Page last updated: 2024-11-03

rabeprazole and Hematochezia

rabeprazole has been researched along with Hematochezia in 11 studies

Rabeprazole: A 4-(3-methoxypropoxy)-3-methylpyridinyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.

Hematochezia: The passage of bright red blood from the rectum. The blood may or may not be mixed with formed stool in the form of blood, blood clots, bloody stool or diarrhea.

Research Excerpts

ExcerptRelevanceReference
"Vonoprazan, a potassium-competitive acid blocker, is expected to improve the healing of endoscopic submucosal dissection (ESD)-induced gastric ulcers compared with proton pump inhibitors (PPIs)."9.22Vonoprazan prevents bleeding from endoscopic submucosal dissection-induced gastric ulcers. ( Hasui, T; Inaba, T; Ishida, M; Ishikawa, S; Iwamuro, M; Izumikawa, K; Kagawa, T; Kuraoka, S; Matsuura, M; Sakakihara, I; Sasaki, K; Takahashi, S; Tanaka, S; Wato, M; Yamamoto, K, 2016)
"Vonoprazan, a potassium-competitive acid blocker, is expected to improve the healing of endoscopic submucosal dissection (ESD)-induced gastric ulcers compared with proton pump inhibitors (PPIs)."5.22Vonoprazan prevents bleeding from endoscopic submucosal dissection-induced gastric ulcers. ( Hasui, T; Inaba, T; Ishida, M; Ishikawa, S; Iwamuro, M; Izumikawa, K; Kagawa, T; Kuraoka, S; Matsuura, M; Sakakihara, I; Sasaki, K; Takahashi, S; Tanaka, S; Wato, M; Yamamoto, K, 2016)
" PPIs are the mainstay therapeutic agents for prophylaxis against aspirin gastropathy and for acid-related disorders including gastroesophageal reflux disease."4.95East Asian perspective on the interaction between proton pump inhibitors and clopidogrel. ( Goh, KL; Zou, D, 2017)
"Although acid suppressants are needed to attenuate gastrointestinal bleeding (GIB) after percutaneous coronary intervention (PCI), pharmacodynamic interaction between clopidogrel and proton pump inhibitor (PPI) can increase the risk of high platelet reactivity (HPR)."1.56Influence of rabeprazole and famotidine on pharmacodynamic profile of dual antiplatelet therapy in clopidogrel-sensitive patients: The randomized, prospective, PROTECT trial. ( Ahn, JH; Bae, JS; Hwang, JY; Hwang, SJ; Jang, JY; Jeong, YH; Kang, MG; Kim, KH; Koh, JS; Kwak, CH; Park, JR; Park, Y, 2020)
" In 199 patients treated with DAT alone (control group) and 103 patients treated with rabeprazole plus DAT (rabeprazole group), we examined the incidences of GI bleeding and major adverse cardiac events (MACE) including stent thrombosis."1.36[Efficacy and safety of concomitant use of rabeprazole during dual-antiplatelet therapy with clopidogrel and aspirin after drug-eluting stent implantation: a retrospective cohort study]. ( Chubachi, H; Ikee, R; Miyasaka, Y; Saito, S; Yasu, T, 2010)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (45.45)29.6817
2010's5 (45.45)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Ahn, JH1
Park, Y1
Bae, JS1
Jang, JY1
Kim, KH1
Kang, MG1
Koh, JS1
Park, JR1
Hwang, SJ1
Kwak, CH1
Hwang, JY1
Jeong, YH1
Baeg, MK1
Choi, MG1
Moon, SJ1
Lim, CH1
Kim, JS1
Cho, YK1
Park, JM1
Lee, IS1
Kim, SW1
Choi, KY1
Hikichi, T1
Sato, M1
Watanabe, K1
Nakamura, J1
Takagi, T1
Suzuki, R1
Sugimoto, M1
Waragai, Y1
Kikuchi, H1
Konno, N1
Ohira, H1
Obara, K1
Kagawa, T1
Iwamuro, M1
Ishikawa, S1
Ishida, M1
Kuraoka, S1
Sasaki, K1
Sakakihara, I1
Izumikawa, K1
Yamamoto, K1
Takahashi, S1
Tanaka, S1
Matsuura, M1
Hasui, T1
Wato, M1
Inaba, T1
Zou, D1
Goh, KL1
Yasu, T1
Ikee, R1
Miyasaka, Y1
Chubachi, H1
Saito, S1
Hata, M2
Shiono, M2
Sekino, H2
Furukawa, H2
Sezai, A2
Iida, M2
Yoshitake, I2
Hattori, T2
Wakui, S2
Soeda, M1
Taoka, M2
Negishi, N2
Sezai, Y2
Gon, S1
Irie, Y1
Takahashi, M1
Sung, HY1
Kim, JI1
Park, YB1
Cheung, DY1
Cho, SH1
Park, SH1
Han, JY1
Kim, JK1
Barada, K1
Karrowni, W1
Abdallah, M1
Shamseddeen, W1
Sharara, AI1
Dakik, HA1

