)
Timeframe: 1 month

Interventionpercentage of participants (Number)
Rifaximin61

Tolerability of Treatment

Patients with side effects present during treatment and in the 4 weeks after end of treatment (NCT03124199)
Timeframe: 1 month

Interventionparticipants (Number)
with diarrheawith metallic tasteheadachenauseaabdominal pain
Rifaximin139551

Reviews

17 reviews available for rabeprazole and Peptic Ulcer

ArticleYear
Recent advances in proton pump inhibitors and management of acid-peptic disorders.
    Bioorganic & medicinal chemistry, 2007, Feb-01, Volume: 15, Issue:3

    Topics: Animals; Anti-Ulcer Agents; Gastric Acid; Gastroesophageal Reflux; Helicobacter Infections; Humans;

2007
Efficacy and safety of proton pump inhibitors versus vonoprazan in treatment of erosive esophagitis: A PRISMA-compliant systematic review and network meta-analysis.
    Medicine, 2022, Nov-25, Volume: 101, Issue:47

    Topics: Abdominal Injuries; Esomeprazole; Esophagitis, Peptic; Humans; Network Meta-Analysis; Peptic Ulcer;

2022
Efficacy and safety of proton pump inhibitors versus vonoprazan in treatment of erosive esophagitis: A PRISMA-compliant systematic review and network meta-analysis.
    Medicine, 2022, Nov-25, Volume: 101, Issue:47

    Topics: Abdominal Injuries; Esomeprazole; Esophagitis, Peptic; Humans; Network Meta-Analysis; Peptic Ulcer;

2022
Efficacy and safety of proton pump inhibitors versus vonoprazan in treatment of erosive esophagitis: A PRISMA-compliant systematic review and network meta-analysis.
    Medicine, 2022, Nov-25, Volume: 101, Issue:47

    Topics: Abdominal Injuries; Esomeprazole; Esophagitis, Peptic; Humans; Network Meta-Analysis; Peptic Ulcer;

2022
Efficacy and safety of proton pump inhibitors versus vonoprazan in treatment of erosive esophagitis: A PRISMA-compliant systematic review and network meta-analysis.
    Medicine, 2022, Nov-25, Volume: 101, Issue:47

    Topics: Abdominal Injuries; Esomeprazole; Esophagitis, Peptic; Humans; Network Meta-Analysis; Peptic Ulcer;

2022
Therapeutic efficacy and safety of Kangfuxin in combination with rabeprazole in the treatment of peptic ulcer: A systematic review and meta-analysis.
    Medicine, 2020, Nov-25, Volume: 99, Issue:48

    Topics: Drug Therapy, Combination; Humans; Materia Medica; Peptic Ulcer; Proton Pump Inhibitors; Rabeprazole

2020
Stereoselective and nonstereoselective pharmacokinetics of rabeprazole - an overview.
    Xenobiotica; the fate of foreign compounds in biological systems, 2018, Volume: 48, Issue:4

    Topics: Animals; Drug Interactions; Gastroesophageal Reflux; Humans; Peptic Ulcer; Proton Pump Inhibitors; R

2018
Rabeprazole: a review of its use in the management of gastric acid-related diseases in adults.
    Drugs, 2009, Jul-09, Volume: 69, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Bacterial Agents; Gastric Acid; Gastroesophagea

2009
Rabeprazole for the treatment of acid-related disorders.
    Expert review of gastroenterology & hepatology, 2012, Volume: 6, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Enzyme Inhibitors; Gastroesophageal Refl

2012
Treatment and management of Helicobacter pylori infection.
    Current gastroenterology reports, 2002, Volume: 4, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Inflammatory Agent

2002
[New-generation proton pump inhibitors: progress in the treatment of peptic acid diseases?].
    Presse medicale (Paris, France : 1983), 2004, Jun-19, Volume: 33, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Anti-Ulcer Agents; Benzimidazole

2004
Review article: relationship between the metabolism and efficacy of proton pump inhibitors--focus on rabeprazole.
    Alimentary pharmacology & therapeutics, 2004, Volume: 20 Suppl 6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; Benzimida

2004
Review article: relief of symptoms in gastric acid-related diseases--correlation with acid suppression in rabeprazole treatment.
    Alimentary pharmacology & therapeutics, 2004, Volume: 20 Suppl 6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Esophagitis; Gastric Aci

2004
What is potent acid inhibition, and how can it be achieved?
    Drugs, 2005, Volume: 65 Suppl 1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Clinical Trials as Topic

2005
Rabeprazole.
    Drugs, 1998, Volume: 55, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Clinical Trials as Topic

1998
Rabeprazole: a review of its use in acid-related gastrointestinal disorders.
    Drugs, 1999, Volume: 58, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Clinical Trials as Topic

