Page last updated: 2024-11-03

rabeprazole and Gastric Ulcer

rabeprazole has been researched along with Gastric Ulcer in 57 studies

Rabeprazole: A 4-(3-methoxypropoxy)-3-methylpyridinyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.

Research Excerpts

ExcerptRelevanceReference
"According to this trial, ilaprazole and rabeprazole showed no significant difference in the healing of artificial gastric ulcers."9.30Effect of ilaprazole on the healing of endoscopic submucosal dissection-induced gastric ulcer: randomized-controlled, multicenter study. ( Baik, GH; Bang, CS; Choi, MH; Jang, HJ; Kae, SH; Kim, HY; Park, SW; Seo, SI; Shin, SP; Shin, WG; Yang, YJ, 2019)
"Patients in the vonoprazan group (n = 75) were prospectively enrolled, whereas patients in the PPI group (n = 150) were selected for a 2:1 matched historical control cohort according to baseline characteristics including gastric ulcer size immediately following ESD, age, sex and status of Helicobacter pylori infection."9.22Vonoprazan prevents bleeding from endoscopic submucosal dissection-induced gastric ulcers. ( Hasui, T; Inaba, T; Ishida, M; Ishikawa, S; Iwamuro, M; Izumikawa, K; Kagawa, T; Kuraoka, S; Matsuura, M; Sakakihara, I; Sasaki, K; Takahashi, S; Tanaka, S; Wato, M; Yamamoto, K, 2016)
"To evaluate the effect of a single dose of rebeprazole (RAB) versus omeprazole (OME) on acid suppression and symptom relief in patients with gastric ulcer."9.11[The effect of rabeprazole on gastric pH in patients with gastric ulcer]. ( Ke, MY, 2004)
"In this randomized, double-blind, multicentre study, conducted at 25 European sites, rabeprazole and omeprazole were compared in patients with active gastric ulcers."9.08Comparison of rabeprazole 20 mg vs. omeprazole 20 mg in the treatment of active gastric ulcer--a European multicentre study. The European Rabeprazole Study Group. ( Beker, JA; Bell, NE; Dekkers, CP; Gabryelewicz, A; Humphries, TJ; Thjodleifsson, B, 1998)
"Rabeprazole, a new proton pump inhibitor, was studied in patients with acid-peptic-related diseases (duodenal ulcer, gastric ulcer, GERD) in three placebo-controlled, double-blind, randomized clinical trials."9.08Rabeprazole in treatment of acid peptic diseases: results of three placebo-controlled dose-response clinical trials in duodenal ulcer, gastric ulcer, and gastroesophageal reflux disease (GERD). The Rabeprazole Study Group. ( Bassion, S; Cloud, ML; Enas, N; Humphries, TJ, 1998)
"We compared the PGE(2) and LTB(4) levels and the expression levels of cyclooxygenase (COX)-1 and COX-2 mRNA in the gastric mucosa in gastric ulcer patients between the group treated for 8 weeks with a PPI, rabeprazole (PPI group; n=5), and the group treated for 8 weeks with an H(2) blocker, ranitidine (H(2) blocker group; n=6), as well as in nonulcer subjects (control group; n=5)."7.74Gastric mucosal levels of prostaglandins and leukotrienes in patients with gastric ulcer after treatment with rabeprazole in comparison to treatment with ranitidine. ( Fujiwara, S; Horie, T; Ishikawa, M; Ito, S; Iuchi, A; Okazaki, M; Shimizu, I; Shiraishi, T; Yamamoto, H, 2007)
"According to this trial, ilaprazole and rabeprazole showed no significant difference in the healing of artificial gastric ulcers."5.30Effect of ilaprazole on the healing of endoscopic submucosal dissection-induced gastric ulcer: randomized-controlled, multicenter study. ( Baik, GH; Bang, CS; Choi, MH; Jang, HJ; Kae, SH; Kim, HY; Park, SW; Seo, SI; Shin, SP; Shin, WG; Yang, YJ, 2019)
"In this prospective, randomized, multicenter, open-label, and comparative study, patients who had undergone ESD for EGC or gastric adenoma were randomized into groups receiving either rabeprazole monotherapy (10 mg/day, n=64) or a combination of rabeprazole plus rebamipide (300 mg/day, n=66)."5.22Limited Effect of Rebamipide in Addition to Proton Pump Inhibitor (PPI) in the Treatment of Post-Endoscopic Submucosal Dissection Gastric Ulcers: A Randomized Controlled Trial Comparing PPI Plus Rebamipide Combination Therapy with PPI Monotherapy. ( Akahoshi, K; Akiho, H; Aso, A; Harada, N; Iboshi, Y; Ihara, E; Iwasa, T; Nakamura, K; Nakamura, N; Ochiai, T; Ogino, H; Takayanagi, R, 2016)
"Patients in the vonoprazan group (n = 75) were prospectively enrolled, whereas patients in the PPI group (n = 150) were selected for a 2:1 matched historical control cohort according to baseline characteristics including gastric ulcer size immediately following ESD, age, sex and status of Helicobacter pylori infection."5.22Vonoprazan prevents bleeding from endoscopic submucosal dissection-induced gastric ulcers. ( Hasui, T; Inaba, T; Ishida, M; Ishikawa, S; Iwamuro, M; Izumikawa, K; Kagawa, T; Kuraoka, S; Matsuura, M; Sakakihara, I; Sasaki, K; Takahashi, S; Tanaka, S; Wato, M; Yamamoto, K, 2016)
