quipazine and Disease Models, Animal studies

quipazine and Disease Models, Animal

Quipazine: A pharmacologic congener of serotonin that contracts smooth muscle and has actions similar to those of tricyclic antidepressants. It has been proposed as an oxytocic.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

Excerpt	Relevance	Reference
"Both normal and genetically dystonic (dt) rats show a high-frequency forepaw tremor in response to systemic administration of the serotonin (5-HT) agonist quipazine at 8 days of age."	3.68	Enhanced sensitivity to quipazine in the genetically dystonic rat (dt). ( Lorden, JF; Michela, VL; Stratton, SE, 1990)
"Severe spinal cord contusions interrupt nearly all brain projections to lumbar circuits producing leg movement."	1.48	Cortico-reticulo-spinal circuit reorganization enables functional recovery after severe spinal cord contusion. ( Anderson, MA; Anil, S; Asboth, L; Barraud, Q; Batti, L; Baud, L; Beauparlant, J; Courtine, G; Friedli, L; Kreider, J; Martinez-Gonzalez, C; Pagès, S; Pidpruzhnykova, G; Rey, E; Schneider, BL; Shkorbatova, P, 2018)
"Quipazine was particularly effective facilitating hindlimb stepping."	1.42	Neurochemical excitation of thoracic propriospinal neurons improves hindlimb stepping in adult rats with spinal cord lesions. ( Chopek, JW; Cowley, KC; MacNeil, BJ; Schmidt, BJ; Sutherland, S, 2015)
" We hypothesized that the characteristics of the spinally evoked potentials after chronic administration of both strychnine and quipazine under the influence of eEmc during standing and stepping can be used as biomarkers to predict successful motor performance."	1.42	Electrophysiological biomarkers of neuromodulatory strategies to recover motor function after spinal cord injury. ( Choe, J; Creagmile, J; Edgerton, VR; Gad, P; Gerasimenko, Y; Roy, RR; Zhong, H, 2015)
"Cervical incomplete spinal cord injuries often lead to severe and persistent impairments of sensorimotor functions and are clinically the most frequent type of spinal cord injury."	1.37	Motor deficits and recovery in rats with unilateral spinal cord hemisection mimic the Brown-Sequard syndrome. ( Filli, L; Schwab, ME; Weinmann, O; Zörner, B, 2011)
"After complete spinal cord transections that removed all supraspinal inputs in adult rats, combinations of serotonergic agonists and epidural electrical stimulation were able to acutely transform spinal networks from nonfunctional to highly functional and adaptive states as early as 1 week after injury."	1.35	Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. ( Ao, Y; Courtine, G; Edgerton, VR; Gerasimenko, Y; Ichiyama, RM; Lavrov, I; Musienko, P; Roy, RR; Sofroniew, MV; Song, B; van den Brand, R; Yew, A; Zhong, H, 2009)
"Quipazine (i."	1.35	Dose dependence of the 5-HT agonist quipazine in facilitating spinal stepping in the rat with epidural stimulation. ( Edgerton, VR; Gerasimenko, Y; Ichiyama, RM; Jindrich, DL; Roy, RR; Zhong, H, 2008)
"Pretreatment with seganserin, a 5-HT(2) receptor antagonist (2 mg/kg, i."	1.31	Evidence for serotonergic modulation of progesterone-induced hyperphagia, depression and algesia in female mice. ( Kaur, G; Kulkarni, SK, 2002)

Research

Studies (18)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (5.56)	18.7374
1990's	1 (5.56)	18.2507
2000's	7 (38.89)	29.6817
2010's	8 (44.44)	24.3611
2020's	1 (5.56)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

1 (5.56)

18.7374

1990's

1 (5.56)

18.2507

2000's

7 (38.89)

29.6817

2010's

8 (44.44)

24.3611

2020's

1 (5.56)