1999
[Selection of antibiotics and planning of eradication for H. pylori infection].
    Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Administr

2001
Review article: rabeprazole-based therapy in Helicobacter pylori eradication.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16 Suppl 1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Clinical Trials as Topic

2002
[Dual therapy for Helicobacter pylori resistance to anti microbial agents].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Benzimidazoles; Clarithromycin; Clinical Trial

2002
[Continuation of acid suppression therapy after H. pylori eradication].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Antacids; Benzimidazoles; Clinical Trials as Topic; Enzyme

2002

Trials

34 trials available for rabeprazole and Peptic Ulcer

ArticleYear
Randomized trial comparing rabeprazole- versus lansoprazole-based Helicobacter pylori eradication regimens.
    The Kaohsiung journal of medical sciences, 2013, Volume: 29, Issue:7

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Breath Tests; Clarithromycin; Dr

2013
Similar Efficacy of Proton-Pump Inhibitors vs H2-Receptor Antagonists in Reducing Risk of Upper Gastrointestinal Bleeding or Ulcers in High-Risk Users of Low-Dose Aspirin.
    Gastroenterology, 2017, Volume: 152, Issue:1

    Topics: Aged; Aged, 80 and over; Aspirin; Double-Blind Method; Famotidine; Female; Hemoglobins; Histamine H2

2017
A postmarketing surveillance study of dexrabeprazole in the treatment of acid peptic disorders.
    Journal of the Indian Medical Association, 2009, Volume: 107, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Female; Gastroesophageal Reflux;

2009
Geranylgeranylacetone protects against diclofenac-induced gastric and small intestinal mucosal injuries in healthy subjects: a prospective randomized placebo-controlled double-blind cross-over study.
    Digestion, 2009, Volume: 80, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer

2009
The effect of cytochrome P2C19 and interleukin-1 polymorphisms on H. pylori eradication rate of 1-week triple therapy with omeprazole or rabeprazole, amoxycillin and clarithromycin in Chinese people.
    Journal of clinical pharmacy and therapeutics, 2010, Volume: 35, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Aryl

2010
Randomised clinical trial: rabeprazole plus aspirin is not inferior to rabeprazole plus clopidogrel for the healing of aspirin-related peptic ulcer.
    Alimentary pharmacology & therapeutics, 2011, Volume: 34, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aged, 80 and over; Anti-Ulcer Agents; Aspirin; Clopid

2011
Randomised clinical trial: a comparative study of 10-day sequential therapy with 7-day standard triple therapy for Helicobacter pylori infection in naïve patients.
    Alimentary pharmacology & therapeutics, 2012, Volume: 35, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer

2012
Rabeprazole reduces the recurrence risk of peptic ulcers associated with low-dose aspirin in patients with cardiovascular or cerebrovascular disease: a prospective randomized active-controlled trial.
    Journal of gastroenterology, 2012, Volume: 47, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Ulcer Agents; Aspirin; Cardiovascular Diseases;

2012
Ability of rabeprazole to prevent gastric mucosal damage from clopidogrel and low doses of aspirin depends on CYP2C19 genotype.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2012, Volume: 10, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; As

2012
Randomized open trial for comparison of proton pump inhibitors in triple therapy for Helicobacter pylori infection in relation to CYP2C19 genotype.
    Journal of gastroenterology and hepatology, 2002, Volume: 17, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Ulcer Age

2002
Patients have treatment preferences: a multicentre, double-blind, crossover study comparing rabeprazole and omeprazole.
    Current medical research and opinion, 2002, Volume: 18, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Benzimidazoles; Chi-Square

2002
[Antisecretory effect of losec and pariet in peptic ulcer therapy].
    Voenno-meditsinskii zhurnal, 2002, Volume: 323, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Benzimidazoles; Female; Gastric A

2002
Effect of different proton pump inhibitors, differences in CYP2C19 genotype and antibiotic resistance on the eradication rate of Helicobacter pylori infection by a 1-week regimen of proton pump inhibitor, amoxicillin and clarithromycin.
    Alimentary pharmacology & therapeutics, 2003, Volume: 17, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer

2003
Impact of clarithromycin resistance and CYP2C19 genetic polymorphism on treatment efficacy of Helicobacter pylori infection with lansoprazole- or rabeprazole-based triple therapy in Japan.
    European journal of gastroenterology & hepatology, 2003, Volume: 15, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer

2003
Safety and efficacy of 7-day rabeprazole- and omeprazole-based triple therapy regimens for the eradication of Helicobacter pylori in patients with documented peptic ulcer disease.
    Alimentary pharmacology & therapeutics, 2003, Volume: 17, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Be