"To evaluate the effect of a single dose of rebeprazole (RAB) versus omeprazole (OME) on acid suppression and symptom relief in patients with gastric ulcer."5.11[The effect of rabeprazole on gastric pH in patients with gastric ulcer]. ( Ke, MY, 2004)
"A total of 102 Helicobacter pylori-positive patients with gastric ulcer were randomly allocated to three groups: rabeprazole 10 mg (RAC10), rabeprazole 20 mg (RAC20) or rabeprazole 40 mg (RAC40) plus amoxicillin 750 mg and clarithromycin 200 mg twice daily for 7 days."5.09Efficacy of triple therapy with rabeprazole for Helicobacter pylori infection and CYP2C19 genetic polymorphism. ( Asaka, M; Hige, S; Hokari, K; Ishizuka, J; Kagaya, H; Kato, M; Komatsu, Y; Kudo, M; Miyagishima, T; Mizushima, T; Nishikawa, K; Saito, M; Sugiyama, T; Takeda, H, 2001)
"In this randomized, double-blind, multicentre study, conducted at 25 European sites, rabeprazole and omeprazole were compared in patients with active gastric ulcers."5.08Comparison of rabeprazole 20 mg vs. omeprazole 20 mg in the treatment of active gastric ulcer--a European multicentre study. The European Rabeprazole Study Group. ( Beker, JA; Bell, NE; Dekkers, CP; Gabryelewicz, A; Humphries, TJ; Thjodleifsson, B, 1998)
"Rabeprazole, a new proton pump inhibitor, was studied in patients with acid-peptic-related diseases (duodenal ulcer, gastric ulcer, GERD) in three placebo-controlled, double-blind, randomized clinical trials."5.08Rabeprazole in treatment of acid peptic diseases: results of three placebo-controlled dose-response clinical trials in duodenal ulcer, gastric ulcer, and gastroesophageal reflux disease (GERD). The Rabeprazole Study Group. ( Bassion, S; Cloud, ML; Enas, N; Humphries, TJ, 1998)
" In 8-week studies, among patients with gastro-oesophageal reflux disease (GORD), rabeprazole 20 mg/day or 10mg twice daily was as effective as omeprazole and superior to ranitidine in the healing of GORD."4.81Rabeprazole: an update of its use in acid-related disorders. ( Carswell, CI; Goa, KL, 2001)
" To evaluate the efficacy of the new PPI rabeprazole, 12 controlled clinical trials were conducted worldwide-three for each indication (erosive or ulcerative GERD healing, long-term GERD healing maintenance, duodenal ulcer healing, and gastric ulcer healing)."4.81Efficacy of rabeprazole once daily for acid-related disorders. ( Bardhan, KD; Barth, J; Lanza, F; Niecestro, R; Perdomo, C, 2001)
" Healing rates for rabeprazole were equivalent to omeprazole in all indications, and superior (GORD healing and duodenal ulcer healing) or equivalent (gastric ulcer healing) to the histamine 2-receptor antagonist ranitidine."4.80The benefit/risk profile of rabeprazole, a new proton-pump inhibitor. ( Barth, J; Johnson, D; Jokubaitis, L; Perdomo, C, 2000)
"A retrospective study was conducted among 64 patients with gastric ulcers of spleen deficiency and dampness heat admitted to our hospital from September 2019 to May 2020, and they were divided at a ratio of 1 : 1 into an observation group (rabeprazole sodium enteric-coated capsules plus Erzhu Yiren Decoction) and a control group (rabeprazole sodium enteric-coated capsules) based on different treatment methods."4.12A Retrospective Trial Exploring Erzhu Yiren Decoction in Gastric Ulcer with Spleen Deficiency and Dampness-Heat. ( Shan, Z; Zhang, T, 2022)
"We compared the PGE(2) and LTB(4) levels and the expression levels of cyclooxygenase (COX)-1 and COX-2 mRNA in the gastric mucosa in gastric ulcer patients between the group treated for 8 weeks with a PPI, rabeprazole (PPI group; n=5), and the group treated for 8 weeks with an H(2) blocker, ranitidine (H(2) blocker group; n=6), as well as in nonulcer subjects (control group; n=5)."3.74Gastric mucosal levels of prostaglandins and leukotrienes in patients with gastric ulcer after treatment with rabeprazole in comparison to treatment with ranitidine. ( Fujiwara, S; Horie, T; Ishikawa, M; Ito, S; Iuchi, A; Okazaki, M; Shimizu, I; Shiraishi, T; Yamamoto, H, 2007)
"Patients with gastric ulcers were allocated to an untreated control group, consisting of patients with active ulcers (GA), healing ulcers (GH), and ulcer scars (GS) or a PPI group (P; given rabeprazole at 20 mg/day), or an H2-blocker group (H; given nizatidine at 800 mg/day)."3.73Effects of antisecretory agents on angiogenesis during healing of gastric ulcers. ( Akimoto, M; Hashimoto, H; Maeda, A; Shigemoto, M; Yamashita, K, 2005)
" We examined the roles of TNF-alpha and dynamics of chemokine expression in gastric ulceration including ulcer recurrence and indomethacin-induced injury."3.72Monocyte chemotactic protein-1 regulates leukocyte recruitment during gastric ulcer recurrence induced by tumor necrosis factor-alpha. ( Arakawa, T; Fujiwara, Y; Hamaguchi, M; Higuchi, K; Matsumoto, T; Shiba, M; Tominaga, K; Watanabe, T, 2004)