Reviews

1 review available for rabeprazole and Hematochezia

ArticleYear
East Asian perspective on the interaction between proton pump inhibitors and clopidogrel.
    Journal of gastroenterology and hepatology, 2017, Volume: 32, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anticoagulants; Asia, Eastern; Asian People; Aspirin; Clopi

2017

Trials

4 trials available for rabeprazole and Hematochezia

ArticleYear
Preprocedural rabeprazole treatment before endoscopic submucosal dissection for gastric neoplasms.
    Digestive diseases and sciences, 2014, Volume: 59, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Dissection; Female; Gastric Mucosa; Gastrointestinal

2014
Oral rabeprazole administration on a procedure day suppresses bleeding after endoscopic submucosal dissection for gastric neoplasms.
    Fukushima journal of medical science, 2014, Volume: 60, Issue:1

    Topics: Adenocarcinoma; Adenoma; Administration, Oral; Aged; Aged, 80 and over; Female; Gastrointestinal Hem

2014
Vonoprazan prevents bleeding from endoscopic submucosal dissection-induced gastric ulcers.
    Alimentary pharmacology & therapeutics, 2016, Volume: 44, Issue:6

    Topics: Adenoma; Aged; Aged, 80 and over; Endoscopic Mucosal Resection; Female; Gastrointestinal Hemorrhage;

2016
Prospective randomized trial for optimal prophylactic treatment of the upper gastrointestinal complications after open heart surgery.
    Circulation journal : official journal of the Japanese Circulation Society, 2005, Volume: 69, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Cardiac Surgical Procedu

2005

Other Studies

6 other studies available for rabeprazole and Hematochezia

ArticleYear
Influence of rabeprazole and famotidine on pharmacodynamic profile of dual antiplatelet therapy in clopidogrel-sensitive patients: The randomized, prospective, PROTECT trial.
    Platelets, 2020, Volume: 31, Issue:3

    Topics: Aged; Clopidogrel; Drug Interactions; Famotidine; Female; Gastrointestinal Hemorrhage; Humans; Male;

2020
[Efficacy and safety of concomitant use of rabeprazole during dual-antiplatelet therapy with clopidogrel and aspirin after drug-eluting stent implantation: a retrospective cohort study].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2010, Volume: 130, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Aryl Hydrocarbon Hydroxylases; Aspirin; Clopidogrel;

2010
Efficacy of a proton pump inhibitor given in the early postoperative period to relieve symptoms of hiatal hernia after open heart surgery.
    Surgery today, 2006, Volume: 36, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Benzimidazoles; Cardiac Sur

2006
Effects of rabeprazole or famotidine during cardiac surgery on perioperative gastric and esophageal pH readings.
    The Japanese journal of thoracic and cardiovascular surgery : official publication of the Japanese Association for Thoracic Surgery = Nihon Kyobu Geka Gakkai zasshi, 2006, Volume: 54, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Ulcer Agents; Benzimidazoles;

2006
The papilla of Vater just below the pylorus presenting as recurrent duodenal ulcer bleeding.
    Internal medicine (Tokyo, Japan), 2007, Volume: 46, Issue:22

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Bile; Bile Ducts; Duodenal Ulcer;

2007
Upper gastrointestinal bleeding in patients with acute coronary syndromes: clinical predictors and prophylactic role of proton pump inhibitors.
    Journal of clinical gastroenterology, 2008, Volume: 42, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Coronary Syndrome; Aged; Female; Fibrinolytic Agents;

2008