2003
[A prospective study on rabeprazole-based triple therapy for Helicobacter pylori eradication in patients with peptic ulcer].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2003, Volume: 42, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Benz

2003
Effect of a single oral dose of rabeprazole on nocturnal acid breakthrough and nocturnal alkaline amplitude.
    World journal of gastroenterology, 2003, Volume: 9, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Alkalies; Anti-Ulcer Agents; B

2003
Comparable Helicobacter pylori eradication rates obtained with 4- and 7-day rabeprazole-based triple therapy: a preliminary study.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2003, Volume: 35, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Ulcer Ag

2003
Sequential treatment for Helicobacter pylori does not share the risk factors of triple therapy failure.
    Alimentary pharmacology & therapeutics, 2004, Feb-15, Volume: 19, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agent

2004
Comparison of rabeprazole-based four- and seven-day triple therapy and omeprazole-based seven-day triple therapy for Helicobacter pylori infection in patients with peptic ulcer.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2003, Volume: 102, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agent

2003
Efficacy of two rabeprazole/gatifloxacin-based triple therapies for Helicobacter pylori infection.
    Helicobacter, 2004, Volume: 9, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Infective Agents; Anti-Ulcer Agent

2004
The prolongation of triple therapy for Helicobacter pylori does not allow reaching therapeutic outcome of sequential scheme: a prospective, randomised study.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2004, Volume: 36, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Anti

2004
Sofalcone, a mucoprotective agent, increases the cure rate of Helicobacter pylori infection when combined with rabeprazole, amoxicillin and clarithromycin.
    World journal of gastroenterology, 2005, Mar-21, Volume: 11, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer

2005
[The clinical applications of rabeprazole either alone or combined with anti-Helicobacter pylori agents in peptic ulcer patients].
    Zhonghua nei ke za zhi, 2005, Volume: 44, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial

2005
High rate of Helicobacter pylori eradication with sequential therapy in elderly patients with peptic ulcer: a prospective controlled study.
    Alimentary pharmacology & therapeutics, 2005, Jun-15, Volume: 21, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aged, 80 and over; Amoxicillin; Benzimidazoles; Clari

2005
High rate of Helicobacter pylori eradication with sequential therapy in elderly patients with peptic ulcer: a prospective controlled study.
    Alimentary pharmacology & therapeutics, 2005, Jun-15, Volume: 21, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aged, 80 and over; Amoxicillin; Benzimidazoles; Clari

2005
High rate of Helicobacter pylori eradication with sequential therapy in elderly patients with peptic ulcer: a prospective controlled study.
    Alimentary pharmacology & therapeutics, 2005, Jun-15, Volume: 21, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aged, 80 and over; Amoxicillin; Benzimidazoles; Clari

2005
High rate of Helicobacter pylori eradication with sequential therapy in elderly patients with peptic ulcer: a prospective controlled study.
    Alimentary pharmacology & therapeutics, 2005, Jun-15, Volume: 21, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aged, 80 and over; Amoxicillin; Benzimidazoles; Clari

2005
Seven versus ten days of rabeprazole triple therapy for Helicobacter pylori eradication: a multicenter randomized trial.
    The American journal of gastroenterology, 2005, Volume: 100, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Benz

2005
Seven versus ten days of rabeprazole triple therapy for Helicobacter pylori eradication: a multicenter randomized trial.
    The American journal of gastroenterology, 2005, Volume: 100, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Benz

2005
Seven versus ten days of rabeprazole triple therapy for Helicobacter pylori eradication: a multicenter randomized trial.
    The American journal of gastroenterology, 2005, Volume: 100, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Benz

2005
Seven versus ten days of rabeprazole triple therapy for Helicobacter pylori eradication: a multicenter randomized trial.
    The American journal of gastroenterology, 2005, Volume: 100, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Benz

2005
[Five-day rabeprazole-based triple therapy for helicobacter pylori infection].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2004, Volume: 29, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Clarithromycin; Drug Administrati

2004
Effectiveness of minocycline-based triple therapy for eradication of Helicobacter pylori infection.
    Journal of gastroenterology and hepatology, 2006, Volume: 21, Issue:1 Pt 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Benz

2006
Comparison of the efficacy of rabeprazole 10 mg and omeprazole 20 mg for the healing rapidity of peptic ulcer diseases.
    Journal of gastroenterology and hepatology, 2006, Volume: 21, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; Cy

2006
Rabeprazole-based eradication therapy for Helicobacter pylori: a large-scale study in Japan.
    Alimentary pharmacology & therapeutics, 2007, May-01, Volume: 25, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clar

2007
Evaluation of three different proton pump inhibitors with amoxicillin and metronidazole in retreatment for Helicobacter pylori infection.
    Journal of clinical gastroenterology, 2008, Volume: 42, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Infective Agents; Drug Therapy, Co