" pylori infected patients with gastric ulcer and duodenal ulcer completed the triple therapy with 10 mg of rabeprazole b."3.72Efficacy of triple therapy with rabeprazole for Helicobacter pylori infection in relation to CYP2C19 genotype. ( Bae, JS; Jung, HS; Kim, HJ; Lee, JK; Lee, SB; Park, SJ; Park, SM; Ryu, JK, 2003)
" The aim of the present study was to investigate the pathogenesis of these gastric ulcers and to examine the effects of two antiulcer drugs; a proton pump inhibitor (2{[4-(3-methoxypropoxy)-3-methylpyridine-2-yl]methyl-sulfinyl}-1H -benzimidazole sodium salt, rabeprazole) and a mucosal protective drug (geranylgeranylacetone, GGA), on the gastric ulcers."3.70Bile reflux due to disturbed gastric movement is a cause of spontaneous gastric ulcer in W/Wv mice. ( Azuma, T; Dojyo, M; Ito, S; Ito, Y; Kato, T; Kohli, Y; Kuriyama, M; Miyaji, H; Suto, H; Yamazaki, Y, 1999)
"This study was designed to clarify effects of proton pump inhibitors, E-3810(2-([4-(3-methoxypropoxy)-3methylpyridine-2-yl]methyl- sulfinyl)-1H-benzimidazol sodium salt) and omeprazole (CAS 73590-58-6), on water immersion stress-induced gastric ulcers in relation to mucosal prostaglandins (PGs) and leukotrienes (LTs)."3.68Effects of two benzimidazoles as proton pump inhibitors on water immersion stress-induced gastric ulcers in rats. ( Goto, H; Hoshino, H; Kuroiwa, M; Nakazawa, S; Ohara, A; Ozawa, T; Sugiyama, S; Tsukamoto, Y, 1991)
"Rabeprazole prevents the recurrence of peptic ulcers with no evidence of a major dose-response effect in subjects on low-dose aspirin therapy."2.79Randomised clinical trial: prevention of recurrence of peptic ulcers by rabeprazole in patients taking low-dose aspirin. ( Arakawa, T; Fujimoto, K; Fujishiro, M; Higuchi, K; Iwakiri, R; Kato, M; Kinoshita, Y; Nakagawa, H; Ogawa, H; Okada, Y; Sanomura, M; Sugisaki, N; Takeuchi, T; Watanabe, T; Yamauchi, M, 2014)
"Although endoscopic submucosal dissection (ESD)-induced ulcers heal faster and recur less often than non-iatrogenic gastric ulcers, the optimal dosage and duration of proton pump inhibitor treatment for ESD-induced ulcers remain unclear."2.78Half-dose rabeprazole has an equal efficacy to standard-dose rabeprazole on endoscopic submucosal dissection-induced ulcer. ( Hong, JH; Jo, KW; Kim, BR; Kim, HS; Kim, JW; Park, HJ; Park, SY, 2013)
"pantoprazole was 6."2.74Comparison of p.o. or i.v. proton pump inhibitors on 72-h intragastric pH in bleeding peptic ulcer. ( Gulzar, GM; Javid, G; Khan, BA; Khan, MA; Shah, AH; Sodhi, JS; U-Saif, R; Yatoo, GN; Zargar, SA, 2009)
"Rabeprazole is a new proton pump inhibitor with more potent acid suppressive and anti-Helicobacter effects."2.70Rabeprazole-based 3-day and 7-day triple therapy vs. omeprazole-based 7-day triple therapy for the treatment of Helicobacter pylori infection. ( Fung, FM; Hu, WH; Hui, CK; Hung, WK; Lai, KC; Lam, SK; Lau, P; Li, KF; Szeto, ML; Tong, TS; Wong, BC; Wong, WM; Yee, YK; Yip, AW; Yuen, MF, 2001)
"Rabeprazole is a new PPI with demonstrated efficacy in both the acute and maintenance treatment of erosive GERD."2.69Rabeprazole versus omeprazole in preventing relapse of erosive or ulcerative gastroesophageal reflux disease: a double-blind, multicenter, European trial. The European Rabeprazole Study Group. ( Beker, JA; Bjaaland, T; Dekkers, C; Finnegan, V; Humphries, TJ; Thjodleifsson, B, 2000)
"Twenty-four healthy male volunteers were studied on the 7th day of morning dosing with either placebo or rabeprazole 10, 20 or 40 mg in a crossover fashion."2.69A placebo-controlled study to assess the effects of 7-day dosing with 10, 20 and 40 mg rabeprazole on 24-h intragastric acidity and plasma gastrin in healthy male subjects. ( Blanshard, C; Millson, C; Pounder, RE; Sercombe, J; Williams, MP, 2000)
") occurring after the start of rabeprazole treatment were handled as adverse events."1.35Efficacy and safety of rabeprazole in non-steroidal anti-inflammatory drug-induced ulcer in Japan. ( Mizokami, Y, 2009)
"Group 1 comprised 47 patients with GERD and group 2 49 patients with gastric and duodenal UD."1.35[Combined therapy of acid-dependent gastrointestinal disorders with the use of antacidic drug Relcer]. ( Andreev, NG; Beliantseva, EV; Golubev, NN; Maev, IV; Odintsova, AN; Samsonov, AA, 2009)
"Rabeprazole is a proton pump inhibitor (PPI) presenting a very advantageous pharmacodynamic and pharmacokinetic profile over older PPIs."1.35Rabeprazole: a second-generation proton pump inhibitor in the treatment of acid-related disease. ( Marelli, S; Pace, F; Pallotta, S, 2008)
"Pretreatment with indomethacin did not influence the cytoprotective effect of rabeprazole."1.31Cytoprotective effect of rabeprazole against ethanol-induced gastric mucosal damage: possible involvement of nitric oxide. ( Arakawa, T; Fujiwara, Y; Higuchi, K; Tominaga, K; Watanabe, T, 2000)
"Rabeprazole has a favourable profile with rapid action and good safety."1.31[Pharma-clinics medication of the month. Rabeprazole (Pariet)]. ( Louis, E, 2002)

