Page last updated: 2024-11-03

quipazine and Muscle Contraction

quipazine has been researched along with Muscle Contraction in 13 studies

Quipazine: A pharmacologic congener of serotonin that contracts smooth muscle and has actions similar to those of tricyclic antidepressants. It has been proposed as an oxytocic.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
"Quipazine was also effective when administered into a lateral cerebral ventricle."1.27Effects of serotonin agonists on lordosis, myoclonus, and cytoplasmic progestin receptors in guinea pigs. ( Feder, HH; O'Connor, LH, 1983)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19907 (53.85)18.7374
1990's5 (38.46)18.2507
2000's1 (7.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lumma, WC1
Hartman, RD1
Saari, WS1
Engelhardt, EL1
Hirschmann, R1
Clineschmidt, BV2
Torchiana, ML1
Stone, CA1
Wainscott, DB1
Cohen, ML3
Schenck, KW1
Audia, JE1
Nissen, JS1
Baez, M1
Kursar, JD1
Lucaites, VL1
Nelson, DL1
Dukat, M1
Abdel-Rahman, AA1
Ismaiel, AM1
Ingher, S1
Teitler, M1
Gyermek, L1
Glennon, RA1
Antri, M1
Orsal, D1
Barthe, JY1
Ong, J1
Kerr, DI1
Fuller, RW2
O'Connor, LH1
Feder, HH1
Hong, E1
Wiley, KS1
Wong, EH1
Clark, R1
Leung, E1
Loury, D1
Bonhaus, DW1
Jakeman, L1
Parnes, H1
Whiting, RL1
Eglen, RM1
Alhaider, AA1
Rawlow, A1
King, RG1
Reiss, DR1
Pettibone, DJ1
Robinson, JL1

Other Studies

13 other studies available for quipazine and Muscle Contraction

ArticleYear
Piperazinylpyrazines with central serotoninmimetic activity.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:6

    Topics: Animals; Central Nervous System; Female; In Vitro Techniques; Mice; Molecular Conformation; Muscle C

1978
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate;

1993
Structure-activity relationships for the binding of arylpiperazines and arylbiguanides at 5-HT3 serotonin receptors.
    Journal of medicinal chemistry, 1996, Sep-27, Volume: 39, Issue:20

    Topics: Animals; Biguanides; Heart Rate; Male; Molecular Structure; Muscle Contraction; Piperazines; Rabbits

1996
Locomotor recovery in the chronic spinal rat: effects of long-term treatment with a 5-HT2 agonist.
    The European journal of neuroscience, 2002, Volume: 16, Issue:3

    Topics: Animals; Drug Administration Schedule; Electromyography; Female; Hindlimb; Locomotion; Muscle Contra

2002
Evidence that 5-hydroxytryptamine does not mediate GABA-induced contractile responses in the guinea-pig proximal ileum.
    European journal of pharmacology, 1984, Nov-27, Volume: 106, Issue:3

    Topics: Acetylcholine; Animals; Female; gamma-Aminobutyric Acid; Guinea Pigs; Ileum; In Vitro Techniques; Ma

1984
Antagonism of vascular serotonin receptors by m-chlorophenylpiperazine and m-trifluoromethylphenylpiperazine.
    Life sciences, 1983, Feb-14, Volume: 32, Issue:7

    Topics: Animals; Depression, Chemical; Jugular Veins; Male; Muscle Contraction; Muscle, Smooth, Vascular; Pi

1983
Effects of serotonin agonists on lordosis, myoclonus, and cytoplasmic progestin receptors in guinea pigs.
    Hormones and behavior, 1983, Volume: 17, Issue:2

    Topics: Animals; Cytoplasm; Dose-Response Relationship, Drug; Estradiol; Female; Fenfluramine; Guinea Pigs;

1983
[Excellence of quipazine in the characterization of serotoninergic receptors and mechanisms].
    Gaceta medica de Mexico, 1982, Volume: 118, Issue:4

    Topics: Animals; Behavior, Animal; Cats; Chemical Phenomena; Chemistry; Guinea Pigs; Humans; Muscle Contract

1982
Evidence for 5-HT2 receptors mediating contraction in vascular smooth muscle.
    The Journal of pharmacology and experimental therapeutics, 1981, Volume: 218, Issue:2

    Topics: Animals; Aorta; In Vitro Techniques; Jugular Veins; Male; Muscle Contraction; Muscle, Smooth, Vascul

1981
The interaction of RS 25259-197, a potent and selective antagonist, with 5-HT3 receptors, in vitro.
    British journal of pharmacology, 1995, Volume: 114, Issue:4

    Topics: Animals; Autoradiography; Binding, Competitive; Brain; Guinea Pigs; Ileum; In Vitro Techniques; Isoq

1995
Anticholinergic, antihistaminic and cardiovascular effects of two new congeners of quipazine and trazodone.
    Arzneimittel-Forschung, 1993, Volume: 43, Issue:11

    Topics: Animals; Blood Pressure; Cardiovascular Agents; Electrocardiography; Female; Guinea Pigs; Histamine

1993
A novel in vivo test for drugs affecting central serotonergic and adrenergic systems.
    European journal of pharmacology, 1990, Dec-04, Volume: 191, Issue:3

    Topics: 5-Hydroxytryptophan; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Albuterol; Animals; Cl

1990
Characterization of 5-hydroxytryptamine receptors in rat stomach fundus.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:3

    Topics: Animals; Binding, Competitive; Brain Chemistry; Gastric Fundus; In Vitro Techniques; Ketanserin; Mal

1985