quipazine has been researched along with Glioma in 4 studies
Quipazine: A pharmacologic congener of serotonin that contracts smooth muscle and has actions similar to those of tricyclic antidepressants. It has been proposed as an oxytocic.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pharmacological characteristics of 5-HT3 receptor (5-hydroxytryptamine3 receptor) recognition sites labelled with [3H]-(S)-zacopride and [3H]granisetron in membranes prepared from NG108-15 neuroblastoma-glioma cells were directly compared to investigate further differences in the binding characteristics of these two radioligands." | 7.68 | Differential binding characteristics of agonists at 5-HT3 receptor recognition sites in NG108-15 neuroblastoma-glioma cells labelled by [3H]-(S)-zacopride and [3H]granisetron. ( Barnes, JM; Barnes, NM, 1993) |
| "Valproic acid (VPA), which has demonstrated efficacy in the treatment of bipolar disorder, has been shown to alter components of the phosphoinositide (PI) signaling cascade and to increase gene expression mediated by the transcription factor activator protein 1 (AP-1)." | 5.32 | Effect of valproic acid on serotonin-2A receptor signaling in C6 glioma cells. ( Burke, T; Hensler, JG; Javors, M; Siafaka-Kapadai, A; Sullivan, NR, 2004) |
| "The pharmacological characteristics of 5-HT3 receptor (5-hydroxytryptamine3 receptor) recognition sites labelled with [3H]-(S)-zacopride and [3H]granisetron in membranes prepared from NG108-15 neuroblastoma-glioma cells were directly compared to investigate further differences in the binding characteristics of these two radioligands." | 3.68 | Differential binding characteristics of agonists at 5-HT3 receptor recognition sites in NG108-15 neuroblastoma-glioma cells labelled by [3H]-(S)-zacopride and [3H]granisetron. ( Barnes, JM; Barnes, NM, 1993) |
| "Valproic acid (VPA), which has demonstrated efficacy in the treatment of bipolar disorder, has been shown to alter components of the phosphoinositide (PI) signaling cascade and to increase gene expression mediated by the transcription factor activator protein 1 (AP-1)." | 1.32 | Effect of valproic acid on serotonin-2A receptor signaling in C6 glioma cells. ( Burke, T; Hensler, JG; Javors, M; Siafaka-Kapadai, A; Sullivan, NR, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rosen, T | 1 |
| Seeger, TF | 1 |
| McLean, S | 1 |
| Nagel, AA | 1 |
| Ives, JL | 1 |
| Guarino, KJ | 1 |
| Bryce, D | 1 |
| Furman, J | 1 |
| Roth, RW | 1 |
| Chalabi, PM | 1 |
| Cappelli, A | 1 |
| Anzini, M | 1 |
| Vomero, S | 1 |
| Mennuni, L | 1 |
| Makovec, F | 1 |
| Doucet, E | 1 |
| Hamon, M | 1 |
| Bruni, G | 1 |
| Romeo, MR | 1 |
| Menziani, MC | 1 |
| De Benedetti, PG | 1 |
| Langer, T | 1 |
| Sullivan, NR | 1 |
| Burke, T | 1 |
| Siafaka-Kapadai, A | 1 |
| Javors, M | 1 |
| Hensler, JG | 1 |
| Barnes, JM | 1 |
| Barnes, NM | 1 |
4 other studies available for quipazine and Glioma
| Article | Year |
|---|---|
Synthesis, in vitro binding profile, and central nervous system penetrability of the highly potent 5-HT3 receptor antagonist [3H]-4-(2-methoxyphenyl)-2-[4(5)-methyl-5(4)-imidazolylmethyl]thiazole.
Topics: Animals; Blood-Brain Barrier; Brain; Chemical Phenomena; Chemistry; Glioma; Imidazoles; Mice; Molecu | 1990 |
Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 1. Mapping the central 5-HT3 receptor binding site by arylpiperazine derivatives.
Topics: Animals; Benzene; Binding Sites; Glioma; Guanidine; Mice; Models, Molecular; Molecular Structure; Ne | 1998 |
Effect of valproic acid on serotonin-2A receptor signaling in C6 glioma cells.
Topics: Animals; Anticonvulsants; Binding Sites; Cell Line; Dose-Response Relationship, Drug; Glioma; Ketans | 2004 |
Differential binding characteristics of agonists at 5-HT3 receptor recognition sites in NG108-15 neuroblastoma-glioma cells labelled by [3H]-(S)-zacopride and [3H]granisetron.
Topics: Animals; Benzamides; Biguanides; Binding Sites; Binding, Competitive; Bridged Bicyclo Compounds; Bri | 1993 |