Research

Studies (57)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (12.28)18.2507
2000's34 (59.65)29.6817
2010's15 (26.32)24.3611
2020's1 (1.75)2.80

Authors

AuthorsStudies
Zhang, T1
Shan, Z1
Yamasaki, A1
Yoshio, T1
Muramatsu, Y1
Horiuchi, Y1
Ishiyama, A1
Hirasawa, T1
Tsuchida, T1
Sasaki, Y1
Fujisaki, J1
Bang, CS1
Shin, WG1
Seo, SI1
Choi, MH1
Jang, HJ1
Park, SW1
Kae, SH1
Yang, YJ1
Shin, SP1
Baik, GH1
Kim, HY1
Iwakiri, R2
Higuchi, K3
Kato, M2
Fujishiro, M2
Kinoshita, Y1
Watanabe, T3
Takeuchi, T1
Yamauchi, M1
Sanomura, M1
Nakagawa, H1
Sugisaki, N1
Okada, Y1
Ogawa, H1
Arakawa, T3
Fujimoto, K2
Howden, CW1
Lee, HJ1
Kim, JI2
Lee, JS1
Jun, EJ1
Oh, JH1
Cheung, DY2
Chung, WC1
Kim, BW1
Kim, SS1
Nakamura, K1
Ihara, E1
Akiho, H1
Akahoshi, K1
Harada, N1
Ochiai, T1
Nakamura, N1
Ogino, H1
Iwasa, T1
Aso, A1
Iboshi, Y1
Takayanagi, R1
Kagawa, T1
Iwamuro, M1
Ishikawa, S1
Ishida, M1
Kuraoka, S1
Sasaki, K1
Sakakihara, I1
Izumikawa, K1
Yamamoto, K1
Takahashi, S1
Tanaka, S1
Matsuura, M1
Hasui, T1
Wato, M1
Inaba, T1
Pallotta, S1
Pace, F1
Marelli, S1
Li, Y1
Wang, XY1
Shen, SR1
Pellicano, R1
Osipenko, MF1
Konstantinov, VI1
Moiseenko, EE1
Bikbulatova, EA1
Nishino, M1
Sugimoto, M1
Kodaira, C1
Yamade, M1
Shirai, N1
Ikuma, M1
Tanaka, T1
Sugimura, H1
Hishida, A1
Furuta, T1
Tan, VP1
Wong, BC2
Javid, G1
Zargar, SA1
U-Saif, R1
Khan, BA1
Yatoo, GN1
Shah, AH1
Gulzar, GM1
Sodhi, JS1
Khan, MA1
Maev, IV1
Samsonov, AA1
Beliantseva, EV1
Golubev, NN1
Odintsova, AN1
Andreev, NG1
Mizokami, Y1
Fujiwara, S2
Morita, Y1
Toyonaga, T1
Kawakami, F1
Itoh, T1
Yoshida, M1
Kutsumi, H1
Azuma, T2
Niimi, K1
Goto, O1
Kodashima, S1
Minatsuki, C1
Hirayama, I1
Mochizuki, S1
Ono, S1
Yamamichi, N1
Kakushima, N1
Ichinose, M1
Koike, K1
Choi, HS1
Chun, HJ1
Park, SH2
Keum, B1
Seo, YS1
Kim, YS1
Jeen, YT1
Um, SH1
Lee, HS1
Kim, CD1
Ryu, HS1
Murata, T1
Kawashima, M1
Terayama, Y1
Okamura, Y1
Takeno, S1
Takahashi, Y1
Moroga, T1
Yamashita, S1
Kawahara, K1
Park, HJ1
Kim, HS1
Kim, BR1
Park, SY1
Hong, JH1
Jo, KW1
Kim, JW1
Vasil'ev, IuV1
Kas'ianenko, VI1
Minushkin, ON1
Zverkov, IV1
Aronova, OV1
Shuleshova, AG1
Murakami, K1
Sato, R1
Okimoto, T1
Nasu, M1
Fujioka, T1
Kodama, M1
Kagawa, J1
Sato, S1
Abe, H1
Arita, T1
Sorba, G1
Galli, U1
Cena, C1
Fruttero, R1
Gasco, A1
Morini, G1
Adami, M1
Coruzzi, G1
Brenciaglia, MI1
Dubini, F1
Lee, SB1
Park, SJ1
Ryu, JK1
Lee, JK1
Kim, HJ1
Bae, JS1
Jung, HS1
Park, SM1
Hamaguchi, M1
Shiba, M1
Tominaga, K2