2008
Safety and efficacy of rabeprazole in combination with four antibiotic regimens for the eradication of Helicobacter pylori in patients with chronic gastritis with or without peptic ulceration.
    The American journal of gastroenterology, 1998, Volume: 93, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Ulcer Agents; Benzimidazoles; Clarithromy

1998
Double-blind comparison [correction of Double-blind, placebo-controlled comparison] of rabeprazole 20 mg vs. omeprazole 20 mg in the treatment of erosive or ulcerative gastro-oesophageal reflux disease. The European Rabeprazole Study Group.
    Alimentary pharmacology & therapeutics, 1999, Volume: 13, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Benzimid

1999
A randomized open trial for comparison of proton pump inhibitors, omeprazole versus rabeprazole, in dual therapy for Helicobacter pylori infection in relation to CYP2C19 genetic polymorphism.
    Journal of gastroenterology and hepatology, 2001, Volume: 16, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Benzimidazoles

2001

Other Studies

14 other studies available for rabeprazole and Peptic Ulcer

ArticleYear
Rabeprazole Coadministration Controls Ulcer Recurrence in Patients on Low-dose Aspirin Therapy: A Multicenter Prospective Study.
    Internal medicine (Tokyo, Japan), 2023, Feb-15, Volume: 62, Issue:4

    Topics: Anti-Ulcer Agents; Aspirin; Humans; Peptic Ulcer; Prospective Studies; Rabeprazole; Ulcer

2023
Clinical factors associated with initial Helicobacter pylori eradication therapy: a retrospective study in China.
    Scientific reports, 2020, 09-21, Volume: 10, Issue:1

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Breath Tests; Clarithromycin; Dr

2020
The efficacy of moxifloxacin-containing triple therapy after standard triple, sequential, or concomitant therapy failure for Helicobacter pylori eradication in Korea.
    Gut and liver, 2014, Volume: 8, Issue:6

    Topics: Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Breath Tests; Cohort Studies; Drug Ther

2014
Stomach specific polymeric low density microballoons as a vector for extended delivery of rabeprazole and amoxicillin for treatment of peptic ulcer.
    Colloids and surfaces. B, Biointerfaces, 2016, May-01, Volume: 141

    Topics: Amoxicillin; Animals; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Delivery Systems; Drug Liberati

2016
[Comparison of Helicobacter pylori eradication rate in patients with non-ulcer dyspepsia and peptic ulcer diseases according to proton pump inhibitors].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2008, Volume: 52, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agent

2008
Correlation of CYP2C19 genetic polymorphisms with helicobacter pylori eradication in patients with cirrhosis and peptic ulcer.
    Journal of the Chinese Medical Association : JCMA, 2010, Volume: 73, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Aryl Hydrocarbon Hydroxylases; Clarithr

2010
Immunoglobulin E-mediated anaphylaxis to rabeprazole.
    Journal of investigational allergology & clinical immunology, 2010, Volume: 20, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anaphylaxis; Angioedema; Dimethindene; Drug Hypersens

2010
Proton pump inhibitors: an update.
    American family physician, 2002, Jul-15, Volume: 66, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Benzimidazoles; Drug Interactions; Esomeprazole; Gastroesop

2002
Sequential eradicating therapy: a treatment that does not discriminate Helicobacter pylori strains in patients with nonulcer dyspepsia?
    The American journal of gastroenterology, 2002, Volume: 97, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Anti

2002
A new serum antibody test kit (E plate) for evaluation of Helicobacter pylori eradication.
    Internal medicine (Tokyo, Japan), 2002, Volume: 41, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Anti

2002
[Pharmacological efficacy of bismuth tripotassium dicitrate in peptic ulcer].
    Terapevticheskii arkhiv, 2007, Volume: 79, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Antacids; Anti-Ulcer Agents; Cost-Benefit Analysis; Drug Th

2007
Effect of amoxicillin, clarithromycin, and rabeprazole, a new proton pump inhibitor, in eradication therapy for relapsing peptic ulcer diseases with Helicobacter pylori infection.
    Journal of clinical gastroenterology, 2000, Volume: 31, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Amoxicillin; Anti-Bacterial

2000
4-day triple therapy with rabeprazole, amoxicillin and clarithromycin in the eradication of Helicobacter pylori in patients with peptic ulcer disease--A pilot study.
    Zeitschrift fur Gastroenterologie, 2001, Volume: 39, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Benzimidazoles

2001
Strategy for retreatment of therapeutic failure of eradication of Helicobacter pylori infection.
    Journal of gastroenterology and hepatology, 2001, Volume: 16, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agent

2001