2.80

Authors

Authors	Studies
Abrams, RPM	1
Yasgar, A	1
Teramoto, T	1
Lee, MH	1
Dorjsuren, D	1
Eastman, RT	1
Malik, N	1
Zakharov, AV	1
Li, W	1
Bachani, M	1
Brimacombe, K	1
Steiner, JP	1
Hall, MD	1
Balasubramanian, A	1
Jadhav, A	1
Padmanabhan, R	1
Simeonov, A	1
Nath, A	1
Asboth, L	1
Friedli, L	1
Beauparlant, J	1
Martinez-Gonzalez, C	1
Anil, S	1
Rey, E	1
Baud, L	1
Pidpruzhnykova, G	1
Anderson, MA	1
Shkorbatova, P	1
Batti, L	1
Pagès, S	1
Kreider, J	1
Schneider, BL	1
Barraud, Q	1
Courtine, G	3
Chopek, JW	2
MacDonell, CW	1
Gardiner, K	1
Gardiner, PF	1
Cowley, KC	1
MacNeil, BJ	1
Sutherland, S	1
Schmidt, BJ	1
Gad, P	1
Roy, RR	5
Choe, J	1
Creagmile, J	1
Zhong, H	5
Gerasimenko, Y	3
Edgerton, VR	5
Foffani, G	1
Shumsky, J	1
Knudsen, EB	2
Ganzer, PD	2
Moxon, KA	2
Sekhar, KV	1
Rao, VS	1
Devambatla, RKV	1
Kumar, MM	1
Ung, RV	1
Landry, ES	2
Rouleau, P	1
Lapointe, NP	1
Rouillard, C	1
Guertin, PA	2
van den Brand, R	1
Yew, A	1
Musienko, P	1
Song, B	1
Ao, Y	1
Ichiyama, RM	3
Lavrov, I	1
Sofroniew, MV	1
Ziegler, MD	1
Filli, L	1
Zörner, B	1
Weinmann, O	1
Schwab, ME	1
Shumsky, JS	1
Gerasimenko, YP	1
Lavrov, IA	1
Cai, L	1
Jindrich, DL	1
Kaur, G	1
Kulkarni, SK	1
Costall, B	1
Naylor, RJ	1
Owen, RT	1
Michela, VL	1
Stratton, SE	1
Lorden, JF	1

Studies

Abrams, RPM

Yasgar, A

Teramoto, T

Lee, MH

Dorjsuren, D

Eastman, RT

Malik, N

Zakharov, AV

Li, W

Bachani, M

Brimacombe, K

Steiner, JP

Hall, MD

Balasubramanian, A

Jadhav, A

Padmanabhan, R

Simeonov, A

Nath, A

Asboth, L

Friedli, L

Beauparlant, J

Martinez-Gonzalez, C

Anil, S

Rey, E

Baud, L

Pidpruzhnykova, G

Anderson, MA

Shkorbatova, P

Batti, L

Pagès, S

Kreider, J

Schneider, BL

Barraud, Q

Courtine, G

Chopek, JW

MacDonell, CW

Gardiner, K

Gardiner, PF

Cowley, KC

MacNeil, BJ

Sutherland, S

Schmidt, BJ

Gad, P

Roy, RR

Choe, J

Creagmile, J

Zhong, H

Gerasimenko, Y

Edgerton, VR

Foffani, G

Shumsky, J

Knudsen, EB

Ganzer, PD

Moxon, KA

Sekhar, KV

Rao, VS

Devambatla, RKV

Kumar, MM

Ung, RV

Landry, ES

Rouleau, P

Lapointe, NP

Rouillard, C

Guertin, PA

van den Brand, R

Yew, A

Musienko, P

Song, B

Ao, Y

Ichiyama, RM

Lavrov, I

Sofroniew, MV

Ziegler, MD

Filli, L

Zörner, B

Weinmann, O

Schwab, ME

Shumsky, JS

Gerasimenko, YP

Lavrov, IA

Cai, L

Jindrich, DL

Kaur, G

Kulkarni, SK

Costall, B

Naylor, RJ

Owen, RT

Michela, VL

Stratton, SE

Lorden, JF

Clinical Trials (6)

Trial Overview

Trial	Enrollment	Study Type	Start Date	Status
Study on Preliminary Safety and Efficacy of the ARC Therapy Using the ARC-IM Lumbar System to Support Mobility in People With Chronic Spinal Cord Injury[NCT05942339]	8 participants (Anticipated)	Interventional	2023-08-31	Not yet recruiting
STIMO-PARKINSON: Study on Feasibility of Targeted Epidural Spinal Stimulation (TESS) to Improve Mobility in Patients With Parkinson's Disease[NCT04956770]	2 participants (Actual)	Interventional	2021-06-14	Active, not recruiting
Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury[NCT04994886]	8 participants (Anticipated)	Interventional	2021-06-08	Recruiting
Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury[NCT05044923]	8 participants (Anticipated)	Interventional	2021-12-31	Recruiting
Epidural Electrical Stimulation to Restore Hemodynamic Stability and Trunk Control in People With Spinal Cord Injury[NCT05111093]	20 participants (Anticipated)	Interventional	2021-11-29	Recruiting
Priming With High-Frequency Trans-spinal Stimulation to Augment Locomotor Benefits in Spinal Cord Injury[NCT04807764]	45 participants (Anticipated)	Interventional	2021-08-01	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial

Phase

Enrollment

Study Type

Start Date

Status

Study on Preliminary Safety and Efficacy of the ARC Therapy Using the ARC-IM Lumbar System to Support Mobility in People With Chronic Spinal Cord Injury[NCT05942339]

8 participants (Anticipated)

Interventional

2023-08-31

Not yet recruiting

STIMO-PARKINSON: Study on Feasibility of Targeted Epidural Spinal Stimulation (TESS) to Improve Mobility in Patients With Parkinson's Disease[NCT04956770]

2 participants (Actual)

Interventional

2021-06-14

Active, not recruiting

Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury[NCT04994886]

8 participants (Anticipated)

Interventional

2021-06-08

Recruiting

Restoring Hemodynamic Stability Using Targeted Epidural Spinal Stimulation Following Spinal Cord Injury[NCT05044923]

8 participants (Anticipated)

Interventional

2021-12-31

Recruiting

Epidural Electrical Stimulation to Restore Hemodynamic Stability and Trunk Control in People With Spinal Cord Injury[NCT05111093]

20 participants (Anticipated)

Interventional

2021-11-29

Recruiting

Priming With High-Frequency Trans-spinal Stimulation to Augment Locomotor Benefits in Spinal Cord Injury[NCT04807764]

45 participants (Anticipated)

Interventional

2021-08-01

Recruiting

[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

18 other studies available for quipazine and Disease Models, Animal

Article	Year
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49 Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr	2020
Cortico-reticulo-spinal circuit reorganization enables functional recovery after severe spinal cord contusion. Nature neuroscience, 2018, Volume: 21, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Channelrhodopsins; Disease Models, Animal; F	2018
Daily passive cycling attenuates the hyperexcitability and restores the responsiveness of the extensor monosynaptic reflex to quipazine in the chronic spinally transected rat. Journal of neurotrauma, 2014, Jun-15, Volume: 31, Issue:12 Topics: Animals; Combined Modality Therapy; Disease Models, Animal; Exercise Therapy; Female; Quipazine; Rat	2014
Neurochemical excitation of thoracic propriospinal neurons improves hindlimb stepping in adult rats with spinal cord lesions. Experimental neurology, 2015, Volume: 264 Topics: Animals; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Functional Laterality; Gait	2015
Electrophysiological biomarkers of neuromodulatory strategies to recover motor function after spinal cord injury. Journal of neurophysiology, 2015, May-01, Volume: 113, Issue:9 Topics: Animals; Biomechanical Phenomena; Disease Models, Animal; Electric Stimulation Therapy; Electromyogr	2015
Interactive Effects Between Exercise and Serotonergic Pharmacotherapy on Cortical Reorganization After Spinal Cord Injury. Neurorehabilitation and neural repair, 2016, Volume: 30, Issue:5 Topics: Action Potentials; Analysis of Variance; Animals; Cerebral Cortex; Disease Models, Animal; Exercise	2016
Synthesis and preliminary pharmacological evaluation of N-2-(4-(4-(2-substitutedthiazol-4-yl) piperazin-1-yl)-2-oxoethyl)acetamides as novel atypical antipsychotic agents. Bioorganic & medicinal chemistry letters, 2008, 12-01, Volume: 18, Issue:23 Topics: Acetamides; Animals; Antipsychotic Agents; Combinatorial Chemistry Techniques; Disease Models, Anima	2008
Role of spinal 5-HT2 receptor subtypes in quipazine-induced hindlimb movements after a low-thoracic spinal cord transection. The European journal of neuroscience, 2008, Volume: 28, Issue:11 Topics: Animals; Disease Models, Animal; Hindlimb; Male; Mice; Motor Activity; Movement; Nerve Net; Paralysi	2008
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Transformation of nonfunctional spinal circuits into functional states after the loss of brain input. Nature neuroscience, 2009, Volume: 12, Issue:10 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Biomechanical Phenomena; Brai	2009
Why variability facilitates spinal learning. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Aug-11, Volume: 30, Issue:32 Topics: Algorithms; Animals; Disease Models, Animal; Electromyography; Exercise Therapy; Female; Learning; M	2010
Motor deficits and recovery in rats with unilateral spinal cord hemisection mimic the Brown-Sequard syndrome. Brain : a journal of neurology, 2011, Volume: 134, Issue:Pt 8 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Brown-Sequard Syndrome; Clonidine; Dis	2011
Serotonergic pharmacotherapy promotes cortical reorganization after spinal cord injury. Experimental neurology, 2013, Volume: 241 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Analysis of Variance; Animals; Brain Mapping; Cerebral Corte	2013
Differential effects of 5-HT1 and 5-HT2 receptor agonists on hindlimb movements in paraplegic mice. Progress in neuro-psychopharmacology & biological psychiatry, 2004, Volume: 28, Issue:6 Topics: Analysis of Variance; Animals; Antiparkinson Agents; Disease Models, Animal; Drug Interactions; Exer	2004
Epidural spinal cord stimulation plus quipazine administration enable stepping in complete spinal adult rats. Journal of neurophysiology, 2007, Volume: 98, Issue:5 Topics: Animals; Behavior, Animal; Biomechanical Phenomena; Disease Models, Animal; Dose-Response Relationsh	2007
Dose dependence of the 5-HT agonist quipazine in facilitating spinal stepping in the rat with epidural stimulation. Neuroscience letters, 2008, Jun-27, Volume: 438, Issue:3 Topics: Animals; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimul	2008
Evidence for serotonergic modulation of progesterone-induced hyperphagia, depression and algesia in female mice. Brain research, 2002, Jul-12, Volume: 943, Issue:2 Topics: Analgesics; Animals; Antidepressive Agents, Second-Generation; Brain; Depression; Disease Models, An	2002
Gabaminergic and serotonergic modulation of the antidyskinetic effects of tiapride and oxiperomide in the model using 2-(N,N-dipropyl)animo-5,6-dihydroxytetralin. European journal of pharmacology, 1978, Jun-15, Volume: 49, Issue:4 Topics: 2-Naphthylamine; Aminobutyrates; Animals; Behavior, Animal; Benzamides; Benzimidazoles; Disease Mode	1978
Enhanced sensitivity to quipazine in the genetically dystonic rat (dt). Pharmacology, biochemistry, and behavior, 1990, Volume: 37, Issue:1 Topics: Aging; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Ketanserin; Phen	1990