Fujiwara, Y2
Matsumoto, T1
Kotaira, J1
Ke, MY1
Akimoto, M1
Hashimoto, H1
Shigemoto, M1
Maeda, A1
Yamashita, K1
Ando, T2
Kato, H1
Sugimoto, N1
Nagao, Y1
Seto, N1
Hongo, H1
Kajikawa, H1
Isozaki, Y1
Shimozawa, M1
Naito, Y2
Yoshida, N2
Ishizaki, T1
Yoshikawa, T2
Arisawa, T2
Shibata, T1
Kamiya, Y1
Nagasaka, M1
Nakamura, M2
Fujita, H1
Hasegawa, S1
Harata, M1
Mizuno, T1
Tahara, T1
Ohta, Y1
Nakano, H1
Okazaki, M1
Shimizu, I1
Ishikawa, M1
Yamamoto, H1
Shiraishi, T1
Horie, T1
Iuchi, A1
Ito, S2
Cho, SH1
Han, JY1
Kim, JK1
Han, SW1
Choi, KY1
Chung, IS1
Ishikawa, T1
Kokura, S1
Takimoto, T1
Ido, K1
Taniguchi, Y1
Satoh, K1
Saifuku, K1
Kihira, K1
Yoshida, Y1
Kimura, K1
Cloud, ML1
Enas, N1
Humphries, TJ3
Bassion, S1
Dekkers, CP1
Beker, JA2
Thjodleifsson, B2
Gabryelewicz, A1
Bell, NE1
Dojyo, M1
Yamazaki, Y1
Miyaji, H1
Ito, Y1
Suto, H1
Kuriyama, M1
Kato, T1
Kohli, Y1
Dekkers, C1
Bjaaland, T1
Finnegan, V1
Williams, MP1
Blanshard, C1
Millson, C1
Sercombe, J1
Pounder, RE1
Johnson, D1
Perdomo, C2
Barth, J2
Jokubaitis, L1
Lanza, F1
Bardhan, KD1
Niecestro, R1
Bardou, M1
Hokari, K1
Sugiyama, T1
Saito, M1
Miyagishima, T1
Kudo, M1
Nishikawa, K1
Ishizuka, J1
Komatsu, Y1
Mizushima, T1
Kagaya, H1
Hige, S1
Takeda, H1
Asaka, M1
Herszényi, L1
Tulassay, Z1
Wong, WM1
Yee, YK1
Hung, WK1
Yip, AW1
Szeto, ML1
Li, KF1
Lau, P1
Fung, FM1
Tong, TS1
Lai, KC1
Hu, WH1
Yuen, MF1
Hui, CK1
Lam, SK1
Carswell, CI1
Goa, KL1
Suzuki, M1
Suzuki, H1
Kitahora, T1
Miyazawa, M1
Nagahashi, S1
Suzuki, K1
Ishii, H1
Louis, E1
Suzuki, T1
Tsukamoto, Y2
Goto, H2
Hase, S1
Asai, J1
Sugiyama, S1
Kuroiwa, M1
Ohara, A1
Hoshino, H1
Nakazawa, S1
Ozawa, T1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of Ilaprazole 20mg on Ulcer Healing Rate and Prevention of Gastrointestinal Bleeding in the Patients Undergone Endoscopic Submucosal Dissection(ESD) for Gastric Adenoma or Early Gastric Cancer.[NCT02638584]Phase 4176 participants (Actual)Interventional2015-12-31Completed
Evaluation of the Efficacy of Concomitant Therapy for Eradication of Helicobacter Pylori[NCT01922765]Phase 4540 participants (Anticipated)Interventional2013-08-31Recruiting
The Phase 2 Study of FP-10, the Food Ingredient Derived From Milk Casein, on the Eradication Rates of Helicobacter Pylori by a Triple Therapy With Lansoprazole, Amoxicillin, and Clarithromycin[NCT00281047]Phase 2/Phase 3138 participants Interventional2006-01-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

