Page last updated: 2024-11-03

rabeprazole and Benign Neoplasms

rabeprazole has been researched along with Benign Neoplasms in 5 studies

Rabeprazole: A 4-(3-methoxypropoxy)-3-methylpyridinyl derivative of timoprazole that is used in the therapy of STOMACH ULCERS and ZOLLINGER-ELLISON SYNDROME. The drug inhibits H(+)-K(+)-EXCHANGING ATPASE which is found in GASTRIC PARIETAL CELLS.

Research Excerpts

ExcerptRelevanceReference
"We found that E-3810 remained active in tumors rendered nonresponsive to the general kinase inhibitor sunitinib resulting from a previous cycle of sunitinib treatment."1.37E-3810 is a potent dual inhibitor of VEGFR and FGFR that exerts antitumor activity in multiple preclinical models. ( Bello, E; Berndt, A; Camboni, G; Cavalletti, E; Colella, G; D'Incalci, M; Damia, G; Giavazzi, R; Oliva, P; Scarlato, V; Serra, SC; Valbusa, G, 2011)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bello, E1
Colella, G1
Scarlato, V1
Oliva, P1
Berndt, A1
Valbusa, G1
Serra, SC1
D'Incalci, M2
Cavalletti, E1
Giavazzi, R1
Damia, G1
Camboni, G1
Sala, F1
Bagnati, R1
Livi, V1
Cereda, R1
Zucchetti, M1
Domeki, Y1
Yamazaki, E1
Matsuura, A1
Kitajima, K1
Murakami, K1
Kato, H1
Miao, ZH1
Feng, JM1
Ding, J1
Sheptulin, AA1

Reviews

2 reviews available for rabeprazole and Benign Neoplasms

ArticleYear
Newly discovered angiogenesis inhibitors and their mechanisms of action.
    Acta pharmacologica Sinica, 2012, Volume: 33, Issue:9

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Diterpenes; Drug Design; Drug Resistance, N

2012
[Safety profile of pariet clinical use (a literature review)].
    Voenno-meditsinskii zhurnal, 2001, Volume: 322, Issue:5

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Aged; Benzimidazoles; Drug Interactions; Enzyme Inhibitors;

2001

Trials

2 trials available for rabeprazole and Benign Neoplasms

ArticleYear
Development and validation of a high-performance liquid chromatography-tandem mass spectrometry method for the determination of the novel inhibitor of angiogenesis E-3810 in human plasma and its application in a clinical pharmacokinetic study.
    Journal of mass spectrometry : JMS, 2011, Volume: 46, Issue:10

    Topics: Angiogenesis Inhibitors; Calibration; Chromatography, High Pressure Liquid; Humans; Limit of Detecti

2011
Effects of a proton pump inhibitor on the physiological accumulation of fluoro-2-deoxy-D-glucose (FDG) in FDG-positron emission tomography.
    Surgery today, 2012, Volume: 42, Issue:10

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Aged, 80 and over; Colon; Drug Administration

2012

Other Studies

1 other study available for rabeprazole and Benign Neoplasms

ArticleYear
E-3810 is a potent dual inhibitor of VEGFR and FGFR that exerts antitumor activity in multiple preclinical models.
    Cancer research, 2011, Feb-15, Volume: 71, Issue:4

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Animals; Antineoplastic Agents; Cells, Cultured; Drug Evalu

2011