r 59022 has been researched along with Leukemia, T-Cell in 1 studies
R 59022: diacylglycerol kinase inhibitor; structure given in first source; platelet activator factor antagonist
Leukemia, T-Cell: A malignant disease of the T-LYMPHOCYTES in the bone marrow, thymus, and/or blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with thapsigargin, a microsomal Ca2+-ATPase inhibitor, abolished the rises of [Ca2+]i induced by the subsequent addition of sphingosine, OKT3, and PA in the absence of extracellular Ca2+." | 1.29 | Ca2+ mobilizing action of sphingosine in Jurkat human leukemia T cells. Evidence that sphingosine releases Ca2+ from inositol trisphosphate- and phosphatidic acid-sensitive intracellular stores through a mechanism independent of inositol trisphosphate. ( Imoto, K; Kaneko, M; Ohshika, H; Sakano, S; Takemura, H; Yamada, K, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sakano, S | 1 |
| Takemura, H | 1 |
| Yamada, K | 1 |
| Imoto, K | 1 |
| Kaneko, M | 1 |
| Ohshika, H | 1 |
1 other study available for r 59022 and Leukemia, T-Cell
| Article | Year |
|---|---|
Ca2+ mobilizing action of sphingosine in Jurkat human leukemia T cells. Evidence that sphingosine releases Ca2+ from inositol trisphosphate- and phosphatidic acid-sensitive intracellular stores through a mechanism independent of inositol trisphosphate.
Topics: Amines; Calcium; Cell Line; Ceramides; Diacylglycerol Kinase; Diglycerides; Enzyme Inhibitors; Human | 1996 |