6 reviews available for rabeprazole and Gastric Ulcer

ArticleYear
[Proton pump inhibitors, a family of drugs in continuous expansion].
    Minerva gastroenterologica e dietologica, 2000, Volume: 46, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Inflammatory Agents, Non-Steroidal; Barrett E

2000
The benefit/risk profile of rabeprazole, a new proton-pump inhibitor.
    European journal of gastroenterology & hepatology, 2000, Volume: 12, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Benzimidazoles; Controlled Clinical Trials as Topic; Duoden

2000
Efficacy of rabeprazole once daily for acid-related disorders.
    Digestive diseases and sciences, 2001, Volume: 46, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Anti-Ulcer Agents; Benzimidazole

2001
[H2 receptor antagonists and proton pump inhibitors: principles and rules of use].
    La Revue du praticien, 2001, Apr-15, Volume: 51, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Age Factors; Aged; Anti-Ulcer Agents; Benzimidazoles; Child

2001
[Comparative study of proton pump inhibitors].
    Orvosi hetilap, 2001, Sep-09, Volume: 142, Issue:36

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Bacterial Agents; Anti-Ulcer Agents; Benzimidazoles; C

2001
Rabeprazole: an update of its use in acid-related disorders.
    Drugs, 2001, Volume: 61, Issue:15

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; Benzimida

2001

Trials

25 trials available for rabeprazole and Gastric Ulcer

ArticleYear
Effect of ilaprazole on the healing of endoscopic submucosal dissection-induced gastric ulcer: randomized-controlled, multicenter study.
    Surgical endoscopy, 2019, Volume: 33, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Anti-Ulcer Agents; Endoscopic Mucosal Resection; Fema

2019
Randomised clinical trial: prevention of recurrence of peptic ulcers by rabeprazole in patients taking low-dose aspirin.
    Alimentary pharmacology & therapeutics, 2014, Volume: 40, Issue:7

    Topics: Aged; Anti-Ulcer Agents; Aspirin; Double-Blind Method; Duodenal Ulcer; Female; Fibrinolytic Agents;

2014
Concomitant therapy achieved the best eradication rate for Helicobacter pylori among various treatment strategies.
    World journal of gastroenterology, 2015, Jan-07, Volume: 21, Issue:1

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Breath Tests; Clarithromycin; Drug Therapy, Combina

2015
Limited Effect of Rebamipide in Addition to Proton Pump Inhibitor (PPI) in the Treatment of Post-Endoscopic Submucosal Dissection Gastric Ulcers: A Randomized Controlled Trial Comparing PPI Plus Rebamipide Combination Therapy with PPI Monotherapy.
    Gut and liver, 2016, Nov-15, Volume: 10, Issue:6

    Topics: Adenoma; Aged; Alanine; Anti-Ulcer Agents; Drug Therapy, Combination; Endoscopic Mucosal Resection;

2016
Vonoprazan prevents bleeding from endoscopic submucosal dissection-induced gastric ulcers.
    Alimentary pharmacology & therapeutics, 2016, Volume: 44, Issue:6

    Topics: Adenoma; Aged; Aged, 80 and over; Endoscopic Mucosal Resection; Female; Gastrointestinal Hemorrhage;

2016
[Efficacy of 4 kinds of triple strategy for Helicobacter pylori eradication].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2008, Volume: 33, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer

2008
Relationship between low-dose aspirin-induced gastric mucosal injury and intragastric pH in healthy volunteers.
    Digestive diseases and sciences, 2010, Volume: 55, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon H

2010
Comparison of p.o. or i.v. proton pump inhibitors on 72-h intragastric pH in bleeding peptic ulcer.
    Journal of gastroenterology and hepatology, 2009, Volume: 24, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adolescent; Adult; Drug Administratio

2009
A randomized controlled trial of rebamipide plus rabeprazole for the healing of artificial ulcers after endoscopic submucosal dissection.
    Journal of gastroenterology, 2011, Volume: 46, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Alanine; Anti-Ulcer Agents; Disease Progression; Drug

2011
Comparison of sequential and 7-, 10-, 14-d triple therapy for Helicobacter pylori infection.
    World journal of gastroenterology, 2012, May-21, Volume: 18, Issue:19

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Alkylating Agents; Amoxicillin; Anti-Bacterial Agents; Anti

2012
Half-dose rabeprazole has an equal efficacy to standard-dose rabeprazole on endoscopic submucosal dissection-induced ulcer.
    Digestive diseases and sciences, 2013, Volume: 58, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Double-Blind Method; Female; Gastroscopy; Humans; Mal