Article

Year

Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.

Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020

Cortico-reticulo-spinal circuit reorganization enables functional recovery after severe spinal cord contusion.

Nature neuroscience, 2018, Volume: 21, Issue:4

Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Channelrhodopsins; Disease Models, Animal; F

2018

Daily passive cycling attenuates the hyperexcitability and restores the responsiveness of the extensor monosynaptic reflex to quipazine in the chronic spinally transected rat.

Journal of neurotrauma, 2014, Jun-15, Volume: 31, Issue:12

Topics: Animals; Combined Modality Therapy; Disease Models, Animal; Exercise Therapy; Female; Quipazine; Rat

2014

Neurochemical excitation of thoracic propriospinal neurons improves hindlimb stepping in adult rats with spinal cord lesions.

Experimental neurology, 2015, Volume: 264

Topics: Animals; Disease Models, Animal; Excitatory Amino Acid Agonists; Female; Functional Laterality; Gait

2015

Electrophysiological biomarkers of neuromodulatory strategies to recover motor function after spinal cord injury.

Journal of neurophysiology, 2015, May-01, Volume: 113, Issue:9

Topics: Animals; Biomechanical Phenomena; Disease Models, Animal; Electric Stimulation Therapy; Electromyogr

2015

Interactive Effects Between Exercise and Serotonergic Pharmacotherapy on Cortical Reorganization After Spinal Cord Injury.

Neurorehabilitation and neural repair, 2016, Volume: 30, Issue:5

Topics: Action Potentials; Analysis of Variance; Animals; Cerebral Cortex; Disease Models, Animal; Exercise

2016

Synthesis and preliminary pharmacological evaluation of N-2-(4-(4-(2-substitutedthiazol-4-yl) piperazin-1-yl)-2-oxoethyl)acetamides as novel atypical antipsychotic agents.

Bioorganic & medicinal chemistry letters, 2008, 12-01, Volume: 18, Issue:23

Topics: Acetamides; Animals; Antipsychotic Agents; Combinatorial Chemistry Techniques; Disease Models, Anima

2008

Role of spinal 5-HT2 receptor subtypes in quipazine-induced hindlimb movements after a low-thoracic spinal cord transection.

The European journal of neuroscience, 2008, Volume: 28, Issue:11

Topics: Animals; Disease Models, Animal; Hindlimb; Male; Mice; Motor Activity; Movement; Nerve Net; Paralysi

2008

Transformation of nonfunctional spinal circuits into functional states after the loss of brain input.