quinupristin and Pneumonia--Pneumococcal

quinupristin has been researched along with Pneumonia--Pneumococcal* in 1 studies

Other Studies

1 other study(ies) available for quinupristin and Pneumonia--Pneumococcal

Article	Year
Quinupristin-dalfopristin resistance in Streptococcus pneumoniae: novel L22 ribosomal protein mutation in two clinical isolates from the SENTRY antimicrobial surveillance program. Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:8 Resistance to quinupristin-dalfopristin (Q/D) among gram-positive cocci has been very uncommon. Two clinical isolates among 8,837 (0.02%) Streptococcus pneumoniae isolates were discovered in 2001 to 2002 with Q/D MICs of 4 micro g/ml. Each had a 5-amino-acid tandem duplication (RTAHI) in the L22 ribosomal protein gene (rplV) preventing synergistic ribosomal binding of the streptogramin combination. Similar gene duplication has been reported in Q/D-resistant Staphylococcus aureus. Topics: Anti-Bacterial Agents; Base Sequence; Community-Acquired Infections; Drug Resistance, Bacterial; Humans; Molecular Sequence Data; Mutation; Pneumonia, Pneumococcal; Population Surveillance; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Proteins; RNA-Binding Proteins; Streptococcus pneumoniae; United Kingdom; Virginiamycin	2003

Article

Year

Quinupristin-dalfopristin resistance in Streptococcus pneumoniae: novel L22 ribosomal protein mutation in two clinical isolates from the SENTRY antimicrobial surveillance program.

Antimicrobial agents and chemotherapy, 2003, Volume: 47, Issue:8

Resistance to quinupristin-dalfopristin (Q/D) among gram-positive cocci has been very uncommon. Two clinical isolates among 8,837 (0.02%) Streptococcus pneumoniae isolates were discovered in 2001 to 2002 with Q/D MICs of 4 micro g/ml. Each had a 5-amino-acid tandem duplication (RTAHI) in the L22 ribosomal protein gene (rplV) preventing synergistic ribosomal binding of the streptogramin combination. Similar gene duplication has been reported in Q/D-resistant Staphylococcus aureus.

Topics: Anti-Bacterial Agents; Base Sequence; Community-Acquired Infections; Drug Resistance, Bacterial; Humans; Molecular Sequence Data; Mutation; Pneumonia, Pneumococcal; Population Surveillance; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Proteins; RNA-Binding Proteins; Streptococcus pneumoniae; United Kingdom; Virginiamycin

2003