2013
Eradication rates of clarithromycin-resistant Helicobacter pylori using either rabeprazole or lansoprazole plus amoxicillin and clarithromycin.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:11

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agent

2002
[Prospective comparative study on protective effect of the proton pump inhibitor and the prostaglandin analog on H. pylori-negative gastric mucosa of healthy subjects against low-dose aspirin].
    [Hokkaido igaku zasshi] The Hokkaido journal of medical science, 2004, Volume: 79, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Aspirin; Benzimidazoles; Enzyme I

2004
[The effect of rabeprazole on gastric pH in patients with gastric ulcer].
    Zhonghua nei ke za zhi, 2004, Volume: 43, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Benzimidazoles; Double-Blind Meth

2004
A comparative study on endoscopic ulcer healing of omeprazole versus rabeprazole with respect to CYP2C19 genotypic differences.
    Digestive diseases and sciences, 2005, Volume: 50, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylases; Be

2005
Oral proton pump inhibitors are as effective as endoscopic treatment for bleeding peptic ulcer: a prospective, randomized, controlled trial.
    Digestive diseases and sciences, 2007, Volume: 52, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Aged; Duodenal Ulcer; Endoscop

2007
Endoscopic analysis of gastric ulcer after one week's treatment with omeprazole and rabeprazole in relation to CYP2C19 genotype.
    Digestive diseases and sciences, 2008, Volume: 53, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Aryl Hydrocarbon Hydroxylas

2008
Efficacy of lansoprazole in eradication of Helicobacter pylori.
    Journal of clinical gastroenterology, 1995, Volume: 20 Suppl 2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Benzimidaz

1995
Rabeprazole in treatment of acid peptic diseases: results of three placebo-controlled dose-response clinical trials in duodenal ulcer, gastric ulcer, and gastroesophageal reflux disease (GERD). The Rabeprazole Study Group.
    Digestive diseases and sciences, 1998, Volume: 43, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Breath Tests; Dose-Respo

1998
Comparison of rabeprazole 20 mg vs. omeprazole 20 mg in the treatment of active gastric ulcer--a European multicentre study. The European Rabeprazole Study Group.
    Alimentary pharmacology & therapeutics, 1998, Volume: 12, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Ulcer Agents; Benzimidazoles;

1998
Rabeprazole versus omeprazole in preventing relapse of erosive or ulcerative gastroesophageal reflux disease: a double-blind, multicenter, European trial. The European Rabeprazole Study Group.
    Digestive diseases and sciences, 2000, Volume: 45, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Ulcer Agents; Benzimidazoles; Dose-Respon

2000
A placebo-controlled study to assess the effects of 7-day dosing with 10, 20 and 40 mg rabeprazole on 24-h intragastric acidity and plasma gastrin in healthy male subjects.
    Alimentary pharmacology & therapeutics, 2000, Volume: 14, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Ulcer Agents; Benzimidazoles; Cross-Over Studie

2000
Efficacy of triple therapy with rabeprazole for Helicobacter pylori infection and CYP2C19 genetic polymorphism.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Aryl

2001
Rabeprazole-based 3-day and 7-day triple therapy vs. omeprazole-based 7-day triple therapy for the treatment of Helicobacter pylori infection.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:12

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Benzimid

2001
Treatment with a proton pump inhibitor promotes corpus gastritis in patients with Helicobacter pylori-infected antrum-predominant gastritis.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Adult; Aged; Benzimidazoles; Biopsy;

2002

Other Studies

26 other studies available for rabeprazole and Gastric Ulcer

ArticleYear
A Retrospective Trial Exploring Erzhu Yiren Decoction in Gastric Ulcer with Spleen Deficiency and Dampness-Heat.
    BioMed research international, 2022, Volume: 2022

    Topics: Capsules; Dinoprostone; Epidermal Growth Factor; Hot Temperature; Humans; Rabeprazole; Retrospective

2022
Vonoprazan is Superior to Rabeprazole for Healing Endoscopic Submucosal Dissection: Induced Ulcers.
    Digestion, 2018, Volume: 97, Issue:2

    Topics: Administration, Intravenous; Adult; Aged; Aged, 80 and over; Drug Substitution; Endoscopic Mucosal R

2018
PPI vs. teprenone in preventing recurrence of ulcers during low-dose aspirin - authors' reply.
    Alimentary pharmacology & therapeutics, 2014, Volume: 40, Issue:11-12

    Topics: Anti-Ulcer Agents; Aspirin; Duodenal Ulcer; Female; Fibrinolytic Agents; Humans; Male; Rabeprazole;

2014
PPI vs. teprenone in preventing recurrence of ulcers during low-dose aspirin.
    Alimentary pharmacology & therapeutics, 2014, Volume: 40, Issue:11-12

    Topics: Anti-Ulcer Agents; Aspirin; Duodenal Ulcer; Female; Fibrinolytic Agents; Humans; Male; Rabeprazole;

