qx-314 has been researched along with Neuralgia in 4 studies
QX-314: triethyl analog of lidocaine; RN & NM refer to ion
Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We concluded that only peripheral blockade of transient receptor potential vanilloid receptor 1-expressing nociceptive afferents by the QX-314/capsaicin combination was effective at reducing neuropathic allodynia and hyperalgesia." | 3.78 | Differential effects of peripheral versus central coadministration of QX-314 and capsaicin on neuropathic pain in rats. ( Cheng, J; Fox, LE; Shen, J, 2012) |
| "Mechanical allodynia, induced by normally innocuous low-threshold mechanical stimulation, represents a cardinal feature of neuropathic pain." | 1.42 | Inhibition of mechanical allodynia in neuropathic pain by TLR5-mediated A-fiber blockade. ( Bang, S; Berta, T; Ji, RR; Kim, YH; Oh, SB; Wang, F; Xu, ZZ; Zhang, Y, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xu, ZZ | 1 |
| Kim, YH | 1 |
| Bang, S | 1 |
| Zhang, Y | 1 |
| Berta, T | 1 |
| Wang, F | 1 |
| Oh, SB | 1 |
| Ji, RR | 1 |
| Peirs, C | 1 |
| Seal, RP | 1 |
| Shen, J | 1 |
| Fox, LE | 1 |
| Cheng, J | 1 |
| Zakir, HM | 1 |
| Mostafeezur, RM | 1 |
| Suzuki, A | 1 |
| Hitomi, S | 1 |
| Suzuki, I | 1 |
| Maeda, T | 1 |
| Seo, K | 1 |
| Yamada, Y | 1 |
| Yamamura, K | 1 |
| Lev, S | 1 |
| Binshtok, AM | 1 |
| Iwata, K | 1 |
| Kitagawa, J | 1 |
4 other studies available for qx-314 and Neuralgia
| Article | Year |
|---|---|
Inhibition of mechanical allodynia in neuropathic pain by TLR5-mediated A-fiber blockade.
Topics: Adult; Aged; Anesthetics, Local; Animals; Antineoplastic Agents; Capsaicin; Diabetic Neuropathies; F | 2015 |
Targeting Toll-like receptors to treat chronic pain.
Topics: Anesthetics, Local; Animals; Chronic Pain; Flagellin; Humans; Hyperalgesia; Lidocaine; Mice; Nerve F | 2015 |
Differential effects of peripheral versus central coadministration of QX-314 and capsaicin on neuropathic pain in rats.
Topics: Anesthetics, Local; Animals; Antipruritics; Capsaicin; Disease Models, Animal; Drug Administration R | 2012 |
Expression of TRPV1 channels after nerve injury provides an essential delivery tool for neuropathic pain attenuation.
Topics: Anesthetics, Local; Animals; Capsaicin; Gene Expression; Hyperalgesia; Lidocaine; Male; Mandibular N | 2012 |