2014
Rabeprazole: a second-generation proton pump inhibitor in the treatment of acid-related disease.
    Expert review of gastroenterology & hepatology, 2008, Volume: 2, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Barrett Esophagus; Gastroesophageal Reflux; Humans; Proton

2008
[The first results of the program Effective Eradication in Novosibirsk].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2008, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Cities; Helicobacter Infections; Helicob

2008
Management of acute peptic ulcers: how ethnicity, different proton pump inhibitors and mechanism of delivery alter the equation.
    Journal of gastroenterology and hepatology, 2009, Volume: 24, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Asian People; Drug Administration Sch

2009
[Combined therapy of acid-dependent gastrointestinal disorders with the use of antacidic drug Relcer].
    Klinicheskaia meditsina, 2009, Volume: 87, Issue:8

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Antacids; Anti-Bacterial Agents; A

2009
Efficacy and safety of rabeprazole in non-steroidal anti-inflammatory drug-induced ulcer in Japan.
    World journal of gastroenterology, 2009, Oct-28, Volume: 15, Issue:40

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diclo

2009
Prospective single-arm trial of two-week rabeprazole treatment for ulcer healing after gastric endoscopic submucosal dissection.
    Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society, 2012, Volume: 24, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Carcinom

2012
[Case report: patient with central nervous system side effects due to lafutidine].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 2012, Jul-10, Volume: 101, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acetamides; Anti-Ulcer Agents; Central Nervous System Disea

2012
Refractory ulcer of reconstructed gastric tube after esophagectomy: a case report.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2013, Volume: 19, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aryl Hydrocarbon Hydroxylases; Carcinoma, Squamous Cell; Cy

2013
[Seven-day antihelicobacter therapy of duodenal ulcer associated with Helicobacter pylori and prospects for treating patients].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2002, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Amoxicillin; Benzimidazoles; Clarithromycin; Drug Ad

2002
[Pariet in eradication therapy plans].
    Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, 2002, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Bacterial Agents; Anti-Ulcer Agents; Benzimidazoles; D

2002
A new furoxan NO-donor rabeprazole derivative and related compounds.
    Chembiochem : a European journal of chemical biology, 2003, Sep-05, Volume: 4, Issue:9

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Benzimidazoles; Drug Design; He

2003
Efficacy of triple therapy with rabeprazole for Helicobacter pylori infection in relation to CYP2C19 genotype.
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2003, Volume: 42, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer

2003
Monocyte chemotactic protein-1 regulates leukocyte recruitment during gastric ulcer recurrence induced by tumor necrosis factor-alpha.
    American journal of physiology. Gastrointestinal and liver physiology, 2004, Volume: 287, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulce

2004
Effects of antisecretory agents on angiogenesis during healing of gastric ulcers.
    Journal of gastroenterology, 2005, Volume: 40, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Base Sequence; Benzimidazoles; Biopsy, Needle; Case-

2005
Effects of sucralfate, cimetidine and rabeprazole on mucosal hydroxyproline content in healing of ethanol-hcl-induced gastric lesions.
    Clinical and experimental pharmacology & physiology, 2006, Volume: 33, Issue:7

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Ulcer Agents; Cimetidine; Ethanol; Gastric Mu

2006
Gastric mucosal levels of prostaglandins and leukotrienes in patients with gastric ulcer after treatment with rabeprazole in comparison to treatment with ranitidine.
    The journal of medical investigation : JMI, 2007, Volume: 54, Issue:1-2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; 6-Ketoprostaglandin F1 alpha; Adult; Aged; Cyclooxygenase 2

2007
[Proton-pump inhibitor Rabeprazole: faster acid- and symptom-control].
    Deutsche medizinische Wochenschrift (1946), 1998, Nov-20, Volume: 123, Issue:47 Suppl

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Anti-Ulcer Agents; Benzimidazoles; Duodenal Ulcer; Gastroes

1998
Bile reflux due to disturbed gastric movement is a cause of spontaneous gastric ulcer in W/Wv mice.
    Digestive diseases and sciences, 1999, Volume: 44, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Administration, Oral; Animals; Anti-Ulcer Agents; Benzimida

1999
Cytoprotective effect of rabeprazole against ethanol-induced gastric mucosal damage: possible involvement of nitric oxide.
    Drugs under experimental and clinical research, 2000, Volume: 26, Issue:2

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulce

2000
[Pharma-clinics medication of the month. Rabeprazole (Pariet)].
    Revue medicale de Liege, 2002, Volume: 57, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Benzimidazoles; Clinical Trials as Topic; Duodenal Ulcer; E

2002
Effects of histamine H2-receptor antagonists and a proton pump inhibitor on the mucosal hydroxyproline content of ethanol-HCl-induced gastric lesions in rats.
    Digestion, 1992, Volume: 51, Issue:3

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Animals; Anti-Ulcer Agents; Benz

1992
Effects of two benzimidazoles as proton pump inhibitors on water immersion stress-induced gastric ulcers in rats.
    Arzneimittel-Forschung, 1991, Volume: 41, Issue:6

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adenosine Triphosphatases; Animals; Benzimidazoles; Gastric

1991